专利检索 ap:("ABBVIE INC.") AND inv:"Michael L. Curtin" 第 1 页

1.

发明授权
NAMPT inhibitors 有权

公开(公告)号：US09758511B2

公开(公告)日：2017-09-12

申请号：US15048574

申请日：2016-02-19

申请人： AbbVie Inc.

发明人： Michael L. Curtin , Kenton Longenecker , Todd M. Hansen , Richard F. Clark , Bryan Sorensen , Howard R. Heyman , Zhiqin Ji

IPC分类号： C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14 , A61K45/06

CPC分类号： C07D405/14 , A61K45/06 , C07D401/14 , C07D409/14 , C07D417/14

摘要： Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

2.

发明申请
NAMPT INHIBITORS 审中-公开

公开(公告)号：US20170135994A9

公开(公告)日：2017-05-18

申请号：US14878858

申请日：2015-10-08

申请人： AbbVie Inc.

发明人： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman

IPC分类号： A61K31/437 , A61K31/4545 , A61K31/496

CPC分类号： A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00

摘要： Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

3.

发明申请
NAMPT INHIBITORS 审中-公开

公开(公告)号：US20160184282A1

公开(公告)日：2016-06-30

申请号：US14878858

申请日：2015-10-08

申请人： AbbVie Inc.

发明人： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman

IPC分类号： A61K31/437 , A61K31/4545 , A61K31/496

CPC分类号： A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00

摘要： Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

4.

发明授权
NAMPT inhibitors 有权

公开(公告)号：US08975398B2

公开(公告)日：2015-03-10

申请号：US13891357

申请日：2013-05-10

申请人： AbbVie Inc.

发明人： Todd M. Hansen , Kenton Longenecker , Howard R. Heyman , Michael L. Curtin , Richard F. Clark , Bryan Sorensen , Zhiqin Ji , Kevin Woller , George Doherty , Robin Frey

IPC分类号： C07D401/00 , C07D405/14 , A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/5377 , C07D409/14 , C07D417/14 , A61K31/506 , C07D401/14 , C07D401/04 , C07D403/04 , C07D403/14

CPC分类号： A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14

摘要： Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

5.

发明申请
NAMPT INHIBITORS 有权
标题翻译： NAMPT抑制剂

公开(公告)号：US20140336167A1

公开(公告)日：2014-11-13

申请号：US13891338

申请日：2013-05-10

申请人： AbbVie Inc.

发明人： Ramzi F. Sweis , Michael L. Curtin , Marina A. Pliushchev , Todd M. Hansen , Kenton Longenecker

IPC分类号： C07D417/14 , C07D417/12

CPC分类号： A61K31/506 , A61K31/427 , A61K31/4439 , A61K31/496 , A61K31/497 , C07D417/12 , C07D417/14

摘要： Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

摘要翻译： 公开了抑制NAMPT活性的化合物，含有该化合物的组合物和治疗其中NAMPT表达的疾病的方法。

6.

发明申请
SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE 审中-公开

公开(公告)号：US20180071262A1

公开(公告)日：2018-03-15

申请号：US15727220

申请日：2017-10-06

申请人： AbbVie Inc.

发明人： Edward A. Kesicki , Arthur F. Kluge , Michael A. Patane , John H. Van Drie, JR. , Ce Wang , Maricel Torrent , Michael L. Curtin , Todd M. Hansen , Rick F. Clark , Robin R. Frey , Zhiqin Ji , Yujia Dai , William J. McClellan , Jane Gong , Gui-dong G. Zhu , Anthony Mastracchio , Michael R. Michaelides , Thomas D. Penning , Chunqiu C. Lai

IPC分类号： A61K31/4184 , C07D498/10 , C07D403/06 , C07D493/10 , C07D491/107 , C07D263/52 , C07D417/12 , C07D417/04 , C07D413/12 , C07D413/04 , C07D409/12 , C07D407/12 , C07D401/12 , C07D235/02 , C07D413/14 , C07D403/12 , C07D409/06 , C07D405/06 , A61K31/423 , A61K31/4439 , C07D401/06 , C07D495/10

CPC分类号： A61K31/4184 , A61K31/423 , A61K31/4439 , C07D235/02 , C07D263/52 , C07D401/06 , C07D401/12 , C07D403/06 , C07D403/12 , C07D405/06 , C07D407/12 , C07D409/06 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D491/107 , C07D493/10 , C07D495/10 , C07D498/10

摘要： Compounds having a structure of Formula (IX): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1----Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.

7.

发明授权
NAMPT inhibitors 有权

公开(公告)号：US09334264B2

公开(公告)日：2016-05-10

申请号：US13891338

申请日：2013-05-10

申请人： AbbVie Inc.

发明人： Ramzi F. Sweis , Michael L. Curtin , Marina A. Pliushchev , Todd M. Hansen , Kenton Longenecker

IPC分类号： C07D417/14 , C07D417/12

CPC分类号： A61K31/506 , A61K31/427 , A61K31/4439 , A61K31/496 , A61K31/497 , C07D417/12 , C07D417/14

摘要： Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.