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公开(公告)号：US6047218A
公开(公告)日：2000-04-04
申请号：US298198
申请日：1999-04-23
申请人： James G. Whayne , David K. Swanson , Dorin Panescu , David McGee , Harm TenHoff
发明人： James G. Whayne , David K. Swanson , Dorin Panescu , David McGee , Harm TenHoff
IPC分类号： A61B1/005 , A61B1/01 , A61B1/04 , A61B1/12 , A61B5/042 , A61B5/0456 , A61B18/14 , A61N1/02 , A61B8/00
CPC分类号： A61B8/543 , A61B1/00082 , A61B1/00085 , A61B1/0016 , A61B1/00183 , A61B18/1492 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B1/0051 , A61B2017/003 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00839 , A61B2018/1861 , A61B2090/3782 , A61B2562/0209 , A61B2562/043 , A61B5/0456 , A61B5/7285 , A61B6/541
摘要： An imaging element characterizes tissue morphology by analyzing perfusion patterns of a contrast media in tissue visualized by the imaging element, to identify infarcted tissue. In a preferred implementation, a catheter tube introduced into a heart region carries the imaging element, as well as a support structure spaced from the imaging element, which contacts endocardial tissue. The imaging element is moved as the imaging element visualizes tissue. A selected electrical event is sensed in surrounding myocardial tissue, which regulates movement of the imaging element. The support element stabilizes the moving imaging element as it visualizes tissue, providing resistance to dislodgment or disorientation despite the presence of dynamic forces.
摘要翻译： 成像元件通过分析由成像元件可视化的组织中的造影剂的灌注图案来表征组织形态，以鉴定梗塞的组织。 在优选的实施方案中，引入心脏区域的导管管携带成像元件以及与成像元件间隔开的与心内膜组织接触的支撑结构。 当成像元件可视化组织时，成像元件移动。 在周围的心肌组织中感测到选择的电事件，其调节成像元件的运动。 支撑元件使运动的成像元件稳定，因为它可视化组织，提供抵抗移动或定向障碍，尽管存在动态力。
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公开(公告)号：US5752518A
公开(公告)日：1998-05-19
申请号：US738822
申请日：1996-10-28
申请人： David McGee , David K. Swanson , Harm TenHoff , Dorin Panescu , James G. Whayne
发明人： David McGee , David K. Swanson , Harm TenHoff , Dorin Panescu , James G. Whayne
IPC分类号： A61B5/0408 , A61B1/00 , A61B5/00 , A61B5/0402 , A61B5/0478 , A61B5/0492 , A61B8/12 , A61B18/12 , A61B18/14 , A61M25/00 , A61B8/00
CPC分类号： A61B8/12 , A61B18/1492 , A61B8/4461 , A61B2018/00208 , A61B2018/00214 , A61B2018/1861 , A61B5/0066 , A61B5/0084 , A61B5/7285 , A61B6/541 , A61B8/4488 , A61B8/543
摘要： An imaging system for visualizing an interior body region comprises a catheter tube having a proximal end and a distal end adapted for introduction into the interior body region. The distal end carries an element that forms a three-dimensional support structure for contacting peripheral tissue in the interior body region. The three-dimensional support structure has an open interior. The distal end also carries an imaging element for visualizing the interior body region. The three-dimensional support structure peripherally surrounds the imaging element, thereby keeping peripheral tissue from contacting the imaging element. A steering mechanism on the proximal end of the catheter tube moves the imaging element within the open interior of the three-dimensional support structure. The system provides a stable platform through which accurate displays of interior body images can be created for viewing and analysis by the physician, so the appropriate treatment or therapy can be prescribed.
摘要翻译： 用于可视化内部身体区域的成像系统包括具有适于引入到内部身体区域中的近端和远端的导管。 远端携带形成用于接触内部身体区域中的外周组织的三维支撑结构的元件。 三维支撑结构具有开放的内部结构。 远端还携带用于使内部身体区域可视化的成像元件。 三维支撑结构外围地围绕成像元件，从而保持外围组织不接触成像元件。 在导管管的近端上的转向机构将成像元件移动到三维支撑结构的开放内部。 该系统提供了一个稳定的平台，可以通过该平台创建内部身体图像的精确显示，以供医生观察和分析，因此可以规定适当的治疗或治疗。
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3.发明授权Systems for visualizing interior tissue regions including an actuator to move imaging element 失效用于可视化内部组织区域的系统，包括用于移动成像元件的致动器
公开(公告)号：US5908445A
公开(公告)日：1999-06-01
申请号：US738817
申请日：1996-10-28
申请人： James G. Whayne , David K. Swanson , Dorin Panescu , David McGee , Harm TenHoff
发明人： James G. Whayne , David K. Swanson , Dorin Panescu , David McGee , Harm TenHoff
IPC分类号： A61B1/005 , A61B1/01 , A61B1/04 , A61B1/12 , A61B5/042 , A61B5/0456 , A61B18/14 , A61N1/02 , A61B8/00
CPC分类号： A61B8/543 , A61B1/00082 , A61B1/00085 , A61B1/0016 , A61B1/00183 , A61B18/1492 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B1/0051 , A61B2017/003 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00839 , A61B2018/1861 , A61B2090/3782 , A61B2562/0209 , A61B2562/043 , A61B5/0456 , A61B5/7285 , A61B6/541
摘要： An imaging element characterizes tissue morphology by analyzing perfusion patterns of a contrast media in tissue visualized by the imaging element, to identify infarcted tissue. In a preferred implementation, a catheter tube introduced into a heart region carries the imaging element, as well as a support structure spaced from the imaging element, which contacts endocardial tissue. The imaging element is moved as the imaging element visualizes tissue. A selected electrical event is sensed in surrounding myocardial tissue, which regulates movement of the imaging element. The support element stabilizes the moving imaging element as it visualizes tissue, providing resistance to dislodgment or disorientation despite the presence of dynamic forces.
摘要翻译： 成像元件通过分析由成像元件可视化的组织中的造影剂的灌注图案来表征组织形态，以鉴定梗塞的组织。 在优选的实施方案中，引入心脏区域的导管管携带成像元件以及与成像元件间隔开的与心内膜组织接触的支撑结构。 当成像元件可视化组织时，成像元件移动。 在周围的心肌组织中感测到选择的电事件，其调节成像元件的运动。 支撑元件使运动的成像元件稳定，因为它可视化组织，提供抵抗移动或定向障碍，尽管存在动态力。
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4.发明授权Systems and methods for visualizing interior tissue regions using expandable imaging structures 失效使用可扩展成像结构可视化内部组织区域的系统和方法
公开(公告)号：US5848969A
公开(公告)日：1998-12-15
申请号：US736827
申请日：1996-10-28
申请人： Dorin Panescu , James G. Whayne , David K. Swanson , David McGee , Harm TenHoff
发明人： Dorin Panescu , James G. Whayne , David K. Swanson , David McGee , Harm TenHoff
CPC分类号： A61B5/053 , A61B1/32 , A61B5/0084 , A61B5/0422 , A61B5/0538 , A61B5/6853 , A61B5/6858 , A61B8/12 , A61B8/481 , A61B2090/3782 , A61B2562/0209 , A61B2562/043 , A61B2562/046 , A61B5/7285 , A61B6/541 , A61B8/445 , A61B8/543
摘要： An imaging structure has a periphery adapted to selectively assume an expanded geometry and a collapsed geometry. The periphery of the imaging structure carries an array of spaced apart ultrasound transducers.
摘要翻译： 成像结构具有适于选择性地假设展开的几何形状和折叠的几何形状的周边。 成像结构的周边带有间隔开的超声换能器阵列。
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公开(公告)号：US06658279B2
公开(公告)日：2003-12-02
申请号：US09993826
申请日：2001-11-05
申请人： David K. Swanson , David McGee , Dorin Panescu , James G. Whayne , Harm TenHoff
发明人： David K. Swanson , David McGee , Dorin Panescu , James G. Whayne , Harm TenHoff
IPC分类号： A61B500
CPC分类号： A61B8/12 , A61B5/0066 , A61B5/0084 , A61B5/042 , A61B5/4836 , A61B5/6852 , A61B5/6859 , A61B5/7285 , A61B6/541 , A61B8/445 , A61B8/54 , A61B8/543
摘要： A catheter for ablating and imaging tissue includes a porous electrode structure comprising an interior region for receiving a conductive medium, an elongate tube having a distal tube end that extends within the interior region, and an ultrasonic transducer assembly housed within the distal tube end.
摘要翻译： 用于烧蚀和成像组织的导管包括多孔电极结构，其包括用于接收导电介质的内部区域，具有在内部区域内延伸的远端管端的细长管和容纳在远端管端内的超声换能器组件。
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6.发明授权Systems and methods for visualizing tissue during diagnostic or therapeutic procedures 有权在诊断或治疗过程中可视化组织的系统和方法公开(公告)号：US06522913B2
公开(公告)日：2003-02-18
申请号：US09301020
申请日：1999-04-28
申请人： David K. Swanson , David McGee , Dorin Panescu , James G. Whayne , Harm TenHoff
发明人： David K. Swanson , David McGee , Dorin Panescu , James G. Whayne , Harm TenHoff
IPC分类号： A61B500
CPC分类号： A61B8/12 , A61B5/0066 , A61B5/0084 , A61B5/042 , A61B5/4836 , A61B5/6852 , A61B5/6859 , A61B5/7285 , A61B6/541 , A61B8/445 , A61B8/54 , A61B8/543
摘要： A catheter tube carries an imaging element for visualizing tissue. The catheter tube also carries a support structure, which extends beyond the imaging element for contacting surrounding tissue away from the imaging elements, the imaging element being movable with the support structure. The support element stabilizes the imaging element, while the imaging element visualizes tissue in the interior body region. The support structure also carries a diagnostic or therapeutic component to contact surrounding tissue.
摘要翻译： 导管管携带用于使组织可视化的成像元件。 导管还具有延伸超过成像元件的支撑结构，用于使周围组织远离成像元件，成像元件可与支撑结构一起移动。 支撑元件稳定成像元件，而成像元件可视化内部身体区域中的组织。 支撑结构还携带用于接触周围组织的诊断或治疗部件。
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7.发明授权Systems and methods for visualizing tissue during diagnostic or therapeutic procedures 失效在诊断或治疗过程中可视化组织的系统和方法
公开(公告)号：US5904651A
公开(公告)日：1999-05-18
申请号：US739504
申请日：1996-10-28
申请人： David K. Swanson , David McGee , Dorin Panescu , James G. Whayne , Harm TenHoff
发明人： David K. Swanson , David McGee , Dorin Panescu , James G. Whayne , Harm TenHoff
CPC分类号： A61B8/12 , A61B5/0084 , A61B5/6852 , A61B8/445 , A61B8/54 , A61B8/543 , A61B5/0066 , A61B5/7285 , A61B6/541
摘要： A catheter tube carries an imaging element for visualizing tissue. The catheter tube also carries a support structure, which extends beyond the imaging element for contacting surrounding tissue away from the imaging element. The support element stabilizes the imaging element, while the imaging element visualizes tissue in the interior body region. The support structure also carries a diagnostic or therapeutic component to contact surrounding tissue.
摘要翻译： 导管管携带用于使组织可视化的成像元件。 导管还具有延伸超过成像元件的支撑结构，用于使周围组织远离成像元件。 支撑元件稳定成像元件，而成像元件可视化内部身体区域中的组织。 支撑结构还携带用于接触周围组织的诊断或治疗部件。
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公开(公告)号：US06824515B2
公开(公告)日：2004-11-30
申请号：US10305256
申请日：2002-11-25
IPC分类号： A61B812
CPC分类号： A61B18/1492 , A61B2017/00106 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/124 , A61B2090/065 , A61B2090/3784 , A61N7/02 , A61N2007/0078
摘要： The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.
摘要翻译： 本发明提供超声引导消融导管及其使用方法。 在一个实施例中，组织消融装置（2）包括具有近端（14）和远端（12）端部的柔性细长体（12）。 多个间隔开的电极（24）在远端附近可操作地附接到柔性体。 多个换能器元件（28）设置在至少一些电极之间。 传感器帮助医师确定消融元件是否与要消融的组织接触。
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公开(公告)号：US06206831B1
公开(公告)日：2001-03-27
申请号：US09227281
申请日：1999-01-06
IPC分类号： A61B812
CPC分类号： A61B18/1492 , A61B2017/00106 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/124 , A61B2090/065 , A61B2090/3784 , A61N7/02 , A61N2007/0078
摘要： The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.
摘要翻译： 本发明提供超声引导消融导管及其使用方法。 在一个实施例中，组织消融装置（2）包括具有近端（14）和远端（12）端部的柔性细长体（12）。 多个间隔开的电极（24）在远端附近可操作地附接到柔性体。 多个换能器元件（28）设置在至少一些电极之间。 传感器帮助医师确定消融元件是否与要消融的组织接触。
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公开(公告)号：US06508765B2
公开(公告)日：2003-01-21
申请号：US09750439
申请日：2000-12-28
IPC分类号： A61B800
CPC分类号： A61B18/1492 , A61B2017/00106 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/124 , A61B2090/065 , A61B2090/3784 , A61N7/02 , A61N2007/0078
摘要： The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.
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