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公开(公告)号：US20170226476A1
公开(公告)日：2017-08-10
申请号：US15502699
申请日：2015-08-06
Applicant: CEFO CO., LTD
Inventor： Hyun Sook PARK , Sun Ray LEE , Jin Yup LEE , Hyun Jung MO
IPC: C12N5/0735 , C12N5/071 , C12N5/0797 , C12N5/074 , C12N5/0775
CPC classification number: C12N5/0606 , A01N1/021 , C12N5/0611 , C12N5/0623 , C12N5/0663 , C12N5/0665 , C12N5/0667 , C12N5/067 , C12N5/0696
Abstract: The present invention relates to a composition for preserving cells and a method for preserving cells and, more specifically, to: a composition for preserving cells, containing, as active ingredients, plant-derived recombinant human serum albumin and plant peptides, wherein the composition maintains a high cellular survival rate while maintaining animal-free and xeno-free properties and is stable without changes in cellular morphology or surface expression factors in the short-term preservation of cells such as stem cells or primary cultured cells; and a method for preserving cells by using the same.
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公开(公告)号：US20170283767A1
公开(公告)日：2017-10-05
申请号：US15512466
申请日：2015-09-15
Applicant: CEFO CO., LTD
Inventor： Hyun Sook PARK , Sun Ray LEE , Ji Won YANG , Seol CHU , Jang Mi PARK , Hyun Jung MO
CPC classification number: C12N5/0062 , A01N1/02 , A61K35/12 , A61L27/38 , A61L27/60 , C12M3/00 , C12M25/14 , C12N5/00
Abstract: The present invention relates to a composition for preserving cells and a cell preservation method and, more specifically: to a composition for preserving cells, containing, as active ingredients, a plant-derived recombinant human serum albumin and a plant peptide, which maintain a high cell survival rate while maintaining animal-free and xeno-free properties and are stable without changes in cell morphology or a surface expression factor during the short term preservation of cells such as stem cells or primary cultured cells; and a cell preservation method using the same.
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3.发明公开公开(公告)号：US20230248776A1
公开(公告)日：2023-08-10
申请号：US17918093
申请日：2021-10-08
Applicant: CEFO Co., Ltd.
Inventor： Hyun Sook PARK , Yeon Kyung LEE , Eun Jin GO , Ha Jin KIM , Sun Ray LEE , Ah Reum KWON
Abstract: The present invention relates to a method for differentiating mesenchymal stem cells into osteoblasts, a cell therapeutic agent for treating bone disease including osteoblasts differentiated by the method and a method for producing the same. In addition, the present invention relates to a method for treating bone disease, including the step of administering the osteoblasts obtained by the method to a patient with bone disease.
The differentiation method according to the present invention can stably and rapidly differentiate mesenchymal stem cells into osteoblasts. The differentiated osteoblasts have excellent blood vessel-forming ability and excellent bone-forming ability. Accordingly, the method for differentiating stem cells into osteoblasts and the osteoblasts obtained by the method, according to the present invention, can be effectively used as a cell therapeutic agent or treatment method related to bone disease.-
4.发明申请公开(公告)号：US20170283768A1
公开(公告)日：2017-10-05
申请号：US15512455
申请日：2015-09-15
Applicant: CEFO CO., LTD
Inventor： Hyun Sook PARK , Sun Ray LEE , Ji Won YANG , Seol CHU , Hyun Jung MO
IPC: C12N5/00 , C12N5/0775 , C12N5/073
CPC classification number: C12N5/0068 , C12M3/00 , C12M25/14 , C12N5/00 , C12N5/0603 , C12N5/0663 , C12N5/0667 , C12N5/0668 , C12N2513/00 , C12N2533/30 , C12N2537/10
Abstract: The present invention relates to a method for inducing osteogenic differentiation of mesenchymal stem cells and, more particularly, to a short-time osteogenic differentiation method of culturing cells using a porous membrane and a biodegradable synthetic biogel, whereby the cells do not contact a cell culture container. The present invention can significantly shorten the induction period of osteogenic differentiation, compared to the conventional osteogenic differentiation method, and has an effect of the cells being easily separable after differentiation as well.
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