Compliant tissue sealants
    7.
    发明授权
    Compliant tissue sealants 有权
    符合组织密封剂

    公开(公告)号:US07238364B2

    公开(公告)日:2007-07-03

    申请号:US10338933

    申请日:2003-01-07

    摘要: An improved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, the system is compliant, in that it is capable of conforming to the three dimensional structure of a tissue surface as the tissue bends and deforms during healing processes. The barrier or drug delivery systems is formed as a polymeric coating on tissue surfaces by applied a polymerizable monomer to the surface, and then polymerizing the monomer. The polymerized compliant coating preferably is biodegradable and biocompatible, and can be designed with selected properties of compliancy and elasticity for different surgical and therapeutic applications.

    摘要翻译: 公开了与施加的表面高度附着的改进的屏障或药物递送系统,以及用于制造屏障的方法。 在优选实施例中,该系统是符合的,因为当组织在愈合过程中弯曲并变形时,其能够符合组织表面的三维结构。 通过将可聚合单体施加到表面上,然后聚合单体,将屏障或药物递送系统形成为组织表面上的聚合物涂层。 聚合的柔顺涂层优选是可生物降解和生物相容的,并且可以设计成具有选择的适应性和弹性性质,用于不同的手术和治疗应用。