公开(公告)号：US20060134792A1

公开(公告)日：2006-06-22

申请号：US10567072

申请日：2004-08-02

申请人： Cheol-Min Kim ,  Hee-Kyung Park ,  Mong Cho ,  Hyun-Jung Jang ,  Jeong Heo

发明人： Cheol-Min Kim ,  Hee-Kyung Park ,  Mong Cho ,  Hyun-Jung Jang ,  Jeong Heo

IPC分类号： C12Q1/00

CPC分类号： C12Q1/706 ,  C12Q1/6837 ,  C12Q2545/113

摘要： Provided are a microarray manufactured using a mixture of target probes for drug-resistant HBV detection, quality control probes for controlling quality in probe hybridization and fabrication of microarrays, and negative control probes for determining the presence and ratio of more than one type, i.e., a wild type and a mutant in a codon, measuring a background of non-specific cross-hybridization, and discriminating homozygotes and heterozygotes, and a method of detecting a drug-resistant HBV, controlling the quality of a microarray, determining the presence and ratio of more than one type, and determining positive and false positive probes at the same time using the microarray. The microarray, which includes the target probes for drug-resistant HBV detection, the QC probes, and the negative control probes, can detect a drug-resistant HBV, control quality in fabrication of microarrays and hybridization, determine the presence and ratio of more than one type, i.e., a wild type and a mutant, determine positive and false positive probes by measuring a background of non-specific cross-hybridization, and discriminate homozygotes and heterozygotes. When a plurality of sets of probes, each set containing target probes, QC probes, and negative control probes, are immobilized on a support of the microarray, detection of resistance in HBV to multiple drugs, quality control, and determination as to the presence and ratio of a wild type and a mutant and whether each probe is positive or false positive can be rapidly and accurately performed.

摘要翻译： 提供了使用用于耐药HBV检测的靶探针混合物制造的微阵列，用于控制探针杂交质量的控制探针和微阵列的制造以及用于确定多于一种类型的存在和比例的阴性对照探针， 密码子中的野生型和突变体，测量非特异性交叉杂交的背景，以及鉴别纯合子和杂合子，以及检测耐药性HBV的方法，控制微阵列的质量，确定存在和比例 的多种类型，并使用微阵列同时确定阳性和假阳性探针。 包括用于耐药HBV检测的目标探针，QC探针和阴性对照探针的微阵列可以检测耐药性HBV，控制微阵列和杂交的制备质量，确定多于一个的存在和比例 一种类型，即野生型和突变体，通过测量非特异性交叉杂交的背景，并鉴别纯合子和杂合子来确定阳性和假阳性探针。 当将包含目标探针，QC探针和阴性对照探针的多组探针固定在微阵列的载体上时，检测HBV对多种药物的耐药性，质量控制和确定存在和 野生型和突变体的比例以及每种探针是阳性还是假阳性可以快速和准确地进行。

公开(公告)号：US20080261206A1

公开(公告)日：2008-10-23

申请号：US11574405

申请日：2005-08-28

申请人： Cheol-Min Kim ,  Hee-Kyung Park ,  Eun-Sil Song ,  Jun-Hyung Park ,  Hyun-Jung Jang ,  Byeong-Chul Kang

发明人： Cheol-Min Kim ,  Hee-Kyung Park ,  Eun-Sil Song ,  Jun-Hyung Park ,  Hyun-Jung Jang ,  Byeong-Chul Kang

IPC分类号： C12Q1/68 ,  C40B40/06 ,  C07H21/00

CPC分类号： C12Q1/689 ,  C12Q1/6837

摘要： The present invention relates to a method so called Bacterial Digitalcode System (BaDis) that identifies microorganism by using bacterial-specific, genus-specific and species-specific oligonucleotides from a variety of samples or specimens for detection and differential diagnosis of microorganism. Particularly, the present invention relates to bacterial-specific, genus-specific and species-specific oligonucleotides designed by the target nucleotide sequences of 23S rDNA or ITS gene, polymerase chain reaction (hereinafter, referred to as “PCR”) kits using the oligonucleotides as a primer, the microarray containing the oligonucleotides as a probe, and methods for detecting microorganism by using the oligonucleotides. Therefore, the present invention can be applied to detect the presence of microorganism and diagnose differentially all microorganism such as pathogenic bacteria of infectious diseases, bacteria inducing food poisoning, bacteria contaminating biomedical products and environmental pollutants.

摘要翻译： 本发明涉及一种所谓的细菌数字代码系统（BaDis）的方法，其通过使用来自各种样品或样品的细菌特异性，属特异性和物种特异性寡核苷酸来鉴定微生物，用于微生物的鉴定和鉴别诊断。 特别地，本发明涉及由23S rDNA或ITS基因的靶核苷酸序列设计的细菌特异性，属特异性和物种特异性寡核苷酸，使用寡核苷酸作为聚合酶链反应（以下称为“PCR”）试剂盒 引物，含有寡核苷酸作为探针的微阵列，以及通过使用寡核苷酸检测微生物的方法。 因此，本发明可以应用于检测微生物的存在并差异地诊断所有微生物，如感染性疾病的病原菌，诱导食物中毒的细菌，细菌污染的生物医学产品和环境污染物。

公开(公告)号：US20090286691A1

公开(公告)日：2009-11-19

申请号：US12161691

申请日：2006-01-20

申请人： Cheol-Min Kim ,  Hee-Kyung Park ,  Hyun-Jung Jang ,  Eun-Sil Song

发明人： Cheol-Min Kim ,  Hee-Kyung Park ,  Hyun-Jung Jang ,  Eun-Sil Song

IPC分类号： C40B30/04 ,  C07H21/04 ,  C12Q1/68 ,  C40B40/06 ,  C40B40/08

CPC分类号： C12Q1/689

摘要： The present invention relates to oligonucleotides for detection of sepsis-causing bacteria and a detection method using the oligonucleotides, more particularly to a microarry comprising at least one of gram positive bacteria-specific and gram negative bacteria-specific oligonucleotides, sepsis-causing bacteria's genus-specific and species-specific oligonucleotides designed from the ITS target region which is hypervariable base sequence of sepsis-causing bacteria as probes, and a detection method and a diagnosis kit by using the same.According to the present invention, the present invention can provide an antibiotics therapy for accurately removing infectious agent related to sepsis by detecting existence of sepsis-causing bacteria and identifying gram positive- and gram negative-bacteria and genus and species of the bacteria, at once. And, the present invention can prevent a patient from abuse and misuse of antibiotics and decrease time of hospital treatment and medical cost of the patient. Further, the present invention has advantage of preventing complications and reducing mortality rate.

摘要翻译： 本发明涉及用于检测败血症细菌的寡核苷酸和使用寡核苷酸的检测方法，更具体地涉及包含革兰氏阳性细菌特异性和革兰氏阴性细菌特异性寡核苷酸中的至少一种的微阵列，败血症细菌的属 - 由作为败血症的细菌作为探针的高变碱基序列的ITS靶区设计的特异性和物种特异性寡核苷酸，以及使用该检测方法和诊断试剂盒。 根据本发明，本发明可以提供一种用于通过检测脓毒症引起的细菌的存在并一次鉴定革兰氏阳性和革兰氏阴性细菌以及细菌的种类和物种来精确地去除与败血症相关的传染原的抗生素治疗 。 并且，本发明可以防止患者滥用和滥用抗生素，并减少患者的医院治疗时间和医疗费用。 此外，本发明具有防止并发症和降低死亡率的优点。

公开(公告)号：US20070065828A1

公开(公告)日：2007-03-22

申请号：US10597173

申请日：2005-01-14

申请人： Cheol-Min Kim ,  Hee-Kyung Park ,  Hyun-Jung Jang ,  Hyo-Myoung Kim

发明人： Cheol-Min Kim ,  Hee-Kyung Park ,  Hyun-Jung Jang ,  Hyo-Myoung Kim

IPC分类号： C12Q1/68 ,  C12M3/00

CPC分类号： C12Q1/689

摘要： The present invention relates to a method for detecting Mycoplasma and its related strains which are source of contamination of cell lines and biological products and human pathogenic. More particularly, the present invention relates to genus-specific and species-specific oligonucleotides for genotyping of Mycoplasma, Acholeplasm and Ureaplasma strains, microarray comprising the oligonucleotides, and method for detection of species using the microarray. As described above, the present invention provides a rapid and accurate assay method capable of simultaneously detecting many Mycoplasma and its related strains from a single sample using a microarray comprising novel oligonucleotides for detecting Mycoplasma and its related strains which are known as a source of contamination of cell lines and biological products and human pathogenic. Further, the present invention provides an objective and credible assay method capable of tracing a contamination source for preventing expansion of infective Mycoplasma and its related strains and controlling a contamination of Mycoplasma against biological products and stem cells or cord blood cells which are useful for gene therapy and cell therapy.

摘要翻译： 本发明涉及一种检测支原体及其相关菌株的方法，这些菌株是细胞系和生物制品的污染源和人类致病菌。 更具体地说，本发明涉及用于基因分型支原体，痘苗和解脲支原体菌株的特异性和物种特异性寡核苷酸，包含寡核苷酸的微阵列，以及使用微阵列检测物种的方法。 如上所述，本发明提供了一种快速且准确的测定方法，其能够使用包含用于检测支原体及其相关菌株的微阵列的微阵列同时检测许多支原体及其相关菌株，所述新型寡核苷酸及其相关菌株被称为污染源 细胞系和生物制品和人类致病性。 此外，本发明提供了一种客观且可靠的测定方法，其能够追踪污染源以防止感染性支原体及其相关菌株的扩增，并控制支原体对生物制品和干细胞或脐带血细胞的污染，这些基因治疗可用于基因治疗 和细胞治疗。

公开(公告)号：US07688292B2

公开(公告)日：2010-03-30

申请号：US11373671

申请日：2006-03-09

申请人： Kee-Chan Park ,  Ho-Suk Maeng ,  Seong-Il Park ,  Cheol-Min Kim ,  Chi-Woo Kim ,  Soong-Yong Joo ,  Il-Gon Kim

发明人： Kee-Chan Park ,  Ho-Suk Maeng ,  Seong-Il Park ,  Cheol-Min Kim ,  Chi-Woo Kim ,  Soong-Yong Joo ,  Il-Gon Kim

IPC分类号： G09G3/32

CPC分类号： G09G3/3233 ,  G09G2300/0819 ,  G09G2300/0852 ,  G09G2300/0861 ,  G09G2320/043

摘要： A display device includes a plurality of pixels, wherein each pixel includes: a light emitting element; a first capacitor connected between a first node and a second node; a driving transistor having an input terminal, an output terminal, and a control terminal connected to the second node where the driving transistor supplies a driving current to the light emitting element to emit light; a first switching unit supplying a first reference voltage to the driving transistor according to a first scanning signal and connecting the first node to a data voltage or the driving transistor; and a second switching unit supplying a driving voltage to the driving transistor according to a second scanning signal and connecting the first node to the data voltage. Accordingly, variations in threshold voltage of the driving transistor can be compensated for so that it is possible to display a uniform image.

摘要翻译： 显示装置包括多个像素，其中每个像素包括：发光元件; 连接在第一节点和第二节点之间的第一电容器; 驱动晶体管，其具有输入端子，输出端子和连接到所述第二节点的控制端子，其中所述驱动晶体管向所述发光元件提供驱动电流以发光; 第一开关单元，根据第一扫描信号向驱动晶体管提供第一参考电压，并将第一节点连接到数据电压或驱动晶体管; 以及第二开关单元，其根据第二扫描信号向驱动晶体管提供驱动电压，并将第一节点连接到数据电压。 因此，可以补偿驱动晶体管的阈值电压的变化，使得可以显示均匀的图像。

公开(公告)号：US20080191989A1

公开(公告)日：2008-08-14

申请号：US11856424

申请日：2007-09-17

申请人： Jae-Sic Lee ,  Il-Gon Kim ,  Cheol-Min Kim

发明人： Jae-Sic Lee ,  Il-Gon Kim ,  Cheol-Min Kim

IPC分类号： G09G3/36

CPC分类号： G09G3/3688 ,  G09G3/3614 ,  G09G3/3659 ,  G09G2310/0281 ,  G09G2330/021

摘要： A liquid crystal display (LCD) panel includes a plurality of data and gate lines, a plurality of main switching elements, and a plurality of liquid crystal capacitors. Each main switching element is electrically connected to a main data and gate line. Each liquid crystal capacitor is electrically connected to a main switching element. The LCD panel further includes a plurality of partial gate lines to transmit a plurality of partial driving signals, a plurality of partial data lines to transmit a plurality of data signals, and a plurality of partial switching elements. Each partial switching element is turned on based on a partial driving signal to provide a memory with a data signal via a partial data line when a main switching element is enabled, and to provide a liquid crystal capacitor with a data signal stored in the memory when the main switching element is turned off.

摘要翻译： 液晶显示器（LCD）面板包括多个数据和栅极线，多个主开关元件和多个液晶电容器。 每个主开关元件电连接到主数据和门线。 每个液晶电容器电连接到主开关元件。 LCD面板还包括多个部分栅极线，用于传输多个部分驱动信号，多个部分数据线以发送多个数据信号，以及多个部分开关元件。 每个部分开关元件基于部分驱动信号导通，以在主开关元件使能时通过部分数据线提供具有数据信号的存储器，并且为液晶电容器提供存储在存储器中的数据信号，当 主开关元件关闭。

公开(公告)号：US20070171177A1

公开(公告)日：2007-07-26

申请号：US11623398

申请日：2007-01-16

申请人： Cheol-Min Kim ,  Il-Gon Kim ,  Tae-Hyeong Park ,  Gi-Chang Lee ,  Oh-Kyong Kwon

发明人： Cheol-Min Kim ,  Il-Gon Kim ,  Tae-Hyeong Park ,  Gi-Chang Lee ,  Oh-Kyong Kwon

IPC分类号： G09G3/36

CPC分类号： G09G3/20 ,  G09G3/2011 ,  G09G3/3688 ,  G09G2310/027 ,  G09G2310/08 ,  G09G2330/021

摘要： A driving device for a display device includes a gray voltage generator generating a plurality of gray voltages, a voltage selector selecting an output voltage from the plurality of gray voltages, a voltage level converter converting a level of the output voltage selected by the voltage selector and applying the output voltage with a converted level to data lines, a first switching unit connecting the voltage level converter to the voltage selector and the data lines, and a second switching unit directly connecting the voltage selector and the data lines. Operating times of the first and second switching units are different. Accordingly, when a data voltage is charged in or discharged from a data line, since a separate discharging transistor or a separate discharging amplifier is not used, power consumption and an area of a data driver are reduced.

摘要翻译： 一种用于显示装置的驱动装置包括产生多个灰度电压的灰度电压发生器，选择多个灰度电压的输出电压的电压选择器，转换由电压选择器选择的输出电压电平的电压电平转换器和 将转换电平的输出电压施加到数据线，将电压电平转换器连接到电压选择器和数据线的第一开关单元，以及直接连接电压选择器和数据线的第二开关单元。 第一和第二开关单元的工作时间不同。 因此，当数据电压被充电到数据线或从数据线放电时，由于不使用单独的放电晶体管或单独的放电放大器，所以功耗和数据驱动器的面积减小。

公开(公告)号：US07240502B2

公开(公告)日：2007-07-10

申请号：US10917287

申请日：2004-08-13

申请人： Eun-Jun Cho ,  Yoon-Jei Hwang ,  Yun-Ho Ryu ,  Cheol-Min Kim ,  Chan-Ho Song ,  Chang-Min Choi ,  Ji-Young Jang ,  Young-Seob Choi ,  Woo-Ho Cha ,  Seung-Youp Hyun ,  Won-Hee Lee

发明人： Eun-Jun Cho ,  Yoon-Jei Hwang ,  Yun-Ho Ryu ,  Cheol-Min Kim ,  Chan-Ho Song ,  Chang-Min Choi ,  Ji-Young Jang ,  Young-Seob Choi ,  Woo-Ho Cha ,  Seung-Youp Hyun ,  Won-Hee Lee

IPC分类号： F25B7/00 ,  F25B41/00 ,  F25B49/00

CPC分类号： F25B49/022 ,  F25B2400/0751 ,  F25B2600/021 ,  F25B2600/0251 ,  Y02B30/741

摘要： A method for controlling operations of an air-conditioner includes: a step in which when an operation load of an air-conditioner increases, if an outputted compressing capacity of the air-conditioner is smaller than a compressing capacity corresponding to the operation load and an operation frequency of the first compressor is a maximum frequency of the first compressor, a second compressor is operated; and a step in which when the operation load is reduced, if the outputted compressing capacity of the air-conditioner is greater than the compressing capacity corresponding to the operation load and the operation frequency of the first compressor is a minimum frequency of the first compressor, the second compressor is stopped.

摘要翻译： 一种用于控制空调的操作的方法包括：当空调的操作负载增加时，如果空调的输出压缩容量小于与操作负载相对应的压缩容量，则 第一压缩机的运转频率是第一压缩机的最大频率，第二压缩机运转; 以及当操作负载减小时，如果空调的输出压缩容量大于对应于操作负载的压缩容量，并且第一压缩机的操作频率是第一压缩机的最小频率， 第二压缩机停止。

公开(公告)号：US20060267915A1

公开(公告)日：2006-11-30

申请号：US11497996

申请日：2006-08-02

申请人： Kook-Chul Moon ,  Il-Gon Kim ,  Tae-Hyeong Park ,  Chul-Ho Kim ,  Cheol-Min Kim ,  Kee-Chan Park

发明人： Kook-Chul Moon ,  Il-Gon Kim ,  Tae-Hyeong Park ,  Chul-Ho Kim ,  Cheol-Min Kim ,  Kee-Chan Park

IPC分类号： G09G3/36

CPC分类号： G09G3/3688 ,  G09G2320/0233 ,  H03F3/3022 ,  H03F3/45179 ,  H03F2200/516

摘要： An amplifier includes a biasing section, first and second differential amplifying sections and an output section. The biasing section outputs first and second bias currents based on first and second power source voltages. The first differential amplifying section outputs a first amplified voltage based on the first bias current. The second differential amplifying section outputs a second amplified voltage based on the second bias current. The output section outputs the second power source voltage based on the first amplified voltage and the first power source voltage, and outputs the first power source voltage based on the second amplified voltage and the second power source voltage. Therefore, a variation of the threshold voltage is compensated to enhance display quality.

摘要翻译： 放大器包括偏置部分，第一和第二差分放大部分和输出部分。 偏置部分基于第一和第二电源电压输出第一和第二偏置电流。 第一差分放大部分基于第一偏置电流输出第一放大电压。 第二差分放大部分基于第二偏置电流输出第二放大电压。 输出部分基于第一放大电压和第一电源电压输出第二电源电压，并且基于第二放大电压和第二电源电压输出第一电源电压。 因此，补偿阈值电压的变化以增强显示质量。

公开(公告)号：US20060125811A1

公开(公告)日：2006-06-15

申请号：US11298338

申请日：2005-12-08

申请人： Kook Moon ,  Soong-Yong Joo ,  Ho-Suk Maeng ,  Seong-Il Park ,  Cheol-Min Kim ,  Tae-Hyeong Park ,  Il-Gon Kim ,  Chul-Ho Kim ,  Kee-Chan Park

发明人： Kook Moon ,  Soong-Yong Joo ,  Ho-Suk Maeng ,  Seong-Il Park ,  Cheol-Min Kim ,  Tae-Hyeong Park ,  Il-Gon Kim ,  Chul-Ho Kim ,  Kee-Chan Park

IPC分类号： G09G5/00

CPC分类号： G09G3/3677 ,  G09G2310/0289 ,  H03K19/018571

摘要： A level shifter includes: a voltage dividing unit receiving a first voltage and an input voltage, and generating a middle voltage between the first voltage and the input voltage; first and second voltage compensating units connected to the voltage dividing unit and connected between the first voltage and a second voltage, for compensating a voltage variation of the voltage dividing unit; and an output unit receiving an output from the voltage dividing unit and generating an output voltage.