摘要:
A DNA fragment containing acyB gene coding for an enzyme capable of acylating the 4"-position of a macrolide antibiotic, said DNA fragment being derived from a microorganism of the genus Streptomyces, having a size of about 3.1 kb and being characterized by the restriction endonuclease map shown in FIG. 1 , and a DNA restriction fragment resulting from digestion with a restriction endonuclease; a recombinant DNA plasmid containing this DNA fragment; a microorganism transformed with this recombinant plasmid; and a process for producing a 4"-acylated macrolide antibiotic by using the transformant.
摘要:
A DNA fragment or a restriction enzyme-digested DNA fragment, the DNA fragment containing a gene, acyA, encoding a 3-acylation enzyme for macrolide antibiotics, characterized by being derived from a strain belonging to the genus Streptomyces, having a size of about 1.8 kb or about 3.2 kb, and having a DNA base sequence shown in a restriction enzyme map shown in FIG. 1(A) or FIG. 1(B), respectively, in the attached drawing. 3-Acylated macrolide antibiotics can be produced advantageously using macrolide antibiotics-producing bacteria transformed with vector plasmids having inserted therein the DNA fragment.
摘要:
The present invention aims at providing a laminated secondary battery in which no short circuit occurs even if an electrode sheet is not covered with an insulating resin. The present invention provides a laminated secondary battery in which positive electrode sheet 21 and a negative electrode sheet are stacked one on the other to face each other with separator 26 interposed therebetween, in which positive electrode sheet 21 or negative electrode sheet or both positive electrode sheet 21 and negative electrode sheet has/have fusion bonded portions 24 fused at intervals along a periphery of positive electrode sheet 21 or the negative electrode sheet, fusion seal portion 25 continuously fused along an inner periphery or an outer periphery of fusion bonded portions 24 or between adjacent fusion bonded portions 24, and separator protrusion portion 28, and the length (L1) of separator protrusion portion 28 satisfies the formula: L1≧L2×C, wherein L2 denotes the dimension of separator 26 in the longitudinal direction except for the length of separator protrusion portion 28, and C denotes the heat shrinkage factor of separator 26 in the longitudinal direction.
摘要:
A film-sealed nonaqueous electrolyte battery comprises: a battery element including a non-aqueous electrolyte; a film case having at least a sealant polymer resin film for sealing the battery element; at least a lead terminal extending from the battery element and projecting from the film case, and the lead terminal with a surface having a contact area in contact directly with the sealant polymer resin film, and at least the contact area of the surface of the lead terminal is coated with an anti-corrosion coating film, wherein the anti-corrosion coating film includes: (A) a polymer of structural units of a phenolic compound, and at least a part of the structural units includes a substituent which comprises an amino group or a substituted amino group; (B) a phosphate compound; and (C) a titanium fluorine compound.