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9 条记录 (耗时 0.013 秒)

    Microorganism isolated from chinese elm (Ulmus sp.) and process for preparing exopolysaccharides by employing the microorganism
    6.
    发明授权
    Microorganism isolated from chinese elm (Ulmus sp.) and process for preparing exopolysaccharides by employing the microorganism 失效
    从榆树（Ulmus sp。）分离的微生物和使用微生物制备胞外多糖的方法

    公开(公告)号：US06727081B2

    公开(公告)日：2004-04-27

    申请号：US09921013

    申请日：2001-07-27

    申请人： Young Lyeol Yang ,  Young Joo Kim

    发明人： Young Lyeol Yang ,  Young Joo Kim

    IPC分类号： C12P1904

    CPC分类号： C12R1/01 ,  A61K31/715 ,  C08B37/00 ,  C12P19/04 ,  Y10S435/822

    摘要： The present invention relates to a novel Enterobacter sp. strain SSYL deposited under accession number KCTC 0687BP isolated from the root bark of Chinese elm, which produces immunostimulating exopolysaccharides with anticancer activity, a process for preparing the exopolysaccharides by fermenting the said microorganism in a culture medium, exopolysaccharides prepared by the process and their uses thereof. The exopolysaccharides of the invention have a molecular weight of 100,000 to 1,000,000 and consist of 40-75% of total sugar, 5-15% of total acidic sugar and 10-25% of total protein. The exopolysaccharides exhibits a high immunoenhancing activity in immune cell proliferation, direct mitogenicity and mixed lymphocyte reaction, and further a high anticancer activity in vivo by virtue of immunostimulation. Moreover, the production of the exopolysaccharides by fermentation of a microorganism, makes it possible to provide the exopolysaccharides with a uniform quality and mass production without destruction of the plant species. The exopolysaccharides of the subject invention have practical uses as an active ingredient for anticancer agents, immunoenhancers and foodstuffs.

    摘要翻译： 本发明涉及一种新型肠杆菌属 以保藏号为KCTC 0687BP的中国榆皮根分离的菌株SSYL，其产生具有抗癌活性的免疫刺激性外多糖，通过在培养基中发酵所述微生物制备外多糖的方法，通过该方法制备的外多糖及其用途 。 本发明的外多糖的分子量为100,000至1,000,000，由总糖的40-75％，总酸性糖的5-15％和总蛋白的10-25％组成。 外多糖在免疫细胞增殖，直接有丝分裂原和混合淋巴细胞反应中表现出高的免疫增强活性，并通过免疫刺激进一步提高体内抗癌活性。 此外，通过微生物的发酵生产外多糖，使得可以提供均匀质量和大量生产的外多糖而不破坏植物物种。 本发明的外多糖作为抗癌剂，免疫增强剂和食品的活性成分具有实用性。

    Continuous fermentation process for the production of metabolities using a moving filter
    9.
    发明授权
    Continuous fermentation process for the production of metabolities using a moving filter 失效
    使用移动过滤器生产代谢物的连续发酵过程

    公开(公告)号：US5688674A

    公开(公告)日：1997-11-18

    申请号：US607482

    申请日：1996-02-27

    申请人： Cha-Yong Choi ,  Young-Lyeol Yang

    发明人： Cha-Yong Choi ,  Young-Lyeol Yang

    IPC分类号： C12P1/00 ,  C12P7/10 ,  C12P7/14 ,  C12P19/14 ,  C12P7/06 ,  C12P7/08

    CPC分类号： C12P19/14 ,  C12P7/10 ,  C12P7/14 ,  Y02E50/16 ,  Y10S435/813 ,  Y10S435/913 ,  Y10S435/94 ,  Y10S435/942

    摘要： A metabolite, e.g., ethanol, is continuously produced from low cost carbohydrate substrates by a process which comprises pulverizing the carbohydrate substrate; liquefying and saccharifying the pulverized substrate; continuously fermenting the lique-saccharified substrate in a fermentor equipped with a moving filter, in the presence of flocculent biological cells maintained at a concentration ranging from 90 to 160 g/l by using the moving filter and a culture medium to produce a fermentation product mixture; and recovering the desired metabolite from the fermentation product mixture.

    摘要翻译： 通过包括粉碎碳水化合物底物的方法从低成本碳水化合物底物连续地生产代谢物，例如乙醇， 液化和糖化粉碎的基材; 在配备有移动过滤器的发酵罐中，在通过使用移动过滤器和培养基保持浓度为90至160g / l的絮凝生物细胞的存在下连续发酵所述液化糖化底物以产生发酵产物混合物 ; 并从发酵产物混合物中回收所需的代谢物。