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公开(公告)号：US07776559B2
公开(公告)日：2010-08-17
申请号：US10762784
申请日：2004-01-22
Applicant: Winthrop D. Childers , David Tyvoll
Inventor： Winthrop D. Childers , David Tyvoll
IPC: G01N33/567
CPC classification number: A61B5/14532 , A61B5/1486 , A61B2562/085 , G01N33/48771
Abstract: A disposable blood test device comprises a substrate configured for carrying a chemical reagent and circuitry formed on the substrate. The circuitry comprises a sensor portion associated with the chemical reagent to enable measurement of at least one of a presence and a concentration of a blood analyte, and an information storage portion configured to store information indicative of a property of the chemical reagent.
Abstract translation: 一次性血液检查装置包括被配置为承载形成在基底上的化学试剂和电路的基底。 电路包括与化学试剂相关联的传感器部分，以能够测量血液分析物的存在和浓度中的至少一种，以及配置为存储指示化学试剂的性质的信息的信息存储部分。
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公开(公告)号：US07389879B2
公开(公告)日：2008-06-24
申请号：US10763112
申请日：2004-01-21
Applicant: David Tyvoll , Winthrop D. Childers , Paul Crivelli
Inventor： David Tyvoll , Winthrop D. Childers , Paul Crivelli
IPC: B07C5/02
CPC classification number: G01N15/1459 , G01N15/1056 , G01N2015/1081 , G01N2015/149 , Y10S209/906
Abstract: A device for sorting particles. The device may include a channel structure that defines a channel having an inlet and first and second outlets. The device also may include first and second transport mechanisms. The first transport mechanism may be configured to create a particle stream of first particles and one or more second particles. Each particle may move along the channel from the inlet toward the first outlet and may be disposed in a fluid supported by the channel structure. The second transport mechanism may be configured to be pulse-activated to selectively move at least one of the second particles from the particle stream and toward the second outlet.
Abstract translation: 用于分选颗粒的装置。 该装置可以包括限定具有入口和第一和第二出口的通道的通道结构。 该装置还可以包括第一和第二传送机构。 第一输送机构可以被配置成产生第一颗粒和一个或多个第二颗粒的颗粒物流。 每个颗粒可以沿着通道从入口移动到第一出口，并且可以设置在由通道结构支撑的流体中。 第二传送机构可以被配置为被脉冲激活以选择性地将颗粒流中的至少一个第二颗粒移动到第二出口。
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公开(公告)号：US07217542B2
公开(公告)日：2007-05-15
申请号：US10286104
申请日：2002-10-31
Applicant: David Tyvoll , Winthrop D. Childers
Inventor： David Tyvoll , Winthrop D. Childers
CPC classification number: B01L3/50273 , B01L3/502715 , B01L7/52 , B01L2200/027 , B01L2200/0647 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0663 , B01L2300/0809 , B01L2300/087 , B01L2300/0874 , B01L2300/1827 , B01L2400/0415 , B01L2400/0487 , B01L2400/0633
Abstract: A system, including methods and apparatus, for microfluidic analysis of a nucleic acid target in a nucleic acid mixture. The system includes a method to preselect the target from the mixture before amplification. Preselection enriches the mixture for the target by retaining the target on a target-selective receptor and then removing unretained non-target nucleic acids. The preselected target then may be amplified from the enriched mixture and assayed. Devices configured to carry out the method are also disclosed.
Abstract translation: 一种用于核酸混合物中核酸靶的微流体分析的系统，包括方法和装置。 该系统包括在扩增前从混合物中预选靶的方法。 预选通过将靶标保留在靶选择性受体上，然后除去未保留的非靶核酸，从而丰富目的物的混合物。 然后可以从富集的混合物中扩增预选靶，并进行测定。 还公开了被配置为执行该方法的设备。
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公开(公告)号：US07112433B2
公开(公告)日：2006-09-26
申请号：US10423166
申请日：2003-04-24
Applicant: David Tyvoll , Winthrop D. Childers
Inventor： David Tyvoll , Winthrop D. Childers
IPC: C12M1/34
CPC classification number: G01N33/502 , G01N33/48728 , G01N33/5008 , G01N33/54366
Abstract: A biochip device for electrical analysis of biological membranes. The device may include a substrate assembly defining an array of apertures and including thin-film devices configured to sense an electrical property of biological membranes that seal the apertures. The device also may include an electrical interface coupled electrically to the thin-film devices and configured to electrically couple the thin-film devices to a control apparatus. The electrical interface may define a plurality of interface elements, and the apertures may be in excess over the interface elements.
Abstract translation: 一种用于生物膜电分析的生物芯片装置。 该装置可以包括限定孔阵列的衬底组件，并且包括被配置为感测密封孔的生物膜的电性质的薄膜装置。 该装置还可以包括电接口，其电耦合到薄膜器件并且被配置为将薄膜器件电耦合到控制装置。 电接口可以限定多个接口元件，并且孔可以在接口元件上过量。
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公开(公告)号：US08056556B2
公开(公告)日：2011-11-15
申请号：US10823475
申请日：2004-04-12
Applicant: Winthrop D. Childers , Douglas A. Sexton , David Tyvoll
Inventor： Winthrop D. Childers , Douglas A. Sexton , David Tyvoll
CPC classification number: A61M15/025 , A61M11/001 , A61M15/0003 , A61M15/0065 , A61M2205/70
Abstract: A medication dispenser includes a thermal drop generator ejector head. Medication is maintained in a pressurized container connected to a valve under the control of control electronics and to a compliant chamber. Fluid flows from the container to the chamber and to the ejector head. In a first mode the dispenser is operable to dispense aerosolized medication. In a second mode the ejector head is purged with fluid from the container to maintain the ejector head.
Abstract translation: 药物分配器包括热滴发生器喷射头。 在控制电子装置的控制下，将药物保持在连接到阀的加压容器中并且与顺应室相连。 流体从容器流到腔室和喷射头。 在第一模式中，分配器可操作以分配雾化药物。 在第二模式中，喷射头用来自容器的流体吹扫以保持喷射头。
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Patent Agency Ranking
公开(公告)号：US07390387B2
公开(公告)日：2008-06-24
申请号：US10808803
申请日：2004-03-25
Applicant: Winthrop D. Childers , David Tyvoll , Kirk Norton
Inventor： Winthrop D. Childers , David Tyvoll , Kirk Norton
IPC: G01N27/447 , G01N27/453
CPC classification number: B03C5/005 , B03C5/028 , B03C2201/26 , G01N2015/149
Abstract: A method of sorting cells comprises providing a fluid flow path for cell movement through a series of cell sorters in a first direction with an output of a preceding cell sorter of the series communicating with an input of a successive cell sorter of the series. Within each cell sorter, a first portion of the cells is separated from a second portion of the cells by applying a first non-uniform electric field via a first electrode array to cause movement of the first portion of the cells in a second direction across the fluid flow path, having a component generally transverse to the first direction into the output of a respective cell sorter.
Abstract translation: 一种分选细胞的方法包括提供流体流动路径，用于使细胞在第一方向上通过一系列细胞分选器移动，其中该序列的先前细胞分选器的输出与该系列的连续细胞分选器的输入通信。 在每个细胞分选器内，通过经由第一电极阵列施加第一非均匀电场，使细胞的第一部分与细胞的第二部分分离，以引起细胞的第一部分在第二方向上移动穿过 流体流动路径，具有通常横向于第一方向的分量进入相应的细胞分选器的输出。
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公开(公告)号：US07232226B2
公开(公告)日：2007-06-19
申请号：US10728642
申请日：2003-12-05
Applicant: Noah Lassar , Steven W. Steinfield , Mohammad M. Samii , Jack H. Schmidt , Matthew Giere , David Tyvoll , Winthrop D. Childers
Inventor： Noah Lassar , Steven W. Steinfield , Mohammad M. Samii , Jack H. Schmidt , Matthew Giere , David Tyvoll , Winthrop D. Childers
CPC classification number: H04N9/3114 , G02B5/24 , G02B26/004 , G09F9/37
Abstract: A light-filtering element for a display device is provided. The element includes at least one filter having a chamber with a filtering fluid, the filtering fluid selectively disposed in an optical path, and a liquid motion actuator selectively configured to move the filtering fluid substantially into and out of the optical path.
Abstract translation: 提供了一种用于显示装置的滤光元件。 所述元件包括至少一个具有过滤流体的过滤器，所述过滤流体选择性地设置在光路中，以及液体运动致动器，其选择性地配置成将所述过滤流体基本上移入和移出所述光路。
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公开(公告)号：US07741123B2
公开(公告)日：2010-06-22
申请号：US12069628
申请日：2008-02-11
Applicant: Grant Pease , Adam L Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
Inventor： Grant Pease , Adam L Ghozeil , John Stephen Dunfield , Winthrop D. Childers , David Tyvoll , Douglas A. Sexton , Paul Crivelli
CPC classification number: B01L7/525 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2200/147 , B01L2300/024 , B01L2300/0816 , B01L2300/0874 , B01L2300/1827 , B01L2300/1883 , B01L2400/0415 , Y10T436/11 , Y10T436/2575
Abstract: A microfluidic device for analysis of a sample. The microfluidic device includes a substrate portion that at least partially defines a chamber for receiving the sample. The substrate portion includes a substrate having a surface. The substrate portion also includes a plurality of thin-film layers formed on the substrate adjacent the surface. The thin-film layers form a plurality of electronic devices. Each of at least two of the electronic devices is formed by a different set of the thin-film layers.
Abstract translation: 用于分析样品的微流体装置。 微流体装置包括至少部分地限定用于接收样品的室的基底部分。 基板部分包括具有表面的基板。 衬底部分还包括在邻近表面的衬底上形成的多个薄膜层。 薄膜层形成多个电子装置。 至少两个电子设备中的每一个由不同的薄膜层组形成。
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公开(公告)号：US07390388B2
公开(公告)日：2008-06-24
申请号：US10808945
申请日：2004-03-25
Applicant: Winthrop D. Childers , David Tyvoll
Inventor： Winthrop D. Childers , David Tyvoll
IPC: G01N27/447 , G01N27/453
CPC classification number: B03C5/028 , B03C5/005 , B03C2201/26 , G01N2035/00158
Abstract: A method of sorting cells for a biodevice comprises directing a flow of cells within a fluid into a filtration structure defining an array of fluid openings and encouraging cell passage of each cell of a portion of the cells through the fluid openings based on at least one dimension of each cell via application of an electric field within the fluid openings.
Abstract translation: 一种分选用于生物装置的细胞的方法包括将流体内的细胞流引导到限定流体开口阵列的过滤结构中，并且基于至少一个维度促进细胞的一部分的每个细胞通过流体开口的细胞通过 通过在流体开口内施加电场。
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公开(公告)号：US07038867B2
公开(公告)日：2006-05-02
申请号：US11153512
申请日：2005-06-14
Applicant: Steven W. Steinfield , Mohammad M. Samii , Jack H. Schmidt , Matthew Giere , David Tyvoll , Noah Lassar , Winthrop D. Childers
Inventor： Steven W. Steinfield , Mohammad M. Samii , Jack H. Schmidt , Matthew Giere , David Tyvoll , Noah Lassar , Winthrop D. Childers
IPC: G02B5/24
CPC classification number: G02B26/004 , G02F1/133514
Abstract: A filter for a display system is provided which includes a fluid chamber having a selectively moveable filtering fluid, plural electrodes being coupled with the fluid chamber to accommodate establishment of an electric field whereby the filtering fluid may be selectively positioned in an optical path.
Abstract translation: 提供了一种用于显示系统的过滤器，其包括具有选择性可移动的过滤流体的流体室，多个电极与流体室耦合以适应电场的建立，从而过滤流体可以选择性地定位在光路中。
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