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    CURRENT CONTROLLING CIRCUIT FOR A LIGHT-EMITTING DIODE DRIVER AND PRODUCING METHOD THEREFOR
    1.
    发明申请
    CURRENT CONTROLLING CIRCUIT FOR A LIGHT-EMITTING DIODE DRIVER AND PRODUCING METHOD THEREFOR 有权
    用于发光二极管驱动器的电流控制电路及其制造方法

    公开(公告)号：US20130076252A1

    公开(公告)日：2013-03-28

    申请号：US13548624

    申请日：2012-07-13

    Applicant: Bin Shao ,  Kenji Tomiyoshi

    Inventor： Bin Shao ,  Kenji Tomiyoshi

    IPC: H05B33/08 ,  G05F1/46

    CPC classification number: H05B33/0842 ,  G05F1/46 ,  H05B33/0824

    Abstract: The present disclosure proposes a fully integrated accurate LED output current controlling circuit and method, which can be seamlessly combined with true PWM dimming. The current controlling circuit has an auto zero function in the light-emitting diode driver to eliminate offsets caused by the system, process variations, parasitic effects, dimming and so on in an LED driver application, and thus is capable of controlling the LED current with high accuracy. Moreover, the driver of the present disclosure does not require the use of external components such as an external resistor to regulate current accuracy.

    Abstract translation: 本公开提出了一种完全集成的准确的LED输出电流控制电路和方法，其可以与真实的PWM调光无缝组合。 电流控制电路在发光二极管驱动器中具有自动调零功能，以消除LED驱动器应用中由系统引起的偏移，工艺变化，寄生效应，调光等，从而能够控制LED电流 高准确率。 此外，本公开的驱动器不需要使用诸如外部电阻器的外部组件来调节电流精度。

    Current controlling circuit for a light-emitting diode driver and producing method therefor
    2.
    发明授权
    Current controlling circuit for a light-emitting diode driver and producing method therefor 有权
    一种用于发光二极管驱动器的电流控制电路及其制造方法

    公开(公告)号：US08981667B2

    公开(公告)日：2015-03-17

    申请号：US13548624

    申请日：2012-07-13

    Applicant: Bin Shao ,  Kenji Tomiyoshi

    Inventor： Bin Shao ,  Kenji Tomiyoshi

    IPC: G05F1/00 ,  H05B37/02 ,  H05B39/04 ,  H05B41/36 ,  H05B33/08 ,  G05F1/46

    CPC classification number: H05B33/0842 ,  G05F1/46 ,  H05B33/0824

    Abstract: The present disclosure proposes a fully integrated accurate LED output current controlling circuit and method, which can be seamlessly combined with true PWM dimming. The current controlling circuit has an auto zero function in the light-emitting diode driver to eliminate offsets caused by the system, process variations, parasitic effects, dimming and so on in an LED driver application, and thus is capable of controlling the LED current with high accuracy. Moreover, the driver of the present disclosure does not require the use of external components such as an external resistor to regulate current accuracy.

    Abstract translation: 本公开提出了一种完全集成的准确的LED输出电流控制电路和方法，其可以与真实的PWM调光无缝组合。 电流控制电路在发光二极管驱动器中具有自动调零功能，以消除LED驱动器应用中由系统引起的偏移，工艺变化，寄生效应，调光等，从而能够控制LED电流 高准确率。 此外，本公开的驱动器不需要使用诸如外部电阻器的外部组件来调节电流精度。

    ESD protection circuit for a switching power converter
    3.
    发明授权
    ESD protection circuit for a switching power converter 有权
    用于开关电源转换器的ESD保护电路

    公开(公告)号：US08345394B2

    公开(公告)日：2013-01-01

    申请号：US12573501

    申请日：2009-10-05

    Applicant: James W. Zhao ,  Reed W. Adams ,  Kenji Tomiyoshi ,  Bin Shao ,  Atsushi Matamura ,  Yogesh Sharma ,  Todd Thomas

    Inventor： James W. Zhao ,  Reed W. Adams ,  Kenji Tomiyoshi ,  Bin Shao ,  Atsushi Matamura ,  Yogesh Sharma ,  Todd Thomas

    IPC: H02H9/00

    CPC classification number: H01L27/0285 ,  H01L2924/0002 ,  H01L2924/00

    Abstract: An ESD protection circuit for a switching power converter which includes a high-side switching element connected between a supply voltage and the switching node, and a low-side switching element connected between the switching node and a common node. A current conduction path couples an ESD event that occurs on the switching node to an ESD sense node, and an ESD sensing circuit coupled to the sense node generates a trigger signal when an ESD event is sensed. A first logic gate keeps the high-side switching element off when the trigger signal indicates the sensing of an ESD event, and a second logic gate causes the low-side switching element to turn on when an ESD event is sensed such that the low-side switching element provides a conductive discharge path between the switching node and common node.

    Abstract translation: 一种用于开关电源转换器的ESD保护电路，包括连接在电源电压和开关节点之间的高侧开关元件，以及连接在开关节点和公共节点之间的低侧开关元件。 电流传导路径将在开关节点上发生的ESD事件耦合到ESD感测节点，并且耦合到感测节点的ESD感测电路在感测到ESD事件时产生触发信号。 当触发信号指示ESD事件的感测时，第一逻辑门保持高侧开关元件关闭，并且当检测到ESD事件时，第二逻辑门使低侧开关元件导通， 侧开关元件在开关节点和公共节点之间提供导电放电路径。

    Carotenoid oil suspension with high bioavailability and preparation method thereof
    5.
    发明授权
    Carotenoid oil suspension with high bioavailability and preparation method thereof 有权

    公开(公告)号：US09622497B2

    公开(公告)日：2017-04-18

    申请号：US13997273

    申请日：2011-01-30

    Applicant: Xinde Xu ,  Bin Shao ,  Xuejun Lao

    Inventor： Xinde Xu ,  Bin Shao ,  Xuejun Lao

    IPC: A23D9/007 ,  A61K9/10 ,  A61K31/015 ,  A61K47/44 ,  A23K20/179 ,  A23K20/158

    CPC classification number: A23D9/007 ,  A23K20/158 ,  A23K20/179 ,  A61K9/10 ,  A61K31/015 ,  A61K47/44

    Abstract: A carotenoid oil suspension and preparation method thereof are provided. The method includes the following steps: a) mixing carotenoid with organic solvent, heating the mixture to dissolve the carotenoid sufficiently to obtain carotenoid solution; b) introducing the carotenoid solution obtained in step a) into a vegetable oil solution stirred in high speed by spraying, meanwhile recovering the organic solvent generated during spraying under vacuum condition, then, simultaneously completing recycling and spraying, thereafter, obtaining carotenoid oil suspension; wherein, the carotenoid oil suspension comprises a carotenoid crystal with an average particle size of less than 5 μm. The method is applicable in industrial scale with continuous operation and increased efficiency without additional carotenoid crystal grinding processes, and decreases the degradation of carotenoid during the preparation process of carotenoid oil suspension.

    Benzenesulfonamide compounds and the use thereof
    6.
    发明授权
    Benzenesulfonamide compounds and the use thereof 有权
    苯磺酰胺化合物及其用途

    公开(公告)号：US08937181B2

    公开(公告)日：2015-01-20

    申请号：US12296788

    申请日：2007-04-13

    Applicant: Akira Matsumura ,  Hidenori Mikamiyama ,  Bin Shao ,  Naoki Tsuno ,  Jiangchao Yao

    Inventor： Akira Matsumura ,  Hidenori Mikamiyama ,  Bin Shao ,  Naoki Tsuno ,  Jiangchao Yao

    IPC: C07D211/58 ,  A61K31/4545 ,  A61K31/4468

    CPC classification number: C07D211/58 ,  A61K31/4468 ,  A61K31/4545

    Abstract: The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R1-R3, Z, p and q are defined as set forth in the specification. The invention is also directed to the use compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.

    Abstract translation: 本发明涉及式（I）的氮杂环丁烷基，吡咯烷基，哌啶基和六氢氮杂卟啉化合物及其药学上可接受的盐，前药或溶剂化物，其中R1-R3，Z，p和q如说明书所述定义。 本发明还涉及使用式（I）化合物来治疗，预防或改善对阻断钙通道，特别是N型钙通道的病症。 本发明的化合物特别适用于治疗疼痛。

    Proline analogs as ligands for cannabinoid receptors
    8.
    发明授权
    Proline analogs as ligands for cannabinoid receptors 有权
    脯氨酸类似物作为大麻素受体的配体

    公开(公告)号：US08084612B2

    公开(公告)日：2011-12-27

    申请号：US12350450

    申请日：2009-01-08

    Applicant: Bin Shao ,  Jiangchao Yao

    Inventor： Bin Shao ,  Jiangchao Yao

    IPC: C07D409/12

    CPC classification number: C07D409/12 ,  C07D207/48 ,  C07D403/12 ,  C07D409/14

    Abstract: The invention relates to compounds of Formulae I(a) to XI and pharmaceutically acceptable salts and solvates thereof (Proline Analog Compounds), that are useful, e.g., as ligands for cannabinoid receptors, as compositions comprising a Proline Analog Compound and a pharmaceutically acceptable carrier, in methods of making such Proline Analog Compounds, and in methods for treating or preventing a Condition, such as pain, nausea, vomiting and an eating disorder, comprising administering an effective amount of a Proline Analog Compound to an animal in need thereof.

    Abstract translation: 本发明涉及式I（a）至XI的化合物及其药学上可接受的盐和溶剂合物（脯氨酸类似物化合物），其可用作例如大麻素受体的配体，作为包含脯氨酸类似物化合物和药学上可接受的载体的组合物 ，在制备这种脯氨酸类似物化合物的方法中，以及用于治疗或预防诸如疼痛，恶心，呕吐和进食障碍的病症的方法中，包括向有需要的动物施用有效量的脯氨酸类似物化合物。

    Aryl substituted pyridines and the use thereof
    9.
    发明授权
    Aryl substituted pyridines and the use thereof 有权
    芳基取代的吡啶及其用途

    公开(公告)号：US07943643B2

    公开(公告)日：2011-05-17

    申请号：US12546572

    申请日：2009-08-24

    Applicant: Bin Shao ,  R. Richard Goehring ,  Samuel F. Victory

    Inventor： Bin Shao ,  R. Richard Goehring ,  Samuel F. Victory

    IPC: A61K31/4418 ,  C07D213/26

    CPC classification number: C07D213/81 ,  C07D213/82 ,  Y10T436/145555

    Abstract: This invention relates aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1-R4 are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.

    Abstract translation: 本发明涉及式I的芳基取代的吡啶：或其药学上可接受的盐，前药或溶剂化物，其中Ar和R 1 -R 4被置于说明书中。 本发明还涉及式I化合物用于治疗全身和局部缺血后的神经元损伤，用于治疗或预防神经变性疾病如肌萎缩性侧索硬化（ALS）以及治疗，预防或改善的用途 作为抗惊厥剂，作为抗惊厥剂，作为抗躁狂抑制剂，作为局部麻醉剂，作为抗心律失常药物和用于治疗或预防糖尿病性神经病变。

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