公开(公告)号：US20070105930A1

公开(公告)日：2007-05-10

申请号：US10580183

申请日：2004-12-15

申请人： Emma Parmee ,  Ronald Kim ,  Elizabeth Rouse ,  Darby Schmidt ,  Christopher Sinz ,  Jiang Chang

发明人： Emma Parmee ,  Ronald Kim ,  Elizabeth Rouse ,  Darby Schmidt ,  Christopher Sinz ,  Jiang Chang

IPC分类号： A61K31/4184 ,  C07D235/28

CPC分类号： C07D403/12 ,  C07D235/30 ,  C07D409/12

摘要： The present invention relates to cyclic guanidines, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.

摘要翻译： 本发明涉及环状胍，含有这些化合物的组合物和处理方法。 该化合物是胰高血糖素受体拮抗剂，因此可用于治疗，预防或延缓2型糖尿病的发作。

公开(公告)号：US20080085926A1

公开(公告)日：2008-04-10

申请号：US11906374

申请日：2007-10-02

申请人： John Stelmach ,  Emma Parmee ,  James Tata ,  Keith Rosauer ,  Ronald Kim ,  Amy Bittner ,  Jiang Chang ,  Christopher Sinz

发明人： John Stelmach ,  Emma Parmee ,  James Tata ,  Keith Rosauer ,  Ronald Kim ,  Amy Bittner ,  Jiang Chang ,  Christopher Sinz

IPC分类号： A61K31/404 ,  A61P3/04 ,  A61P3/10 ,  A61P9/10 ,  C07D209/04

CPC分类号： C07D209/18

摘要： Glucagon receptor antagonist compounds are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.

摘要翻译： 公开了胰高血糖素受体拮抗剂化合物。 该化合物可用于治疗2型糖尿病及相关病症。 还包括药物组合物和治疗方法。

公开(公告)号：US20070093544A1

公开(公告)日：2007-04-26

申请号：US10556230

申请日：2004-05-05

申请人： Emma Parmee ,  Ronald Kim ,  Rui Liang ,  Jiang Chang ,  Elizabeth Rouse ,  Kevin Chapman

发明人： Emma Parmee ,  Ronald Kim ,  Rui Liang ,  Jiang Chang ,  Elizabeth Rouse ,  Kevin Chapman

IPC分类号： A61K31/4184 ,  C07D403/02 ,  C07D235/28

CPC分类号： C07D235/30 ,  C07D403/12 ,  H04N5/4401 ,  H04N7/0887 ,  H04N7/163 ,  H04N21/4532 ,  H04N21/4542 ,  H04N21/84

摘要： The present invention relates to substituted benzimidazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.

摘要翻译： 本发明涉及取代的苯并咪唑，含有这些化合物的组合物和治疗方法该化合物是胰高血糖素受体拮抗剂，因此可用于治疗，预防或延缓2型糖尿病的发作。

公开(公告)号：US08901087B2

公开(公告)日：2014-12-02

申请号：US13883811

申请日：2011-11-08

申请人： Jiang Chang ,  Kun Liu ,  Ernest J. McEachern ,  Changwei Mu ,  Harold G. Selnick ,  Feng Shi ,  David J. Vocadlo ,  Yaode Wang ,  Zhongyong Wei ,  Yuanxi Zhou ,  Yongbao Zhu

发明人： Jiang Chang ,  Kun Liu ,  Ernest J. McEachern ,  Changwei Mu ,  Harold G. Selnick ,  Feng Shi ,  David J. Vocadlo ,  Yaode Wang ,  Zhongyong Wei ,  Yuanxi Zhou ,  Yongbao Zhu

IPC分类号： C08B37/00 ,  C07D487/02 ,  A61K31/70 ,  A61K31/425 ,  C07D513/04

CPC分类号： C07D513/04

摘要： The invention is directed to compounds for selectively inhibiting glycosidases, uses of the compounds and pharmaceutical compositions including the compounds, and methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, and/or accumulation or deficiency of O-GlcNAc.

摘要翻译： 本发明涉及用于选择性抑制糖苷酶的化合物，化合物的用途和包含该化合物的药物组合物，以及治疗与O-GlcNAC的缺乏或过度表达有关的疾病和障碍和/或O-GlcNAc的积累或缺陷的方法。

公开(公告)号：US20130072492A1

公开(公告)日：2013-03-21

申请号：US13699046

申请日：2011-05-24

申请人： Subharekha Raghavan ,  John E. Stelmach ,  Cameron J. Smith ,  Hong Li ,  Alan Whitehead ,  Sherman T. Waddell ,  Yi-Heng Chen ,  Shouwu Miao ,  Olga A. Ornoski ,  Joie Garfunkle ,  Xibin Liao ,  Jiang Chang ,  Xiaoqing Han ,  Jian Guo ,  Jonathan A. Groeper ,  Linda L. Brockunier ,  Keith Rosauer ,  Emma R. Parmee

发明人： Subharekha Raghavan ,  John E. Stelmach ,  Cameron J. Smith ,  Hong Li ,  Alan Whitehead ,  Sherman T. Waddell ,  Yi-Heng Chen ,  Shouwu Miao ,  Olga A. Ornoski ,  Joie Garfunkle ,  Xibin Liao ,  Jiang Chang ,  Xiaoqing Han ,  Jian Guo ,  Jonathan A. Groeper ,  Linda L. Brockunier ,  Keith Rosauer ,  Emma R. Parmee

IPC分类号： C07D487/04 ,  C07D495/04 ,  A61K31/5025 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  A61P9/04 ,  A61P7/02 ,  A61P15/00 ,  A61P11/06 ,  A61P13/12 ,  A61P3/10 ,  A61P1/16 ,  A61P9/08 ,  A61P3/00 ,  A61P3/06 ,  A61P7/10 ,  A61K31/519

CPC分类号： C07D487/04 ,  A61K31/519 ,  C07D519/00

摘要： A compound of Formula (I): or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula (I) or a pharmaceutically acceptable salt thereof.

摘要翻译： 式（I）的化合物或其药学上可接受的盐能够调节人体的环鸟苷酸（cGMP）的产生，并且通常适用于治疗和预防与扰动的cGMP平衡有关的疾病。 本发明还涉及用于制备式I化合物或其药学上可接受的盐的方法，用于治疗和预防上述疾病和用于制备用于该目的的药物以及包含式（III）化合物的药物制剂 I）或其药学上可接受的盐。

公开(公告)号：US20070177500A1

公开(公告)日：2007-08-02

申请号：US11456599

申请日：2006-07-11

申请人： Jiang Chang ,  Jun Qiang Liu ,  Wen Tao Zhang

发明人： Jiang Chang ,  Jun Qiang Liu ,  Wen Tao Zhang

IPC分类号： H04L12/26 ,  H04J1/16 ,  H04Q7/00

CPC分类号： H04W72/1226

摘要： The present invention provides a method of radio resource allocation. The method comprises associating a plurality of mobile units with a corresponding plurality of scheduling states based on at least one radio resource parameter and at least one rule, associating each mobile unit with one allocation state based on the plurality of scheduling states associated with the mobile units, and allocating radio resource to at least one mobile units based on the allocation states.

摘要翻译： 本发明提供一种无线资源分配方法。 所述方法包括：基于至少一个无线电资源参数和至少一个规则，将多个移动单元与相应的多个调度状态相关联，所述至少一个规则基于与所述移动单元相关联的所述多个调度状态将每个移动单元与一个分配状态相关联 并且基于分配状态将无线电资源分配给至少一个移动单元。

公开(公告)号：US11379173B2

公开(公告)日：2022-07-05

申请号：US16950021

申请日：2020-11-17

申请人： Jiang Chang

发明人： Jiang Chang

IPC分类号： G06F3/14 ,  H04N5/33 ,  G06F3/01 ,  H04N13/133 ,  H04N13/275 ,  H04N13/282 ,  H04N13/327 ,  G09G5/02 ,  H04N13/324 ,  G06F3/147

摘要： A method and system for a displaying content that makes LED real-time 3D displays possible. The 3D image formation includes multi-screen display color correction and multi-camera infrared positioning technology. The present invention presents the display effects of a simulation environment in a better way through switching and moving and ensures that while in movement, the display effects of LED screens taken by video cameras from different angles can be maintained the same, so as to create a vivid simulation environment for television programming and film shooting. The system for maintaining accuracy in a 3D image formation includes a multi-screen display color correction system, a multi-screen display color correction system comprising a large-size screen server, a video camera and a large-size display screen wherein the large-size screen color correction server includes an image input module, a position data module, a comprehensive color correction server and an image output module.

公开(公告)号：US10976980B2

公开(公告)日：2021-04-13

申请号：US16669833

申请日：2019-10-31

申请人： Jiang Chang

发明人： Jiang Chang

IPC分类号： G06F3/14 ,  H04N5/33 ,  G06F3/01 ,  H04N13/133 ,  H04N13/275 ,  H04N13/282 ,  H04N13/327 ,  G09G5/02 ,  H04N13/324 ,  G06F3/147

摘要： A method and system for a displaying content that makes LED real-time 3D displays possible. The 3D image formation includes multi-screen display color correction and multi-camera infrared positioning technology. The present invention presents the display effects of a simulation environment in a better way through switching and moving and ensures that while in movement, the display effects of LED screens taken by video cameras from different angles can be maintained the same, so as to create a vivid simulation environment for television programming and film shooting. The system for maintaining accuracy in a 3D image formation includes a multi-screen display color correction system, a multi-screen display color correction system comprising a large-size screen server, a video camera and a large-size display screen wherein the large-size screen color correction server includes an image input module, a position data module, a comprehensive color correction server and an image output module.

公开(公告)号：US20100192632A1

公开(公告)日：2010-08-05

申请号：US12798660

申请日：2010-04-06

申请人： Jiang Chang ,  Weiming Gu ,  Jipin Zhong

发明人： Jiang Chang ,  Weiming Gu ,  Jipin Zhong

IPC分类号： C03B19/09

CPC分类号： A61F2/28 ,  A61F2/4644 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30011 ,  A61F2002/30032 ,  A61F2002/30062 ,  A61F2002/30224 ,  A61F2002/30957 ,  A61F2002/30968 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61F2250/0023 ,  A61F2250/003 ,  A61F2310/00329 ,  A61L27/10 ,  A61L27/56 ,  A61L27/58 ,  C03B19/06 ,  C03B19/08 ,  C03C3/062 ,  C03C3/097 ,  C03C3/112 ,  C03C4/0007 ,  C03C4/0014 ,  C03C11/00 ,  C03C12/00 ,  C03C14/00 ,  C03C14/008

摘要： A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 24-45% CaO, 34-50% SiO2, 0-25% Na2O, 5-17% P2O5, 0-5% MgO and 0-1% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.

摘要翻译： 一种制造可再吸收的大孔生物活性玻璃支架的方法，其包括以质量计约24-45％的CaO，34-50％的SiO 2，0-25％的Na 2 O，5-17％的P 2 O 5，0-5％的MgO和0-1％的CaF 2 百分比，通过与成孔剂混合和特定的热处理产生。

公开(公告)号：US07697938B2

公开(公告)日：2010-04-13

申请号：US11456599

申请日：2006-07-11

申请人： Jiang Chang ,  Jun Qiang Liu ,  Wen Tao Zhang

发明人： Jiang Chang ,  Jun Qiang Liu ,  Wen Tao Zhang

IPC分类号： H04W72/00

CPC分类号： H04W72/1226

摘要： The present invention provides a method of radio resource allocation. The method comprises associating a plurality of mobile units with a corresponding plurality of scheduling states based on at least one radio resource parameter and at least one rule, associating each mobile unit with one allocation state based on the plurality of scheduling states associated with the mobile units, and allocating radio resource to at least one mobile units based on the allocation states.

摘要翻译： 本发明提供一种无线资源分配方法。 所述方法包括：基于至少一个无线电资源参数和至少一个规则，将多个移动单元与相应的多个调度状态相关联，所述至少一个规则基于与所述移动单元相关联的所述多个调度状态将每个移动单元与一个分配状态相关联 并且基于分配状态将无线电资源分配给至少一个移动单元。