公开(公告)号：US20070255206A1

公开(公告)日：2007-11-01

申请号：US10595329

申请日：2004-10-14

Applicant: Darrell Reneker ,  Daniel Smith ,  Erik Andersen

Inventor： Darrell Reneker ,  Daniel Smith ,  Erik Andersen

IPC: A61L29/14

CPC classification number: A61L31/10 ,  A61B17/12022 ,  A61B17/1215 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12186 ,  A61B2017/00004 ,  A61B2017/00893 ,  A61F2/82 ,  A61F2250/0067 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/00 ,  A61L2400/12 ,  A61M25/0043 ,  A61M25/09 ,  C08L79/02

Abstract: An expandable balloon for use in angioplasty procedures comprises a balloon having an outer surface layer, the outer surface layer being made from electrospun nanofibers and incorporating at least one pharmaceutically active substance, such as nitric oxide (NO). The outer surface layer may be formed on a separate flexible tubular member or sock, which is slipped over the balloon. An acidic agent, such as ascorbic acid, may be included in the balloon for enhancing NO release. A method of treating cell disorders in tubular structures of a living being comprises the steps of placing a coated balloon at a treatment site within the tubular structures, expanding the balloon at the treatment site, and releasing the pharmaceutically active substance at the treatment site. Optionally, a stent may be crimped onto the balloon prior to insertion of the balloon and stent into the tubular structures of the living being.

Abstract translation: 用于血管成形术程序的可膨胀气囊包括具有外表面层的球囊，外表面层由静电纺丝纳米纤维制成并且并入至少一种药物活性物质，例如一氧化氮（NO）。 外表面层可以形成在单独的柔性管状构件或袜子上，该弹性管状构件或袜子滑过气球。 气球中可以含有抗坏血酸等酸性剂，以增强NO释放。 一种治疗生物体管状结构中的细胞病症的方法包括以下步骤：将涂覆的球囊放置在管状结构内的治疗部位，使治疗部位膨胀，并在治疗部位释放药物活性物质。 任选地，在将球囊和支架插入生命体的管状结构之前，可以将支架卷曲到球囊上。

公开(公告)号：US20070207179A1

公开(公告)日：2007-09-06

申请号：US10595339

申请日：2004-10-14

Applicant: Erik Andersen ,  Daniel Smith ,  Darrell Reneker

Inventor： Erik Andersen ,  Daniel Smith ,  Darrell Reneker

IPC: A61F2/06 ,  A61K31/66 ,  A61L27/00 ,  A61M5/00

CPC classification number: A61L31/10 ,  A61B17/12022 ,  A61B17/1215 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12186 ,  A61B2017/00004 ,  A61B2017/00893 ,  A61F2/82 ,  A61F2250/0067 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/00 ,  A61L2400/12 ,  A61M25/0043 ,  A61M25/09 ,  C08L79/02

Abstract: A medical device, such as a guide wire, an embolization device, or a guide shaft for a micro catheter, comprises a solid and/or non-expandable core member made from e.g. metal, such as tantalum, and an outer surface layer, which is formed by electrospun nanofibers. The outer surface layer may incorporate a pharmaceutically active substance, such as a nitric oxide (NO) donor for release in the vascular or neurovascular system of a living being. The NO donor may be incorporated in a polymer, such as a polymeric linear poly(ethylenimine) diazeniumdiolate.

Abstract translation: 用于微导管的医疗装置，例如导丝，栓塞装置或导向轴，包括由例如导管制成的固体和/或不可膨胀的芯构件。 金属，例如钽，以及由静电纺丝纳米纤维形成的外表面层。 外表面层可以并入药物活性物质，例如一氧化氮（NO）供体，用于在生命的血管或神经血管系统中释放。 可以将NO供体掺入聚合物如聚合物线性聚（亚乙基亚胺）二氮烯鎓二醇酯中。

公开(公告)号：US08392706B2

公开(公告)日：2013-03-05

申请号：US12626517

申请日：2009-11-25

Applicant: Elliot Spencer ,  Samuel J. Baker ,  Erik Andersen

Inventor： Elliot Spencer ,  Samuel J. Baker ,  Erik Andersen

IPC: G06F21/00

CPC classification number: G06F21/6218

Abstract: A method and system for searching and collecting electronically stored information are described. Consistent with an embodiment of the invention, configuration and execution of a search are separated in time and location. For example, a search configuration application executing at a first computer system is utilized to generate a search configuration file, which controls the operation of a search agent when the search agent is executing at a target computer system and performing a search of storage devices act of the target computer system. Encryption is utilized to prevent unauthorized access to the search configuration file as well as the search results file generated by the search agent.

Abstract translation: 描述了一种用于搜索和收集电子存储信息的方法和系统。 与本发明的实施例一致，搜索的配置和执行在时间和位置上分离。 例如，在第一计算机系统中执行的搜索配置应用程序被用于生成搜索配置文件，该搜索配置文件控制搜索代理在目标计算机系统上执行时的操作，并执行对存储设备的搜索 目标计算机系统。 利用加密来防止未经授权的访问搜索配置文件以及搜索代理产生的搜索结果文件。

公开(公告)号：US20100138653A1

公开(公告)日：2010-06-03

申请号：US12626517

申请日：2009-11-25

Applicant: Elliot Spencer ,  Samuel J. Baker ,  Erik Andersen

Inventor： Elliot Spencer ,  Samuel J. Baker ,  Erik Andersen

IPC: H04L9/00 ,  G06F21/00 ,  G06F17/30

CPC classification number: G06F21/6218

Abstract: A method and system for searching and collecting electronically stored information are described. Consistent with an embodiment of the invention, configuration and execution of a search are separated in time and location. For example, a search configuration application executing at a first computer system is utilized to generate a search configuration file, which controls the operation of a search agent when the search agent is executing at a target computer system and performing a search of storage devices act of the target computer system. Encryption is utilized to prevent unauthorized access to the search configuration file as well as the search results file generated by the search agent.

Abstract translation: 描述了一种用于搜索和收集电子存储信息的方法和系统。 与本发明的实施例一致，搜索的配置和执行在时间和位置上分离。 例如，在第一计算机系统中执行的搜索配置应用程序被用于生成搜索配置文件，该搜索配置文件控制搜索代理在目标计算机系统上执行时的操作，并执行对存储设备的搜索 目标计算机系统。 利用加密来防止未经授权的访问搜索配置文件以及搜索代理产生的搜索结果文件。

公开(公告)号：US20070255998A1

公开(公告)日：2007-11-01

申请号：US11819512

申请日：2007-06-27

Applicant: Weitong Chuang ,  Erik Andersen

Inventor： Weitong Chuang ,  Erik Andersen

IPC: G11C29/00

CPC classification number: H04L49/552 ,  H04L49/206 ,  H04L49/351

Abstract: A network device for minimizing latency and correcting errors associated with information transmitted from an external memory device. The network device includes a management unit for requesting information stored on at least one external memory device. The network device also includes a command unit for transmitting a request from the management unit to the external memory device. The command unit maintain at least one counter that is associated with current requests and compares the at least one counter to at least one predefined threshold in order to throttle the management unit when the at least one counter exceeds the at least one threshold. The network device further includes means for aligning information from the at least one external memory device with information transmitted from the command unit to the management unit and for ensuring that aligned information is accurate.

公开(公告)号：US20070073242A1

公开(公告)日：2007-03-29

申请号：US10560806

申请日：2004-06-17

Applicant: Erik Andersen ,  Finn Birk Pedersen

Inventor： Erik Andersen ,  Finn Birk Pedersen

IPC: A61M5/178

CPC classification number: A61M39/0693 ,  A61M2205/583

Abstract: A closure for a valve (128) of a connector (100) of a haemostatic valve assembly with a longitudinally extending main section (114) having a longitudinally extending, through-going passage (110; 112) with the valve (128) at a proximal end of the connector. The closure comprises a closure member (130), a face (156) of which abuts a proximal end surface (152) of the main section (114), one of said face and end surface (152; 156) being provided with a protrusion (158) for engaging a corresponding indentation (154) provided in the other one of said face and said end surface (152; 156), so as to provide a liquid tight seal near an outer periphery of the passage (110; 112) at a proximal end thereof.

Abstract translation: 用于止血阀组件的连接器（100）的阀门（128）的封闭件，其具有纵向延伸的主要部分（114），所述主要部分具有纵向延伸的贯穿通道（110; 112），阀门（128）位于 连接器的近端。 闭合件包括封闭构件（130），其表面（156）邻接主区段（114）的近端表面（152），所述面和端表面（152; 156）中的一个设置有突起 （158），用于接合设置在所述面和所述端面（152; 156）中的另一个中的相应的凹口（154），以便在所述通道（110; 112）的外周附近提供液密密封 其近端。

公开(公告)号：US20060293743A1

公开(公告)日：2006-12-28

申请号：US10531327

申请日：2003-10-14

Applicant: Erik Andersen ,  Ning Wen

Inventor： Erik Andersen ,  Ning Wen

IPC: A61F2/06

CPC classification number: A61F2/07 ,  A61F2/91 ,  A61F2/915

Abstract: A stent assembly comprises an expandable tubular stent (21), an external surface of which is provided with a fabric (5) which may constitute a reservoir to hold drugs to be released in the intravascular system of a living. The fabric (5) may be made from a filamentary material, such as multifilament yarn (6). Electrospinning of nanofibers of, e.g., polymer may be employed for manufacturing the fabric. The stent may comprise an assembly of radially expandable, tubular elements (1) aligned along a common longitudinal axis and successively joined together in pairs by respective sets of linking members (4), e.g. forming a zigzag corrugation. The stent may be crimped onto a balloon.

Abstract translation: 支架组件包括可扩张的管状支架（21），其外表面设置有织物（5），所述织物可以构成储存器以容纳待释放的活体血管内系统中的药物。 织物（5）可以由丝状材料制成，例如复丝纱线（6）。 例如聚合物的纳米纤维的静电纺丝可用于制造织物。 支架可以包括沿着共同的纵向轴线对准的可径向扩张的管状元件（1）的组件，并且通过相应的一组连接构件（4）成对连续地连接在一起。 形成锯齿形波纹。 支架可以卷曲到气球上。

公开(公告)号：US20060129178A1

公开(公告)日：2006-06-15

申请号：US11345098

申请日：2006-01-31

Applicant: Nikolaus Reifart ,  Erik Andersen ,  John Abele ,  Sandra Tartaglino ,  Timothy Wheeler

Inventor： Nikolaus Reifart ,  Erik Andersen ,  John Abele ,  Sandra Tartaglino ,  Timothy Wheeler

IPC: A61M29/00

CPC classification number: A61M25/104 ,  A61M2025/0063 ,  A61M2025/0183 ,  A61M2025/1079

Abstract: A stiffenable balloon catheter assembly capable of being converted from an “over-the-wire” mode with respect to a quidewire extending therethrough to a “rapid-exchange” mode with respect to a guidewire extending therethrough, and vice versa. The catheter has a plurality of lumens, one lumen however, having a side opening with an obstructable galp, the orientation of which, determines the utilization “mode” of the catheter assembly. Stiffening stylets may be adjustably locked into the lumens, depending upon the “mode”, to control the stiffness of the catheter assembly during its utilization within a patient.

Abstract translation: 相对于延伸穿过其中的导线的“快速交换”模式，能够从“线上”模式转换成可以将“线上”模式转换成“快速交换”模式的可加强气球导管组件，反之亦然。 导管具有多个管腔，但是，一个管腔具有一个具有阻塞性隆起的侧开口，其取向决定了导管组件的利用“模式”。 取决于“模式”，加强样式可以可调节地锁定到腔中，以在患者体内使用期间控制导管组件的刚度。

公开(公告)号：US06990564B2

公开(公告)日：2006-01-24

申请号：US10354637

申请日：2003-01-29

Applicant: Erik Andersen

Inventor： Erik Andersen

IPC: G06F12/02

CPC classification number: H04L49/9047 ,  H04L49/90

Abstract: A method and apparatus for combining cost effectiveness of data signal ports sharing a common memory storage device with reliable data signal communication of data signal ports each having a dedicated memory storage device. In one embodiment, data signals are received at a number of data signal ports of a data signal communication platform. A data signal bandwidth capability of a memory storage device of the data communication platform is determined. Once the data signal bandwidth capability of the memory storage device is determined, the memory storage device is segmented to improve utilization of the data signal bandwidth capability. As a result, cost effectiveness of data signal ports sharing a common memory storage device and reliability of data signal communication of data signal ports each having a dedicated memory storage device is combined.

公开(公告)号：US06505654B1

公开(公告)日：2003-01-14

申请号：US09577540

申请日：2000-10-20

Applicant: Erik Andersen ,  Ernst Peter Strecker

Inventor： Erik Andersen ,  Ernst Peter Strecker

IPC: B21F4500

CPC classification number: A61F2/90 ,  A61F2/0077 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/046 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2250/0039 ,  D04B1/225 ,  D10B2509/06 ,  Y10S623/902

Abstract: A stent for reinforcement of the lumen of a peristaltic organ is formed by knitting preferably a nitinol wire into a pattern of overlapping loops selected such that from a relaxed state each row of loops may shift axially relative to and independently of the rows on either side. This local lengthening and shortening accommodate peristalsis of the organ without migrating within the organ. A stent is also shown which comprises two resilient cylindrical mesh layers and a semi-permeable compliant membrane such as expanded polytetrafluoroethylene, sandwiched between. The two mesh layers may be knit of a flexible filament, and the knit may be configured so that the stent can adapt to peristalsis of the body lumen. A method is also shown of manufacturing a delivery system for a resilient tubular device such as a stent so that the device can be inserted into the body in a substantially reduced diameter. The method uses a confining block having a bore and a slot leading into the bore. The tubular device is pinched and inserted into the bore and the slot, two mandrels are inserted into the bore, one inside the device and one outside and the mandrels are revolved about each other to roll the device on itself.