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    Radiused hollow cutting edge needle
    1.
    发明授权
    Radiused hollow cutting edge needle 失效
    半径中空切边针

    公开(公告)号：US5797961A

    公开(公告)日：1998-08-25

    申请号：US916964

    申请日：1997-08-19

    申请人： Daniel J. Smith ,  Carl Gucker ,  Zivko Elik ,  Paul Parisi ,  Randolph Ruetsch ,  William McJames ,  Emil Richard Skula

    发明人： Daniel J. Smith ,  Carl Gucker ,  Zivko Elik ,  Paul Parisi ,  Randolph Ruetsch ,  William McJames ,  Emil Richard Skula

    IPC分类号： A61B17/06

    CPC分类号： A61B17/06066 ,  A61B17/06004

    摘要： A cutting edge surgical suture needle. The suture needle is an elongated member having a proximal suture mounting end and a distal piercing tip. The distal section of the needle has a cross-section having a top side with opposed edges. The cross-section also has opposed curved concave lateral sides having top edges and bottom edges. The top edges of the concave sides and the opposed sides of the top side are coextensive and form cutting edges. The bottom edges of the opposed concave sides are coextensive and form a bottom cutting edge.

    摘要翻译： 尖端手术缝合针。 缝合针是具有近端缝线安装端和远端穿刺尖端的细长构件。 针的远端部分具有具有相对边缘的顶侧的横截面。 横截面也具有相对的具有顶部边缘和底部边缘的弯曲凹入侧面。 凹面的顶边和顶侧的相对侧共同延伸并形成切割边。 相对的凹面的底边共同延伸并形成底切割边。

    Anchorage devices comprising an active pharmaceutical ingredient
    6.
    发明授权
    Anchorage devices comprising an active pharmaceutical ingredient 有权
    包含活性药物成分的锚定装置

    公开(公告)号：US09585988B2

    公开(公告)日：2017-03-07

    申请号：US13293816

    申请日：2011-11-10

    申请人： William McJames ,  Frank Do ,  Satish Pulapura ,  Qing Ge

    发明人： William McJames ,  Frank Do ,  Satish Pulapura ,  Qing Ge

    IPC分类号： A61N1/05 ,  A61L31/08 ,  A61L31/10 ,  A61L31/16

    CPC分类号： A61L31/08 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/602 ,  A61N1/059

    摘要： An anchorage device comprising a mesh substrate coupled to an implantable medical device is disclosed, where the mesh substrate has a coating comprising a polymer, and the mesh further comprises at least one active pharmaceutical ingredient. The active pharmaceutical agent is designed to elute from the mesh over time. The mesh substrate can be configured to reduce the mass of the anchorage device such that tissue in-growth and/or scar tissue formation at the treatment site is reduced. In some embodiments, the mesh substrate can be formed with a mesh having a low areal density. In some embodiments, the mesh substrate can include one or more apertures or pores to reduce the mass of the substrate.

    摘要翻译： 公开了一种锚固装置，其包括联接到可植入医疗装置的网状基底，其中网状基底具有包含聚合物的涂层，并且网状物还包含至少一种活性药物成分。 活性药剂被设计成随时间从网筛中洗脱。 网状基底可以被配置为减小锚固装置的质量，使得在治疗部位的组织生长和/或瘢痕组织形成减少。 在一些实施例中，网状基底可以形成有具有低面密度的网。 在一些实施例中，网状基底可以包括一个或多个孔或孔以减小基底的质量。

    Mesh pouches for implantable medical devices
    9.
    发明授权
    Mesh pouches for implantable medical devices 有权
    用于可植入医疗器械的网袋

    公开(公告)号：US08591531B2

    公开(公告)日：2013-11-26

    申请号：US11936054

    申请日：2007-11-06

    申请人： Fatima Buevich ,  Arikha Moses ,  Frank Do ,  William McJames ,  William Edelman ,  Mason Diamond ,  Satish Pulapura

    发明人： Fatima Buevich ,  Arikha Moses ,  Frank Do ,  William McJames ,  William Edelman ,  Mason Diamond ,  Satish Pulapura

    IPC分类号： A61B17/08 ,  B65D69/00

    CPC分类号： A61L31/10 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2090/0815 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00 ,  A61N1/375

    摘要： Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The pouches of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use, and, optionally, include one or more drugs in the polymer matrix of the coating to provide prophylactic effects and/or alleviate side effects or complications associated with the surgery or implantation of the CRM or other implantable medical device.

    摘要翻译： 描述形成袋的可生物降解的聚合物涂覆的手术网与心律管理装置（CRM）和其他可植入医疗装置一起使用。 这样的网状物形成为能够包围，围绕和/或保持心律管理装置或其它可植入医疗装置的容器，例如袋或其它覆盖物，以确保其在适当位置，抑制或减少细菌生长， 在CRM或其他可植入医疗设备上或周围提供疼痛缓解和/或抑制瘢痕形成或纤维化。 优选的实施方案包括涂覆有一种或多种可生物降解的聚合物的手术网袋，其可以通过涂覆网的细丝或纤维来暂时固定那些丝或纤维的接触点和/或通过增加网的刚度而充当硬化剂 至少是其原始刚度的1.1倍。 本发明的小袋还可以缓解与其植入，插入或手术使用相关的各种术后并发症，并且任选地在包衣的聚合物基质中包括一种或多种药物以提供预防效果和/或缓解侧 与手术或植入CRM或其他可植入医疗器械相关的影响或并发症。