摘要:
The present invention is to provide a method for obtaining an oligonucleotide such as RNA aptamer having high binding capacity to a target substance with easy-to-use and high purity. The method for obtaining oligonucleotide according to the present invention is as follows:A method for obtaining oligonucleotide comprising the steps of: performing an electrophoresis of a nucleic acid molecule/target substance complex comprising a nucleic acid molecule and a target substance; recovering said nucleic acid molecule/target substance complex; extracting the nucleic acid molecule from said nucleic acid molecule/target substance complex; gene amplifying said nucleic acid molecule.
摘要:
The present invention provides a nucleic acid molecule having an ability to bind to a rabbit anti-mouse IgG antibody, which can be prepared more easily than an antibody and has a binding ability equal to or higher than that of an antibody. The nucleic acid molecule according to the present invention may have the sequences set forth in SEQ ID NOS: 1 to 5. The nucleic acid molecule according to the present invention may be a nucleic acid having an ability to bind to a rabbit IgG antibody, which substantially has homology to its sequence. The nucleic acid molecule according to the present invention may have a binding constant (KD) of 1.18×10−7 (M) or less to the rabbit IgG antibody.
摘要翻译:本发明提供具有与兔抗小鼠IgG抗体结合的能力的核酸分子,其可以比抗体更容易制备并且具有等于或高于抗体的结合能力。 根据本发明的核酸分子可以具有SEQ ID NO:1至5所示的序列。根据本发明的核酸分子可以是具有结合兔IgG抗体的能力的核酸,其中 与其序列基本上具有同源性。 本发明的核酸分子与兔IgG抗体的结合常数(KD)可以为1.18×10 -7(M)以下。
摘要:
The present invention provides a nucleic acid molecule having an ability to bind to a rabbit anti-mouse IgG antibody, which can be prepared more easily than an antibody and has a binding ability equal to or higher than that of an antibody. The nucleic acid molecule according to the present invention may have the sequences set forth in SEQ ID NOS: 1 to 5. The nucleic acid molecule according to the present invention may be a nucleic acid having an ability to bind to a rabbit IgG antibody, which substantially has homology to its sequence. The nucleic acid molecule according to the present invention may have a binding constant (KD) of 1.18×10−7 (M) or less to the rabbit IgG antibody.
摘要翻译:本发明提供具有与兔抗小鼠IgG抗体结合的能力的核酸分子,其可以比抗体更容易制备并且具有等于或高于抗体的结合能力。 根据本发明的核酸分子可以具有SEQ ID NO:1至5所示的序列。根据本发明的核酸分子可以是具有结合兔IgG抗体的能力的核酸,其中 与其序列基本上具有同源性。 本发明的核酸分子与兔IgG抗体的结合常数(KD)可以为1.18×10 -7(M)以下。
摘要:
A highly moisture-resistant liquid crystal display apparatus and a manufacturing method thereof suppresses display deterioration due to the occurrence of image retention without gap controllability and alignment-stability maintenance. The liquid crystal display apparatus includes: a first sealing member arranged at an outer periphery of a liquid crystal layer sandwiched between a pair of substrates; and a second sealing member arranged at an outer periphery of the first sealing member in contact with the pair of substrates. The second sealing member 16 is formed from an alkylsiloxane compound as a main ingredient which is formed into an inorganic film by irradiation with an ultraviolet radiation. The alkylsiloxane compound is a di-alkylsiloxane compound or di-methyl-siloxane compound.
摘要:
An integrated control system includes a main control system controlling a driving system, a main control system controlling a brake system, and a main control system controlling a steering system, an adviser unit generating and providing information to be used at each control system based on environmental information around the vehicle or information related to a driver, an agent unit generating and providing information to be used at each of the main control systems to cause the vehicle to realize a predetermined behavior, and a supporter unit generating and providing information to be used at each of the main control systems based on the current dynamic state of the vehicle.
摘要:
Reactor 1A includes a reaction vessel 10 having an inlet 4 for a to-be-reformed gas 2 and an outlet 8 for a reformed gas 6, a pair of electrodes 12 for plasma generation, a power source 14 for applying a voltage to the pair of electrodes 12, and a catalyst for promoting a reforming reaction, wherein one of the pair of electrodes 12 is a linear electrode 32, the other of the pair of electrodes 12 is a honeycomb electrode 34 made of a conductive ceramics, and the catalyst is loaded on the partition walls of the honeycomb electrode 34, which reactor further includes shielding members 30A placed between the linear electrode 32 and the honeycomb electrode 34, which are protruded toward the gas-introducing end face side of the honeycomb electrode 34 and prevent the inflow of the to-be-reformed gas 2 passing through a zone other than a plasma-generating zone 42.
摘要:
An imaging cartridge has a process unit and a toner box unit formed by integrating a new toner box and a waste toner box. The toner box unit is attachable to and detachable from the process unit. Shutters which open and close a connecting section between the new toner box and a developing device included in the process unit can be opened by manual operation when the toner box unit is attached to the process unit. Shutters and which open and close a connecting section between a cleaning device included in the process unit and the waste toner box are opened when the imaging cartridge is in the process of being moved to a prescribed position in an apparatus body.
摘要:
The present invention relates to an RTM molding device designed to mold a FRP molded body by injecting a resin composition into a mold and by impregnating the molded body therewith. The resin composition is a CCP. A CCP accommodating layer is disposed adjacent to the outer side of the molded body. The layer contains the CCP. The layer is provided with a Vf limit value, the value defined by the curing characteristics of the CCP and the characteristics of dissipation of heat from the CCP into the exterior. A means for separating the molded body is disposed between the body and the layer.
摘要:
An optical sheet laminate body includes: a first optical sheet having a top surface and a bottom surface, of which at least the top surface has asperities including projections and depressions; and a second optical sheet having a top surface and a bottom surface. Summits of the projections on the top surface of the first optical sheet are directly bonded, in a whole region facing the bottom surface of the second optical sheet, to the bottom surface of the second optical sheet without any intermediate material in between.
摘要:
A fixing device for fixing a toner image onto a recording paper includes a heating member for heating the recording paper, a pressing member for pressing the heating member by pressure-applying contact, a casing accommodating the heating member and the pressing member, and being provided with an exit port for discharging the recording paper, and a closing unit added to the exit port for keeping a temperature of the casing. The closing unit has a rotation member, and an opposed member forming a nip region together with the rotation member.