摘要:
Methods and devices for selectively removing an agent from a physiological efferent fluid collection site are provided. A feature of the invention is that a non-occlusive aspiration device is employed to selectively remove the target agent from the site only when the target agent is present in the site. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.
摘要:
Methods and devices for producing turbulence in vascular blood flow are provided. In practicing the subject methods, a blood flow modulator is positioned on an external site of a blood vessel at a location in relation to, e.g., at least proximal to a branched vascular site in a manner sufficient to produce turbulence in blood flow at a target site, e.g., at or immediately proximal to the branched vascular site. Representative blood flow modulation devices that find use in the subject methods are devices that can be positioned on an external site of a blood vessel to produce an annular structure around the blood vessel, where the annular structure includes an inner surface protuberance of sufficient dimensions to produce turbulence in the blood vessel. Also provided are kits and systems for practicing the subject methods. The subject methods and devices find use in a variety of applications, including applications to reduce the risk of emboli entering branch blood vessels from a main blood vessel.
摘要:
The present disclosure relates to one or more methods and apparatus to dispose one or more markers within a subterranean formation. The method includes positioning a drill probe assembly in a borehole extending into the subterranean formation, drilling a hole through a sidewall of the borehole with a flexible shaft of the drill probe assembly, the hole penetrating the subterranean formation, and disposing a marker in the hole.
摘要:
A method for determining the size of tubular pipe to be inserted into an interval of cased or uncased borehole is disclosed. The position of the borehole wall or innermost casing surface in the interval is determined and a window length that is less than the length of the interval is defined. A series of windows along the interval is defined and for each window, the determined position of the borehole wall in that window is used to define a polygon, the edges of which are defined by the parts of the borehole wall closest to the borehole axis in that window. The maximum size of pipe diameter that will fit inside the polygon in each window without intersecting the edges is determined and the size of pipe to be inserted into the interval selected based on the maximum size of diameter pipe determined for each window.
摘要:
An assembly for positioning a well access line in a well. The assembly is located between a supply of well access line and a well, with the line running through the assembly and to the well. Multiple pulleys are incorporated into the assembly about which a well access line such as a conventional wireline may be wrapped. The pulleys are biased to one another such that slack in the line may be stored at the assembly and drawn on in the event of line tension spiking up to a predetermined amount. As such, tension in the line may be kept to a minimum so as to avoid damage to the line during a well access operation. Furthermore, should the tension in the line fail to come back down to below the predetermined amount, the well access operation may be halted in an automated manner. Halting may proceed while continuing to allow take-up of the slack in the line until completed halting of the operation is achieved.
摘要:
Systems and methods for treating internal tissue defects, such as septal defects, with clip-based devices are provided. An exemplary clip-based device includes a tubular body having at least a first and a second deflectable member coupled thereto. The first and second members are coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each member extends outwardly away from the tubular body in a position configured to abut a tissue surface. The first and second members are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall.
摘要:
An acoustic detection of a discrete acoustic signal allows to detect a leak behind a casing (23) of a borehole. An acoustic amplitude (AA) is sampled during a recording time period (24; 64) at a determined position along the tube. Time intervals (26; 66) are defined inside of the recording time period (24), and for each time interval (26) the measured acoustic amplitudes are processed to obtain respectively a corresponding power-frequency spectrum (261). A plurality of the power-frequency spectra are analyzed to identify the discrete acoustic signal by detecting time and frequency dependant changes of power. Preferably the processing involves a Fourier transform analysis. A power-frequency time plot is used to conveniently identify the discrete acoustic event.
摘要:
A biochip well is disclosed, including a vessel containing a well therewithin, the vessel forming at least base and side walls of the well and defining at least one aperture giving access to the well, and further including retaining means for holding a biochip at a predetermined position within the well, the well including a laterally offset region into which the biochip does not protrude when held at the predetermined position by the retaining means. Also disclosed are sealed well assemblies and apparatus and methods for opening sealed wells.
摘要:
The invention relates to an immunoassay method and kit for the indirect detection of chloral hydrate. The invention is underpinned by a novel immunogen that produces an antibody that is specific for the chloral hydrate metabolite trichloroethanol glucuronide. Detection and quantification of trichloroethanol glucuronide has important applications in clinical toxicology, drug facilitated crime, water testing and solvent exposure.
摘要:
An assembly for monitoring load on a drum during an operation in a well with a well access line deployed from the drum. The assembly may include multiple line detection mechanisms for acquiring real-time information relative to dynamic characteristics of the lone over the course of the operation. The assembly also includes a processor for computing the real-time information in light of pre-stored information relative to physical characteristics of the line and the drum. As a result, real-time monitoring of a load on the drum may be achieved. Thus, the operation may be adjusted in real-time as necessary to avoid over-loading of the drum. Additionally, a drum load history may be recorded so as to better account for the true condition of the drum following successive operations.