摘要:
Substrate probe capable of detecting enzyme activity with high accuracy and a method for detecting the enzyme activity by a multi nuclear magnetic resonance method using the substrate probe. Multi-dimensional nuclear magnetic resonance is performed by using a substrate probe, which is used for measuring enzyme activity by a multi-dimensional nuclear magnetic resonance method and characterized by containing a enzyme recognition site that is selectively recognized by an active-state enzyme, as at least one constitutional unit, and a group to which at least three nuclear magnetic resonance active nuclei each having a nuclear spin and a different resonance frequency are connected, being present specifically to the enzyme recognition, thereby detecting presence of the substrate probe and the enzyme activity. Alternatively, imaging of the enzyme activity is performed by a multi-dimensional nuclear resonance imaging method.
摘要:
Substrate probe capable of detecting enzyme activity with high accuracy and a method for detecting the enzyme activity by a multi nuclear magnetic resonance method using the substrate probe. Multi-dimensional nuclear magnetic resonance is performed by using a substrate probe, which is used for measuring enzyme activity by a multi-dimensional nuclear magnetic resonance method and characterized by containing a enzyme recognition site that is selectively recognized by an active-state enzyme, as at least one constitutional unit, and a group to which at least three nuclear magnetic resonance active nuclei each having a nuclear spin and a different resonance frequency are connected, being present specifically to the enzyme recognition, thereby detecting presence of the substrate probe and the enzyme activity. Alternatively, imaging of the enzyme activity is performed by a multi-dimensional nuclear resonance imaging method.
摘要:
The present invention provides a method for measuring nuclear magnetic resonance that employs a compound in which a plurality of nuclei is labeled with isotopes as a probe agent, highly selectively and highly sensitively obtains a nuclear magnetic resonance signal of the above described probe agent, and can attach a spatial positional information to the above described nuclear magnetic resonance signal, and an apparatus therefore.
摘要:
To produce a labeled compound for a selected biological substance not using a radioisotope atom which has a risk of exposure to radioactivity and limitation on handling time but using a stable isotope atom; and that the labeled compound can be measured with good sensitivity separably from naturally occurring compounds of the selected biological substance which are substituted with the stable isotope atom. Choline as a biological substance is labeled by substituting the nitrogen atom of the quaternary ammonium group and all the carbon atoms of the methyl group attached to the nitrogen atom with respective isotopes 15N and 13C and used as a diagnostic agent.
摘要:
The present invention provides a method for measuring nuclear magnetic resonance that employs a compound in which a plurality of nuclei is labeled with isotopes as a probe agent, highly selectively and highly sensitively obtains a nuclear magnetic resonance signal of the above described probe agent, and can attach a spatial positional information to the above described nuclear magnetic resonance signal, and an apparatus therefore.
摘要:
The nucleic acid probe of the invention is a nucleic acid probe for detecting a trace amount of target nucleic acid highly sensitively, highly accurately, and highly quickly, and is designed so that the nucleic acid probe undergoes a conformational change after hybridization to the target nucleic acid and that the nucleic acid probe, which underwent the conformational change, has a decreased binding strength of hybridization and dissociates from the target nucleic acid, where the conformational change comprises forming a self-cleaving nucleic acid enzyme intramolecularly and the self-cleaving nucleic acid enzyme has cleavage activity toward a cleavage portion within the nucleic acid probe's own molecule.
摘要:
A communication control method accomplishes minimum bandwidth guarantee and maximum bandwidth restriction and further allocates an extra-bandwidth in accordance with user's contact bandwidth. Fixed-length packets are once stored in corresponding partitions of a buffer in accordance with connection information contained in the packets and then transmits the packets from the storage sections in succession. Retrieval of a connection where the number of transmitted packets does not reach a lower-limit throughput and a packet to be transmitted exists in the corresponding partition is made with first priority, and retrieval is further made in order for a connection where the number of transmitted packets does not reach an intermediate throughput and a connection where the number of transmitted packets does not reach an upper-limit throughput. If the retrieval shows a hit connection, the packets are transmitted from the corresponding partition and one-time retrieval comes to an end.
摘要:
In an air bag apparatus for a passenger seat, an air bag door has three layers: a door base member, a shell and a foam layer charged between the door base member and the shell. A groove-shaped rib is formed in a rearward end-side portion of the door base member of the air bag door. A grommet is fixed at each of the opposite ends of the rib. A strap formed of a looped resin-made cord formed by knotting the two end portions of the cord is laid in the rib, extending through the grommets. The strap is covered with a heat-shrink tube that prevents degradation of the strap due to influence of a component material of the foam layer.
摘要:
This invention is directed to image reading capable of suppressing EMI unwanted radiation while maintaining image quality. To accomplish this, the following processing is executed when reading an original image by a photoelectric transducer. More specifically, a first driving signal where SSCG spread modulation is applied, and a second driving signal where no SSCG spread modulation is applied are generated from a reference signal. Either the first or second driving signal is selected, and a timing signal for reading the original image is generated based on the selected driving signal. The image signal obtained by the photoelectric transducer is latched using the timing signal. The latched image signal is transferred for subsequent image processing. Upon reading a one-line image original, the second driving signal is selected till the completion of the latch operation, and after the latch operation, the first driving signal is selected for an image signal transfer operation.
摘要:
A semiconductor device according to the present invention includes: a semiconductor chip; and memory and logic sections formed on the semiconductor chip. The memory section includes: an array of memory cells; a sense amplifier circuit; and memory interconnects respectively provided in a number n (where n is a positive integer) of interconnect layers. The logic section includes logic circuits having logic interconnects respectively provided in a number n+m (where m is a positive integer) of interconnect layers. A metal layer is formed in one of (n+1)th to (n+m)th interconnect layers, covers the array of memory cells and supplies a predetermined potential to the memory section.