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公开(公告)号:US20180299475A1
公开(公告)日:2018-10-18
申请号:US15943362
申请日:2018-04-02
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Yochanan Uri , Igor KOCHETKOV , Shai AHARON , Itay BARAK , Uri ISSMAN
Abstract: Fraction collector dispensers and methods of using such dispensers are provided. In one embodiment, the dispenser includes an inlet for receiving liquid from a liquid source, wherein the inlet is in fluid communication with an outlet from which liquid is dispensed into a receptacle; and a reservoir in fluid communication with a flow path between the inlet and outlet, wherein the reservoir comprises trapped air therein and is configured to receive liquid during movement of the dispenser between receptacles or during movement of receptacles between dispense positions, wherein the dispenser is moveable between a first receptacle and a second receptacle or the receptacles are moveable between dispense positions.
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公开(公告)号:US20170016829A1
公开(公告)日:2017-01-19
申请号:US15211728
申请日:2016-07-15
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Steve SWIHART , Evan THRUSH , Yochanan URI , Boaz RAN , Itay BARAK , Kevin MCDONAL
CPC classification number: G02B6/08 , G01N21/6454 , G01N27/44721 , G01N2021/6484 , G02B5/22 , G02B5/28
Abstract: Devices, systems, methods, and kits for contact imaging are provided. A contact imaging device includes an imaging sensor, a fixed fiber faceplate mechanically coupled to the imaging sensor, and an optical filtering layer mechanically coupled to the fixed fiber faceplate. The optical filtering layer can include an interference filter, an absorptive filter, and/or a removable fiber faceplate. The contact imaging device can be used to image fluorescent samples by filtering out excitation light on the basis of wavelength and/or angle of incidence.
Abstract translation: 提供了用于接触成像的设备,系统,方法和套件。 接触成像装置包括成像传感器,机械耦合到成像传感器的固定光纤面板以及机械耦合到固定光纤面板的光学滤光层。 光学滤光层可以包括干涉滤光器,吸收滤光器和/或可移除的光纤面板。 接触成像装置可用于通过基于波长和/或入射角滤除激发光来对荧光样品进行成像。
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公开(公告)号:US20190186987A1
公开(公告)日:2019-06-20
申请号:US16219715
申请日:2018-12-13
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Itay BARAK
CPC classification number: G01J1/0403 , G01J1/0407 , G01N21/6428 , G01N21/76 , G01N33/5302 , G01N2021/6439
Abstract: A combination imaging system includes a housing having a base and a lid, the lid having a closed position against the base and having an open position. The imaging device further includes a contact area image sensor. The lid shields the contact area image sensor from ambient light when the lid is in the closed position. The imaging device also includes a camera. The camera includes a lens, and the field of view of the camera encompasses at least a portion of an imaging area of the contact area image sensor when the lid is in the open position. The device may be especially useful for capturing a chemiluminescent image of an electrophoretic assay result, and capturing a colorimetric image of the same result, so that non-chemiluminescent protein standards may be located with respect to chemiluminescent analytes of interest.
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公开(公告)号:US20170366768A1
公开(公告)日:2017-12-21
申请号:US15675494
申请日:2017-08-11
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Boaz RAN , Steve SWIHART , Evan THRUSH , Itay BARAK
Abstract: In one application, an imaging device includes an image sensor having an array of pixels, and a mask coupled with the image sensor. The mask is configured to darken a plurality of isolated pixels or groups of pixels interspersed within the array of pixels. The imaging device also includes a processor coupled with the image sensor and configured to receive image data from the image sensor, and determine a dark current fixed pattern noise based on the image data received from the plurality of darkened pixels or groups of pixels.
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公开(公告)号:US20210302229A1
公开(公告)日:2021-09-30
申请号:US17346873
申请日:2021-06-14
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Itay BARAK
Abstract: A combination imaging system includes a housing having a base and a lid, the lid having a closed position against the base and having an open position. The imaging device further includes a contact area image sensor. The lid shields the contact area image sensor from ambient light when the lid is in the closed position. The imaging device also includes a camera. The camera includes a lens, and the field of view of the camera encompasses at least a portion of an imaging area of the contact area image sensor when the lid is in the open position. The device may be especially useful for capturing a chemiluminescent image of an electrophoretic assay result, and capturing a colorimetric image of the same result, so that non-chemiluminescent protein standards may be located with respect to chemiluminescent analytes of interest.
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公开(公告)号:US20160356712A1
公开(公告)日:2016-12-08
申请号:US15176181
申请日:2016-06-08
Applicant: Bio-Rad Laboratories Inc.
Inventor: Boaz RAN , Itay BARAK
IPC: G01N21/552
CPC classification number: G01N21/553 , G02B3/005 , G02B5/008
Abstract: A system for measuring an evanescent wave phenomenon at total internal reflection, the system comprising: a) a sensing surface comprising a plurality of areas of interest; b) an illumination sub-system comprising a light source, which illuminates each area of interest on the sensing surface over a range of angles of incidence; c) a detector which responds differently to an intensity of light received by it at different locations; and d) projection optics comprising primary optics and a plurality of secondary elements, the primary optics projecting an image of the illuminated sensing surface onto the secondary elements, which project their received light onto the detector in such a way that it is possible to determine, from the response of the detector, how much light is reflected from each area of interest, as a function of angle of incidence over the range of angles for that area.
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