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    SOLID DISPERSION OF AMIDE FLAVOR COMPOUNDS
    4.
    发明申请
    SOLID DISPERSION OF AMIDE FLAVOR COMPOUNDS 审中-公开

    公开(公告)号：US20170245538A1

    公开(公告)日：2017-08-31

    申请号：US15500745

    申请日：2015-07-29

    Applicant: Firmenich SA

    Inventor： Pascal BEAUSSOUBRE ,  Wolfgang FIEBER ,  Stephanie BUDIJONO ,  Valery NORMAND

    IPC: A23L27/00 ,  A23L27/20

    CPC classification number: A23L27/88 ,  A23L27/204 ,  A23V2002/00

    Abstract: Provided herein are methods of improving the dissolution rate in water of a compound of Formula (F) in the form of any one of its stereoisomers or a mixture thereof, and wherein n is an integer from 0 to 2; the dotted line represents a carbon-carbon single or double bond; and each of R1 to R4, when taken independently from each other, represents a hydrogen atom or represents a R5 or OR5 group, R5 representing a C1 to C5 alkyl group; and optionally one of the groups R1 to R4 represents —OH; and/or when R1 and R2 are taken together, and/or R3 and R4 are taken together, represent a OCH2O group, provided said groups taken together are adjacent substituents of the phenyl group.

    SOLUBILIZATION OF A SWEET MODULATOR AND FLAVOR
    6.
    发明申请
    SOLUBILIZATION OF A SWEET MODULATOR AND FLAVOR 审中-公开

    公开(公告)号：US20170188607A1

    公开(公告)日：2017-07-06

    申请号：US15310050

    申请日：2015-04-22

    Applicant: Firmenich SA

    Inventor： Pascal BEAUSSOUBRE ,  Wolfgang FIEBER

    IPC: A23L2/60 ,  A23L27/00 ,  A23L2/56

    CPC classification number: A23L2/60 ,  A23L2/56 ,  A23L27/204 ,  A23L27/2056 ,  A23L27/70 ,  A23L27/88 ,  A23V2002/00

    Abstract: Provided herein is a method of making a concentrated solution of (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one, or a salt or solvate thereof, comprising adding to an aqueous solution: a) a food grade polymer that is soluble in water at or above 0.1% by weight at 20° C. to the aqueous solution; b) a sweetener; and c) (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one wherein the concentration of (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one, or a salt or solvate thereof, is greater than or equal to 1 ppm, by weight of the total weight of the solution, at 3° C. when the pH is less than or equal to 4 or it is greater than or equal to 7 ppm, by weight of the total weight of the solution, at 25° C. when the pH is less than or equal to 4. Further provided herein are solutions and beverages prepared by the methods.

    SOLUTIONS AND DISPERSIONS OF AMIDE COMPOUNDS
    9.
    发明申请
    SOLUTIONS AND DISPERSIONS OF AMIDE COMPOUNDS 审中-公开

    公开(公告)号：US20190104756A1

    公开(公告)日：2019-04-11

    申请号：US16070000

    申请日：2017-02-01

    Applicant: Firmenich SA

    Inventor： Pascal BEAUSSOUBRE ,  Wolfgang FIEBER ,  Howard MUNT

    IPC: A23L27/20 ,  A23L27/21 ,  A23L27/00 ,  C07C235/34 ,  C07C233/11

    Abstract: Provided herein is a process for increasing the dissolution rate of a sparingly water soluble flavor or taste modifying compound in water comprising: a. mixing the compound and a highly water soluble second compound in a water based solution to form a solution or dispersion of the compound; and b. drying the solution or dispersion to form a solution or solid dispersion of the compound wherein the compound has an increased dissolution rate in water as compared to the compound when dissolved in water alone.

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