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    High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds
    2.
    发明授权
    High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds 有权

    公开(公告)号：US09969751B2

    公开(公告)日：2018-05-15

    申请号：US13323556

    申请日：2011-12-12

    申请人： Chongxi Yu ,  Lina Xu ,  Yuhua Chen ,  Binbing Yan ,  Shiqian Tu

    发明人： Chongxi Yu ,  Lina Xu ,  Yuhua Chen ,  Binbing Yan ,  Shiqian Tu

    IPC分类号： C07D499/21

    CPC分类号： C07D499/21

    摘要： The invention provides compositions of novel high penetration compositions (HPC) or high penetration prodrugs (HPP) of antimicrobials and antimicrobial-related compounds, which are capable of crossing biological barriers with high penetration efficiency. The HPCs/HPPs are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, the HPPs are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPCs/HPPs can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.

    HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE-RELATED COMPOUNDS
    4.
    发明申请
    HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE-RELATED COMPOUNDS 有权
    肽和肽相关化合物的高渗透性原料组合物

    公开(公告)号：US20120156279A1

    公开(公告)日：2012-06-21

    申请号：US13291904

    申请日：2011-11-08

    申请人： Chongxi Yu ,  Lina Xu ,  Yuhua Chen ,  Binbing Yan ,  Shiqian Tu

    发明人： Chongxi Yu ,  Lina Xu ,  Yuhua Chen ,  Binbing Yan ,  Shiqian Tu

    IPC分类号： A61K9/70

    CPC分类号： A61K31/145 ,  A61K9/0014 ,  A61K31/222 ,  A61K31/40 ,  A61K31/4184 ,  A61K38/00 ,  A61K47/42 ,  A61K47/54 ,  A61K47/64 ,  A61K47/645 ,  C07D403/12 ,  C07D403/14 ,  C07K1/04 ,  C07K5/06026 ,  C07K5/06078 ,  C07K5/1013 ,  C07K5/1016 ,  C07K5/1019 ,  C07K7/06 ,  C07K7/56

    摘要： The invention provides compositions of novel high penetration compositions (HPC) or high penetration prodrugs (HPP) of peptides and peptide-related compounds, which are capable of crossing biological barriers with higher penetration efficiency comparing to their parent drugs. The HPPs are capable of being converted to parent drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, the HPPs/HPCs are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPPs/HPCs can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.

    摘要翻译： 本发明提供了肽和肽相关化合物的新型高渗透组合物（HPC）或高渗透前药（HPP）的组合物，其能够与其母体药物相比具有更高穿透效率的生物屏障。 HPP在穿过生物屏障后能够转化为母体药物或药物代谢物，因此可以对母体药物或代谢物可以进行的处理。 此外，HPP / HPC能够达到母体药物可能无法进入或在目标区域提供足够浓度的区域，从而进行新的治疗。 HPP / HPC可以通过各种施用途径施用于受试者，例如局部递送至具有高浓度或系统地施用于生物学受试者的病症的作用部位并以更快的速率进入总体循环。

    METHODS AND APPARATUSES FOR AUTHENTICATION IN QUANTUM KEY DISTRIBUTION AND/OR QUANTUM DATA COMMUNICATION
    5.
    发明申请
    METHODS AND APPARATUSES FOR AUTHENTICATION IN QUANTUM KEY DISTRIBUTION AND/OR QUANTUM DATA COMMUNICATION 审中-公开

    公开(公告)号：US20180048466A1

    公开(公告)日：2018-02-15

    申请号：US15556152

    申请日：2016-03-09

    申请人： Yuhua Chen

    发明人： Yuhua Chen

    IPC分类号： H04L9/08 ,  H04B10/70 ,  H04L9/32

    CPC分类号： H04L9/0852 ,  H04B10/70 ,  H04L9/32

    摘要： Systems and methods of authenticating and/or communicating key and/or data between communication parties using quantum channels are provided. In some embodiments, authentication may be provided during transmission (including at various stages), without transmission, before transmission, and/or without keys. Such systems and methods allow authentication to be performed on a bit-by-bit basis using the same quantum communication channel. Further, these systems and methods prevent an eaves-dropper from gaining useful information, and/or allow man-in-the-middle attacks to be detected.

    Method, user equipment, base station, and system for detecting sharing of timing advance value
    6.
    发明授权
    Method, user equipment, base station, and system for detecting sharing of timing advance value 有权
    方法，用户设备，基站和系统，用于检测定时提前价值的共享

    公开(公告)号：US08953541B2

    公开(公告)日：2015-02-10

    申请号：US13609045

    申请日：2012-09-10

    申请人： Yi Jang ,  Meylan Arnuad ,  Yuhua Chen ,  Wei Quan ,  Zhongbin Qin ,  Jian Zhang

    发明人： Yi Jang ,  Meylan Arnuad ,  Yuhua Chen ,  Wei Quan ,  Zhongbin Qin ,  Jian Zhang

    IPC分类号： H04W4/00 ,  H04W56/00

    CPC分类号： H04W56/0045

    摘要： Embodiments of the present invention disclose a method, user equipment, base station, and system for detecting sharing of a timing advance value, relate to the field of communications technologies, and solve a problem in the prior art that a normal service cannot be provided because a TA value cannot be shared between different uplink CCs. According to the embodiments of the present invention, the user equipment may determine, through a time offset between synchronization of downlink component carriers corresponding to uplink component carriers, that a too large time offset indicates that a same TA value cannot be shared; the base station may calculate a TA value directly through a dedicated preamble sequence, and then compares the TA value with a TA value of one of the component carriers, where a too large difference between the TA values indicates that a same TA value cannot be shared.

    摘要翻译： 本发明的实施例公开了一种用于检测定时提前价值的共享的方法，用户设备，基站和系统，涉及通信技术领域，并且解决了现有技术中由于不能提供正常服务的问题，因为 TA不能在不同的上行链路CC之间共享。 根据本发明的实施例，用户设备可以通过在与上行链路分量载波对应的下行链路分量载波的同步之间的时间偏移来确定太大的时间偏移指示不能共享相同的TA值; 基站可以通过专用前置码序列直接计算TA值，然后将TA值与分量载波之一的TA值进行比较，其中TA值之间的太大值表示不能共享相同的TA值 。

    METHODS AND APPARATUS FOR TRAFFIC MANAGEMENT IN MULTI-MODE SWITCHING DWDM NETWORKS
    7.
    发明申请
    METHODS AND APPARATUS FOR TRAFFIC MANAGEMENT IN MULTI-MODE SWITCHING DWDM NETWORKS 有权
    多模切换DWDM网络中的交通管理方法与设备

    公开(公告)号：US20130094856A1

    公开(公告)日：2013-04-18

    申请号：US13434597

    申请日：2012-03-29

    申请人： Yuhua Chen

    发明人： Yuhua Chen

    IPC分类号： H04J14/02

    CPC分类号： H04J14/02 ,  H04J14/0212 ,  H04J14/0257 ,  H04J14/0267 ,  H04J14/0268 ,  H04J14/0283 ,  H04J14/0284 ,  H04L45/62

    摘要： A Wavelength Division Multiplexing (WDM) multi-mode switching system and method and method provides concurrent switching in various switching modes including, but not limited to, an electronic packet switching (EPS) mode, optical circuit switching (OCS) mode, and optical burst switching (OBS) mode. Edge routers in the WDM multi-mode switching systems may provide a traffic management module that processes incoming data and routes the data for transmission in an electronic packet switching (EPS), optical burst switching (OBS), or optical circuit switching (OCS) modes via a WDM link.

    摘要翻译： 波分多路复用（WDM）多模交换系统及方法和方法提供了各种切换模式的并行切换，包括但不限于电子分组交换（EPS）模式，光电路交换（OCS）模式和光突发 切换（OBS）模式。 WDM多模交换系统中的边缘路由器可以提供流量管理模块，其处理输入数据并将数据路由到电子分组交换（EPS），光突发交换（OBS）或光电路交换（OCS）模式中的传输 通过WDM链接。

    Dense Wavelength Division Multiplexing Multi-Mode Switching Systems and Methods for Concurrent and Dynamic Reconfiguration with Different Switching Modes
    8.
    发明申请
    Dense Wavelength Division Multiplexing Multi-Mode Switching Systems and Methods for Concurrent and Dynamic Reconfiguration with Different Switching Modes 有权
    密集波分复用多模切换系统和方法，用于不同切换模式的并行和动态重配置

    公开(公告)号：US20120148242A1

    公开(公告)日：2012-06-14

    申请号：US13325544

    申请日：2011-12-14

    申请人： Yuhua Chen ,  Wenjing Tang

    发明人： Yuhua Chen ,  Wenjing Tang

    IPC分类号： H04J14/02

    CPC分类号： H04J14/0254 ,  H04J14/0256 ,  H04J14/0272 ,  H04J14/0273 ,  H04J14/0275 ,  H04L45/12 ,  H04W40/02

    摘要： A Wavelength Division Multiplexing (WDM) multi-mode switching system and method and method provides concurrent switching in various switching modes. For example, WDM links may communicate data in various switching modes including, but not limited to, an electronic packet switching (EPS) mode, optical circuit switching (OCS) mode, and optical burst switching (OBS) mode. Edge routers and core routers in the WDM multi-mode switching systems and methods provide switching and processing necessary to handle data provided in the various switching modes. Further, the WDM multi-mode switching systems and methods can also provide dynamic reconfiguration between the various switching modes.

    摘要翻译： 波分多路复用（WDM）多模交换系统及方法和方法提供了各种切换模式的并发切换。 例如，WDM链路可以以各种切换模式传送数据，包括但不限于电子分组交换（EPS）模式，光电路切换（OCS）模式和光突发交换（OBS）模式。 WDM多模切换系统和方法中的边缘路由器和核心路由器提供了处理各种切换模式下提供的数据所需的切换和处理。 此外，WDM多模切换系统和方法还可以提供各种切换模式之间的动态重配置。

    METHODS AND APPARATUS FOR SECURING OPTICAL BURST SWITCHING (OBS) NETWORKS
    9.
    发明申请
    METHODS AND APPARATUS FOR SECURING OPTICAL BURST SWITCHING (OBS) NETWORKS 审中-公开
    用于保护光束交换（OBS）网络的方法和装置

    公开(公告)号：US20090313465A1

    公开(公告)日：2009-12-17

    申请号：US12471972

    申请日：2009-05-26

    申请人： Pramode K. Verma ,  Yuhua Chen

    发明人： Pramode K. Verma ,  Yuhua Chen

    IPC分类号： H04L9/32 ,  H04L29/06 ,  H04L9/08

    CPC分类号： H04L9/0827 ,  H04L63/0428 ,  H04L63/061 ,  H04L63/162 ,  H04Q11/0066 ,  H04Q2011/0079

    摘要： An optical network, having an optical communication link and first and second routers. The first router receives and classifies data, then forms a data burst based on destination. The first router sends an encrypted header and the data burst via the optical link. The second router, at least one hop from the first router, receives, decrypts and authenticates the header. Then, the second router extracts data burst information from the header and determines whether the address of the second router is the destination address for the data burst. If so, the second router receives the data burst and sends data to an appropriate line interface. If not, the second router selects and reserves a wavelength on a second optical link for the data burst. The second router selects an encryption key for the header, encrypts and sends the header, and then routes the data burst to the selected wavelength.

    摘要翻译： 具有光通信链路和第一和第二路由器的光网络。 第一个路由器接收和分类数据，然后形成基于目的地的数据突发。 第一个路由器通过光链路发送加密的报头和数据突发。 第二个路由器，从第一个路由器至少一个跳，接收，解密和认证头。 然后，第二路由器从头部提取数据突发信息，并确定第二路由器的地址是否是数据突发的目的地址。 如果是这样，则第二路由器接收数据突发并将数据发送到适当的线路接口。 如果不是，则第二路由器选择并保留用于数据突发的第二光链路上的波长。 第二个路由器为头部选择加密密钥，加密和发送头，然后将数据突发路由到所选择的波长。

    Component carrier management method and equipment
    10.
    发明授权
    Component carrier management method and equipment 有权
    组件载体管理方法和设备

    公开(公告)号：US08767663B2

    公开(公告)日：2014-07-01

    申请号：US13553530

    申请日：2012-07-19

    申请人： Junren Chang ,  Yajuan Li ,  Shulan Feng ,  Yinghui Yu ,  Yuhua Chen ,  Li Chai

    发明人： Junren Chang ,  Yajuan Li ,  Shulan Feng ,  Yinghui Yu ,  Yuhua Chen ,  Li Chai

    IPC分类号： H04W4/00 ,  H04B7/216

    CPC分类号： H04W24/10 ,  H04L5/001 ,  H04L5/0096 ,  H04L5/0098

    摘要： A component carrier management method which relates to the communication technical field includes determining one or more component carriers that are required to be added into a physical downlink control channel monitoring set; sending a component carrier activation or configuration message to a user equipment to indicate one or more component carriers that are required to be added into the physical downlink control channel monitoring set. Through the technical solutions, the PDCCH monitoring set of the UE may be managed when CCs are activated or configured, so that the UE may maintain the PDCCH monitoring set in real time, implement monitoring on the CCs in the monitoring set, and ensure a service requirement of the UE.

    摘要翻译： 与通信技术领域有关的分量载波管理方法包括确定需要添加到物理下行链路控制信道监视集合中的一个或多个分量载波; 向用户设备发送分量载波激活或配置消息以指示需要被添加到物理下行链路控制信道监视集合中的一个或多个分量载波。 通过技术方案，可以在CC被激活或者配置时对UE的PDCCH监控集进行管理，使得UE可以实时维护PDCCH监控集，对监控集中的CC进行监控，保证业务 要求UE。