摘要:
Disclosed is a pharmaceutical composition for treating and preventing cancer, comprising a Cinnamoni Cortex extract and a Zizyphi Fructus extract. The pharmaceutical composition has effects of inducing apoptosis of cancer cells and inhibiting metastasis of cancer cells, as well as having a synergistic effect in inhibiting the growth of cancer cells compared to the separate use of the two extracts. Also, because the two extracts are extracted from natural origins, the pharmaceutical composition has no toxicity and is thus able to be used as a safe anticancer agent having excellent therapeutic efficacy. Further, the pharmaceutical composition is capable of being used as a functional food for preventing and treating cancer.
摘要:
Disclosed are novel indazole derivatives represented by the following Chemical Formula 1 or pharmaceutically acceptable salts, hydrates or solvates thereof, and pharmaceutical compositions for the prevention or treatment of proliferative diseases, containing the same as an active ingredient. Having potent inhibitory effect against protein kinase, such as b-raf, KDR, Fms, Tie2, SAPK2a and Ret, inducing diseases caused by abnormal cell proliferation, the novel indazole derivatives can be used for the prevention or treatment of diseases caused by abnormal cell proliferation.
摘要:
Disclosed are novel indazole derivatives represented by the following Chemical Formula 1 or pharmaceutically acceptable salts, hydrates or solvates thereof, and pharmaceutical compositions for the prevention or treatment of proliferative diseases, containing the same as an active ingredient. Having potent inhibitory effect against protein kinase, such as b-raf, KDR, Fms, Tie2, SAPK2a and Ret, inducing diseases caused by abnormal cell proliferation, the novel indazole derivatives can be used for the prevention or treatment of diseases caused by abnormal cell proliferation.
摘要:
The present invention is related to novel use of 2-oxo-heterocyclic compounds having anticancer activity and the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the cancer disease comprising lung cancer, bone cancer, pancreatic cancer, skin cancer, cancer of the head and neck, cutaneous or intraocular melanoma, uterine cancer, ovarian cancer, rectal cancer or cancer of the anal region, stomach cancer, colon cancer, breast cancer, gynecologic tumors, Hodgkin's disease, cancer of the esophagus, cancer of the small intestine, cancer of the endocrine system, sarcomas of soft tissues, cancer of the urethra, cancer of the penis, prostate cancer, chronic or acute leukemia, solid tumors of childhood, lymphocytic lymphonas, cancer of the bladder, cancer of the kidney or ureter, or neoplasms of the central nervous system, therefore, it can be used as the therapeutics for treating and preventing cancer diseases.
摘要:
A substituted thieno pyrimidine compound of Formula 1, pharmaceutically acceptable salts and a pharmaceutical composition thereof is provided. The compound of Formula 1 exhibits superior inhibition activity against various protein kinases involved in growth factor signal transduction. The compound of Formula 1 and its compositions are useful for the prevention and treatment of diseases caused by abnormal cell growth including cancer.
摘要:
A power supply apparatus for an electric bicycle is disclosed. The apparatus may include i) a battery pack and ii) a keybox connected to the battery pack and controlling on/off operations of the power supply apparatus. The keybox may further include i) a key set configured to receive a key cylinder that is moveable according to the rotation of a key inserted into the key box, ii) a contact terminal that includes a first plurality of sub-terminals, iii) a terminal base including at least one second sub-terminal connectable to and detachable from at least one of the first sub-terminals and iv) a keybox case configured to receive the key set, the contact terminal, and the terminal base. The terminal base may have a plate shape with a polygonal periphery surface at least part of which contacts an inner portion of the keybox case.
摘要:
The present invention relates to a thieno[3,2-d]pyrimidine derivative of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, which has an excellent inhibitory activity on protein kinases, and a pharmaceutical composition comprising the same is effective in preventing or treating abnormal cell growth diseases.
摘要:
The present invention relates to a novel bicyclic heteroaryl derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof, and a solvate thereof having an improved inhibitory activity for protein kinases, and a pharmaceutical composition for preventing or treating an abnormal cell growth disorder comprising same as an active ingredient.
摘要:
Disclosed is a method of fabricating a liquid crystal display (LCD) device in which a photosensitive film is selectively patterned using a half-tone mask, and then a portion of a passivation layer at a pixel area is selectively removed to secure an penetration path of a stripper. Additionally, a crack is generated on a conductive film formed on a photosensitive film pattern through a predetermined heat treatment to facilitate a lift-off process. Thus, the number of masks can be reduced to simplify the fabrication process of the LCD device and reduce fabrication costs.
摘要:
Disclosed is a method for processing messages in a mobile terminal having a communication service cutoff mode for disabling voice calls and message transmissions. The method includes the steps of storing one or more input messages when a user presses a key to send the messages during the communication service cutoff mode and automatically sending each stored message to a corresponding recipient upon cancellation of the communication service cutoff mode. The messages input during the communication service cutoff mode are automatically sent to corresponding recipients upon cancellation of that mode, thereby improving user convenience.