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    Disinfection of dead-ended lines in medical instruments
    3.
    发明授权
    Disinfection of dead-ended lines in medical instruments 有权
    消毒医疗器械中的死线

    公开(公告)号：US6153102A

    公开(公告)日：2000-11-28

    申请号：US236764

    申请日：1999-01-25

    申请人： Rodney S. Kenley ,  Derek Wiebenson

    发明人： Rodney S. Kenley ,  Derek Wiebenson

    IPC分类号： A61L2/04 ,  A61L2/18 ,  A61M1/16 ,  A61M1/34 ,  B01D61/02 ,  B01D61/04 ,  B01D61/12 ,  B01D65/02 ,  B01D65/10 ,  C02F1/44 ,  A61L2/00 ,  A61L2/16

    CPC分类号： A61L2/04 ,  A61L2/18 ,  A61M1/165 ,  A61M1/1668 ,  A61M1/1686 ,  A61M1/3431 ,  A61M1/3434 ,  B01D61/02 ,  B01D61/025 ,  B01D61/027 ,  B01D61/04 ,  B01D61/12 ,  B01D65/022 ,  B01D65/027 ,  B01D65/10 ,  C02F1/441 ,  A61M2205/505 ,  B01D2311/04 ,  B01D2321/08

    摘要： A method of disinfection of a dead-ended fluid line in a medical instrument such as a dialysis machine is described. The method comprises introducing a heated fluid into the fluid line, allowing the fluid to remain in the line for an experimentally determined optimal dwell period, removing the fluid from the fluid line, and then repeating the cycle for a time period sufficient to achieve a disinfection of the fluid line. The optimum dwell period and frequency for exchanging the heated fluid is determined so that the heated fluid is left resident in the line to exert a cidal effect but not so long that the it cools to the point of being ineffective, nor changed so frequently that that the time spent with no hot water resident in the line begins to detract (e.g., unduly prolong) the disinfection process. A representative cycle is introducing water at a temperature of about 85 degrees C, allowing it to reside in the fluid line for about 10 seconds, withdrawing the water, and then reintroducing water at 85 degrees C. The process continues for 1-2 hours. Variation from the representative cycle will be expected based on parameters such as the degree to which disinfection is to be achieved, the length and diameter of the fluid line, the temperature of the fluid, the ambient temperature, the presence of elements in the fluid line that contribute to heat loss, the material used for fluid line tubing, and whether the fluid comprises water or a disinfection solution such as a dilute citric acid solution. The optimum dwell period and frequency of the cycles can be determined experimentally from the teachings described herein.

    摘要翻译： 描述了诸如透析机之类的医疗器械中的死端流体管线的消毒方法。 该方法包括将加热的流体引入流体管线中，允许流体保持在管线中以实现实际确定的最佳停留时间，从流体管线去除流体，然后重复该循环足以实现消毒的时间 的流体线。 确定用于更换加热流体的最佳停留时间和频率，使得加热的流体留在管线中以产生杀戮效果，但不会太长，使得其冷却至无效点，也不频繁地改变 在这条线上居住的没有热水的时间开始损害（例如，不当地延长）消毒过程。 代表性的循环是在约85℃的温度下引入水，使其在流体管线中停留约10秒，取出水，然后在85℃下重新引入水。该过程持续1-2小时。 基于代表性循环的变化将基于诸如要实现消毒的程度，流体管线的长度和直径，流体的温度，环境温度，流体管线中的元素的存在等参数 有助于热损失，用于流体管线的材料以及流体是否包含水或诸如稀柠檬酸溶液的消毒溶液。 循环的最佳停留时间和频率可以从本文所述的教导实验确定。