摘要:
The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R1-R3, Z, p and q are defined as set forth in the specification. The invention is also directed to the use compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
摘要:
The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.
摘要:
A rough polysilicon film located on the upper surface of an interlayer film is removed by a CMP process, so that storage nodes and an embedded TEOS film are formed. The embedded TEOS film is removed concurrently with the interlayer film located in a memory cell region by etching. An opening end of a groove, the upper surface of the embedded TEOS film and the upper surface of the interlayer film are arranged on substantially the same plane. In the memory cell region and a peripheral circuit region, a substantially flat interlayer insulation film is obtained. This solves the problems of a step, falling and the like in a semiconductor device including a capacitor element.
摘要:
The invention provides a technology for reducing the direct contact resistance and for reducing the junction leak while maintaining the punch through margin. A semiconductor integrated circuit device is provided which comprises: a substrate; a transistor formed on the substrate, which comprises a source, a drain and a gate which controls a current flowing from said source to said drain; and a contact plug being electrically connected to at least one of the source and drain and made of a conductive material including a dopant. The contact plug is formed of at least a first layer and a second layer. The first layer contacts with one of the source and drain and is made of said material including the dopant of a first concentration. The second layer is formed of a layer of said material including the dopant of a second concentration, which is lower than the second concentration.
摘要:
Disclosed is a process for plating a metallic deposit between functional pattern lines on a substrate, comprising (a) forming a cured film containing a catalyst for electroless plating on the substrate, (b) forming functional pattern lines on said cured film, and (c) conducting electroless plating.
摘要:
The present invention provides a process for forming a solder mask on an electric circuit board without any defects. The process comprises forming an electric circuit on a substrate, coating a negative type photosensitive solder resist on the obtained electric circuit board, and then exposing to light through a negative film followed by developing, characterized in that the negative type photosensitive solder resist is electrodepositable and said coating of the solder resist is conducted by electrocoating the resist on an electroconductive transfer substrate which is different from the electric circuit board and then transferring the coated film onto the electric circuit board.
摘要:
A driving assurance system for an automotive vehicle includes a steering detector which generates an electrical pulse in response to each angular movement of the steering wheel exceeding an arcuate extent less than 10.degree.. A monostable multivibrator is connected to the steering detector to generate an output pulse in response to the first one of such pulses generated by a single steering operation so that the output from the miltivibrator may represent a single steering operation. The output from the multivibrator is counted for a predetermined period to determine the state of the driver to operate a warning signal when he becomes incapacitated.
摘要:
A driving assurance system for an automotive vehicle includes a steering detector which generates an electrical pulse in response to each angular movement of the steering wheel exceeding an arcuate extent less than 10.degree.. A monostable multivibrator is connected to the steering detector to generate an output pulse in response to the first one of such pulses generated by a single steering operation so that the output from the multivibrator may represent a single steering operation. The output from the multivibrator is counted for a predetermined period to determine the state of the driver to operate a warning signal when he becomes incapacitated.
摘要:
The object of the present invention is to provide novel compounds having ACC2 inhibiting activity. In addition, the object of the present invention is to provide a pharmaceutical composition comprising the compound.A compound of formula (I′): wherein R1 is substituted or unsubstituted aryl etc., R2 is each independently hydrogen, substituted or unsubstituted alkyl etc., R3 is each independently hydrogen, substituted or unsubstituted alkyl etc., n is an integer from 0 to 3, R12 is hydrogen, substituted or unsubstituted alkyl etc., Ring A is aromatic carbocycle or aromatic heterocycle, R9 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl etc., m is an integer from 0 to 4, R4 and R5 is each independently hydrogen, substituted or unsubstituted alkyl etc., R6 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl etc., R13 is hydrogen, substituted or unsubstituted alkyl etc., X5 is bond etc., R7 is hydrogen or substituted or unsubstituted alkyl, R8 is substituted or unsubstituted alkylcarbonyl, substituted or unsubstituted alkenylcarbonyl etc.
摘要:
The invention relates to acrylamide compounds of Formula I mentioned below.The invention is also directed to the use compounds of Formula I to treat or prevent a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.