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公开(公告)号:US20220378410A1
公开(公告)日:2022-12-01
申请号:US17875589
申请日:2022-07-28
Applicant: CARDIOVALVE LTD
Inventor: Gil HACOHEN , Yossi GROSS , Tal REICH
Abstract: A transluminal sheath is advanced transseptally into a left atrium of the subject. A distal end of a surrounding-sheath, having an anchor disposed therein, is advanced via a distal end of the transluminal sheath, into a left ventricle of the subject via a commissure of the mitral valve. While the distal end of the surrounding-sheath is in the left ventricle, the surrounding-sheath is pulled proximally with respect to the anchor to expose the anchor. While the distal end of the surrounding-sheath is in the left ventricle, mitral valve tissue that is within the left ventricle is encircled by helically wrapping the anchor around the mitral valve tissue. Subsequently, the surrounding-sheath is extracted from the heart. Other embodiments are also described.
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公开(公告)号:US20200046496A1
公开(公告)日:2020-02-13
申请号:US16656790
申请日:2019-10-18
Applicant: CARDIOVALVE LTD.
Inventor: Tal HAMMER , Meni IAMBERGER , Yaron HERMAN , Yuval ZIPORY , Eran HOFFER , Michael ALBITOV , Natalia KRUGLOVA , Tal REICH , Ilia HARITON , Aviram BAUM
IPC: A61F2/24
Abstract: A prosthetic valve includes a tubular valve body, snares, and an upstream support. A native valve of a heart of a subject is disposed between an atrium and a ventricle of the heart, and has an annulus and leaflets. The prosthetic valve is advanced to the heart while in a compressed state. The prosthetic valve is positioned within the heart such that the snares are disposed upstream of the annulus and leaflets. The snares are expanded radially outwardly upstream of the leaflets. Subsequently, the prosthetic valve is moved in a downstream direction such that the snares become disposed downstream of the leaflets. While the snares remain downstream of the leaflets, the upstream support is expanded within the atrium, and the upstream support is placed against an upstream surface of the annulus. Other embodiments are also described.
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公开(公告)号:US20240216128A1
公开(公告)日:2024-07-04
申请号:US18601399
申请日:2024-03-11
Applicant: CARDIOVALVE LTD.
Inventor: Yossi GROSS , Gil HACOHEN , Eran MILLER , Yuval ZIPORY , Tal REICH , Meir KUTZIK , Rotem NEEMAN
IPC: A61F2/24 , A61B17/00 , A61B17/122 , A61F2/848
CPC classification number: A61F2/2418 , A61B17/122 , A61F2/2409 , A61F2/2436 , A61F2/2439 , A61F2/2454 , A61F2/246 , A61F2/2466 , A61B2017/00243 , A61F2/2427 , A61F2/2433 , A61F2/2442 , A61F2/2445 , A61F2/2463 , A61F2/848 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/0091 , A61F2230/0006 , A61F2230/0013 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0015 , A61F2250/006 , A61F2250/0069 , A61F2250/0071
Abstract: For some applications, apparatus is provided for facilitating implantation of a prosthetic valve (150) at a native heart valve (120) of a subject, the apparatus comprising a prosthetic valve support (22), the prosthetic valve support (a) being configured to be transluminally-deliverable to the native valve and to be deployable at the native valve, and (b) comprising one or more tissue-engaging elements (24), configured to couple the prosthetic valve support to leaflets (128) of the native valve without eliminating check valve functionality of the native valve. Other embodiments are also described.
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公开(公告)号:US20230248352A1
公开(公告)日:2023-08-10
申请号:US18136504
申请日:2023-04-19
Applicant: CARDIOVALVE LTD.
Inventor: Yossi GROSS , Gil HACOHEN , Eran MILLER , Yuval ZIPORY , Tal REICH
CPC classification number: A61B17/0401 , A61F2/2409 , A61F2/2418 , A61F2/2436 , A61F2/2457 , A61F2/2466 , A61F2/2427 , A61F2/243 , A61F2/2412 , A61F2220/0016 , A61F2230/0041 , A61F2230/005 , A61B2017/00243
Abstract: Apparatus and methods are described including a prosthetic valve support (40) configured to be placed at a patient's native atrioventricular valve annulus. The valve support defines an annular element (44) that defines an inner cross-sectional area thereof. An expandable prosthetic valve (80) is placed into the patient's ventricle, the prosthetic valve including an expandable frame (79) and prosthetic valve leaflets (82) coupled to the frame. When the frame is in a non-constrained state thereof, a cross-sectional area of the frame, along at least a given portion L of the frame's length, is greater than the cross-sectional area defined by the annular element. The prosthetic valve is couplable to the prosthetic valve support at any location along the portion, by the frame being expanded when the location along the portion is aligned with the annular element. Other applications are also described.
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公开(公告)号:US20200315789A1
公开(公告)日:2020-10-08
申请号:US16738516
申请日:2020-01-09
Applicant: CARDIOVALVE LTD.
Inventor: Ilia HARITON , Tal REICH , Paul KAYE
Abstract: A method is provided, including (1) identifying the subject as having mitral valve regurgitation; (2) during a medical procedure, in response to identifying the subject as having mitral valve regurgitation, implanting a prosthetic valve at a mitral valve site of the heart; and (3) during the same medical procedure, implanting a therapeutic septal device at a septum of the heart. Other embodiments are also described.
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公开(公告)号:US20190321172A1
公开(公告)日:2019-10-24
申请号:US16460313
申请日:2019-07-02
Applicant: CARDIOVALVE LTD.
Inventor: Yossi GROSS , Gil HACOHEN , Eran MILLER , Tal REICH
IPC: A61F2/24
Abstract: An apparatus for use with a prosthetic heart valve at a native heart valve comprises an adjustable-lumen prosthetic valve support. In a delivery state, the prosthetic valve support is transluminally deliverable to the heart. The prosthetic valve support is transitionable, within the heart, into an implantation state for implantation at the native valve. In the implantation state, the prosthetic valve support has an inner edge that defines a lumen through the prosthetic valve support, the lumen having a first diameter. After the prosthetic valve support is implanted at the native valve, the prosthetic valve support is transitionable into an enlarged state in which the lumen has a second diameter that is greater than the first diameter. In the enlarged state, the prosthetic valve support is configured to support, at the native valve, the prosthetic heart valve within the lumen.
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公开(公告)号:US20200146671A1
公开(公告)日:2020-05-14
申请号:US16740659
申请日:2020-01-13
Applicant: CARDIOVALVE LTD.
Inventor: Gil HACOHEN , Yossi GROSS , Tal REICH
Abstract: Prosthetic heart valves and methods of use of prosthetic heart valves may be provided. In one implementation, a prosthetic heart valve may include an annular spacer configured for implantation with a native heart valve opening and a central valve section configured for disposal within the annular spacer. The central valve section may include at least one anchoring protrusion configured to anchor the central valve section against axial movement relative to the annular spacer. During deployment, the central valve section may be advanced downstream beyond the implanted annular spacer, and moved upstream until the anchoring protrusion engages the annular spacer.
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公开(公告)号:US20230049163A1
公开(公告)日:2023-02-16
申请号:US17683875
申请日:2022-03-01
Applicant: CARDIOVALVE LTD.
Inventor: Ilia HARITON , Tal REICH , Paul KAYE
Abstract: During a medical procedure, a transseptal fenestration is made at a septum of the heart and a shunt is implanted into the transseptal fenestration. During the same medical procedure, a transapical puncture is made into a left ventricle of the heart. A prosthetic valve is delivered via the transapical puncture and implanted at a mitral valve of the heart. Subsequently to delivering the prosthetic valve and making the transseptal fenestration, the transapical puncture is closed. Other embodiments are also described.
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公开(公告)号:US20240058123A1
公开(公告)日:2024-02-22
申请号:US18385643
申请日:2023-10-31
Applicant: CARDIOVALVE LTD.
Inventor: Tal HAMMER , Yuval ZIPORY , Tal REICH , Yaron HERMAN , Gil HACOHEN , Eran MILLER , Rotem NEEMAN , Natalia KRUGLOVA
IPC: A61F2/24
CPC classification number: A61F2/2427 , A61F2/2436 , A61F2/2418 , A61F2/2409 , A61F2220/0075 , A61F2250/0098 , A61F2220/0025 , A61F2220/0016 , A61F2210/0076
Abstract: Apparatus is provided, including: (A) a valve body (204) including a first frame (206) shaped to define a lumen therethrough, and a valve member (205) disposed within the lumen, (B) an upstream support (210), configured to be placed against an upstream surface of a native heart valve, and (C) a flexible sheet (214) that couples the upstream support to the valve body. The valve body has a compressed state in which the first frame has a first diameter, and an expanded state in which the first frame has a second diameter that is greater than the first diameter. The support includes a second frame (212) that has a compressed state, and an expanded state in which the second frame is annular, has an inner perimeter that defines an opening through the second frame, and has an outer perimeter. Other embodiments are also described.
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公开(公告)号:US20210169467A1
公开(公告)日:2021-06-10
申请号:US17181961
申请日:2021-02-22
Applicant: CARDIOVALVE LTD.
Inventor: Gil HACOHEN , Yossi GROSS , Tal REICH
Abstract: Prosthetic heart valves and methods of use of prosthetic heart valves may be provided. In one implementation, a prosthetic heart valve may include an annular spacer configured for implantation with a native heart valve opening and a central valve section configured for disposal within the annular spacer. The central valve section may include at least one anchoring protrusion configured to anchor the central valve section against axial movement relative to the annular spacer. During deployment, the central valve section may be expanded radially within the heart into an at least partially-expanded configuration while at least a portion of the central valve section is situated outside of a space opening of the annular spacer, and moved upstream while remaining in the at least partially-expanded configuration until the anchoring protrusion engages the annular spacer.
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