摘要:
A substrate is provided. A first dielectric layer is formed over the substrate by deposition. Etching stop layer and a second dielectric layer are formed in turn over the first dielectric. Next, the second dielectric layer is dealt with Lewis acid. Then, a first photoresist layer is defined and formed over the second dielectric layer. And then dry etching is carried out by means of the first photoresist layer as the mask to form a via hole. The surface of the second dielectric layer and the via hole are treated with Lewis acid. Subsequently, the second photoresist layer is defined and formed on the second dielectric layer. Dry etching is proceed, and etching stop layer is as a etching terminal point to remove exposed partial surface of the second dielectric layer so as to form a trench having larger horizontal size than the via hole. Subsequently, the second photoresist layer is removed to form the opening of the damascene.
摘要:
This invention relates to novel heterocyclic carboxamide derivatives and salts thereof. More particularly, it relates to novel heterocyclic carboxamide derivatives and salts thereof which act as a ROCK inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of ROCK-related disease.
摘要:
Provided is a compound which is useful as an active ingredient for a pharmaceutical having a PKCθ inhibition activity, particularly a pharmaceutical composition for inhibiting acute rejection occurring in transplantation. The present inventors have conducted extensive studies on a compound having a PKCθ inhibition activity, and as a result, they have found that a compound having a structure such as aralkyl and the like on an amino group at the 2-position and also having a structure such as an adamantylalkyl group and the like on an amino group at the 4-position of 2,4-diaminopyrimidine, or a salt thereof has an excellent PKCθ inhibition activity, thereby completing the present invention. The 2,4-diaminopyrimidine compound of the present invention can be used as a PKCθ inhibitor or an inhibitor of acute rejection occurring in transplantation.
摘要:
The present invention has been achieved reflecting such situation, and its object is to provide a manufacturing method of a semiconductor device capable of continuously performing the mounting process which applies a so-called DBG process and a flip chip bonding method, and can contribute to simplify the manufacturing process and to improve the reliability with no void in the product. The manufacturing method of a semiconductor device according to the present invention comprises: laminating a surface protective sheet to a circuit surface side of a wafer formed with grooves which divide each circuit wherein an adhesive film is adhered on the circuit surface of the wafer; reducing the thickness of the wafer and finally dividing the wafer into individual chips by grinding a back face of the wafer; picking up individual chips together with the adhesive film; die-bonding said individual chip to predetermined position of a chip mounting substrate via said adhesive film; fixing the chip to the chip mounting substrate by heating the die-bonded chip having the adhesive film; and applying a static pressure larger than an ambient pressure by 0.05 MPa or more to a stacked body including the adhesive film one or more times, at any point between adhering the wafer to the adhesive film and fixing the chip to the chip mounting substrate.
摘要:
A statistical-data collecting-and-providing apparatus receives, through a statistical-data-acquisition-criterion setting interface, setting of a statistical-data acquisition criterion and setting of a notification destination, which is a destination of statistical data delivery. Subsequently, the statistical-data collecting-and-providing apparatus collects statistical data based on the thus-received statistical-data acquisition criterion. Thereafter, the statistical-data collecting-and-providing apparatus delivers the thus-collected statistical data to a service-providing application server, which is the notification destination received through the statistical-data-acquisition-criterion setting interface.
摘要:
In a liquid dispensing apparatus comprising a dispensing probe for sipping and injecting a liquid sample and a dispensing controller for operating the dispensing probe to ascend, descend and rotate, the liquid dispensing apparatus includes a sample moving device for moving a rack holding the liquid sample, a light beam generator, a photosensor for receiving a light beam reflected from a surface of the liquid sample, a computing unit for computing a liquid surface level based on an output signal from the photosensor, and a controller for controlling operations of those components in a supervising way and processing information necessary for the operations. With the liquid dispensing apparatus, precise information of the liquid surface level can be obtained before the start of the dispensing operation.
摘要:
A foreign matter detecting system which can acquire a clear image and detect a foreign matter with high accuracy based on the acquired image regardless of whether a subject is located far or near from an image capturing device in spite of a depth variation or a level difference. An image capturing unit having an externally controllable focus position is disposed above or below a liquid surface, and a ray of light from an LED is illuminated toward the liquid surface from above or the side at least at a focus position of the image capturing unit so that a foreign matter on the liquid surface causes mirror reflection. The focus position of the image capturing unit is changed over the range from the top of a container containing a liquid to the bottom thereof. At each focus position, an input image from the image capturing unit is taken into an image input unit of an image processing section. An image selecting unit of the image processing section selects an image focused on the liquid surface or a clearest image of the liquid surface from among the input images. An image detecting unit of the image processing section checks the presence and position of the mirror reflection, thereby detecting the foreign matter.
摘要:
A thread joint for a tube which suppresses galling without deteriorating its sealing performance since a sliding distance L.sub.S which expresses a quantity of spiral sliding of sealing portions relative to each other during a tightening period from the start of a contact between the sealing portions until shoulder portions abut each other satisfies the following relationship:Sliding Distance L.sub.S .ltoreq.-0.0093.times. (Tube Outer Diameter).sup.2 +4.73.times. (Tube Outer Diameter).To shorten the sliding distance L.sub.S, the sealing portion of a box portion is formed shorter than the sealing portion of a pin portion. In this case, a circumferential groove may be formed to discharge a dope. Conversely, the sealing portion of the pin portion is formed shorter than the sealing portion of the box portion. In this case, a precedent-stage unthread portion whose inclination is smaller than that of the sealing portion of the pin portion is formed between a male thread and the sealing portion of the pin portion. In addition, tapers of the sealing portions of the pin portion and the box portion are set at 1/6 or larger, and/or, a distance where the sealing portion of the box portion (pin portion) is formed so as to contact a curve which is tangent to the sealing portion of the pin portion (box portion) is 1.45 mm or larger.
摘要:
An adhesive sheet includes a substrate and an energy-ray curable adhesive layer formed on the substrate. The energy-ray curable adhesive layer includes an energy-ray curable acrylic copolymer and a urethane acrylate. The energy-ray curable acrylic copolymer is formed by copolymerizing at least one of either a dialkyl(meth)acrylamide that has an alkyl group with carbon number of not more than 4, a phenol EO modified (meth)acrylate that has an ethylene glycol chain with a phenyl group bonded to the ethylene glycol chain, a (meth)acryloyl morpholine, or a (meth)acrylate that has an aceto-acetoxyl group, in total of 1 to 30 weight percent of all monomers to form the energy-ray curable acrylic copolymer. The energy-ray curable acrylic copolymer further includes a side chain with an unsaturated group.
摘要:
The present invention relate to a method for monitoring a response to a therapy on a mammal having a neurodegenerative or neuroinflammatory disorder. According to a preferred embodiment, the method comprising the steps of:a) imaging the mammal using a radio-labeled peripheral benzodiazepine receptor ligand;b) administrating in the mammal at least one anti-amyloid or anti-neuroinflammatory agent;c) imaging the mammal of step b) using a radio-labeled peripheral benzodiazepine receptor ligand; andd) detecting the level of CNS neuroinflammation by the signals from the radio-labeled peripheral benzodiazepine receptor ligand.