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公开(公告)号:US20050247558A1
公开(公告)日:2005-11-10
申请号:US11112867
申请日:2005-04-21
申请人: Deon Anex , Phillip Paul , David Neyer , Edwin Hlavka
发明人: Deon Anex , Phillip Paul , David Neyer , Edwin Hlavka
IPC分类号: A61M5/142 , A61M5/145 , A61M5/148 , A61M5/172 , B67D99/00 , F04B19/00 , F04B43/04 , B67D5/00
CPC分类号: A61M5/14276 , A61M5/14248 , A61M5/1483 , A61M5/1723 , A61M2005/14513 , A61M2205/52 , A61M2230/201 , F04B19/006 , F04B43/043 , Y10T137/0318 , Y10T137/0357 , Y10T137/0368 , Y10T137/0379 , Y10T137/218
摘要: A method of pumping fluid including the steps of providing an electrokinetic pump comprising a pair of double-layer capacitive electrodes having a capacitance of at least 10−2 Farads/cm2 and being connectable to a power source, a porous dielectric material disposed between the electrodes and a reservoir containing pump fluid; connecting the electrodes to a power source; and moving pump fluid out of the reservoir substantially without the occurrence of Faradaic processes in the pump. The invention also includes an electrokinetic pump system having a pair of double-layer capacitive electrodes having a capacitance of at least 10−2 Farads/cm2; a porous dielectric material disposed between the electrodes; a reservoir containing pump fluid; and a power source connected to the electrodes; the electrodes, dielectric material and power source being adapted to move the pump fluid out of the reservoir substantially without the occurrence of Faradaic processes in the pump.
摘要翻译: 一种泵送流体的方法,包括以下步骤:提供电动泵,其包括一对具有至少10欧/平方厘米/平方厘米的电容的双层电容电极和 可连接到电源,设置在电极之间的多孔介电材料和容纳泵流体的储存器; 将电极连接到电源; 并将泵流体从储存器中移出基本上不会在泵中发生法拉第过程。 本发明还包括具有一对双电容电极的电动泵系统,电容器具有至少10欧/平方英尺/平方厘米的电容; 设置在电极之间的多孔电介质材料; 包含泵液的储存器; 以及连接到所述电极的电源; 电极,电介质材料和电源适于将泵流体基本上移出储存器,而不会在泵中发生法拉第过程。
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公开(公告)号:US20070144909A1
公开(公告)日:2007-06-28
申请号:US11684500
申请日:2007-03-09
申请人: Deon Anex , Phillip Paul , David Neyer
发明人: Deon Anex , Phillip Paul , David Neyer
IPC分类号: G01N27/00
CPC分类号: F04B19/006 , F04B17/00 , F04B19/00 , F04B43/043
摘要: An electrokinetic pump achieves high and low flow rates without producing significant gaseous byproducts and without significant evolution of the pump fluid. A first feature of the pump is that the electrodes in the pump are capacitive with a capacitance of at least 10−4 Farads/cm2. A second feature of the pump is that it is configured to maximize the potential across the porous dielectric material. The pump can have either or both features.
摘要翻译: 电动泵实现高和低流速,而不产生显着的气体副产物并且没有泵流体的显着演变。 泵的第一特征是泵中的电极是电容性的,具有至少10 -4欧拉/ cm 2的电容。 泵的第二个特征是其被配置为使跨越多孔介电材料的电势最大化。 泵可以具有两个或两个特征。
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公开(公告)号:US20050161334A1
公开(公告)日:2005-07-28
申请号:US10512962
申请日:2003-04-30
申请人: Phillip Paul , David Neyer
发明人: Phillip Paul , David Neyer
IPC分类号: G01N27/447 , G01N27/453
CPC分类号: G01N27/44752
摘要: Electroosmotic flow systems containing two or more electroosmotic flow elements which meet at a junction, at least one of the electroosmotic flow elements having a substantial charge ratio. The electroosmotic flow elements have matching flux ratios. The electroosmotic flow elements may contain porous materials whose terminal portions are shaped to increase the surface area exposed to the fluid at the junction. Examples of such terminals are illustrated in the figure.
摘要翻译: 含有两个或更多个渗透流动元件的电渗流系统,其在接合处相遇,至少一个电渗流体元件具有相当大的电荷比。 电渗流量元件具有匹配的通量比。 电渗流元件可以包含多孔材料,其端部被成形以增加在接合部处暴露于流体的表面积。 这种端子的示例在附图中示出。
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公开(公告)号:US20050016853A1
公开(公告)日:2005-01-27
申请号:US10896102
申请日:2004-07-20
申请人: Phillip Paul , David Neyer
发明人: Phillip Paul , David Neyer
IPC分类号: F04B17/00 , F04B19/00 , G01N27/453 , H02K20060101
CPC分类号: F04B19/006 , F04B17/00
摘要: In accordance with the present invention, stable electroosmotic flow systems and methods for designing the same are disclosed. The invention provides electroosmotic flow systems comprising electroosmotic flow elements, including bridge elements, that have matching flux ratios, i.e., when two or more elements of an electroosmotic flow system are in fluidic and electrical communication at a junction, the flux ratio for each of the elements is selected so that the difference in flux ratios system adjacent two elements is less than a target value. The invention also provides methods for designing such systems.
摘要翻译: 根据本发明,公开了稳定的电渗流系统及其设计方法。 本发明提供了电渗流系统,其包括具有匹配通量比的电渗流元件(包括桥元件),即当电渗流系统的两个或多个元件在连接处处于流体和电连通时,每个的通量比 选择元件,使得相邻两个元件的通量比的差异小于目标值。 本发明还提供了用于设计这种系统的方法。
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公开(公告)号:US20070267292A1
公开(公告)日:2007-11-22
申请号:US11831686
申请日:2007-07-31
申请人: Phillip Paul , David Neyer
发明人: Phillip Paul , David Neyer
IPC分类号: B01D61/42
CPC分类号: F04B19/006 , F04B17/00
摘要: In accordance with the present invention, stable electroosmotic flow systems and methods for designing the same are disclosed. The invention provides electroosmotic flow systems comprising electroosmotic flow elements, including bridge elements, that have matching flux ratios, i.e., when two or more elements of an electroosmotic flow system are in fluidic and electrical communication at a junction, the flux ratio for each of the elements is selected so that the difference in flux ratios system adjacent two elements is less than a target value. The invention also provides methods for designing such systems.
摘要翻译: 根据本发明,公开了稳定的电渗流系统及其设计方法。 本发明提供了电渗流系统,其包括具有匹配通量比的电渗流元件(包括桥元件),即当电渗流系统的两个或多个元件在连接处处于流体和电连通时,每个的通量比 选择元件,使得相邻两个元件的通量比的差异小于目标值。 本发明还提供了用于设计这种系统的方法。
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公开(公告)号:US20070037293A1
公开(公告)日:2007-02-15
申请号:US10557924
申请日:2004-05-19
申请人: David Neyer
发明人: David Neyer
IPC分类号: G01N1/10
CPC分类号: G01N30/16 , G01N2030/324 , Y10T436/2575
摘要: A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably provided by variable rate working fluid supplies which drive the sample from the preparation site and through the device.
摘要翻译: 在制备部位制备液体样品,然后加工,例如 在HPLC柱中。 制备样品并以基本上小于通过装置的流速的流速将其输送到装置。 不同的流速优选由可变速率的工作流体供应提供,驱动样品从制备部位并通过该装置。
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公开(公告)号:US20050236314A1
公开(公告)日:2005-10-27
申请号:US11171854
申请日:2005-06-29
申请人: David Neyer , David Rakestraw , Jason Rehm
发明人: David Neyer , David Rakestraw , Jason Rehm
CPC分类号: G01N30/16 , G01N2030/324 , Y10T436/2575
摘要: A variable flow rate injector provides accurate, precise, and reproducible injection volumes that have low dispersion. The invention is particularly well-suited for HPLC injection volumes
摘要翻译: 可变流量注射器提供具有低色散的精确,精确和可再现的注射体积。 本发明特别适用于HPLC注射体积<500 nL,但可用于注射较大体积和不同应用。 以第一流速进行注射,并以第二流速进行分离。 为提高HPLC系统性能,第一流量小于第二流量。 注射器使用可变流量流体供应,允许在注射所需的流速和分离所需的流速之间快速切换。
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公开(公告)号:US20070183928A1
公开(公告)日:2007-08-09
申请号:US11530389
申请日:2006-09-08
CPC分类号: G01N30/32 , G01N30/34 , G01N30/36 , G01N2030/324 , G01N2030/623
摘要: A chromatography system having continuously variable sources of fluid pressure and a controller to control the flow rates of one or more carrier fluids during an HPLC separation, the controller being responsive to the rate of analyte elution from a sample.
摘要翻译: 具有连续可变的流体压力源的色谱系统和控制器,用于在HPLC分离期间控制一种或多种载体流体的流速,所述控制器响应于来自样品的分析物洗脱速率。
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公开(公告)号:US20050252772A1
公开(公告)日:2005-11-17
申请号:US10521093
申请日:2003-07-16
申请人: Philip Paul , David Neyer , Jason Rehm
发明人: Philip Paul , David Neyer , Jason Rehm
IPC分类号: G01N37/00 , B01D61/18 , B01F5/06 , B01F13/00 , B01F15/02 , B01J19/00 , B01L3/00 , B67D99/00 , F04B19/00 , F04B43/04 , F04B43/06 , F15C5/00 , F16K99/00 , G01N27/447 , G01N30/02 , G01N30/28 , G01N30/32 , G01N30/34 , G01N30/46 , G01N30/52 , G01N30/60 , G01N27/27
CPC分类号: B01F13/0076 , B01D61/18 , B01F5/0682 , B01F5/0692 , B01F15/0201 , B01F15/0232 , B01L3/5023 , B01L3/502707 , B01L3/502753 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2300/0877 , B01L2300/0887 , B01L2400/0418 , F04B19/006 , F04B43/043 , F04B43/06 , F16K99/0001 , F16K99/0025 , F16K99/0049 , G01N27/44791 , G01N30/461 , G01N30/6065 , G01N30/6095 , G01N2030/027 , G01N2030/285 , G01N2030/326 , G01N2030/347 , G01N2030/525 , G01N2030/528 , Y10T156/1046
摘要: Liquid flow devices, particularly microfluidic devices, containing solid porous materials. Flow in the devices can be pressure-driven flow and/or electroosmotic flow. The porous materials are preferably pre-shaped, for example divided from a sheet of porous material, so that they can be assembled with liquid-impermeable barrier materials around them. The devices can for example be prepared by lamination. A wide variety of devices, including mixing devices, is disclosed. A mixing device is illustrated in FIG. 23.
摘要翻译: 液体流动装置,特别是含有固体多孔材料的微流体装置。 装置中的流动可以是压力驱动的流动和/或电渗流。 多孔材料优选是预成型的,例如从多孔材料片分开,使得它们可以在其周围组装有不透液体的阻隔材料。 这些装置可以例如通过层压来制备。 公开了各种各样的装置,包括混合装置。 图1中示出了混合装置。 23。
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