公开(公告)号：US4275056A

公开(公告)日：1981-06-23

申请号：US22594

申请日：1979-03-19

申请人： Fumimaro Takaku ,  Katsuhiro Ogasa ,  Morio Kuboyama ,  Minoru Saito ,  Nobuya Yanai ,  Masayuki Nishida

发明人： Fumimaro Takaku ,  Katsuhiro Ogasa ,  Morio Kuboyama ,  Minoru Saito ,  Nobuya Yanai ,  Masayuki Nishida

IPC分类号： C07K1/22 ,  A61K35/22 ,  A61K38/00 ,  A61K38/16 ,  A61P7/00 ,  A61P35/02 ,  A61P37/00 ,  A61P43/00 ,  C07G99/00 ,  C07K14/00 ,  C07K14/52 ,  G01N33/50 ,  C07G7/00

CPC分类号： C07K14/52 ,  A61K35/22 ,  A61K38/00 ,  Y10S530/834

摘要： A colony-stimulating factor having definite physical and chemical properties and a function of stimulating activity on human bone marrow cells to proliferate and differentiate, thereby forming granulocyte colonies, is obtained from human urine by concentrating the urine with respect to proteins contained therein by adsorption chromatography with silica gel, salting out with ammonium sulfate and other means, then removing impurities by adsorption on cation exchanger, and further purifying by ion exchanging chromatography on anion exchanger, gel filtrating chromatography with highly crosslinked gels, affinitive chromatography with sugar affinitire adsorbents and electrophoresis.

摘要翻译： 具有确定的物理和化学性质以及刺激人骨髓细胞活性增殖和分化，从而形成粒细胞集落的功能的集落刺激因子通过浓缩尿液相对于其中所含蛋白质的吸附色谱从人尿中获得 用硅胶盐析，用硫酸铵等手段进行盐析，然后通过阳离子交换器吸附除去杂质，并进一步通过阴离子交换层析离子交换色谱，高度交联凝胶的凝胶过滤层析，糖亲和吸附剂亲和色谱和电泳进行纯化。

公开(公告)号：US4226847A

公开(公告)日：1980-10-07

申请号：US917254

申请日：1978-06-20

申请人： Katsuhiro Ogasa ,  Morio Kuboyama ,  Minoru Saito ,  Tsutomu Kudo ,  Yoshitsugu Harada ,  Akio Kawashiri ,  Eiji Takahashi

发明人： Katsuhiro Ogasa ,  Morio Kuboyama ,  Minoru Saito ,  Tsutomu Kudo ,  Yoshitsugu Harada ,  Akio Kawashiri ,  Eiji Takahashi

IPC分类号： G01N33/53 ,  A61B10/00 ,  G01N33/15 ,  G01N33/531 ,  G01N33/543 ,  A61K39/00 ,  A61K31/74 ,  G01N31/00 ,  G01N33/16

CPC分类号： G01N33/54313 ,  Y10S436/817 ,  Y10S530/815

摘要： Latex reagents for quantitative assay of a variety of steroid hormones or metabolites thereof which are contained in body fluid or excreted fluid of human beings comprise latex particles which are immunologically sensitized with a conjugate selected from a variety of steroid-serum albumin conjugates in which the steroid to be detected is bonded to serum albumin in a very small ratio ranging from 0.5 to 7 molecules per 1 molecule of the serum albumin used.Sensitization of latex particles with such a conjugate is performed using a limited amount dependent on the bonding ratio of steroid molecules per molecule of serum albumin in the conjugate and the particle size of the latex used.The latex reagents show very high sensitivity amounting to 0.2-0.04 nmole steroid equivalent/ml.

摘要翻译： 用于定量测定体液或人体排泄液中各种类固醇激素或其代谢物的胶乳试剂包含用选自多种类固醇 - 血清白蛋白缀合物的缀合物进行免疫敏化的胶乳颗粒，其中类固醇 要被检测的是以每1分子所用血清白蛋白0.5至7个分子的非常小的比例与血清白蛋白结合。 使用这样的缀合物对胶乳颗粒进行敏化，其取决于缀合物中每分子血清白蛋白的类固醇分子的键合比例和所使用的胶乳的粒径。 乳胶试剂显示非常高的灵敏度，达到0.2-0.04nmol类固醇当量/ ml。

公开(公告)号：US4100022A

公开(公告)日：1978-07-11

申请号：US727653

申请日：1976-09-29

申请人： Katsuhiro Ogasa ,  Morio Kuboyama ,  Minoru Saito ,  Kazuhiro Nagata

发明人： Katsuhiro Ogasa ,  Morio Kuboyama ,  Minoru Saito ,  Kazuhiro Nagata

IPC分类号： A61K38/00 ,  A61K35/50 ,  A61P35/02 ,  C12K9/00

CPC分类号： A61K35/50

摘要： A process for preparing a therapeutic agent characterized by preculturing human amnion cells isolated from human amnion by trypsinization or human amnion cells obtained by subculturing the isolated cells in a medium containing calf or bovine fetal serum at least one time for 1 to 5 days to form a monolayer, removing the medium, adding a medium containing 0.5 to 20 mg of human serum albumin per 1 ml of medium thereto and culturing it for 3 to 6 days, dialyzing the culture liquid against diluted buffer or water, and filtering the dialyzed culture liquid through a bacterial filter thereby obtaining a germ free liquid agent.

摘要翻译： 一种治疗剂的制备方法，其特征在于，通过胰蛋白酶消化法分离人羊膜中的人羊膜细胞，或通过将分离的细胞在含有小牛或牛胎儿血清的培养基中传代培养获得的人羊膜细胞，至少一次进行1至5天，形成 单层，除去培养基，每1ml培养基中加入含有0.5〜20mg人血清白蛋白的培养基，培养3〜6天，将培养液用稀释的缓冲液或水透析，并将透析的培养液通过 细菌过滤器，从而获得无菌液体剂。

公开(公告)号：US4645667A

公开(公告)日：1987-02-24

申请号：US566074

申请日：1983-12-27

申请人： Yoshiyuki Hashimoto ,  Tomohiro Toida ,  Kazunori Sekine ,  Minoru Saito ,  Takuji Kawashima ,  Morio Kuboyama

发明人： Yoshiyuki Hashimoto ,  Tomohiro Toida ,  Kazunori Sekine ,  Minoru Saito ,  Takuji Kawashima ,  Morio Kuboyama

IPC分类号： A61K35/74 ,  A61P35/00 ,  C12P1/04 ,  A61K39/02 ,  A61K35/78

CPC分类号： C12P1/04

摘要： This invention relates to an antitumor agent comprising as a main ingredient a chemically purified cell walls of microorganisms belonging to genus Bificobacterium having physical integrity of cell wall structure thereof, obtained without being subjected to chemical and/or physical destruction of said cell wall during removal of intracellular substances of said cell, and a process for manufacturing the same, which comprises the steps of; (a) treating said cells with surfactants, (b) treating said cells with proteases, nucleases, organic solvents and dilute acid, to remove intracellular substances out of said cells without destruction thereof, and (c) separating a chemically purified cell walls having physical integrity of cell wall structure thereof.

摘要翻译： 本发明涉及一种抗肿瘤剂，其包含作为主要成分的化学纯化的细胞壁，所述微生物属于具有细胞壁结构的物理完整性的微生物，其细胞壁结构具有物理完整性，而不会在除去所述细胞壁时被化学和/或物理破坏所述细胞壁 所述细胞的细胞内物质及其制造方法，包括以下步骤： （a）用表面活性剂处理所述细胞，（b）用蛋白酶，核酸酶，有机溶剂和稀酸处理所述细胞，以除去所述细胞中的细胞内物质而不破坏细胞，和（c）分离具有物理 细胞壁结构的完整性。

公开(公告)号：US4054648A

公开(公告)日：1977-10-18

申请号：US496814

申请日：1974-08-12

申请人： Taro Nagasawa ,  Morio Kuboyama ,  Joji Ono ,  Minoru Saito ,  Tsutomu Kudo ,  Eiji Takahashi ,  Kazuyoshi Doi ,  Kazuhiro Nagata

发明人： Taro Nagasawa ,  Morio Kuboyama ,  Joji Ono ,  Minoru Saito ,  Tsutomu Kudo ,  Eiji Takahashi ,  Kazuyoshi Doi ,  Kazuhiro Nagata

IPC分类号： A61K35/50 ,  A61K38/00 ,  A61P35/02

CPC分类号： A61K35/50

摘要： Therapeutic agents are prepared by:A. grinding placenta with water or diluted physiological saline to form an emulsion, and acidifying the emulsion with a mixture of aqueous acetic acid and hydrochloric acid, to 0.5 to 2.0N;B. heating the acidified emulsion;C. cooling the emulsion, removing insoluble protein by centrifugation, neutralizing the emulsion with an alkali solution, centrifuging said emulsion to remove insoluble matter and collecting a clear supernatant;D. concentrating the supernatant, and dialyzing the resulting concentrated liquid through a dialysis membrane, or filtrating said supernatant through a membrane filter to obtain a dialyzed fluid or filtrate;E. subjecting the dialyzed fluid or filtrate, after concentration to column chromatography, to obtain any one of fractions, of 0.96 - 1.82 in distribution coefficient with Sephadex G-25, of 0.35 - 1.24 with Sephadex G-15, or of 0.35 - 1.25 with Sephadex G-10; andF. lyophilizing the fraction.

摘要翻译： 治疗剂通过以下方法制备：

公开(公告)号：US08682603B2

公开(公告)日：2014-03-25

申请号：US13158162

申请日：2011-06-10

申请人： Hiroyuki Maehara ,  Tomonori Nishida ,  Shigeki Katayama ,  Yukihiko Maede ,  Minoru Saito ,  Wataru Yamamori ,  Jun Takehara ,  Takaya Shono

发明人： Hiroyuki Maehara ,  Tomonori Nishida ,  Shigeki Katayama ,  Yukihiko Maede ,  Minoru Saito ,  Wataru Yamamori ,  Jun Takehara ,  Takaya Shono

IPC分类号： G06F19/00

CPC分类号： H04Q9/00 ,  H04Q2209/845

摘要： A substation instrument control system is disclosed. The substation instrument control system includes a plurality of transformers that generate a plurality of waveform signals representing electric properties of a substation instrument main body. A merging unit is communicatively coupled to the plurality of transformers and includes a signal processing unit and a control unit. The signal processing unit receives the plurality of waveform signals from the plurality of transformers and converts the plurality of waveform signals to a digital signal. The control unit controls operation of the signal processing unit using a setting data. An intelligent electronic device is communicatively coupled to the merging unit and receives the digital signal from the merging unit.

摘要翻译： 公开了变电站仪表控制系统。 变电站仪表控制系统包括产生表示变电站仪器主体的电气特性的多个波形信号的多个变压器。 合并单元通信地耦合到多个变压器，并且包括信号处理单元和控制单元。 信号处理单元从多个变压器接收多个波形信号，并将多个波形信号转换为数字信号。 控制单元使用设定数据来控制信号处理单元的动作。 智能电子设备通信地耦合到合并单元并从合并单元接收数字信号。

公开(公告)号：US20120189257A1

公开(公告)日：2012-07-26

申请号：US13397397

申请日：2012-02-15

申请人： Minoru KASAHARA ,  Minoru Saito ,  Yasuo Nakajima ,  Hiroki Tanaka

发明人： Minoru KASAHARA ,  Minoru Saito ,  Yasuo Nakajima ,  Hiroki Tanaka

IPC分类号： G02B6/44 ,  G02B6/02

CPC分类号： C03C25/106 ,  G02B6/02395 ,  G02B6/4408 ,  G02B6/4411

摘要： According to the present invention, there is provided an optical fiber, an optical fiber ribbon and an optical fiber cable that reduce both the increase in transmission loss and the decrease in strength. According to an embodiment of the present invention, there is provided an optical fiber in which an outer circumferential surface of an optical fiber is coated with a primary coating layer. In the optical fiber, the primary coating layer includes a ultraviolet curable resin, and the ultraviolet curable resin contains 0.05 or more and 0.75 or less parts by weight of a reactive silane coupling agent and 0.05 or more and 0.75 or less parts by weight of an unreactive silane coupling agent.

摘要翻译： 根据本发明，提供一种减少传输损耗增加和强度降低的光纤，光纤带和光纤电缆。 根据本发明的实施例，提供了一种光纤，其中光纤的外圆周表面涂覆有初级涂层。 在光纤中，初级涂层包括紫外线固化树脂，紫外线固化树脂含有0.05重量％以上且0.75重量份以下的活性硅烷偶联剂，0.05重量份以下且0.75重量份以下的 非反应性硅烷偶联剂。

公开(公告)号：US08018097B2

公开(公告)日：2011-09-13

申请号：US12443980

申请日：2007-10-02

申请人： Minoru Saito ,  Hiroyuki Maehara ,  Shiro Maruyama

发明人： Minoru Saito ,  Hiroyuki Maehara ,  Shiro Maruyama

IPC分类号： H02B1/24

CPC分类号： H01H9/563 ,  H01H2300/03 ,  H02J13/0086 ,  Y02B70/3241 ,  Y02B90/224 ,  Y04S20/14 ,  Y04S20/227 ,  Y10T307/74 ,  Y10T307/951

摘要： A switching control system of circuit breaker, including at least: one switching control unit per circuit breaker, each of which inputs electrical quantity of power system voltage and main circuit current, state quantity of a circuit breaker, and an opening command signal or closing command signal of the circuit breaker, and performs control to cause the circuit breaker to open or close at a desired phase of the power system voltage or main circuit current; and a display operation unit connected with the switching control unit via a communication network and performs display operation to operate and monitor the operation and state of the switching control unit of circuit breaker. The switching control unit includes a first area for causing the circuit breaker to open or close at a desired phase of the power system voltage or current; and a second area for transmitting/receiving information via the communication network.

摘要翻译： 一种断路器的开关控制系统，至少包括：每个断路器的一个开关控制单元，每个断路器输入电力系统电压和主电路电流的电量，断路器的状态量以及开启指令信号或闭合指令 信号，并且执行控制以使断路器在电力系统电压或主电路电流的期望相位处打开或关闭; 以及显示操作单元，其经由通信网络与切换控制单元连接，并执行显示操作以操作和监视断路器的切换控制单元的操作和状态。 切换控制单元包括用于使断路器在电力系统电压或电流的期望相位处打开或关闭的第一区域; 以及经由通信网络发送/接收信息的第二区域。

公开(公告)号：US20100187916A1

公开(公告)日：2010-07-29

申请号：US12445640

申请日：2007-10-12

申请人： Minoru Saito

发明人： Minoru Saito

IPC分类号： H01H33/59 ,  G06F19/00

CPC分类号： G01R33/04 ,  G01R33/0029 ,  G01R33/02 ,  G01R33/028 ,  Y10T307/944

摘要： The present invention provides a magnetic flux measuring device and magnetic flux measuring method for stationary induction electrical apparatus which can accurately measure the magnetic flux without being influenced by the DC offset component which superimposes on the measurement system, and can constantly and continuously measure the magnetic flux without setting a limit in the magnetic flux measurement period. The magnetic flux measuring method which measures a magnetic flux of a stationary induction electrical apparatus 2 using a voltage waveform of the stationary induction electrical apparatus 2, wherein the magnetic flux 151 of the stationary induction electrical apparatus 2 is determined by the steps of: inputting a voltage waveform 121 of the stationary induction electrical apparatus 2 into a negative-feedback amplification means 14 of which feedback circuit is constructed by a low pass filter; and integrating output of the negative-feedback amplification means 14 by integration means 15.

摘要翻译： 本发明提供了一种用于固定式感应电气设备的磁通量测量装置和磁通量测量方法，其可以在不受叠加在测量系统上的直流偏移分量的影响下精确地测量磁通量，并且可以持续和连续地测量磁通量 而不设置磁通量测量周期的限制。 使用静止感应电气设备2的电压波形来测量静止感应电气设备2的磁通量的磁通量测量方法，其中静止感应电气设备2的磁通量151通过以下步骤确定：输入 静态感应电气设备2的电压波形121变为负反馈放大装置14，其反馈电路由低通滤波器构成; 并通过积分装置15积分负反馈放大装置14的输出。

公开(公告)号：US20080306845A1

公开(公告)日：2008-12-11

申请号：US12123737

申请日：2008-05-20

申请人： Midori MURAYAMA ,  Chikara Kishi ,  Hidenao Ubukata ,  Minoru Saito ,  Minoru Sakai ,  Naoki Wakasugi ,  Nobumitsu Samukawa ,  Toshiyuki Shimizu ,  Yasushi Ogawa ,  Yoshiroh Someya ,  Ryosuke Sako ,  Kazumi Hanada ,  Kentaroh Murakawa

发明人： Midori MURAYAMA ,  Chikara Kishi ,  Hidenao Ubukata ,  Minoru Saito ,  Minoru Sakai ,  Naoki Wakasugi ,  Nobumitsu Samukawa ,  Toshiyuki Shimizu ,  Yasushi Ogawa ,  Yoshiroh Someya ,  Ryosuke Sako ,  Kazumi Hanada ,  Kentaroh Murakawa

IPC分类号： G06Q10/00 ,  G06Q30/00

CPC分类号： G06Q40/10 ,  G06K15/00 ,  G06Q20/102 ,  G06Q30/0283 ,  G06Q30/04 ,  G06Q40/02

摘要： A charge managing system including an image forming apparatus and a charge managing server is provided. The image forming apparatus includes plural applications each configured for executing a specific process on input data, a counter unit that counts a number of result items output as a result of executing at least one of the applications, a count value storage unit that stores a count value corresponding to the number of result items counted by the counter unit, and a storage area setting unit that secures a plurality of storage areas within the count value storage unit each of which storage areas is configured for storing a corresponding count value obtained for each of the applications. The charge managing server manages charging a fee for using the image forming apparatus based on the corresponding count value stored in each of the storage areas secured for each of the applications.

摘要翻译： 提供了包括图像形成装置和电荷管理服务器的电荷管理系统。 图像形成装置包括多个应用，每个应用被配置用于对输入数据执行特定处理;对作为执行至少一个应用程序的结果输出的结果项数进行计数的计数器单元，存储计数的计数值存储单元 对应于由计数器单元计数的结果项目的数量的值;以及存储区域设置单元，其确保计数值存储单元内的多个存储区域，每个存储区域被配置为存储针对每个存储区域获得的相应计数值 应用程序。 收费管理服务器根据存储在为每个应用确保的每个存储区域中的相应计数值来管理使用图像形成装置的费用。