-
公开(公告)号：US06833532B1
公开(公告)日：2004-12-21
申请号：US09757856
申请日：2001-01-11
IPC分类号： G02B632
CPC分类号： G02B6/2552 , G02B6/262
摘要： A method and system for fusing an optical fiber lens is compatible with automation. Specifically, the fusing of the fiber lens is controlled in response to a diffraction pattern of light exiting from the fiber lens. This diffraction pattern is indicative of the lens shape and characteristics. Specifically, light is injected into an optical fiber and a diffraction pattern of the light exiting from a fiber lens is detected. The fiber lens is then fused in response to this diffraction pattern.
摘要翻译： 用于融合光纤透镜的方法和系统与自动化兼容。 具体地说，根据从光纤透镜出射的光的衍射图来控制光纤透镜的熔合。 该衍射图案表示透镜的形状和特性。 具体地，将光注入到光纤中，并且检测从光纤透镜出射的光的衍射图案。 然后根据该衍射图案将光纤透镜熔合。
-
公开(公告)号：US06892444B1
公开(公告)日：2005-05-17
申请号：US09667186
申请日：2000-09-21
CPC分类号： G02B6/4226 , G02B6/4225 , G02B6/4227 , G02B6/4237 , G02B6/4238 , Y10T29/49764 , Y10T29/49769 , Y10T29/49771 , Y10T29/49778 , Y10T29/4978 , Y10T29/49895 , Y10T29/49902 , Y10T29/53061 , Y10T29/53083 , Y10T29/53087 , Y10T29/53091 , Y10T29/53222 , Y10T29/53261 , Y10T29/53265
摘要： An optical component manipulation system has two opposed jaws, which can each be independently positioned relative to each other in a coordinate plane to thereby effect the desired positioning of optical components within the larger system. Z-axis rigidity is provided by air-bearings. Laser heating of the jaws is used for solder, or similar heat driven bonding, processes.
-
公开(公告)号：US07076860B2
公开(公告)日：2006-07-18
申请号：US10909010
申请日：2004-07-30
CPC分类号： G02B6/4226 , G02B6/4225 , G02B6/4227 , G02B6/4237 , G02B6/4238 , Y10T29/49764 , Y10T29/49769 , Y10T29/49771 , Y10T29/49778 , Y10T29/4978 , Y10T29/49895 , Y10T29/49902 , Y10T29/53061 , Y10T29/53083 , Y10T29/53087 , Y10T29/53091 , Y10T29/53222 , Y10T29/53261 , Y10T29/53265
摘要： An optical component manipulation system has two opposed jaws, which can each be independently positioned relative to each other in a coordinate plane to thereby effect the desired positioning of optical components within the larger system. Z-axis rigidity is provided by air-bearings. Laser heating of the jaws is used for solder, or similar heat driven bonding, processes.
摘要翻译： 光学部件操纵系统具有两个相对的夹爪，它们各自可以在坐标平面中相对于彼此独立地定位，从而实现在较大系统内的光学部件的期望定位。 Z轴刚度由空气轴承提供。 钳口的激光加热用于焊料或类似的热驱焊接工艺。
-
公开(公告)号：US06488567B1
公开(公告)日：2002-12-03
申请号：US09711029
申请日：2000-11-09
IPC分类号： B24B4900
CPC分类号： B24B49/12 , B24B19/226 , G02B6/25
摘要： An improved system and method for automated fiber polishing overcomes the limitations of conventional systems and methods. In particular, the present invention provides for continuous determination of the quality of the polish during a polishing procedure. An optical signal is transmitted to a fiber tip, and any back-reflected signal is detected and monitored to determine polish quality. In this manner, automated polishing quality assurance is provided in real time.
摘要翻译： 用于自动纤维抛光的改进的系统和方法克服了常规系统和方法的局限性。 特别地，本发明提供了在抛光过程中连续确定抛光剂的质量。 将光学信号传输到光纤尖端，并且检测和监视任何背反射信号以确定抛光质量。 以这种方式，实时提供自动抛光质量保证。
-
公开(公告)号：US20120035528A1
公开(公告)日：2012-02-09
申请号：US13023370
申请日：2011-02-08
申请人： Jonathan R. Coppeta , Kenneth N. Horne , John T. Santini, JR. , John A. Scholl , Gregory J.R. Spooner , Cynthia L. Stevenson , Naveed Shams , Andrew Poutiatine
发明人： Jonathan R. Coppeta , Kenneth N. Horne , John T. Santini, JR. , John A. Scholl , Gregory J.R. Spooner , Cynthia L. Stevenson , Naveed Shams , Andrew Poutiatine
CPC分类号： A61F9/0017 , A61F9/008 , A61K9/0009 , A61K9/0051
摘要： An implantable drug delivery device that uses multiple reservoir elements to contain and release doses of active pharmaceutical ingredients. The device includes a first shell element, which has a first enclosed cavity volume and forms a low-permeability barrier. The first shell element is configured to absorb light irradiation from a laser source, the laser irradiation causing a breach in the first shell element. A first active pharmaceutical ingredient is contained in the first enclosed cavity volume and is released when the first shell element is breached. The device also includes a second shell element, which has a second enclosed cavity volume and also forms a low-permeability barrier. A second active pharmaceutical ingredient is contained in the second enclosed cavity volume. The device also includes an envelope element containing the first and second shell elements.
摘要翻译： 一种可植入药物递送装置，其使用多个储存元件来容纳和释放剂量的活性药物成分。 该装置包括第一壳单元，其具有第一封闭空腔体积并形成低渗透屏障。 第一壳元件被配置为吸收来自激光源的光照射，激光照射引起第一壳元件中的破裂。 第一活性药物成分包含在第一封闭空腔体积中，并且当第一壳元件被破坏时被释放。 该装置还包括第二壳单元，其具有第二封闭空腔体积并且还形成低渗透屏障。 第二活性药物成分包含在第二封闭空腔体积中。 该装置还包括包含第一和第二壳单元的包络元件。
-
公开(公告)号：US08317507B1
公开(公告)日：2012-11-27
申请号：US13469115
申请日：2012-05-11
IPC分类号： B29C43/02
CPC分类号： A61K9/19 , A61J3/10 , A61K9/2072 , A61K9/2095 , B30B11/027
摘要： Methods and systems are provided for making a drug microtablet. The method includes loading a lyophilization capillary channel with a liquid drug solution; lyophilizing the liquid drug solution in the lyophilization capillary channel to produce a lyophilized drug formulation; compressing the lyophilized drug formulation in the lyophilization capillary channel, or in a compression capillary channel, to form a microtablet; and ejecting the microtablet from the lyophilization capillary channel or compression capillary channel. The methods and systems may provide drug microtablets having improved content uniformity and reduced weight variability.
摘要翻译： 提供了制备药物微片的方法和系统。 该方法包括用液体药物溶液加载冻干毛细管通道; 将液体药物溶液冻干在冻干毛细管通道中以产生冻干药物制剂; 在冻干毛细管通道或压缩毛细管通道中压缩冻干药物制剂以形成微片; 并从冻干毛细通道或压缩毛细管通道中喷出微片。 所述方法和系统可以提供具有改善的含量均匀性和降低的重量变异性的药物微片。
-
7.发明授权Multi-opening reservoir devices for controlled release or exposure of reservoir contents 有权用于控制释放或暴露储存器内容物的多开式储存装置公开(公告)号：US08403915B2
公开(公告)日：2013-03-26
申请号：US12581558
申请日：2009-10-19
申请人： John T. Santini, Jr. , Zouhair Sbiaa , Jonathan R. Coppeta , Scott A. Uhland , Norman F. Sheppard, Jr.
发明人： John T. Santini, Jr. , Zouhair Sbiaa , Jonathan R. Coppeta , Scott A. Uhland , Norman F. Sheppard, Jr.
CPC分类号： B01L3/50853 , A61K9/0009 , A61K9/0024 , A61K9/0097 , A61M5/14 , A61M5/14276 , A61N1/05 , B01L2300/0627 , B01L2300/0819 , B01L2400/0677 , Y10T436/25
摘要： Devices, such as medical devices, are provided which include a body portion having at least one reservoir which has two or more openings, the two or more openings being defined in part by a reservoir cap support; reservoir contents, such as a drug formulation or sensor, disposed inside the reservoir; and a reservoir cap which closes off the two or more reservoir openings. The reservoir cap, which can be ruptured, controls release or exposure of the reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor.
摘要翻译： 提供了诸如医疗装置的装置，其包括具有至少一个具有两个或更多个开口的储存器的主体部分，所述两个或多个开口部分地由储存器盖支撑件限定; 设置在储存器内部的储存器内容物，例如药物制剂或传感器; 以及封闭两个或更多储存器开口的储存器盖。 可能破裂的储存盖控制储存器内容物的释放或暴露。 在一个实施例中，该装置是可植入医疗装置，并且提供药物的受控释放或传感器的暴露。
-
公开(公告)号：US07416674B2
公开(公告)日：2008-08-26
申请号：US10007502
申请日：2001-11-08
申请人： Jonathan R. Coppeta
发明人： Jonathan R. Coppeta
IPC分类号： B29D11/00
摘要： A technique for fabricating the required surface shapes for micro optical elements, such as curved micro mirrors and lenses, starts with a simple, binary for example, approximation to the desired surface shape. Then polishing, e.g., chemical mechanical polishing (CMP), is used to form the smooth optical surface. Specifically, starting with a mesa or blind hole, with a mesa profile, a smooth mirror or lens structure is fabricated.
摘要翻译： 用于制造微型光学元件（例如弯曲微型反射镜和透镜）的所需表面形状的技术从简单的二进制开始，例如近似于所需的表面形状。 然后使用抛光，例如化学机械抛光（CMP）来形成光滑的光学表面。 具体来说，从台面形状的台面或盲孔开始，制造平滑的镜面或透镜结构。
-
公开(公告)号：US20120241216A1
公开(公告)日：2012-09-27
申请号：US13488355
申请日：2012-06-04
申请人： Jonathan R. Coppeta , Kurt Shelton , Norman F. Sheppard, JR. , Douglas Snell , Catherine M.B. Santini
发明人： Jonathan R. Coppeta , Kurt Shelton , Norman F. Sheppard, JR. , Douglas Snell , Catherine M.B. Santini
CPC分类号： B81C1/00269 , A61K9/0097 , A61M5/14276 , A61M2205/0244 , A61M2207/00 , B23K20/02 , B33Y80/00 , B81B2201/06 , B81C1/00047 , B81C1/00095 , B81C2203/0109 , B81C2203/019 , B81C2203/038 , F16B4/004 , F16B5/08 , F16B11/004 , H01L23/10 , H01L23/3142 , H01L2224/05001 , H01L2224/05023 , H01L2224/051 , H01L2224/05568 , H01L2224/056 , H01L2224/16237 , H01L2224/81193 , H01L2924/01322 , H01L2924/10253 , H01L2924/1461 , H01L2924/16315 , Y10T403/477 , H01L2924/00 , H01L2924/00014
摘要： Compression cold welding methods, joint structures, and hermetically sealed containment devices are provided. The method includes providing a first substrate having at least one first joint structure which comprises a first joining surface, which surface comprises a first metal; providing a second substrate having at least one second joint structure which comprises a second joining surface, which surface comprises a second metal; and compressing together the at least one first joint structure and the at least one second joint structure to locally deform and shear the joining surfaces at one or more interfaces in an amount effective to form a metal-to-metal bond between the first metal and second metal of the joining surfaces. Overlaps at the joining surfaces are effective to displace surface contaminants and facilitate intimate contact between the joining surfaces without heat input. Hermetically sealed devices can contain drug formulations, biosensors, or MEMS devices.
摘要翻译： 提供压缩冷焊方法，接头结构和密封的密封装置。 该方法包括提供具有至少一个第一接头结构的第一基底，该第一接合结构包括第一接合表面，该表面包括第一金属; 提供具有至少一个第二接头结构的第二基底，所述第二接头结构包括第二接合表面，所述表面包括第二金属; 以及将所述至少一个第一接合结构和所述至少一个第二接头结构压在一起，以在一个或多个界面上局部变形和剪切所述接合表面，所述接合面有效地在所述第一金属和所述第二接头结构之间形成金属与金属之间的接合 金属的接合面。 在接合表面上的重叠有效地移动表面污染物并促进接合表面之间的紧密接触而不需要热量输入。 密封装置可以包含药物制剂，生物传感器或MEMS装置。
-
10.发明授权Multi-cap reservoir devices for controlled release or exposure of reservoir contents 有权用于控制释放或暴露储层内容物的多盖储存装置公开(公告)号：US07604628B2
公开(公告)日：2009-10-20
申请号：US11217799
申请日：2005-09-01
申请人： John T. Santini, Jr. , Zouhair Sbiaa , Jonathan R. Coppeta , Scott A. Uhland , Norman F. Sheppard, Jr.
发明人： John T. Santini, Jr. , Zouhair Sbiaa , Jonathan R. Coppeta , Scott A. Uhland , Norman F. Sheppard, Jr.
IPC分类号： A61K9/22
CPC分类号： B01L3/50853 , A61K9/0009 , A61K9/0024 , A61K9/0097 , A61M5/14 , A61M5/14276 , A61N1/05 , B01L2300/0627 , B01L2300/0819 , B01L2400/0677 , Y10T436/25
摘要： Reservoir-based devices are provided in which an individual reservoir has at least two openings with a support structure therebetween and closed by reservoir caps covering the openings to control release or exposure of reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor. The device includes a substrate; at least one reservoir disposed in the substrate, the reservoir having two or more openings; reservoir contents located in the reservoir; two or more discrete reservoir caps, each reservoir cap sealingly covering at least one of the reservoir openings; and control means for selectively disintegrating or permeabilizing the reservoir caps.
摘要翻译： 提供了一种储存器装置，其中单个储存器具有至少两个开口，其间具有支撑结构，并且通过覆盖开口的储存器盖封闭以控制储存器内容物的释放或暴露。 在一个实施例中，该装置是可植入医疗装置，并且提供药物的受控释放或传感器的暴露。 该装置包括基板; 设置在基板中的至少一个储存器，储存器具有两个或更多个开口; 水库内容位于水库; 两个或更多个分立的储存器盖，每个储存器盖密封地覆盖至少一个储存器开口; 以及用于选择性地使贮存器盖分解或渗透的控制装置。
-
-
-
-
-
-
-
-
-
搜索结果
17 条记录 (耗时 0.033 秒)
