-
公开(公告)号:US07016470B2
公开(公告)日:2006-03-21
申请号:US10812339
申请日:2004-03-29
CPC分类号: H01S3/083 , H01S3/1109 , H05G2/00
摘要: The invention provides a system for generating X-rays via the process of inverse Compton scattering. The system includes a high repetition rate laser adapted to direct high-energy optical pulses in a first direction in a laser cavity and a source of pulsed electron beam adapted to direct electron beam in a second direction opposite to the first direction in the laser cavity. The electron beam interacts with photons in the optical pulses in the laser cavity to produce X-rays in the second direction.
摘要翻译: 本发明提供一种通过反康普顿散射过程产生X射线的系统。 该系统包括高激光器,其适于在激光腔中沿第一方向引导高能光脉冲,以及适于在与激光腔中的第一方向相反的第二方向上引导电子束的脉冲电子束源。 电子束与激光腔中的光脉冲中的光子相互作用以在第二方向产生X射线。
-
公开(公告)号:US06710912B1
公开(公告)日:2004-03-23
申请号:US10326124
申请日:2002-12-23
IPC分类号: G02F1355
CPC分类号: G02F1/3775 , G02F2001/3548 , G02F2202/32
摘要: A technique for achieving quasi phase matching in a photonic band gap structure comprising a first material and a second material is disclosed. In one particular exemplary embodiment, the technique may be realized by calculating a coherence length of an optical interaction of interest involving at least a first frequency and a second frequency; calculating a first lattice constant of the first material to achieve a predetermined first group velocity for a fundamental optical frequency; calculating a second lattice constant of the second material so that a second group velocity of a second optical frequency is substantially the same as the first group velocity associated with the fundamental optical frequency of the first material; determining a photonic band gap arrangement for achieving quasi phase matching in the photonic band gap structure; and implementing the first lattice constant of the first material and the second lattice constant of the second material in accordance with the photonic band gap arrangement to achieve quasi phase matching in the photonic band gap structure.
摘要翻译: 公开了一种在包括第一材料和第二材料的光子带隙结构中实现准相位匹配的技术。 在一个特定示例性实施例中,可以通过计算涉及至少第一频率和第二频率的感兴趣的光学相互作用的相干长度来实现该技术; 计算第一材料的第一晶格常数以实现基本光频率的预定的第一组速度; 计算第二材料的第二晶格常数,使得第二光频率的第二组速度与与第一材料的基本光频率相关联的第一组速度基本相同; 确定用于实现光子带隙结构中的准相位匹配的光子带隙布置; 并且根据光子带隙布置实现第一材料的第一晶格常数和第二材料的第二晶格常数,以实现光子带隙结构中的准相位匹配。
-
公开(公告)号:US08964183B2
公开(公告)日:2015-02-24
申请号:US13485026
申请日:2012-05-31
CPC分类号: G01N21/59 , G01N21/4738 , G01N21/6408 , G01N21/6458
摘要: A screening module configured to screen at least a portion of a biological sample disposed on an analysis surface is provided. The screening module comprises a laser source a scanning unit comprising one or more scanning devices, wherein the scanning devices are configured to rotate in an oscillatory scanning motion about an axis of rotation to scan the analysis surface in at least one direction, wherein the scanning unit is physically coupled to the laser source, and a detection unit comprising one or more detection devices.
摘要翻译: 提供了一种被配置为筛选设置在分析表面上的生物样品的至少一部分的筛选模块。 筛选模块包括激光源,扫描单元包括一个或多个扫描装置,其中扫描装置被配置为以围绕旋转轴的振荡扫描运动旋转,以在至少一个方向上扫描分析表面,其中扫描单元 物理耦合到激光源,以及检测单元,其包括一个或多个检测装置。
-
公开(公告)号:US20130321814A1
公开(公告)日:2013-12-05
申请号:US13485026
申请日:2012-05-31
CPC分类号: G01N21/59 , G01N21/4738 , G01N21/6408 , G01N21/6458
摘要: A screening module configured to screen at least a portion of a biological sample disposed on an analysis surface is provided. The screening module comprises a laser source a scanning unit comprising one or more scanning devices, wherein the scanning devices are configured to rotate in an oscillatory scanning motion about an axis of rotation to scan the analysis surface in at least one direction, wherein the scanning unit is physically coupled to the laser source, and a detection unit comprising one or more detection devices.
摘要翻译: 提供了一种被配置为筛选设置在分析表面上的生物样品的至少一部分的筛选模块。 筛选模块包括激光源,扫描单元包括一个或多个扫描装置,其中扫描装置被配置为以围绕旋转轴的振荡扫描运动旋转,以在至少一个方向上扫描分析表面,其中扫描单元 物理耦合到激光源,以及检测单元,其包括一个或多个检测装置。
-
公开(公告)号:US6142019A
公开(公告)日:2000-11-07
申请号:US235915
申请日:1999-01-25
CPC分类号: G10K11/36 , G01N29/069 , G01N29/2418 , G01V1/284 , G01N2291/0423
摘要: A method for determining surface acoustic wave ray paths for an object. The method includes obtaining a representation of the object. A plurality of geodesics from a point on the object are determined and a plurality of surface acoustic wave ray paths are defined in response to the plurality of geodesics. The acoustic wave ray paths are used to determine a plurality of equally spaced surface acoustic wave fronts. In one application the surface acoustic wave fronts may then be used in a synthetic aperture focusing technique to obtain an image of the object.
摘要翻译: 一种用于确定物体的表面声波路径的方法。 该方法包括获得对象的表示。 确定来自物体上的点的多个测地线,并且响应于多个测地线来定义多个表面声波射线路径。 声波射线路径用于确定多个相等间隔的声表面波阵面。 在一个应用中,表面声波前沿然后可以用于合成孔径聚焦技术中以获得物体的图像。
-
6.
公开(公告)号:US07310408B2
公开(公告)日:2007-12-18
申请号:US11096488
申请日:2005-03-31
申请人: Robert John Filkins , John Scott Price , Brian Lee Lawrence , Matthew Christian Nielsen , Joseph John Manak , Bruce Matthew Dunham
发明人: Robert John Filkins , John Scott Price , Brian Lee Lawrence , Matthew Christian Nielsen , Joseph John Manak , Bruce Matthew Dunham
IPC分类号: H05G2/00
CPC分类号: H05G2/00
摘要: A system for generating a tunable X-ray pulse comprises a first electron beam source configured to direct a first electron pulse of predetermined energy and pulse length towards a first interaction zone, a laser beam source configured to direct a first photon pulse of predetermined energy and pulse length towards the first interaction zone to interact with the first electron pulse. The first interaction produces a substantially monochromatic second photon pulse of higher photon energy directed towards a second interaction zone, and a second electron beam source configured to direct a second electron pulse of predetermined energy and pulse length towards the second interaction zone so that the second interaction produces an X-ray pulse of predetermined energy and pulse length in a cascaded inverse Compton scattering (ICS) configuration.
摘要翻译: 一种用于产生可调谐X射线脉冲的系统包括:第一电子束源,被配置为将预定能量和脉冲长度的第一电子脉冲引导到第一相互作用区域,激光束源被配置为引导预定能量的第一光子脉冲;以及 脉冲长度朝向第一相互作用区域与第一电子脉冲相互作用。 所述第一相互作用产生指向第二相互作用区的较高光子能量的基本上单色的第二光子脉冲,以及被配置成将预定能量和脉冲长度的第二电子脉冲引向所述第二相互作用区域的第二电子束源, 在级联反康普顿散射(ICS)配置中产生预定能量和脉冲长度的X射线脉冲。
-
公开(公告)号:US07411991B2
公开(公告)日:2008-08-12
申请号:US10815907
申请日:2004-03-31
IPC分类号: H01S3/081
CPC分类号: H01S3/09415 , G11B7/0065 , G11B7/127 , H01S3/0815 , H01S3/1062 , H01S3/109 , H01S3/1623 , H01S3/1631
摘要: Embodiments of methods, apparatuses, devices, and/or systems for a tunable laser are described. An apparatus includes: a tunable laser cavity including at least three mirrors, at least one filter and a plurality of crystals, wherein the three mirrors are substantially arranged in a lambda configuration, the filter includes a birefringent filter and an etalon, at least one of the crystals comprises a Cologuiriite crystal, and at least one other of the crystals comprises a nonlinear crystal, wherein the mirrors, the filter, and the plurality are configured for providing electromagnetic radiation of an approximately single frequency; and at least one electromagnetic radiation source being coupled to the laser cavity, wherein the electromagnetic radiation source is capable of providing electromagnetic radiation having an approximately particular wavelength to the laser cavity.
摘要翻译: 描述了可调谐激光器的方法,装置,装置和/或系统的实施例。 一种装置包括:可调激光腔,包括至少三个反射镜,至少一个滤光器和多个晶体,其中三个反射镜基本上以λ构型布置,滤光器包括双折射滤光器和标准具,至少一个 所述晶体包括Cologuiriite晶体,并且所述晶体中的至少一个晶体包括非线性晶体,其中所述反射镜,所述滤光器和所述多个晶体被配置用于提供近似单个频率的电磁辐射; 以及耦合到所述激光腔的至少一个电磁辐射源,其中所述电磁辐射源能够向所述激光腔提供具有近似特定波长的电磁辐射。
-
公开(公告)号:US07123393B2
公开(公告)日:2006-10-17
申请号:US10952513
申请日:2004-09-28
CPC分类号: G11B7/0065 , G03H1/28 , G03H2001/266 , G03H2222/13 , G11B7/00772 , G11B7/127 , G11B7/128
摘要: A wavelength multiplexed holographic system includes a wavelength tunable blue-violet laser and a controller for wavelength multiplexing. A method of holographic data recording includes providing a holographic medium, providing a tunable blue-violet laser for wavelength multiplexing, and tuning the laser wavelength to record a hologram at a set wavelength and recording holographic data at the set wavelength on the holographic medium. A method for retrieving holographic data includes providing a holographic medium, providing at least one tunable blue-violet laser, tuning the blue-violet laser to a set wavelength, and retrieving holographic data at the set wavelength.
摘要翻译: 波长复用全息系统包括波长可调蓝紫色激光器和用于波长复用的控制器。 一种全息数据记录方法,包括提供全息介质,提供用于波长多路复用的可调蓝紫色激光,并调谐激光波长以记录设定波长的全息图,并在全息介质上记录设定波长的全息数据。 用于检索全息数据的方法包括提供全息介质,提供至少一个可调蓝紫色激光,将蓝紫色激光调谐到设定波长,以及检索设定波长的全息数据。
-
公开(公告)号:US08900529B2
公开(公告)日:2014-12-02
申请号:US13458092
申请日:2012-04-27
IPC分类号: B01L99/00
CPC分类号: B32B37/0076 , B01L3/5027 , B01L3/502707 , B01L9/527 , B01L2200/027 , B01L2200/0689 , B01L2300/0816 , B01L2300/0822 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2400/0655 , B32B37/182 , B32B38/0008 , B32B2535/00 , Y10T156/10 , Y10T156/1056 , Y10T156/108
摘要: A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. Methods for fabricating the subassembly and assembled flow cell are also provided. The method includes the steps of adhering a gasket layer to a substrate layer, wherein the gasket layer may contain enclosed features and adhering an adherent layer to the gasket layer. The subassembly may be sealed against a solid support to form a flow cell.
摘要翻译: 描述了可以组装成具有在主底物外部的流体连接的流动池的微流体流动池子组件,用于封装样品以允许随后控制的试剂递送到样品中,例如原位复合生物标记染色和分析 。 还提供了用于制造子组件和组装流动池的方法。 该方法包括以下步骤:将衬垫层粘附到衬底层,其中衬垫层可以包含封闭特征并将粘附层粘附到衬垫层。 子组件可以密封在固体支撑件上以形成流动池。
-
公开(公告)号:US20120231967A1
公开(公告)日:2012-09-13
申请号:US13457531
申请日:2012-04-27
申请人: Anup Sood , Michael Christopher Montalto , Michael Gerdes , Maximilian Lewis Seel , Robert John Filkins
发明人: Anup Sood , Michael Christopher Montalto , Michael Gerdes , Maximilian Lewis Seel , Robert John Filkins
IPC分类号: C40B30/04
CPC分类号: G01N33/53 , C12Q1/68 , G01N33/542 , G01N33/582 , Y10T436/143333
摘要: Methods for detecting multiple targets in a biological sample are provided. The methods includes contacting the sample with a first probe; physically binding the first probe to a first target; observing a first signal from the first probe; applying a chemical agent to modify the first signal; contacting the sample with a second probe; physically binding the second probe to a second target; and observing a second signal from the second probe. The methods disclosed herein also provide for multiple iterations of binding, observing, signal modification for deriving information about multiple targets in a single sample. An associated kit and device are also provided.
摘要翻译: 提供了用于检测生物样品中多个靶的方法。 所述方法包括使样品与第一探针接触; 将第一探针物理地绑定到第一靶; 观察来自第一探针的第一信号; 施用化学试剂来修饰第一信号; 使样品与第二探针接触; 将第二探针物理地绑定到第二靶上; 并观察来自第二探测器的第二信号。 本文公开的方法还提供绑定,观察,信号修改的多次迭代,用于导出关于单个样本中的多个目标的信息。 还提供了相关的套件和设备。
-
-
-
-
-
-
-
-
-