Mobile monolithic polymer elements for flow control in microfluidic devices
    2.
    发明申请
    Mobile monolithic polymer elements for flow control in microfluidic devices 审中-公开
    用于微流体装置中流动控制的移动单片聚合物元件

    公开(公告)号:US20050004250A1

    公开(公告)日:2005-01-06

    申请号:US10891528

    申请日:2004-07-14

    摘要: A cast-in-place and lithographically shaped mobile, monolithic polymer element for fluid flow control in microfluidic devices and method of manufacture. Microfluid flow control devices, or microvalves that provide for control of fluid or ionic current flow can be made incorporating a cast-in-place, mobile monolithic polymer element, disposed within a microchannel, and driven by either fluid or gas pressure against a retaining or sealing surface. The polymer elements are made by the application of lithographic methods to monomer mixtures formulated in such a way that the polymer will not bond to microchannel walls. The polymer elements can seal against pressures greater than 5000 psi, and have a response time on the order of milliseconds. By the use of energetic radiation it is possible to depolymerize selected regions of the polymer element to form shapes that cannot be produced by conventional lithographic patterning and would be impossible to machine.

    摘要翻译: 用于微流体装置中流体流动控制的现浇和光刻形移动式整体式聚合物元件及其制造方法。 提供控制流体或离子电流的微流量控制装置或微型阀可以包括设置在微通道内的现浇可移动整体式聚合物元件,并通过流体或气体压力驱动抵靠保持或 密封面。 通过将光刻方法应用于以聚合物不会结合到微通道壁的方式配制的单体混合物来制备聚合物元件。 聚合物元件可以密封大于5000psi的压力,并且具有大约毫秒级的响应时间。 通过使用高能辐射,可以解聚聚合物元件的选定区域以形成不能通过常规平版印刷图案产生的形状,并且不可能加工。

    Variable flow rate injector
    4.
    发明申请
    Variable flow rate injector 审中-公开
    可变流量注射器

    公开(公告)号:US20050236314A1

    公开(公告)日:2005-10-27

    申请号:US11171854

    申请日:2005-06-29

    IPC分类号: G01N30/16 G01N30/32 B01D15/08

    摘要: A variable flow rate injector provides accurate, precise, and reproducible injection volumes that have low dispersion. The invention is particularly well-suited for HPLC injection volumes

    摘要翻译: 可变流量注射器提供具有低色散的精确,精确和可再现的注射体积。 本发明特别适用于HPLC注射体积<500 nL,但可用于注射较大体积和不同应用。 以第一流速进行注射,并以第二流速进行分离。 为提高HPLC系统性能,第一流量小于第二流量。 注射器使用可变流量流体供应,允许在注射所需的流速和分离所需的流速之间快速切换。

    Particle-based check valve
    8.
    发明授权
    Particle-based check valve 失效
    基于颗粒的止回阀

    公开(公告)号:US06802331B2

    公开(公告)日:2004-10-12

    申请号:US10112718

    申请日:2002-03-28

    IPC分类号: F16K1500

    摘要: A check valve for a fluidic system includes a fluidic conduit having an inlet with a first particle barrier, an outlet with a second particle barrier and a fluid chamber between the inlet and the outlet; and at least one particle disposed in the fluid chamber, the particle or particles aggregating at the first particle barrier to form a first hydrodynamic resistance when a first fluid pressure at the inlet is less than a second fluid pressure at the outlet, the particle or particles aggregating at the second particle barrier to form a second hydrodynamic resistance when the first fluid pressure is greater than the second fluid pressure.

    摘要翻译: 用于流体系统的止回阀包括流体导管,其具有具有第一颗粒屏障的入口,具有第二颗粒屏障的出口和在入口与出口之间的流体室; 以及设置在流体室中的至少一个颗粒,当入口处的第一流体压力小于出口处的第二流体压力时,颗粒或颗粒聚集在第一颗粒屏障处以形成第一流体动力学阻力,颗粒或颗粒 当第一流体压力大于第二流体压力时,在第二颗粒屏障处聚集以形成第二流体动力学阻力。