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公开(公告)号：US20210350877A1
公开(公告)日：2021-11-11
申请号：US17313707
申请日：2021-05-06
发明人： Rachel R. Spurbeck , Christopher Johnson , Jacob Lilly , Jared M. Schuetter , Patrick H. Wilson
IPC分类号： G16B50/00 , G16B25/00 , C12Q1/70 , B01L3/00 , B01L3/02 , B01L7/00 , A61F13/38 , G01N33/18 , G01N21/78 , G16H10/40 , G16H50/20
摘要： A point of care device, comprises a chamber configured to contain a swab. Once a swab is loaded, the device introduces a buffer into the chamber, then lyses cells collected by the swab. Probes such as padlock probes target a specified content such as a virus (e.g., SARS-CoV-2 RNA) and will bind, splint ligate, and rapidly isothermally amplify (e.g., using rolling circle amplification). Also described is a wastewater pathogen tracking dashboard and schema for detecting and tracking pathogen spread within communities by monitoring microbial and viral RNA.
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公开(公告)号：US20240253096A1
公开(公告)日：2024-08-01
申请号：US18563429
申请日：2022-05-24
发明人： Amy M. Heintz , Jacob Lilly , Christopher Buurma , Ryan W. Daly
CPC分类号： B09B3/35 , B02C18/2283 , B02C23/06 , B09B3/60 , B09B3/70 , C08J11/08 , C08J11/105 , B09B2101/75 , C08J2367/02
摘要： Apparatus, systems (including solvent or enzyme), and methods of degrading plastic are described. Plastic waste is stretched in the presence of solvent. The surface may be further treated to increase hydrophilicity. The resulting plastics can be treated with plastic-degrading enzyme either with microorganisms or direct application of enzyme.
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公开(公告)号：US20200214564A1
公开(公告)日：2020-07-09
申请号：US16597821
申请日：2019-10-09
发明人： Amy M. Heintz , Krenar Shqau , Ramanathan Lalgudi , Patrick Ganzer , Ming Ming Zhang , Jacob Lilly
摘要： The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.
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4.发明授权公开(公告)号：US12109223B2
公开(公告)日：2024-10-08
申请号：US18444146
申请日：2024-02-16
发明人： Anthony D. Duong , Cherry Gupta , Kenneth R. Sims, Jr. , Danielle Huk , Jacob Lilly , Stephanie M. Kute , Mike Koeris
IPC分类号： A61K47/60 , A61K31/7088 , A61K47/69 , C08F293/00 , C12N15/113 , B82Y5/00 , B82Y30/00 , B82Y35/00 , B82Y40/00
CPC分类号： A61K31/7088 , A61K47/60 , A61K47/6935 , C08F293/005 , C12N15/113 , B82Y5/00 , B82Y30/00 , B82Y35/00 , B82Y40/00 , C08F2438/03 , C12N2310/11 , C12N2310/531
摘要： The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.
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公开(公告)号：US11305106B2
公开(公告)日：2022-04-19
申请号：US16597821
申请日：2019-10-09
发明人： Amy M. Heintz , Krenar Shqau , Ramanathan Lalgudi , Patrick Ganzer , Mingming Zhang , Jacob Lilly
摘要： The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.
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公开(公告)号：US20220080187A1
公开(公告)日：2022-03-17
申请号：US17533354
申请日：2021-11-23
发明人： Amy M. Heintz , Krenar Shqau , Ramanathan Lalgudi , Patrick Ganzer , Mingming Zhang , Jacob Lilly
摘要： The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.
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