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公开(公告)号:US20210071212A1
公开(公告)日:2021-03-11
申请号:US16915454
申请日:2020-06-29
Applicant: Genomatica, Inc.
Inventor: Andreas W. Schirmer , Haibo Wang , Stephen B. Del Cardayre , Zhihao Hu , Louis G. Hom , Baolong Zhu , Cindy Chang , Emanuela E. Popova
Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
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公开(公告)号:US10711288B2
公开(公告)日:2020-07-14
申请号:US14897285
申请日:2014-06-16
Applicant: GENOMATICA, INC.
Inventor: Andreas W. Schirmer , Haibo Wang , Stephen B. Del Cardayre , Zhihao Hu , Louis G. Hom , Baolong Zhu , Cindy Chang , Emanuela E. Popova
IPC: C12P7/64 , C12N1/21 , C12N9/04 , C12N9/02 , C12N9/88 , C12N9/10 , C12N9/06 , C12N15/53 , C12N15/54 , C12N9/60 , C07K19/00 , C12P7/42 , C12N15/62 , C12P7/18 , C12N15/52
Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
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公开(公告)号:US11359216B2
公开(公告)日:2022-06-14
申请号:US16889211
申请日:2020-06-01
Applicant: Genomatica, Inc.
Inventor: Andreas W. Schirmer , Noah Helman , Haibo Wang , Zhihao Hu , Vikranth Arlagadda , Alma Itzel Ramos-Solis , Elizabeth Clarke
Abstract: The disclosure relates to fatty diols and recombinant microorganisms for producing them. More particularly, the disclosure relates to recombinant microorganisms engineered to produce fatty diols via fermentation. Further encompassed is a process that uses the microorganisms to produce fatty diols from a simple carbon source.
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公开(公告)号:US12188068B2
公开(公告)日:2025-01-07
申请号:US17229543
申请日:2021-04-13
Applicant: Genomatica, Inc.
Inventor: Stephen B. Del Cardayre , Andreas W. Schirmer , Myong Ko , Haibo Wang
Abstract: The present disclosure relates to chemo-enzymatic processes for the preparation of lactones (including, e.g., macrolactones, γ-lactones, and δ-lactones) and/or macrocyclic ketones, which are compounds of industrial value, for example, for use as fragrance ingredients. The chemo-enzymatic processes combine the in vivo microbial production of fatty acid derivatives and the subsequent ex vivo synthetic transformation of the fatty acid derivatives to provide the lactones and macrocyclic ketones.
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公开(公告)号:US20240158326A1
公开(公告)日:2024-05-16
申请号:US18334745
申请日:2023-06-14
Applicant: Genomatica, Inc.
Inventor: Myong KO , Haibo Wang , Patricia J. Cole , Perry Y. Liao , Simon Li
CPC classification number: C07C29/88 , C07C29/172
Abstract: The disclosure relates to downstream processing of fatty alcohol (FALC) and provides a novel purification method that provides FALC at high purity and yield.
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公开(公告)号:US11168046B2
公开(公告)日:2021-11-09
申请号:US16739645
申请日:2020-01-10
Applicant: Genomatica, Inc.
Inventor: Haibo Wang
IPC: C07C33/035 , C07H15/10
Abstract: The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds and derivatives thereof which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc.
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公开(公告)号:US20210071207A1
公开(公告)日:2021-03-11
申请号:US16889211
申请日:2020-06-01
Applicant: Genomatica, Inc.
Inventor: Andreas W. Schirmer , Noah HELMAN , Haibo Wang , Zhihao Hu , Vikranth Arlagadda , Alma Itzel RAMOS-SOLIS , Elizabeth Clarke
Abstract: The disclosure relates to fatty diols and recombinant microorganisms for producing them. More particularly, the disclosure relates to recombinant microorganisms engineered to produce fatty diols via fermentation. Further encompassed is a process that uses the microorganisms to produce fatty diols from a simple carbon source.
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公开(公告)号:US11053184B2
公开(公告)日:2021-07-06
申请号:US14773149
申请日:2014-03-07
Applicant: GENOMATICA, INC.
Inventor: Myong K. Ko , Haibo Wang , Patricia J. Cole , Perry Y. Liao , Simon Li
Abstract: The disclosure relates to downstream processing of fatty alcohol (FALC) and provides a novel purification method that provides FALC at high purity and yield.
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公开(公告)号:US11008597B2
公开(公告)日:2021-05-18
申请号:US15301754
申请日:2015-04-10
Applicant: Genomatica, Inc.
Inventor: Stephen B. Del Cardayre , Andreas W. Schirmer , Myong Ko , Haibo Wang
Abstract: The present disclosure relates to processes that combine microbial production of organic intermediates and subsequent synthetic transformation to provide compounds of industrial value, including compounds used in fragrances.
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公开(公告)号:US11981952B2
公开(公告)日:2024-05-14
申请号:US16915454
申请日:2020-06-29
Applicant: Genomatica, Inc.
Inventor: Andreas W. Schirmer , Haibo Wang , Stephen B. Del Cardayre , Zhihao Hu , Louis G. Hom , Baolong Zhu , Cindy Chang , Emanuela E. Popova
IPC: C12P7/6409 , C12N1/21 , C12N9/02 , C12N9/04 , C12N15/52 , C12N15/62 , C12P7/18 , C12P7/42 , C12P7/6436
CPC classification number: C12P7/6409 , C12N9/0006 , C12N9/0008 , C12N9/0071 , C12N9/0077 , C12N15/52 , C12N15/62 , C12P7/18 , C12P7/42 , C12P7/6436 , C12Y114/14001 , C12Y114/15003 , C07K2319/00 , C12Y101/00 , C12Y102/01042 , Y02E50/10
Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
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