摘要:
The present invention is related to novel use of 2-oxo-heterocyclic compounds having anticancer activity and the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the cancer disease comprising lung cancer, bone cancer, pancreatic cancer, skin cancer, cancer of the head and neck, cutaneous or intraocular melanoma, uterine cancer, ovarian cancer, rectal cancer or cancer of the anal region, stomach cancer, colon cancer, breast cancer, gynecologic tumors, Hodgkin's disease, cancer of the esophagus, cancer of the small intestine, cancer of the endocrine system, sarcomas of soft tissues, cancer of the urethra, cancer of the penis, prostate cancer, chronic or acute leukemia, solid tumors of childhood, lymphocytic lymphonas, cancer of the bladder, cancer of the kidney or ureter, or neoplasms of the central nervous system, therefore, it can be used as the therapeutics for treating and preventing cancer diseases.
摘要:
A first method of manufacturing a printed circuit board includes steps of (a) preparing a board which has a chip mounting area and circuit patterns on an upper surface and metal pads to be electrically connected to the circuit patterns on a lower surface, (b) attaching a metal plate to the lower surface of the board, (c) forming metal patterns on the metal pads by etching the metal plate, and (d) forming metal bumps by plating the metal patterns. A second method of manufacturing a circuit board, in this case a flexible circuit board, includes the steps of (a) preparing a board having Cu patterns, plated with a Au layer, attached to a lower surface of a polyimide tape, (b) forming a plurality of via holes in the polyimide tape, which expose the Cu patterns to the upper surface of the polyimide tape, (c) coating the upper surface of the polyimide tape with a photoresist, and exposing and developing the photoresist to form openings therein which expose the via holes, (d) plating walls, defining the openings and the via holes, with Cu, (e) removing remaining portions of the photoresist to produce Cu bumps, and (f) plating the bumps to protect the Cu. The printed circuit boards of the present invention have advantages in that they are not subject to a misalignment of the metal bumps with their underlying conductive pattern, and eliminate the need to use flux, thereby being environmentally friendly.
摘要:
A first method of manufacturing a printed circuit board includes steps of (a) preparing a board which has a chip mounting area and circuit patterns on an upper surface and metal pads to be electrically connected to the circuit patterns on a lower surface, (b) attaching a metal plate to the lower surface of the board, (c) forming metal patterns on the metal pads by etching the metal plate, and (d) forming metal bumps by plating the metal patterns. A second method of manufacturing a circuit board, in this case a flexible circuit board, includes the steps of (a) preparing a board having Cu patterns, plated with a Au layer, attached to a lower surface of a polyimide tape, (b) forming a plurality of via holes in the polyimide tape, which expose the Cu patterns to the upper surface of the polyimide tape, (c) coating the upper surface of the polyimide tape with a photoresist, and exposing and developing the photoresist to form openings therein which expose the via holes, (d) plating walls, defining the openings and the via holes, with Cu, (e) removing remaining portions of the photoresist to produce Cu bumps, and (f) plating the bumps to protect the Cu. The printed circuit boards of the present invention have advantages in that they are not subject to a misalignment of the metal bumps with their underlying conductive pattern, and eliminate the need to use flux, thereby being environmentally friendly.
摘要:
Disclosed herein is an apparatus for jetting droplets using an electrostatic field, the apparatus includes a body, a chamber, an actuator, a nozzle, and a pillar-shaped member. The body is configured to contain and support a chamber, an actuator, a nozzle, and a pillar-shaped member and configured. The chamber is formed to have a predetermined volume in the body and accommodate a predetermined amount of fluid. The actuator is formed on the body, and configured to jet the fluid accommodated in the chamber using a controllable electrostatic field. The nozzle is configured to pass through the upper portion of the chamber and the central portion of the actuator, and to allow the fluid accommodated in the chamber to flow therethrough. The pillar-shaped member is located in a direction extending from the longitudinal central axis of the nozzle, and is configured to be electrically grounded and guide the fluid to smoothly flow to the inlet of the nozzle.
摘要:
Some embodiments of the present invention are related to devices and methods for sampling groundwater at multiple target depths, wherein each of the devices for sampling groundwater at multiple target depths comprises: a hammer part having a spring for generating inertia and a hammer connected to the spring; a sampling needle part having a needle integral with a impacting part impacted with the hammer; a guiding part for moving the sampling needle part in straight and downward direction; and a sampled water containing part having a sampled water container for collecting the sampled water through the needle.
摘要:
A hinge device for a storage container which includes a pair of hinge couplers combined in the form of a single unit, and enables a door of the storage container to be more smoothly closed without generating impact. A storage container, which includes the hinge device, is also disclosed. The hinge device includes a housing fixed to a container body of the storage container or the door, a first hinge shaft and a second hinge shaft rotatably coupled to the housing at opposite sides of the housing, respectively, each of the first and second hinge shafts having one end extending into the housing, and the other end extending outwardly beyond the housing and fixedly coupled to the other one of the container body and the door, a driver arranged in the housing at the side of the first hinge shaft to apply, to the first hinge shaft, a rotating force to cause the door to be maintained in an opened state or to be closed in accordance with an opening angle of the door, and a damper arranged in the housing at the side of the second hinge shaft to increase a resistance to rotation of the second hinge shaft, and thus, to cause the door to be smoothly closed.
摘要:
A method of obtaining a location of a user includes obtaining first location information of the user; searching a pre-stored first map for a plurality of candidate areas corresponding to the first location information; selecting at least one search area from the plurality of candidate areas corresponding to the first location information based on second location information of the user; and determining the location of the user using at least one search area.
摘要:
Provided are a method and apparatus for measuring a location of a terminal using a magnetic field. For example, the apparatus may measure a location of a terminal using a magnetic field obtained by a magnetic field sensor and one or more sensor values obtained by a plurality of other sensors.
摘要:
Provided are an apparatus and method for estimating a location of the terminal using multiple location estimating schemes. The apparatus and method may estimate the location of the terminal more accurately by controlling initial conditions for a plurality of location estimating units, for example, a start time for estimating locations, initial parameters for location estimating schemes, and the like.
摘要:
A method of calculating an accuracy of measuring a location, and a method and apparatus to measure a location of a terminal using the accuracy of measuring the location, are provided. The method of calculating the accuracy of measuring the location of the terminal includes providing a map corresponding to a location measurement type that is used in the terminal. The method further includes reading, from the map, map information of a predetermined area including the location of the terminal. The method further includes calculating the accuracy of measuring the location with the location measurement type based on the map information.