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6 条记录 (耗时 0.017 秒)

    Microneedle
    1.
    发明授权
    Microneedle 有权
    微针

    公开(公告)号：US09462969B2

    公开(公告)日：2016-10-11

    申请号：US13265290

    申请日：2010-04-20

    申请人： Feng Gao ,  Jyrki Kiihamäki ,  Ari Hokkanen ,  Päivi Heimala

    发明人： Feng Gao ,  Jyrki Kiihamäki ,  Ari Hokkanen ,  Päivi Heimala

    IPC分类号： A61M5/32 ,  A61B5/15 ,  A61B5/151 ,  A61M37/00 ,  A61B5/145

    CPC分类号： A61B5/1411 ,  A61B5/14514 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150419 ,  A61B5/150435 ,  A61B5/150511 ,  A61B5/15142 ,  A61B2562/0295 ,  A61M37/0015 ,  A61M2037/003 ,  A61M2037/0053 ,  A61M2037/0061

    摘要： The application relates to microfluidic needles and their manufacturing methods. The microfluidic needle comprises an interface portion containing at least one fluid communication channel, an elongated needle portion (40) projecting away from the interface portion (44), the needle portion having a tip and sidewalls connecting the tip to the interface portion, and at least two microfluidic channels (43 A-B) within the needle portion in fluidic connection with the at least one communication channel, the microfluidic channels being at least partly oriented parallel to the elongated needle portion. According to the application, the microfluidic channels exit the needle portion at the sidewalls of the needle portion. The needle may be fabricated by ALD-assisted silicon micromachining. The needle can be used for injection and/or sampling fluids to/from tissue or individual cells.

    摘要翻译： 本申请涉及微流体针及其制造方法。 所述微流体针包括含有至少一个流体连通通道的界面部分，远离所述界面部分（44）突出的细长针部分（40），所述针部分具有将尖端连接到界面部分的尖端和侧壁， 在所述针部分内与所述至少一个连通通道流体连接的至少两个微流体通道（43AB），所述微流体通道至少部分地定向为平行于所述细长针部分。 根据应用，微流体通道在针部分的侧壁处离开针部分。 针可以通过ALD辅助硅微加工制造。 针可以用于向/从组织或单个细胞注射和/或取样流体。

    MICRONEEDLE
    2.
    发明申请
    MICRONEEDLE 有权

    公开(公告)号：US20120058506A1

    公开(公告)日：2012-03-08

    申请号：US13265290

    申请日：2010-04-20

    申请人： Feng Gao ,  Jyrki Kiihamäki ,  Ari Hokkanen ,  Päivi Heimala

    发明人： Feng Gao ,  Jyrki Kiihamäki ,  Ari Hokkanen ,  Päivi Heimala

    IPC分类号： C12Q1/02 ,  C23F1/02 ,  C12M1/00

    CPC分类号： A61B5/1411 ,  A61B5/14514 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150419 ,  A61B5/150435 ,  A61B5/150511 ,  A61B5/15142 ,  A61B2562/0295 ,  A61M37/0015 ,  A61M2037/003 ,  A61M2037/0053 ,  A61M2037/0061

    摘要： The application relates to microfluidic needles and their manufacturing methods. The microfluidic needle comprises an interface portion containing at least one fluid communication channel, an elongated needle portion (40) projecting away from the interface portion (44), the needle portion having a tip and sidewalls connecting the tip to the interface portion, and at least two microfluidic channels (43 A-B) within the needle portion in fluidic connection with the at least one communication channel, the microfluidic channels being at least partly oriented parallel to the elongated needle portion. According to the application, the microfluidic channels exit the needle portion at the sidewalls of the needle portion. The needle may be fabricated by ALD-assisted silicon micromachining. The needle can be used for injection and/or sampling fluids to/from tissue or individual cells.

    摘要翻译： 本申请涉及微流体针及其制造方法。 所述微流体针包括含有至少一个流体连通通道的界面部分，远离所述界面部分（44）突出的细长针部分（40），所述针部分具有将尖端连接到界面部分的尖端和侧壁， 在所述针部分内与所述至少一个连通通道流体连接的至少两个微流体通道（43AB），所述微流体通道至少部分地定向为平行于所述细长针部分。 根据应用，微流体通道在针部分的侧壁处离开针部分。 针可以通过ALD辅助硅微加工制造。 针可以用于向/从组织或单个细胞注射和/或取样流体。

    Sample port, multi-layer filter, sampling method, and use of a sample port in sampling
    3.
    发明授权
    Sample port, multi-layer filter, sampling method, and use of a sample port in sampling 有权
    采样端口，多层滤波器，采样方法以及采样端口的采样

    公开(公告)号：US08329476B2

    公开(公告)日：2012-12-11

    申请号：US13321804

    申请日：2010-05-21

    申请人： Juha-Pekka Pitkänen ,  Ari Hokkanen ,  Päivi Heimala ,  Jari Kauhaniemi ,  Kai Kolari ,  Pekka Savolahti ,  Jaana Uusitalo

    发明人： Juha-Pekka Pitkänen ,  Ari Hokkanen ,  Päivi Heimala ,  Jari Kauhaniemi ,  Kai Kolari ,  Pekka Savolahti ,  Jaana Uusitalo

    IPC分类号： G01N1/18 ,  B01D35/00

    CPC分类号： G01N1/2035 ,  C12M33/04 ,  C12M33/14 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/255 ,  Y10T436/2575

    摘要： A sample port includes a body equipped with an internal cavity and two plungers arranged moveably in the internal cavity, whereby the plungers can be pressed against each other in the internal cavity, in order to compress a sample. At least one of the plungers can be moved into a reactor in order to collect a sample. The sample port also includes a sample chamber, which is formed by a space remaining between the internal cavity and the plungers. At least one sample-container connection is connected in connection with the internal cavity in order to collect the sample from sample chamber. In addition, the sample port has a filter which is provided to at least either plunger for separating a liquid component of the sample from a solid component and means for leading the liquid component of the sample out of the sample chamber.

    摘要翻译： 样品端口包括具有内腔的主体和可移动地设置在内腔中的两个柱塞，由此柱塞可以在内腔中彼此压靠，以便压缩样品。 柱塞中的至少一个可以移动到反应器中以收集样品。 样品端口还包括样品室，其由保持在内腔和柱塞之间的空间形成。 至少一个样品容器连接件与内部空腔连接，以便从样品室收集样品。 此外，样品端口具有过滤器，该过滤器设置在至少一个柱塞上，用于将样品的液体组分与固体成分分离，以及将样品的液体组分引出样品室的装置。

    SAMPLE PORT, MULTI-LAYER FILTER, SAMPLING METHOD, AND USE OF A SAMPLE PORT IN SAMPLING
    4.
    发明申请
    SAMPLE PORT, MULTI-LAYER FILTER, SAMPLING METHOD, AND USE OF A SAMPLE PORT IN SAMPLING 有权
    样品端口，多层过滤器，采样方法和样品端口采样中的使用

    公开(公告)号：US20120115243A1

    公开(公告)日：2012-05-10

    申请号：US13321804

    申请日：2010-05-21

    申请人： Juha-Pekka Pitkänen ,  Ari Hokkanen ,  Päivi Heimala ,  Jari Kauhaniemi ,  Kai Kolari ,  Pekka Savolahti ,  Jaana Uusitalo

    发明人： Juha-Pekka Pitkänen ,  Ari Hokkanen ,  Päivi Heimala ,  Jari Kauhaniemi ,  Kai Kolari ,  Pekka Savolahti ,  Jaana Uusitalo

    IPC分类号： G01N1/18 ,  B01D35/00

    CPC分类号： G01N1/2035 ,  C12M33/04 ,  C12M33/14 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/255 ,  Y10T436/2575

    摘要： The invention relates to a sample port, filter, and sampling method. The sample port according to the invention comprises a body equipped with an internal cavity and two plungers arranged moveably in this, which can be pressed against each other in the internal cavity, in order to compress a sample, and at least one of which plungers can be moved into a reactor, in order to collect a sample. The sample port also comprises a sample chamber, which is formed by the space remaining between the internal cavity and the plungers, and at least one sample-container connection connected in connection with the internal cavity, in order to collect the sample from sample chamber. In addition, the sample port has filter means adapted to at least either plunger for separating the liquid component of the sample from the solid component and means for leading the liquid component of the sample out of the sample chamber.

    摘要翻译： 本发明涉及采样端口，滤波器和采样方法。 根据本发明的采样端口包括配备有内腔的主体和可移动地布置的两个柱塞，其可在内腔中彼此挤压，以便压缩样品，并且其中至少一个柱塞可以 移入反应器中，以收集样品。 样品端口还包括样品室，其由残留在内部空腔和柱塞之间的空间形成，以及至少一个样品容器连接件，其与内部空腔相连接，以便从样品室收集样品。 此外，样品端口具有适于至少一个柱塞的过滤装置，用于将样品的液体组分与固体组分分离，并将样品的液体组分引导出样品室。