Whitening cosmetic composition
    1.
    发明申请
    Whitening cosmetic composition 审中-公开
    美白化妆品美白

    公开(公告)号:US20050208002A1

    公开(公告)日:2005-09-22

    申请号:US10506335

    申请日:2003-03-06

    摘要: A preparation for external use on skin which comprises an active ingredient exhibiting superior effects of preventing pigmentation or eliminating pigments formed in the skin, and has a high level of safety, and in particular, a cosmetic composition exhibiting superior so-called whitening effects, are provided. The whitening cosmetic composition comprises a tocopherol alkylglycine ester and/or a salt thereof.

    摘要翻译: 皮肤外用的制剂,其特征在于,具有表现出优异的防止色素沉着的作用的活性成分或消除皮肤中形成的颜料,并且具有高水平的安全性,特别是具有优异的所谓的美白效果的化妆品组合物。 提供。 美白化妆品组合物包含生育酚烷基甘氨酸酯和/或其盐。

    Agent for Skin External Use Containing Tocopherol Derivative, Ascorbic Acid Derivative and Surface Active Agent Having Lipopeptide Structure
    4.
    发明申请
    Agent for Skin External Use Containing Tocopherol Derivative, Ascorbic Acid Derivative and Surface Active Agent Having Lipopeptide Structure 审中-公开
    含有生育酚衍生物,抗坏血酸衍生物和具有脂肽结构的表面活性剂的皮肤外用剂

    公开(公告)号:US20070232687A1

    公开(公告)日:2007-10-04

    申请号:US11587809

    申请日:2005-04-19

    IPC分类号: A61K31/355

    摘要: The agent for skin external use of the present invention contains (A) tocopherol glycine esters, (B) ascorbic acid-2-phosphoric acid esters and a specific amount of (C) an anionic surface active agent having a lipopeptide structure. According to the agent for skin external use (including a cosmetic) of the present invention, it is possible to enhance stability of the tocopherol glycine esters in spite that the tocopherol glycine esters and the ascorbic acids are contained simultaneously, so that occurrence of coloring (including turbidity) and/or precipitation with time can be prevented. Therefore, efficacy and effects of the agent or the cosmetic can be well exerted over a long period of time.

    摘要翻译: 本发明的皮肤外用剂包含(A)生育酚甘氨酸酯,(B)抗坏血酸-2-磷酸酯和特定量的(C)具有脂肽结构的阴离子表面活性剂。 根据本发明的皮肤外用剂(包括化妆品),尽管生育酚甘氨酸酯和抗坏血酸同时含有,但是可以提高生育酚甘氨酸酯的稳定性,从而发生着色( 包括浊度)和/或随时间的沉淀。 因此,药剂或化妆品的功效和效果可以很好地长期施行。

    Skin whitening external preparation
    5.
    发明申请
    Skin whitening external preparation 审中-公开
    皮肤美白外用配方

    公开(公告)号:US20050220733A1

    公开(公告)日:2005-10-06

    申请号:US10513371

    申请日:2003-05-07

    摘要: The invention relates to skin whitening external preparations which contain tocopherol phosphate and/or a salt thereof as an active ingredient capable of prevention and/or removal of skin pigmentation, cosmetics including the skin whitening external preparation and cosmetic cares using the cosmetic. The skin whitening external preparations have excellent skin whitening effects and are readily producible so that they can find wide use for the purpose of skin whitening.

    摘要翻译: 本发明涉及含有生育酚磷酸酯和/或其盐作为能够预防和/或去除皮肤色素沉积的化妆品的皮肤美白外用制剂,包括皮肤美白外用剂的化妆品和使用该化妆品的化妆品护理。 皮肤美白外用制剂具有优异的皮肤美白效果,并且易于生产,使得它们可以广泛用于皮肤美白的目的。

    Multilayer wiring substrate
    7.
    发明申请
    Multilayer wiring substrate 有权
    多层布线基板

    公开(公告)号:US20080227312A1

    公开(公告)日:2008-09-18

    申请号:US12076014

    申请日:2008-03-12

    IPC分类号: H01R12/06

    摘要: A first wiring pattern formed on a first layer of a multilayer wiring substrate, a second wiring pattern formed on a layer different from the first layer on which the first wiring pattern is formed, a penetration hole penetrating the front surface and the back surface of the substrate, and a penetration hole penetrating a front surface and a back surface of the substrate; and a fitting connector having a conductor part on a side surface inscribed in the penetration hole and fitting into the penetration hole are provided. The first wiring pattern and the second wiring pattern are exposed from the internal surface of the penetration hole, and the fitting connector connects a first end part of the conductor part and a second end part with an exposed part of the first wiring pattern and an exposed part of the second wiring pattern, respectively.

    摘要翻译: 形成在多层布线基板的第一层上的第一布线图案,形成在与形成有第一布线图案的第一层不同的层上的第二布线图案,穿透第一布线图案的前表面和后表面的穿透孔 基板和穿透基板的前表面和后表面的穿透孔; 以及配合连接器,其具有位于贯通孔内侧的嵌合于贯通孔的侧面的导体部。 第一布线图案和第二布线图案从穿孔的内表面露出,并且嵌合连接器将导体部的第一端部和第二端部与第一布线图案的露出部分连接, 分别是第二布线图案的一部分。

    Composition for enhancing immunological effects
    8.
    发明授权
    Composition for enhancing immunological effects 失效
    用于增强免疫学效果的组合物

    公开(公告)号:US06635253B2

    公开(公告)日:2003-10-21

    申请号:US09794161

    申请日:2001-02-28

    IPC分类号: A61K3938

    摘要: An object of the present invention is to provide a composition for enhancing the immunological effects of a vaccine for viruses, bacteria and/or infectious disease pathogens, containing a stable activity-type provitamin; a method for enhancing the immunological effects of a vaccine for viruses, bacteria and/or infectious disease pathogens by administering the composition; and a method of employing the composition. A composition for enhancing the immunological effects of a vaccine for viruses, bacteria and/or infectious disease pathogens, contains L-ascorbic acid-2-phosphate and/or &agr;-tocopheryl phosphate as a stable activity antioxidant provitamin.

    摘要翻译: 本发明的目的是提供一种用于增强含有稳定的活性型前病毒的病毒,细菌和/或感染性疾病病原体的疫苗的免疫效果的组合物; 通过施用组合物来增强疫苗对病毒,细菌和/或感染性疾病病原体的免疫效果的方法; 和采用该组合物的方法。 用于增强疫苗对病毒,细菌和/或感染性疾病病原体的免疫效果的组合物含有L-抗坏血酸-2-磷酸和/或α-生育酚磷酸酯作为稳定活性的抗氧化剂前维生素。

    Process for preparing 4,4'-dihydroxydiphenyl sulfone having high purity
    9.
    发明授权
    Process for preparing 4,4'-dihydroxydiphenyl sulfone having high purity 失效
    制备高纯度的4,4'-二羟基二苯砜的方法

    公开(公告)号:US4820831A

    公开(公告)日:1989-04-11

    申请号:US10095

    申请日:1986-12-12

    CPC分类号: C07C317/00

    摘要: The process of the present invention is a process for preparing 4,4'-dihydroxydiphenyl sulfone by subjecting phenol, and a sulfonating agent or phenolsulfonic acid to a dehydration reaction in the presence of a solvent, subsequently maintaining the reaction system at a temperature of between 100.degree. to 200.degree. C. and removing the solvent from the reaction system to cause the dehydration reaction to further proceed while allowing 4,4'-dihydroxydiphenyl sulfone to separate out and to subject dissolved 2,4'-dihydroxydiphenyl sulfone formed as a by-product to an isomerization reaction for converting the by-product to 4,4'-dihydroxydiphenyl sulfone, and eventually removing the solvent and the unreacted phenol from the system substantially entirely to complete the isomerization reaction, the process being characterized in that an aromatic sulfonic acid represented by the formula ##STR1## wherein X is a halogen atom, n is 0, 1 or 2, and m is 1 of 2 is caused to be present in the reaction system. 4,4'-Dihydroxydiphenyl sulfone can be produced by the process with a high purity and in a high yield.

    摘要翻译: PCT No.PCT / JP86 / 00194 Sec。 371日期:1986年12月12日 102(e)日期1986年12月12日PCT提交1986年4月17日PCT公布。 公开号WO86 / 06370 日本1986年11月6日。本发明的方法是通过在溶剂存在下使苯酚和磺化剂或苯酚磺酸进行脱水反应来制备4,4'-二羟基二苯基砜的方法, 反应体系在100〜200℃的温度下,从反应体系中除去溶剂,使脱水反应进一步进行,同时使4,4'-二羟基二苯砜分离出来并使溶解的2,4' - 二羟基二苯砜作为副产物形成异构化反应,用于将副产物转化为4,4'-二羟基二苯基砜,并最终从体系中除去溶剂和未反应的苯酚,完全完全异构化反应,该方法 其特征在于,由式“IMAGE”表示的芳族磺酸,其中X为卤素原子,n为0,1或2,m为2的m为芳族磺酸存在于 反应体系。 4,4'-二羟基二苯砜可以通过高纯度和高收率的方法生产。

    Process for preparing halo-substituted diarylsulfones
    10.
    发明授权
    Process for preparing halo-substituted diarylsulfones 失效
    卤代二芳基砜的制备方法

    公开(公告)号:US4558161A

    公开(公告)日:1985-12-10

    申请号:US588865

    申请日:1984-01-25

    CPC分类号: C07C317/00

    摘要: A process for preparing diarylsulfone, the process comprising reacting chlorosulfonic acid with a mixture of (i) aromatic hydrocarbon represented by the formula ##STR1## wherein one of X and Y is a halogen atom and the other is a halogen atom or a hydrogen atom and (ii) aromatic sulfonic acid represented by the formula ##STR2## wherein X and Y are as defined above.

    摘要翻译: PCT No.PCT / JP83 / 00155 Sec。 371日期1984年1月25日 102(e)日期1984年1月25日PCT提交1983年5月20日PCT公布。 公开号WO83 / 04251 日本公报1983年12月8日。一种制备二芳基砜的方法,该方法包括使氯磺酸与(ⅰ)式(ⅰ)表示的芳族烃的混合物反应,其中X和Y之一是卤素原子,另一个是 卤素原子或氢原子,和(ii)由式“IMAGE”表示的芳族磺酸,其中X和Y如上所定义。