METHOD FOR THE MANUFACTURE OF NANOPARTICLES ON A CARBON SURFACE AND PRODUCTS THEREFROM
    1.
    发明申请
    METHOD FOR THE MANUFACTURE OF NANOPARTICLES ON A CARBON SURFACE AND PRODUCTS THEREFROM 审中-公开
    碳纳米管在碳表面上的制备方法及其制备方法

    公开(公告)号:US20100316554A1

    公开(公告)日:2010-12-16

    申请号:US12593312

    申请日:2008-03-28

    IPC分类号: C01B31/00

    摘要: The combination of at least one substantially unfunctionalised carbon surface, such as a fullerene, graphite or amorphous carbon, graphene or pre-aligned carbon nanotubes and at least semi-conducting nanoparticle, for example CdSe, CdTe, CdS, InP and/or ZnO or a metallic alloy nanoparticle is described wherein the at least one nanoparticle is directly attached to the substantially unfunctionalised carbon surface. A method for the manufacture of the nanoparticles is also described. This method comprises: —dissolving a cation source in a first organic solvent to produce a cation-containing medium; —adding a plurality of substantially unfunctionalised carbon surfaces to the cation-containing medium to form a cation-carbon mixture; —adding an anion-containing medium to the mixture of the cation-containing medium and carbon surfaces to form a cation-carbon-anion mixture, In the case of alloy nanoparticles, another cation medium is added instead. —leaving the cation-carbon-anion mixture at a temperature of between 60° C. and 300° C. between 10 minutes and 1 week, depending on the system.

    摘要翻译: 至少一种基本上未官能化的碳表面,例如富勒烯,石墨或无定形碳,石墨烯或预对准碳纳米管和至少半导电纳米颗粒,例如CdSe,CdTe,CdS,InP和/或ZnO的组合,或 描述了金属合金纳米颗粒,其中至少一个纳米颗粒直接连接到基本上未功能化的碳表面。 还描述了制造纳米颗粒的方法。 该方法包括:将阳离子源溶解在第一有机溶剂中以产生含阳离子的介质; 将多个基本上未功能化的碳表面添加到含阳离子的介质中以形成阳离子 - 碳混合物; - 将含阴离子的介质添加到含阳离子的介质和碳表面的混合物中以形成阳离子 - 碳 - 阴离子混合物。在合金纳米颗粒的情况下,加入另外的阳离子介质。 根据系统,将阳离子 - 碳阴离子混合物在60℃和300℃之间的温度下在10分钟和1周之间进行。

    MICELLULAR COMBINATION COMPRISING A NANOPARTICLE AND A PLURALITY OF SURFMER LIGANDS
    4.
    发明申请
    MICELLULAR COMBINATION COMPRISING A NANOPARTICLE AND A PLURALITY OF SURFMER LIGANDS 审中-公开
    包含纳米颗粒和多种表面配体的细胞组合

    公开(公告)号:US20130195755A1

    公开(公告)日:2013-08-01

    申请号:US13807348

    申请日:2011-06-28

    摘要: The field of the present invention relates to the stabilisation of nanoparticles in aqueous dispersion and, in particular, the stabilisation of nanoparticles by encapsulating the nanoparticles in a micellular combination. The field of the present invention further relates to a micellular combination of nanoparticles and a method of manufacture of the micellular combination and uses thereof. In a first aspect the present disclosure teaches a micellular combination that allows the stable dispersion of nanoparticles into aqueous environment. The micellular combination comprises at least one nanoparticle in a core of the micellular combination. A plurality of surfactants is co-assembled with a plurality of hydrophobic ligands on the surface of the nanoparticle in such a way that the hydrophilic part of the surfactant forms a hydrophilic shell around the core of the micellular combination.

    摘要翻译: 本发明的领域涉及在水分散体中稳定纳米颗粒,特别涉及通过将纳米颗粒包封在胶束组合中来稳定纳米颗粒。 本发明的领域还涉及纳米颗粒的微胶囊组合和胶束组合的制造方法及其用途。 在第一方面,本公开内容教导了允许纳米颗粒稳定分散到水性环境中的微胶囊组合。 胶束组合包含胶束组合核心中的至少一个纳米颗粒。 多个表面活性剂与纳米颗粒表面上的多个疏水配体共组装,使得表面活性剂的亲水部分在胶束组合的核心周围形成亲水壳。

    Shock absorber component for railway track having pourous rubber
particle core enclosed by cover layer
    7.
    发明授权
    Shock absorber component for railway track having pourous rubber particle core enclosed by cover layer 失效
    铁路轨道的减震器部件,由覆盖层包围的多孔橡胶颗粒芯

    公开(公告)号:US5487501A

    公开(公告)日:1996-01-30

    申请号:US178270

    申请日:1994-01-10

    摘要: A shock absorber component 7 is in the form of a flatly placeable strip, plate or mat and is especially for supporting the track of railroads. The shock absorber component 7 is placed between the superstructure 2 and the roadbed 1 of the track assembly. The shock absorber component 7 includes a core layer 8 having bonded rubber particles 12 and a cover layer 10 made of flexible material. The cover layer 10 surrounds this core layer 8. The rubber particles 12 of the core layer 8 are exclusively porous and the cover layer 10 is made of a compact rubber material. The cover layer 10 is vulcanized to the core layer 8.

    摘要翻译: PCT No.PCT / DE92 / 00541 Sec。 371日期1994年1月10日 102(e)日期1994年1月10日PCT提交1992年6月30日PCT公布。 公开号WO93 / 01355 日期:1993年1月21日。减震器部件7是平坦地放置的条,板或垫的形式,并且特别地用于支撑铁路轨道。 减震器部件7设置在上部结构2和轨道组件的路基1之间。 减震器部件7包括具有粘合橡胶颗粒12的芯层8和由柔性材料制成的覆盖层10。 覆盖层10围绕该芯层8.芯层8的橡胶颗粒12仅是多孔的,并且覆盖层10由紧凑的橡胶材料制成。 将覆盖层10硫化到芯层8。

    VISUALIZATION OF LIPID METABOLISM
    8.
    发明申请
    VISUALIZATION OF LIPID METABOLISM 审中-公开
    脂质代谢的可视化

    公开(公告)号:US20140050668A1

    公开(公告)日:2014-02-20

    申请号:US13980751

    申请日:2012-01-20

    IPC分类号: A61K49/14

    摘要: The present invention relates to the field of in vivo determination of enzyme activity. It also allows visualization of organisms, organs, tissues and cells. In particular, the present invention provides a method of in vivo visualization and a composition suitable for in vivo determination and/or visualization of enzyme activity by methods such as Magnetic Resonance Imaging, also called Magnetic Resonance Tomography (MRI or MRT), or Magnetic Particle Imaging (MPI). In particular, the activity of the enzyme lipoprotein lipase affects the signals received and allows conclusions on the lipid metabolism of an organism, an organ system, an organ, a tissue and a cell of interest, This method can be employed, e.g., for diagnosis of cardiac disorders, of tumor prognosis and of disorders of the lipid metabolism. The composition used comprises superparamagnetic iron oxide nanocrystals (SPIO) incorporated in the core of lipid micelles designated nanosomes.

    摘要翻译: 本发明涉及酶活性的体内测定领域。 它还允许生物,器官,组织和细胞的可视化。 特别地,本发明提供了一种体内可视化方法和适用于体内测定和/或可视化酶活性的组合物,其通过诸如磁共振成像(Magnetic Resonance Imaging),也称为磁共振层析成像(MRI或MRT)或磁性颗粒 成像(MPI)。 特别地,酶脂蛋白脂肪酶的活性影响所接收的信号,并且允许关于生物体,器官系统,器官,组织和感兴趣的细胞的脂质代谢的结论。该方法可用于例如诊断 的心脏疾病,肿瘤预后和脂质代谢紊乱。 所使用的组合物包括掺入指定为纳米体的脂质胶束核心的超顺磁性氧化铁纳米晶体(SPIO)。

    Reactor for the manufacture of nanoparticles
    10.
    发明授权
    Reactor for the manufacture of nanoparticles 有权
    用于制造纳米颗粒的反应器

    公开(公告)号:US09084979B2

    公开(公告)日:2015-07-21

    申请号:US12866739

    申请日:2009-02-11

    IPC分类号: B82Y40/00 B82Y30/00 B01J19/24

    摘要: An apparatus (10) and a method (200) for the manufacture of nanoparticles. The apparatus and the method allows for the nucleation and growth of nanoparticles at independent temperatures. The independent temperatures allow for the growth of nanoparticles in a controlled environment avoiding spontaneous nucleation and allowing particle sizes to be controlled and facilitating the manufacture of particles of a substantially uniform size. Furthermore the apparatus (10) allows for the manufacture of core-shell nanoparticles and core-shell-shell nanoparticles.

    摘要翻译: 一种用于制造纳米颗粒的装置(10)和方法(200)。 该装置和方法允许在独立温度下纳米颗粒的成核和生长。 独立的温度允许在受控环境中的纳米颗粒的生长,避免自发成核并允许控制粒径并促进制造基本上均匀尺寸的颗粒。 此外,装置(10)允许制造核 - 壳纳米颗粒和核 - 壳 - 壳纳米颗粒。