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公开(公告)号：US20120085262A1
公开(公告)日：2012-04-12
申请号：US13217868
申请日：2011-08-25
申请人： Evgueni Klimov , Burghard Liebmann , Thomas Subkowski , Martin Möller , Doris Klee , Artem Davidenko , Wiebke Voigt , Gunter Scharfenberger
发明人： Evgueni Klimov , Burghard Liebmann , Thomas Subkowski , Martin Möller , Doris Klee , Artem Davidenko , Wiebke Voigt , Gunter Scharfenberger
IPC分类号： C09D189/00 , B29C47/00
CPC分类号： C09D189/00 , B29C48/05 , B29C48/142 , C08L89/00 , Y10T442/681
摘要： The present invention concerns stable aqueous protein dispersions comprising in an aqueous phase at least one self-assembling protein in dispersed form and also at least one specific dispersant for the self-assembling protein; processes for producing such stable aqueous dispersions; processes for electrospinning self-assembling proteins using such stable aqueous dispersions; processes for producing fibrous sheet bodies or fibers from such aqueous dispersions; the use of such aqueous dispersions for coating surfaces; the use of the materials produced by electrospinning in the manufacture of medical devices, hygiene articles and textiles; and also fibrous or fibrous sheet bodies produced by an electrospinning process of the present invention.
摘要翻译： 本发明涉及稳定的水性蛋白质分散体，其在水相中包含至少一种分散形式的自组装蛋白质，以及至少一种用于自组装蛋白质的特定分散剂; 制备这种稳定的水性分散体的方法; 使用这种稳定的水分散体静电纺丝自组装蛋白的方法; 从这种水性分散体生产纤维片体或纤维的方法; 使用这种水性分散体涂覆表面; 使用通过静电纺丝制造的材料制造医疗器械，卫生用品和纺织品; 以及通过本发明的静电纺丝方法制造的纤维或纤维片体。
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2.发明申请公开(公告)号：US20110129510A1
公开(公告)日：2011-06-02
申请号：US13058033
申请日：2009-08-07
申请人： Burghard Liebmann , Evgueni Klimov
发明人： Burghard Liebmann , Evgueni Klimov
IPC分类号： A61K9/70 , A61K47/32 , A61K47/30 , A61K8/72 , A01N25/00 , A61K8/02 , A01P3/00 , A23P1/10 , A23L1/308 , A23K1/16
CPC分类号： A61K9/70 , A61K31/4174 , A61K31/4196 , A61K47/32 , A61K47/42 , C07K14/43518
摘要： The invention relates to a fibrous surface structure containing active ingredients with an adjustable active ingredient release profile, comprising a fibrous, polymeric, soluble and/or degradable active ingredient substrate and at least one active ingredient that is associated with the substrate and can be released by the fibrous surface structure; to formulations containing active ingredients, comprising such fibrous surface structures; to the use of fibrous surface structures containing active ingredients according to the invention for producing formulations containing active ingredients; and to a method for producing fibrous surface structures according to the invention.
摘要翻译： 本发明涉及含有具有可调节活性成分释放曲线的活性成分的纤维表面结构，其包含纤维状，聚合型，可溶性和/或可降解的活性成分底物和至少一种与底物相关的活性成分，并可通过 纤维表面结构; 包含含有活性成分的制剂，包含这种纤维表面结构; 涉及使用含有根据本发明的活性成分的纤维表面结构来制备含有活性成分的制剂; 以及根据本发明的用于生产纤维表面结构的方法。
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3.发明申请公开(公告)号：US20110136669A1
公开(公告)日：2011-06-09
申请号：US13058141
申请日：2009-08-07
申请人： Burghard Liebmann , Evgueni Klimov
发明人： Burghard Liebmann , Evgueni Klimov
CPC分类号： A01N25/10 , A61F13/00012 , A61F2013/00221 , A61F2013/00731 , A61K8/64 , A61K9/2063 , A61K9/70 , A61K31/00 , A61K47/42 , A61L15/32 , A61L15/44 , A61L2300/216 , A61L2300/604 , A61Q17/04 , C07K14/43586
摘要： The invention relates to continuous fiber layers comprising an active substance on the basis of bio-polymers, comprising a fibrous, bio-polymer active substance carrier, and at least one active substance associated with the carrier and releasable from the continuous fiber layer; to formulations comprising an active substance, said formulations comprising such continuous fiber layers; to the use of continuous fiber layers comprising an active substance for the production of formulations comprising an active substance; and to a method for the production of continuous fiber layers comprising an active substance. The invention further relates to corresponding continuous fiber layers comprising an active substance and to the use thereof for the production of wound treatment and hygiene products, and to the respectively produced wound treatment and hygiene products.
摘要翻译： 本发明涉及包含基于生物聚合物的活性物质的连续纤维层，其包含纤维状生物聚合物活性物质载体和与载体相关联并可从连续纤维层释放的至少一种活性物质; 包含活性物质的制剂，所述制剂包含这种连续纤维层; 涉及使用包含活性物质的连续纤维层来制备包含活性物质的制剂; 以及用于生产包含活性物质的连续纤维层的方法。 本发明还涉及包含活性物质的相应的连续纤维层及其用于生产伤口处理和卫生产品的用途以及分别生产的伤口处理和卫生产品。
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公开(公告)号：US20100216189A1
公开(公告)日：2010-08-26
申请号：US12664902
申请日：2008-06-16
申请人： Burghard Liebmann , Marcus Fehr , Daniel Hümmerich
发明人： Burghard Liebmann , Marcus Fehr , Daniel Hümmerich
CPC分类号： C07K14/43581 , A23K20/147 , A61K8/64 , A61Q19/00 , C07K14/43518 , D06M15/15 , D21H17/22 , D21H19/50
摘要： A repetitive protein having repetition units comprising the consensus sequence (I) X1 X2 X3 X4 S X5 X6 Y G wherein X1 is G, Y, A or N X2 is G, L, Q X3 is R, K, T or P X4 is P, A, T or S X5 is D, T or S X6 is S, Q or T, and the consensus sequence (II) Z1 Z2 (Z3A)nZ4 Z5 Z6 wherein Z1 is S, Q, N, T or G Z2 is not an amino acid or A Z3 is A or G Z4 is not an amino acid, A or S Z5 is G, S, Q, N or T Z6 is G, P, S, Q, N or T n is a natural whole number, wherein 2≦n≦12.
摘要翻译： 具有包含共有序列（I）X1 X2 X3 X4 S X5 X6 Y G的重复单元的重复蛋白质，其中X1为G，Y，A或N X2为G，L，Q X3为R，K，T或P X4为 P，A，T或S X5为D，T或S X6为S，Q或T，共有序列（II）Z1 Z2（Z3A）nZ4 Z5 Z6其中Z1为S，Q，N，T或GZ2 不是氨基酸或A Z3是A或G Z4不是氨基酸，A或S Z5是G，S，Q，N或T Z6是G，P，S，Q，N或T n是天然的 整数，其中2＆nlE; n＆nlE; 12。
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公开(公告)号：US20090098076A1
公开(公告)日：2009-04-16
申请号：US12094833
申请日：2006-11-15
申请人： Heiko Barg , Burghard Liebmann , Martin Volkert , Arne Ptock , Heike Reents
发明人： Heiko Barg , Burghard Liebmann , Martin Volkert , Arne Ptock , Heike Reents
CPC分类号： C07D207/448 , A61K8/64 , A61K47/6435 , A61K2800/57 , A61K2800/94 , A61Q1/02 , A61Q3/00 , A61Q5/00 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q17/04 , A61Q19/00 , A61Q19/002 , A61Q19/004 , A61Q19/04 , A61Q19/10 , C07D207/452
摘要： The invention relates to a method of producing keratin-binding effector molecules, and to intermediates and end-products of the method according to the invention and to the use of the keratin-binding effector molecules produced according to the invention in dermocosmetics. In addition, the invention relates to a method of applying dermocosmetically active ingredients to skin and/or hair and to a method of increasing the residence time of an active ingredient on skin and hair.
摘要翻译： 本发明涉及一种产生角蛋白结合效应分子的方法，以及根据本发明的方法的中间体和终产物以及根据本发明生产的角蛋白结合效应分子在皮肤科药物中的用途。 此外，本发明涉及一种将皮肤发光活性成分施用于皮肤和/或毛发的方法以及增加活性成分在皮肤和毛发上的停留时间的方法。
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公开(公告)号：US20130029846A1
公开(公告)日：2013-01-31
申请号：US13638090
申请日：2011-03-28
申请人： Joachim Rheinheimer , Christian Pilger , Stefan Redlich , Doris Kremzow , Claudia Rosenbaum , Burghard Liebmann , Wassilios Grammenos
发明人： Joachim Rheinheimer , Christian Pilger , Stefan Redlich , Doris Kremzow , Claudia Rosenbaum , Burghard Liebmann , Wassilios Grammenos
IPC分类号： A01N43/52 , C07D235/04 , C07D209/14 , A01N43/38 , A01P3/00 , C07D249/18 , A01N43/56 , C07D231/56 , A61K31/343 , C07D307/87 , A01N25/26 , A01N43/647
CPC分类号： C07D209/40 , C07D235/30 , C07D249/18 , C07D307/82
摘要： The present invention relates to the use of bicyclic amidine compounds of formula I as defined in the description, and the N-oxides, and salts thereof for combating harmful fungi, and also to compositions and seed comprising at least one such compound. The invention also relates to novel bicyclic amidines and processes and intermediates for preparing these compounds.
摘要翻译： 本发明涉及描述中所定义的式I的双环脒化合物及其N-氧化物及其盐用于防治有害真菌，以及包含至少一种这样的化合物的组合物和种子。 本发明还涉及用于制备这些化合物的新型双环脒和方法和中间体。
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公开(公告)号：US20120088268A1
公开(公告)日：2012-04-12
申请号：US13375559
申请日：2010-06-02
CPC分类号： C07K14/4723 , C07K2319/00 , C07K2319/50 , C12N15/62 , C12P21/06
摘要： The present invention relates to repetitive self-assembling precursor proteins, nucleic acid sequences and expression constructs encoding the same, and to methods for recombinant production of peptides using such precursor proteins.
摘要翻译： 本发明涉及重复自组装前体蛋白，核酸序列和编码其的表达构建体，以及使用这种前体蛋白重组生成肽的方法。
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8.发明申请METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS 审中-公开将KERATIN结合聚合物与支持羧基或磺酸基团的效应子分子联合的方法公开(公告)号：US20090156485A1
公开(公告)日：2009-06-18
申请号：US12094803
申请日：2006-11-15
申请人： Heiko Barg , Burghard Liebmann , Martin Volkert , Arne Ptock , Heike Reents
发明人： Heiko Barg , Burghard Liebmann , Martin Volkert , Arne Ptock , Heike Reents
IPC分类号： A61K38/00 , C07K1/00 , C07K14/00 , C07D207/40
CPC分类号： A61Q17/04 , A61K8/64 , A61K47/62 , A61K47/6843 , A61K2800/57 , A61K2800/94 , A61Q1/02 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q17/00 , A61Q19/00 , A61Q19/002 , A61Q19/004 , A61Q19/04 , A61Q19/10
摘要： The invention relates to a method of producing keratin-binding effector molecules and to intermediates and end-products of the method according to the invention and to the use of the keratin-binding effector molecules produced according to the invention in dermocosmetics.
摘要翻译： 本发明涉及一种生产角蛋白结合效应分子的方法，以及根据本发明的方法的中间体和终产物以及根据本发明生产的角蛋白结合效应物分子在皮肤科药中的用途。
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公开(公告)号：US09481719B2
公开(公告)日：2016-11-01
申请号：US13375559
申请日：2010-06-02
CPC分类号： C07K14/4723 , C07K2319/00 , C07K2319/50 , C12N15/62 , C12P21/06
摘要： The present invention relates to repetitive self-assembling precursor proteins, nucleic acid sequences and expression constructs encoding the same, and to methods for recombinant production of peptides using such precursor proteins.
摘要翻译： 本发明涉及重复自组装前体蛋白，核酸序列和编码其的表达构建体，以及使用这种前体蛋白重组生成肽的方法。
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公开(公告)号：US08765688B2
公开(公告)日：2014-07-01
申请号：US12809102
申请日：2008-12-19
CPC分类号： A61Q5/006 , A61K8/64 , A61Q1/02 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q17/04 , A61Q19/00 , A61Q19/002 , A61Q19/04 , A61Q19/10 , C08L89/00 , Y10T436/143333
摘要： The present invention relates to the use of special peptides in composition which can be used in particular in hair and skin cosmetics, and to such peptide-containing compositions. In particular, the present invention relates to the use of such peptides as active ingredient for inhibition or treatment of dandruff which does not accumulate in the body or in the environment. Furthermore, the invention relates to the production of such compositions, to the peptides used themselves, to their production and to coding nucleotide sequences for such peptides, to dispensing systems for such peptides and to screening methods for identifying suitable further peptides.
摘要翻译： 本发明涉及可用于特别是头发和皮肤化妆品的组合物中的特殊肽以及这种含肽组合物的用途。 特别地，本发明涉及这种肽作为活性成分用于抑制或治疗不积累在体内或环境中的头皮屑的用途。 此外，本发明涉及这样的组合物的生产，本身使用的肽，其生产和编码这些肽的核苷酸序列，分配用于这些肽的系统以及筛选用于鉴定合适的另外的肽的方法。
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