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公开(公告)号：US11956522B2
公开(公告)日：2024-04-09
申请号：US18063946
申请日：2022-12-09
Applicant: BIO-RAD LABORATORIES, INC.
Inventor： Stephen Swihart , Li Lu , Wade Jameson , Evan Thrush , Michael Griffin , Evelio Perez
CPC classification number: H04N23/52 , H04N23/55 , H05K7/20472
Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.
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公开(公告)号：US20150070483A1
公开(公告)日：2015-03-12
申请号：US14477253
申请日：2014-09-04
Applicant: Bio-Rad Laboratories, Inc., LSG-LSD Division
Inventor： Evan Thrush , Evelio Perez , Steve Swihart
CPC classification number: G02B21/361 , G01N21/00 , G01N21/76 , G02B17/023 , G02B21/0008 , G03B15/00 , G03B17/17
Abstract: An imaging assembly for the viewing, imaging, and analysis of biological, chemical, and/or biochemical samples in gels or other substrates, in which an adjustable camera and lens module, a reflex mirror, and a focal plane mirror, are configured to bend or fold an optical path in order to image a target region, and where the optical path can be reflected along non-orthogonal angles. The imaging assembly is configured to reduce the overall size of the imaging apparatus due to the angles at which the mirrors and camera and lens assembly are positioned relative to each other, which allows for the imaging of relatively larger samples in the target region.
Abstract translation: 用于观察，成像和分析凝胶或其它基底中的生物，化学和/或生化样品的成像组件，其中可调节的相机和透镜模块，反射镜和焦平面镜配置成弯曲 或折叠光路以便对目标区域进行成像，并且其中可以沿非正交角度反射光路。 成像组件被配置为由于反射镜和相机和透镜组件相对于彼此定位的角度而减小成像装置的总体尺寸，这允许在目标区域中对相对较大的样本进行成像。
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公开(公告)号：US09310600B2
公开(公告)日：2016-04-12
申请号：US14477253
申请日：2014-09-04
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Evan Thrush , Evelio Perez , Steve Swihart
CPC classification number: G02B21/361 , G01N21/00 , G01N21/76 , G02B17/023 , G02B21/0008 , G03B15/00 , G03B17/17
Abstract: An imaging assembly for the viewing, imaging, and analysis of biological, chemical, and/or biochemical samples in gels or other substrates, in which an adjustable camera and lens module, a reflex mirror, and a focal plane mirror, are configured to bend or fold an optical path in order to image a target region, and where the optical path can be reflected along non-orthogonal angles. The imaging assembly is configured to reduce the overall size of the imaging apparatus due to the angles at which the mirrors and camera and lens assembly are positioned relative to each other, which allows for the imaging of relatively larger samples in the target region.
Abstract translation: 用于观察，成像和分析凝胶或其它基底中的生物，化学和/或生化样品的成像组件，其中可调节的相机和透镜模块，反射镜和焦平面镜配置成弯曲 或折叠光路以便对目标区域进行成像，并且其中可以沿非正交角度反射光路。 成像组件被配置为由于反射镜和相机和透镜组件相对于彼此定位的角度而减小成像装置的总体尺寸，这允许在目标区域中对相对较大的样本进行成像。
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公开(公告)号：US20130223056A1
公开(公告)日：2013-08-29
申请号：US13740590
申请日：2013-01-14
Applicant: Bio-Rad Laboratories, Inc.
Inventor： James W. Hillendahl , Evelio Perez
IPC: F21V21/005 , F21V13/02 , F21V9/08
CPC classification number: F21V21/005 , F21V9/083 , F21V13/02 , G01N21/255 , G01N21/6452 , G01N21/6456 , G01N27/447 , G01N2021/6463 , G01N2021/6471 , G01N2201/06 , G01N2201/0626 , G01N2201/0635
Abstract: A planar sample, particularly of the type used in biological laboratories for detection and sometimes analysis of two-dimensional arrays of proteins, nucleic acids, or other biological species, is illuminated by epi-illumination using optically filtered line lights that are arranged along opposing parallel sides of a rectangle in which the sample array resides, with two coaxial line lights on each side of the rectangle, and the two on any given side being separated by a gap whose optimal width depends on the wavelength band transmitted by the optical filter. Surprisingly, the gap eliminates the peak in intensity at the center of the sample area and the decrease that occurs from the center outward that would otherwise occur with a single continuous filtered line light, producing instead a substantially uniform intensity along the direction parallel to the line lights.
Abstract translation: 平面样品，特别是用于生物实验室中用于检测和有时分析蛋白质，核酸或其他生物物种的二维阵列的类型的样品，通过使用沿着相对的平行排列的光学滤波的线光照射外照射 样品阵列所在的矩形的边，在矩形的每一侧上具有两根同轴线灯，并且任意给定侧上的两根被间隔开，该间隙的最佳宽度取决于由滤光器传输的波长带。 令人惊奇的是，间隙消除了样品区域中心处的强度峰值以及从中心向外发生的减少，否则会出现与单个连续过滤线条光线相反的方向，沿着平行于该线条的方向产生基本均匀的强度 灯光
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公开(公告)号：US20240334032A1
公开(公告)日：2024-10-03
申请号：US18629257
申请日：2024-04-08
Applicant: BIO-RAD LABORATORIES, INC.
Inventor： Stephen Swihart , Li Lu , Wade Jameson , Evan Thrush , Michael Griffin , Evelio Perez
CPC classification number: H04N23/52 , H04N23/55 , H05K7/20472
Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.
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Patent Agency Ranking
公开(公告)号：US11553116B2
公开(公告)日：2023-01-10
申请号：US17108672
申请日：2020-12-01
Applicant: BIO-RAD LABORATORIES, INC.
Inventor： Stephen Swihart , Li Lu , Wade Jameson , Evan Thrush , Michael Griffin , Evelio Perez
Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.
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公开(公告)号：US08985808B2
公开(公告)日：2015-03-24
申请号：US13740590
申请日：2013-01-14
Applicant: Bio-Rad Laboratories, Inc.
Inventor： James W. Hillendahl , Evelio Perez
IPC: F21S4/00 , F21V21/005 , F21V9/08 , F21V13/02 , G01N21/64
CPC classification number: F21V21/005 , F21V9/083 , F21V13/02 , G01N21/255 , G01N21/6452 , G01N21/6456 , G01N27/447 , G01N2021/6463 , G01N2021/6471 , G01N2201/06 , G01N2201/0626 , G01N2201/0635
Abstract: A planar sample, particularly of the type used in biological laboratories for detection and sometimes analysis of two-dimensional arrays of proteins, nucleic acids, or other biological species, is illuminated by epi-illumination using optically filtered line lights that are arranged along opposing parallel sides of a rectangle in which the sample array resides, with two coaxial line lights on each side of the rectangle, and the two on any given side being separated by a gap whose optimal width depends on the wavelength band transmitted by the optical filter. Surprisingly, the gap eliminates the peak in intensity at the center of the sample area and the decrease that occurs from the center outward that would otherwise occur with a single continuous filtered line light, producing instead a substantially uniform intensity along the direction parallel to the line lights.
Abstract translation: 平面样品，特别是用于生物实验室中用于检测和有时分析蛋白质，核酸或其他生物物种的二维阵列的类型的样品，通过使用沿着相对的平行排列的光学滤波的线光照射外照射 样品阵列所在的矩形的边，在矩形的每一侧上具有两根同轴线灯，并且任意给定侧上的两根被间隔开，该间隙的最佳宽度取决于由滤光器传输的波长带。 令人惊奇的是，间隙消除了样品区域中心处的强度峰值以及从中心向外发生的减少，否则会出现与单个连续过滤线条光线相反的方向，沿着平行于该线条的方向产生基本均匀的强度 灯光
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公开(公告)号：US20150029595A1
公开(公告)日：2015-01-29
申请号：US14444709
申请日：2014-07-28
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Steve Swihart , Evan Thrush , Evelio Perez , Kevin McDonald
IPC: G02B15/14
CPC classification number: G02B15/14
Abstract: An imaging assembly for the viewing, imaging, and analysis of chemiluminescent or bioluminescent samples in gels or other substrates, in which an adjustable camera and lens module having a prime or fixed lens or a focusing lens is moved to change the field of view by shifting the focal plane of the camera and lens module. The imaging assembly can also include a mirror to bend or fold the optical path between the camera and lens module and the target area having a sample, in which the mirror can move in the same vertical direction as the camera and lens module. Further, the camera and lens module can be configured to more move in a diagonal direction relative to the location of the imaging target area. The imaging assembly can further have a duct system adaptable to adjust with the movement of the camera and lens module.
Abstract translation: 用于在凝胶或其它基底中观察，成像和分析化学发光或生物发光样品的成像组件，其中具有主要或固定透镜或聚焦透镜的可调节照相机和透镜模块移动以通过移动来改变视场 相机和镜头模块的焦平面。 成像组件还可以包括用于弯曲或折叠相机和透镜模块之间的光路的反射镜和具有样品的目标区域，其中反射镜可以在与相机和透镜模块相同的垂直方向上移动。 此外，相机和透镜模块可以被配置为相对于成像目标区域的位置在对角线方向上更多地移动。 成像组件还可以具有适于根据相机和透镜模块的运动进行调节的管道系统。
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公开(公告)号：US20210176386A1
公开(公告)日：2021-06-10
申请号：US17108672
申请日：2020-12-01
Applicant: BIO-RAD LABORATORIES, INC.
Inventor： Stephen Swihart , Li Lu , Wade Jameson , Evan Thrush , Michael Griffin , Evelio Perez
Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.
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公开(公告)号：US10284756B2
公开(公告)日：2019-05-07
申请号：US15449786
申请日：2017-03-03
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Evelio Perez , Evan P. Thrush , Stephen L. R. Swihart , Brian D. Hall
Abstract: Techniques and systems for implementing fast, fixed-focal-length lens imaging systems for molecular biology or genetics applications are provided. In particular, techniques and structures are provided for allowing for precise alignment of the optical and imaging components of such imaging systems during assembly with a minimal amount of adjustment.
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