公开(公告)号：US08814135B2

公开(公告)日：2014-08-26

申请号：US12868941

申请日：2010-08-26

申请人： Felix Ams ,  Martin Vogt

发明人： Felix Ams ,  Martin Vogt

IPC分类号： F16K31/02 ,  F16K25/00 ,  F16F9/30 ,  H01F7/08 ,  F16K31/06

CPC分类号： F16K31/0655 ,  F16K31/0686

摘要： A device for controlling the flow of a liquid or gaseous medium, has at least one flow opening for the medium, and a movable valve element for controlling the flow opening. At least one damping body, which is preferably viscoelastic and acts on the valve element, is provided for obtaining a large dynamic range of the device in order to control flow in a fine, precise, and oscillation-free manner across a broad range of flow volume.

摘要翻译： 用于控制液体或气体介质的流动的装置具有用于介质的至少一个流动开口和用于控制流动开口的可移动阀元件。 提供至少一个阻尼体，其优选地是粘弹性的并且作用在阀元件上，用于获得该装置的大的动态范围，以便在很宽的流动范围内以精细，精确和无振动的方式控制流动 卷。

公开(公告)号：US20110315907A1

公开(公告)日：2011-12-29

申请号：US12868941

申请日：2010-08-26

申请人： Felix Ams ,  Martin Vogt

发明人： Felix Ams ,  Martin Vogt

IPC分类号： F16K31/02

CPC分类号： F16K31/0655 ,  F16K31/0686

摘要： A device for controlling the flow of a liquid or gaseous medium, has at least one flow opening for the medium, and a movable valve element for controlling the flow opening. At least one damping body, which is preferably viscoelastic and acts on the valve element, is provided for obtaining a large dynamic range of the device in order to control flow in a fine, precise, and oscillation-free manner across a broad range of flow volume.

摘要翻译： 用于控制液体或气体介质的流动的装置具有用于介质的至少一个流动开口和用于控制流动开口的可移动阀元件。 提供至少一个阻尼体，其优选地是粘弹性的并且作用在阀元件上，用于获得该装置的大的动态范围，以便在很宽的流动范围内以精细，精确和无振动的方式控制流动 卷。

公开(公告)号：US20090214453A1

公开(公告)日：2009-08-27

申请号：US12086648

申请日：2006-12-11

申请人： Stefan Müller ,  Jurg Haase ,  Thomas Ehlis ,  Gilbert Kreyer ,  Jochen Giesinger ,  Martin Vogt

发明人： Stefan Müller ,  Jurg Haase ,  Thomas Ehlis ,  Gilbert Kreyer ,  Jochen Giesinger ,  Martin Vogt

IPC分类号： A61Q17/04 ,  C07D241/04

CPC分类号： C07D295/192 ,  A61K8/411 ,  A61K8/42 ,  A61K8/49 ,  A61K8/494 ,  A61K2800/43 ,  A61Q17/04

摘要： Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic compound which has a UV-Vis spectrum with a maximum from 380 to 420 nm; and (b) an anionic dispersing agent for protecting the human skin from browning and skin aging.

摘要翻译： 公开了包含（a）微波化的微溶有机化合物的水分散体的使用，其具有最大值为380至420nm的UV-Vis光谱; 和（b）用于保护人体皮肤免于褐变和皮肤老化的阴离子分散剂。

公开(公告)号：US20080314544A1

公开(公告)日：2008-12-25

申请号：US11658691

申请日：2005-07-25

申请人： Wilhelm Gansberger ,  Martin Vogt ,  Georg Bacovsky

发明人： Wilhelm Gansberger ,  Martin Vogt ,  Georg Bacovsky

IPC分类号： D21F3/08

CPC分类号： D21H23/28 ,  D21F3/02 ,  D21F3/045 ,  D21F5/04 ,  D21G9/009 ,  D21H17/28 ,  D21H23/56 ,  D21H23/58 ,  D21H23/72

摘要： Disclosed is a machine for producing a paper web, cardboard web, or other fiber web (1), comprising a press section (2) which is provided with at least one press nip (5) formed by two squeeze rollers (3, 4) and in which a device (6, 7) for applying a medium, particularly starch, is disposed. The fiber web (1) can be guided through the press nip (5) along with a band (8). The inventive machine is characterized in that the device (6, 7) rests against at least one of the squeeze rollers (3, 4) for indirectly applying the medium to the fiber web (1).

摘要翻译： 公开了一种用于生产纸幅，纸板腹板或其它纤维网（1）的机器，其包括压榨部分（2），所述压榨部分设置有由两个挤压辊（3,4）形成的至少一个挤压压区（5） 并且其中设置用于施加介质，特别是淀粉的装置（6,7）。 纤维网（1）可以与带（8）一起被引导通过压榨压区（5）。 本发明的机器的特征在于，装置（6,7）靠在挤压辊（3,4）中的至少一个上，以间接地将介质施加到纤维网（1）上。

公开(公告)号：US07207801B2

公开(公告)日：2007-04-24

申请号：US10472494

申请日：2002-04-29

申请人： Martin Vogt ,  Hans Schurch

发明人： Martin Vogt ,  Hans Schurch

IPC分类号： A61C8/00

CPC分类号： A61C8/0001 ,  A61C8/0087

摘要： An assembly for handling a bone implant includes a transfer cap which can be snapped onto the implant, and an adapter which engages with the implant. The head of the implant has a polygonal socket, an outer implant shoulder, and a shoulder edge located beneath the shoulder, while the transfer cap has an elastic lip that snaps over the shoulder edge, and the adapter has a polygonal drive projection adapted to engage within the polygonal socket. The adapter also has a plug-type extension for attaching a screw-in instrument. When the transfer cap is snapped onto the implant and the adapter is inserted, the polygonal projection engages with the polygonal socket on the implant, while the plug-type extension of the adapter that projects through the transfer cap is located on the outside. The transfer cap and the adapter plugged therein are detachably connected to one another.

摘要翻译： 用于处理骨植入物的组件包括可以咬合到植入物上的转移帽和与植入物接合的适配器。 植入物的头部具有多边形插座，外部植入物肩部和位于肩部下方的肩部边缘，而转移帽具有紧贴在肩部边缘上的弹性唇缘，并且适配器具有多边形驱动突出部， 在多边形插座内。 适配器还具有用于连接螺旋式仪器的插头式延伸件。 当转印帽咬合到植入物上并且适配器被插入时，多边形突起与植入物上的多边形插座接合，而通过转印盖突出的适配器的插头型延伸部位于外部。 插入其中的转印帽和适配器彼此可拆卸地连接。

公开(公告)号：US09176079B2

公开(公告)日：2015-11-03

申请号：US14111660

申请日：2012-03-01

申请人： Werner Runft ,  Iulian Maga ,  Jens Schlipf ,  Martin Vogt

发明人： Werner Runft ,  Iulian Maga ,  Jens Schlipf ,  Martin Vogt

IPC分类号： B07C5/346 ,  G01N23/18 ,  G01N33/15 ,  G01N23/08 ,  G01N21/95 ,  A61J3/07

CPC分类号： G01N23/18 ,  A61J3/074 ,  B07C5/346 ,  G01N21/9508 ,  G01N23/06 ,  G01N33/15

摘要： The invention relates to a device (10; 10a) for controlling pharmaceutical products (1) in particular, hard gelatin capsules, by means of a radiation source (11) preferably designed as an X-ray source, comprising a storage device (13) which receives the products (1) in an uncontrolled manner, and from which the products (1) are transferred to a transport element (15) in which the products (1) are arranged such that they form at least one row. The products (1) are transported in a clocked manner in the radiation area (25) of the radiation source (11) which exposes the products (1) to radiation, preferably perpendicular to the longitudinal direction thereof. A first stopping device (20) for separating the products (1) in the row is arranged upstream of the radiation source (11) in the direction of transportation (18) of the products (1), and at least one sensor element (28, 28a) coupled to an evaluation device (30) captures the radiation which passed through the products (1). According to the invention, at least two products (1) are separated from the row by means of the first stopping device (20) and are simultaneously positioned in the radiation area (25) and the image of the product (1) is captured by means of the at least one sensor element (28; 28a).

摘要翻译： 本发明涉及一种用于通过优选设计为X射线源的辐射源（11）来控制药物产品（1），特别是硬明胶胶囊的装置（10; 10a），其包括存储装置（13） 其以不受控制的方式接收产品（1），并且将产品（1）从该产品（1）转移到其中产品（1）布置成使得它们形成至少一排的运输元件（15）。 产品（1）以时钟方式传送到辐射源（11）的辐射区域（25）中，其将产品（1）暴露于放射线，优选垂直于其纵向方向。 用于分离行中的产品（1）的第一停止装置（20）在产品（1）的运输方向（18）上布置在辐射源（11）的上游，并且至少一个传感器元件（28） （28a），其耦合到评估装置（30）捕获通过所述产品（1）的辐射。 根据本发明，通过第一停止装置（20）将至少两个产品（1）与该行分离，同时位于辐射区域（25）中，并且产品（1）的图像被 所述至少一个传感器元件（28; 28a）的装置。

公开(公告)号：US09042515B2

公开(公告)日：2015-05-26

申请号：US14111742

申请日：2012-03-01

申请人： Werner Runft ,  Iulian Maga ,  Jens Schlipf ,  Martin Vogt

发明人： Werner Runft ,  Iulian Maga ,  Jens Schlipf ,  Martin Vogt

IPC分类号： G01N23/083 ,  G01N23/10 ,  G01N33/15 ,  H05G1/02 ,  G01N23/02 ,  G01T7/08 ,  G01T7/10 ,  G01N23/04 ,  A61J3/07 ,  G01N15/00 ,  G01N35/00 ,  G01N15/14

CPC分类号： G01N23/02 ,  A61J3/074 ,  G01N15/1459 ,  G01N23/043 ,  G01N33/15 ,  G01N2015/0019 ,  G01N2035/00564 ,  G01N2223/633 ,  G01N2223/652 ,  G01T7/08 ,  G01T7/10

摘要： The invention relates to a device (10; 10a;10b; 10c; 50) for checking pharmaceutical products (1), in particular hard gelatin capsules, by means of at least one radiation source (30; 60) preferably embodied as an X-ray source, and a conveying device which conveys the products (1) in a clocked manner in a radiation area (31) of the radiation source (30; 60). The radiation emitted by the radiation source (30; 60) penetrating the products (1) preferably perpendicular to the longitudinal axes thereof (2), and the radiation is captured on the side of the products (1) opposite the radiation source (30) by means of at least one sensor element (35) which is coupled to an evaluation device (36). The invention is characterized in that the conveyor device is embodied as a conveyor wheel (15; 15a; 51) which can rotate in a stepped manner about an axis (12; 52), and the products (1) are arranged, while being conveyed in the radiation area (31), in receiving areas (28; 37; 56) of the conveyor wheel (15; 5a; 51).

摘要翻译： 本发明涉及一种用于通过至少一个辐射源（30; 60）检查药物产品（1），特别是硬明胶胶囊的装置（10; 10a; 10b; 10c; 50） 以及输送装置，其以时钟方式在辐射源（30; 60）的辐射区域（31）中传送产品（1）。 由辐射源（30; 60）发射的辐射穿透产品（1），优选地垂直于其纵向轴线（2），并且辐射被捕获在与辐射源（30）相对的产品（1）侧上， 借助于耦合到评估装置（36）的至少一个传感器元件（35）。 本发明的特征在于，输送装置被实施为可以围绕轴线（12; 52）以阶梯式方式旋转的输送轮（15; 15a; 51），并且产品（1）被布置成被输送 在所述辐射区域（31）中，在所述输送轮（15; 5a; 51）的接收区域（28; 37; 56）中。

公开(公告)号：US20140050299A1

公开(公告)日：2014-02-20

申请号：US14111742

申请日：2012-03-01

申请人： Werner Runft ,  Lulian Maga ,  Jens Schlipf ,  Martin Vogt

发明人： Werner Runft ,  Lulian Maga ,  Jens Schlipf ,  Martin Vogt

IPC分类号： G01N23/02

CPC分类号： G01N23/02 ,  A61J3/074 ,  G01N15/1459 ,  G01N23/043 ,  G01N33/15 ,  G01N2015/0019 ,  G01N2035/00564 ,  G01N2223/633 ,  G01N2223/652 ,  G01T7/08 ,  G01T7/10

摘要： The invention relates to a device (10; 10a;10b; 10c; 50) for checking pharmaceutical products (1), in particular hard gelatin capsules, by means of at least one radiation source (30; 60) preferably embodied as an X-ray source, and a conveying device which conveys the products (1) in a clocked manner in a radiation area (31) of the radiation source (30; 60). The radiation emitted by the radiation source (30; 60) penetrating the products (1) preferably perpendicular to the longitudinal axes thereof (2), and the radiation is captured on the side of the products (1) opposite the radiation source (30) by means of at least one sensor element (35) which is coupled to an evaluation device (36). The invention is characterised in that the conveyor device is embodied as a conveyor wheel (15; 15a; 51) which can rotate in a stepped manner about an axis (12; 52), and the products (1) are arranged, whilst being conveyed in the radiation area (31), in receiving areas (28; 37; 56) of the conveyor wheel (15; 5a; 51).

摘要翻译： 本发明涉及一种用于通过至少一个辐射源（30; 60）检查药物产品（1），特别是硬明胶胶囊的装置（10; 10a; 10b; 10c; 50） 以及输送装置，其以时钟方式在辐射源（30; 60）的辐射区域（31）中传送产品（1）。 由辐射源（30; 60）发射的辐射穿透产品（1），优选地垂直于其纵向轴线（2），并且辐射被捕获在与辐射源（30）相对的产品（1）侧上， 借助于耦合到评估装置（36）的至少一个传感器元件（35）。 本发明的特征在于，传送装置被实施为可以围绕轴线（12; 52）以阶梯式方式旋转的传送轮（15; 15a; 51），并且产品（1）被布置成被传送 在所述辐射区域（31）中，在所述输送轮（15; 5a; 51）的接收区域（28; 37; 56）中。

公开(公告)号：US07118915B2

公开(公告)日：2006-10-10

申请号：US10491001

申请日：2001-09-27

申请人： Martin Vogt ,  Arne Skerra

发明人： Martin Vogt ,  Arne Skerra

IPC分类号： C12N15/00

CPC分类号： C07K14/775 ,  A61K38/00 ,  C07K2319/00

摘要： A method for generating a mutein of human apolipoprotein D having detectable affinity to a given non-natural ligand of apolipoprotein D is disclosed, which comprises the steps of: (a) subjecting the apolipoprotein D to mutagenesis at the sequence positions 34 to 38, 60, 62 to 66, 68, 89 to 93, 115, 117 to 121, and 123 resulting in a plurality of muteins of apolipoprotein D; and (b) enriching resulting muteins having binding affinity for a given ligand from the plurality of muteins by selection, and/or isolating said mutein. Muteins of apolipoprotein D obtainable by this method are also disclosed.

摘要翻译： 公开了一种产生具有对载脂蛋白D的给定非天然配体具有可检测亲和力的人载脂蛋白D的突变蛋白的方法，其包括以下步骤：（a）使载脂蛋白D在序列位置34至38,60进行诱变 ，62至66,68,89至93,115,117至121和123，导致多个载脂蛋白D的突变蛋白; 和（b）通过选择和/或分离所述突变蛋白，从所述多个突变蛋白中富集对给定配体具有结合亲和力的所得突变蛋白。 还公开了通过该方法获得的载脂蛋白D的突变蛋白。

公开(公告)号：US20120207272A1

公开(公告)日：2012-08-16

申请号：US13502872

申请日：2010-10-01

申请人： Werner Runft ,  Iulian Maga ,  Ralf Schmied ,  Guenter Liebhart ,  Martin Vogt

发明人： Werner Runft ,  Iulian Maga ,  Ralf Schmied ,  Guenter Liebhart ,  Martin Vogt

IPC分类号： G01N23/04

CPC分类号： G01N23/04 ,  A61J3/074 ,  B65B1/46 ,  B65B3/003 ,  B65B57/145 ,  G01N23/06 ,  G01N23/083 ,  G01N23/087 ,  G01N23/10 ,  G01N2223/04 ,  G01N2223/601

摘要： The invention relates to a sensor device (30; 30a; 30b; 30c) for a packaging machine (100) designed as a capsule filling and sealing machine or for a capsule control device (100a), said device having a positioning element (35; 35a) for positioning a container (c) having a longitudinal axis (15) and filled with a filling material in the region of the sensor device (30; 30a; 30b; 30c) and at least one radiation source (31; 31 a; 3 b) and at least one detector (40; 40a; 40b) for detecting the radiation after said radiation radiates through the container (c). According to the invention, the at least one radiation source (31; 31a; 31b) radiates through the container (c) perpendicular to the longitudinal axis (15) thereof and the positioning element is designed as a tubular or shaft-shaped conveying element (35; 35a) which can be penetrated by the radiation in a radiation cone (38) of the radiation source (31; 31a; 31b).

摘要翻译： 本发明涉及一种设计为胶囊填充封口机或胶囊控制装置（100a）的包装机（100）的传感器装置（30; 30a; 30b; 30c），所述装置具有定位元件（35; 35a），用于在所述传感器装置（30; 30a; 30b; 30c）的区域中定位具有纵向轴线（15）并且填充有填充材料的容器（c）和至少一个辐射源（31; 31a; 3b）和至少一个检测器（40; 40a; 40b），用于在所述辐射辐射穿过容器（c）之后检测辐射。 根据本发明，至少一个辐射源（31; 31a; 31b）通过垂直于其纵向轴线（15）的容器（c）辐射，并且定位元件被设计为管状或轴形输送元件 35; 35a），其可被辐射源（31; 31a; 31b）的辐射锥体（38）中的辐射穿透。