-
公开(公告)号：US08114885B2
公开(公告)日：2012-02-14
申请号：US11830608
申请日：2007-07-30
申请人： Amogh Boloor , Mui Cheung , Philip Anthony Harris , Kevin Hinkle , Jeffery Alan Stafford , James Marvin Veal
发明人： Amogh Boloor , Mui Cheung , Philip Anthony Harris , Kevin Hinkle , Jeffery Alan Stafford , James Marvin Veal
IPC分类号： C07D239/48 , A61K31/506 , A61P35/00
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US07858626B2
公开(公告)日：2010-12-28
申请号：US11830024
申请日：2007-07-30
申请人： Amogh Boloor , Mui Cheung , Ronda Gayle Davis-Ward , Philip Anthony Harris , Kevin Hinkle , Christopher P. Lauderman , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
发明人： Amogh Boloor , Mui Cheung , Ronda Gayle Davis-Ward , Philip Anthony Harris , Kevin Hinkle , Christopher P. Lauderman , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
IPC分类号： C07D403/04 , A61K31/53 , A61P35/00
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US20100105712A1
公开(公告)日：2010-04-29
申请号：US12609398
申请日：2009-10-30
申请人： Amogh Boloor , Mui Cheung , Philip Anthony Harris , Kevin Hinkle , Jeffery Alan Stafford , James Marvin Veal
发明人： Amogh Boloor , Mui Cheung , Philip Anthony Harris , Kevin Hinkle , Jeffery Alan Stafford , James Marvin Veal
IPC分类号： A61K31/506 , A61P7/00 , A61P27/10 , C07D403/12
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US07105530B2
公开(公告)日：2006-09-12
申请号：US10451305
申请日：2001-12-19
申请人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Anthony Harris , Kevin Hinkle , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
发明人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Anthony Harris , Kevin Hinkle , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
IPC分类号： C07D239/48 , A61K31/506 , A61P27/02
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also Includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US07262203B2
公开(公告)日：2007-08-28
申请号：US11383229
申请日：2006-05-15
申请人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Anthony Harris , Kevin Hinkle , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
发明人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Anthony Harris , Kevin Hinkle , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
IPC分类号： C07D239/48 , C07D403/04 , A61K31/506 , A61P27/02
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US20120277258A1
公开(公告)日：2012-11-01
申请号：US13545029
申请日：2012-07-10
申请人： Amogh Boloor , Mui Cheung , Philip Anthony Harris , Kevin Hinkle , Christopher P. Laudeman , Jeffrey Alan Stafford , James Marvin Veal
发明人： Amogh Boloor , Mui Cheung , Philip Anthony Harris , Kevin Hinkle , Christopher P. Laudeman , Jeffrey Alan Stafford , James Marvin Veal
IPC分类号： A61K31/506 , A61P35/00
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US20070015756A1
公开(公告)日：2007-01-18
申请号：US11383229
申请日：2006-05-15
申请人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
发明人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
IPC分类号： A61K31/53 , A61K31/506 , C07D403/02
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US20070292513A1
公开(公告)日：2007-12-20
申请号：US11830608
申请日：2007-07-30
申请人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
发明人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
IPC分类号： C07D403/12 , A61K31/506 , A61K9/28 , A61P35/00 , C07D231/56
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
-
公开(公告)号：US20070270427A1
公开(公告)日：2007-11-22
申请号：US11830024
申请日：2007-07-30
申请人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
发明人： Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
IPC分类号： A61K31/53 , A61P35/00 , C07D401/12
CPC分类号： C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要： Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
-
公开(公告)号：US07238813B2
公开(公告)日：2007-07-03
申请号：US10433128
申请日：2001-11-28
申请人： Mui Cheung , Philip Anthony Harris , Masaichi Hasegawa , Satoru Ida , Kazuya Kano , Naohiko Nishigaki , Hideyuki Sato , James Marvin Veal , Yoshiaki Washio , Rob I. West
发明人： Mui Cheung , Philip Anthony Harris , Masaichi Hasegawa , Satoru Ida , Kazuya Kano , Naohiko Nishigaki , Hideyuki Sato , James Marvin Veal , Yoshiaki Washio , Rob I. West
IPC分类号： A61K31/4184 , C07D235/30
CPC分类号： C07D249/08 , C07D231/12 , C07D233/56 , C07D235/30 , C07D235/32 , C07D263/58 , C07D277/82 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/14 , C07D487/04
摘要： Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译： 本文描述了可用作TIE-2和/或VEGFR2抑制剂的苯并咪唑衍生物。 所述的发明还包括制备这种苯并咪唑衍生物的方法以及使用它们在治疗过度增殖性疾病中的方法。
-
-
-
-
-
-
-
-
-
搜索结果
64 条记录 (耗时 0.033 秒)
