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公开(公告)号：US20180265860A1
公开(公告)日：2018-09-20
申请号：US15985771
申请日：2018-05-22
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Lin Chen , Bing Zhang , Klaus Hochleitner , Rong Hou , Yanju Wang
IPC: C12N15/10 , B01J20/28 , B01J20/281 , B01J20/10 , C07H1/08 , C07H21/00 , C07H21/02 , C07H21/04 , C07H1/06
CPC classification number: C12N15/1017 , B01J20/103 , B01J20/28023 , B01J20/28038 , B01J20/281 , B01J2220/82 , C07H1/06 , C07H1/08 , C07H21/00 , C07H21/02 , C07H21/04
Abstract: A method comprises: sorbing a sample solution comprising nucleic acids to a sample receiving portion of a quartz fiber filter by contacting the sample solution with the sample receiving portion; and washing the sample receiving portion while keeping most of nucleic acids around the sample receiving portion by flowing a wash solution through the sample receiving portion under a wicking force directed away from the sample receiving portion. An associated apparatus is also provided.
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2.发明申请METHOD FOR STERILIZING MEMBRANE COMPRISING AND OXIDOREDUCTASE ENZYME AND ASSOCIATED BIOSENSOR 有权灭菌膜和氧化还原酶和相关生物传感器的方法公开(公告)号：US20150151013A1
公开(公告)日：2015-06-04
申请号：US14402473
申请日：2013-05-29
Applicant: GENERAL ELECTRIC COMPANY
CPC classification number: A61L2/081 , A61L2/0035 , C12Q1/005 , C12Q1/006 , C12Q1/26 , C12Q1/54 , G01N2333/904
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme in an environment having a relative humidity, comprises: irradiating the membrane comprising an oxidoreductase enzyme with gamma radiation under vacuum at a relative humidity lower than the relative humidity of the environment. Associated biosensors are also described.
Abstract translation: 在具有相对湿度的环境中对包含氧化还原酶的膜进行灭菌的方法包括：在低于环境相对湿度的相对湿度下，在真空下照射含有氧化还原酶的膜。 还描述了相关生物传感器。
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公开(公告)号：US10683496B2
公开(公告)日：2020-06-16
申请号：US15985771
申请日：2018-05-22
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Lin Chen , Bing Zhang , Klaus Hochleitner , Rong Hou , Yanju Wang
IPC: C07H21/00 , C12N15/10 , B01J20/10 , B01J20/28 , B01J20/281 , C07H1/06 , C07H1/08 , C07H21/02 , C07H21/04
Abstract: A method comprises: sorbing a sample solution comprising nucleic acids to a sample receiving portion of a quartz fiber filter by contacting the sample solution with the sample receiving portion; and washing the sample receiving portion while keeping most of nucleic acids around the sample receiving portion by flowing a wash solution through the sample receiving portion under a wicking force directed away from the sample receiving portion. An associated apparatus is also provided.
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公开(公告)号：US10576452B2
公开(公告)日：2020-03-03
申请号：US15564265
申请日：2016-03-01
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Lianghua Lu , Lin Chen , Jie Gao , Zhida Pan , Wenqing Peng , Tobias E. Soderman
IPC: B01J2/06 , B01J2/08 , B01J2/04 , B01J20/24 , B01J13/00 , B01J20/26 , B01J20/28 , B01J20/285 , B01J20/286 , B01J4/00 , B01J20/281 , B01J20/30 , C07K1/16 , C07K1/18 , C07K1/22
Abstract: A method includes spraying a liquid including polymer and a gas substantially inert to the liquid respectively from a first and second orifice of a nozzle into air to form mist of beads. The beads then are collected with a collecting medium at a temperature in a range from about −10° C. to about 80° C. The collecting medium includes at least one of water and alcohols.
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公开(公告)号：US20180154026A1
公开(公告)日：2018-06-07
申请号：US15884310
申请日：2018-01-30
Applicant: General Electric Company
CPC classification number: A61L2/081 , A61L2/0035 , C12M41/32 , C12Q1/006 , C12Q1/26
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme, comprises: irradiating with gamma radiation the membrane comprising an oxidoreductase enzyme soaked in an aqueous buffer solution. Associated biosensors and bioreactors are also described.
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Patent Agency Ranking
公开(公告)号：US20160340669A1
公开(公告)日：2016-11-24
申请号：US15231082
申请日：2016-08-08
Applicant: General Electric Company
Inventor： Lin Chen , BING Zhang , Klaus Hochleitner , Rong Hou , Yanju Wang
CPC classification number: C12N15/1017 , B01J20/103 , B01J20/28023 , B01J20/28038 , B01J20/281 , B01J2220/82 , C07H1/06 , C07H1/08 , C07H21/00 , C07H21/02 , C07H21/04
Abstract: A method comprises: sorbing a sample solution comprising nucleic acids to a sample receiving portion of a quartz fiber filter by contacting the sample solution with the sample receiving portion; and washing the sample receiving portion while keeping most of nucleic acids around the sample receiving portion by flowing a wash solution through the sample receiving portion under a wicking force directed away from the sample receiving portion. An associated apparatus is also provided.
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公开(公告)号：US09441220B2
公开(公告)日：2016-09-13
申请号：US14364436
申请日：2012-12-20
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Lin Chen , Bing Shang , Klaus Hochleitner , Rong Hou , Yanju Wang
CPC classification number: C12N15/1017 , B01J20/103 , B01J20/28023 , B01J20/28038 , B01J20/281 , B01J2220/82 , C07H1/06 , C07H1/08 , C07H21/00 , C07H21/02 , C07H21/04
Abstract: A method comprises: sorbing a sample solution comprising nucleic acids to a sample receiving portion of a quartz fiber filter by contacting the sample solution with the sample receiving portion; and washing the sample receiving portion while keeping most of nucleic acids around the sample receiving portion by flowing a wash solution through the sample receiving portion under a wicking force directed away from the sample receiving portion. An associated apparatus is also provided.
Abstract translation: 一种方法包括：通过使样品溶液与样品接收部分接触，将含有核酸的样品溶液吸附到石英纤维过滤器的样品接收部分; 以及通过在远离样品接收部分的芯吸力下使洗涤溶液流过样品接收部分，同时将样品接收部分周围的大部分核酸保持在一起而洗涤样品接收部分。 还提供了一种相关联的装置。
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公开(公告)号：US10369238B2
公开(公告)日：2019-08-06
申请号：US15884310
申请日：2018-01-30
Applicant: General Electric Company
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme, comprises: irradiating with gamma radiation the membrane comprising an oxidoreductase enzyme soaked in an aqueous buffer solution. Associated biosensors and bioreactors are also described.
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公开(公告)号：US20190160447A1
公开(公告)日：2019-05-30
申请号：US16306749
申请日：2017-06-22
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Lin Chen , Jie Gao , Qiongqiong Huang
Abstract: A method for forming polymer microparticles is disclosed. The method comprises spraying a liquid comprising a thermally-gelling polymer from a first orifice of a nozzle into air to form gelled microparticles, and collecting the gelled microparticles with a collecting device. The nozzle is positioned to have a central axis of the first orifice at a tilt angle in a range from about 10 degrees to about 170 degrees relative to a direction of gravity. The collecting device comprises at least two collecting units at different distances from the first orifice of the nozzle in a horizontal direction perpendicular to the direction of gravity. Each of the collecting unit is loaded with a liquid collecting medium. A system for forming polymer microparticles is also disclosed.
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公开(公告)号：US10000751B2
公开(公告)日：2018-06-19
申请号：US15231082
申请日：2016-08-08
Applicant: General Electric Company
Inventor： Lin Chen , Bing Zhang , Klaus Hochleitner , Rong Hou , Yanju Wang
IPC: C07H21/00 , C12N15/10 , B01J20/10 , B01J20/28 , B01J20/281 , C07H1/06 , C07H1/08 , C07H21/02 , C07H21/04
CPC classification number: C12N15/1017 , B01J20/103 , B01J20/28023 , B01J20/28038 , B01J20/281 , B01J2220/82 , C07H1/06 , C07H1/08 , C07H21/00 , C07H21/02 , C07H21/04
Abstract: A method comprises: sorbing a sample solution comprising nucleic acids to a sample receiving portion of a quartz fiber filter by contacting the sample solution with the sample receiving portion; and washing the sample receiving portion while keeping most of nucleic acids around the sample receiving portion by flowing a wash solution through the sample receiving portion under a wicking force directed away from the sample receiving portion. An associated apparatus is also provided.
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