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公开(公告)号：US06495104B1
公开(公告)日：2002-12-17
申请号：US09377681
申请日：1999-08-19
IPC分类号： G01N1506
CPC分类号： B01L3/5027 , B01L3/502715 , B01L3/545 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/143 , B01L2300/021 , B01L2300/0816 , B01L2400/0415 , B01L2400/0487 , G01N2035/00237
摘要： Microfluidic devices and systems that include keying, registration or indication elements that communicate a functionality of the microfluidic device to the instrumentation which is used in conjunction with these devices. Indicator elements include structural indicators, electrical indicators, optical indicators and chemical indicators. Different indicator elements are indicative of different functionalities, e.g., applications, new vs. used, and the like.
摘要翻译： 微流体装置和系统包括将微流体装置的功能传递到与这些装置结合使用的仪器的键控，配准或指示元件。 指标要素包括结构指标，电气指标，光学指标和化学指标。 不同的指标元素指示不同的功能，例如应用，新的和使用的等等。
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公开(公告)号：US06811668B1
公开(公告)日：2004-11-02
申请号：US09595420
申请日：2000-06-15
IPC分类号： C02F140
CPC分类号： B01L3/502715 , B01L2200/027 , B01L2200/10 , B01L2300/0819 , B01L2400/0421
摘要： In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.
摘要翻译： 在用于操作或处理用于化学处理或分析的实验室微芯片（41）的系统中，微芯片（41）安装在第一物理单元（42）中。 微芯片（41）布置在安装板上，使得其从顶部容易接近，因此微芯片的装配和移除被大大简化。 此外，第一物理单元（42）包括用于非接触式检测在微芯片上进行的化学处理结果的光学装置（43）。 微芯片操作所需的供电系统被布置在与第二物理单元具有可分离连接的模块单元中。 所提出的模块化布局使得所需供应系统的可互换性变得容易，并且因此总体而言，所提出的系统适用于各种类型的微芯片。
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公开(公告)号：US07449096B2
公开(公告)日：2008-11-11
申请号：US10915744
申请日：2004-08-11
IPC分类号： G01N27/453 , B01L3/00
CPC分类号： B01L3/502715 , B01L2200/027 , B01L2200/10 , B01L2300/0819 , B01L2400/0421
摘要： In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.
摘要翻译： 在用于操作或处理用于化学处理或分析的实验室微芯片（41）的系统中，微芯片（41）安装在第一物理单元（42）中。 微芯片（41）布置在安装板上，使得其从顶部容易接近，因此微芯片的装配和移除被大大简化。 此外，第一物理单元（42）包括用于非接触式检测在微芯片上进行的化学处理结果的光学装置（43）。 微芯片操作所需的供电系统被布置在与第二物理单元具有可分离连接的模块单元中。 所提出的模块化布局使得所需供应系统的可互换性变得容易，并且因此总体而言，所提出的系统适用于各种类型的微芯片。
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公开(公告)号：US20050011764A1
公开(公告)日：2005-01-20
申请号：US10915744
申请日：2004-08-11
CPC分类号： B01L3/502715 , B01L2200/027 , B01L2200/10 , B01L2300/0819 , B01L2400/0421
摘要： In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.
摘要翻译： 在用于操作或处理用于化学处理或分析的实验室微芯片（41）的系统中，微芯片（41）安装在第一物理单元（42）中。 微芯片（41）设置在安装板上，使得其从顶部容易接近，因此微芯片的装配和移除被大大简化。 此外，第一物理单元（42）包括用于非接触式检测在微芯片上进行的化学处理结果的光学装置（43）。 微芯片操作所需的供电系统被布置在与第二物理单元具有可分离连接的模块单元中。 所提出的模块化布局使得所需供应系统的可互换性变得容易，并且因此总体而言，所提出的系统适用于各种类型的微芯片。
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公开(公告)号：US08438910B2
公开(公告)日：2013-05-14
申请号：US12755804
申请日：2010-04-07
申请人： Manfred Berndt
发明人： Manfred Berndt
IPC分类号： G01N30/36
CPC分类号： G01N30/20 , F16K11/074 , G01N2030/202 , Y10T29/49412 , Y10T137/86863
摘要： A shear valve for use in a high performance liquid chromatography system, the shear valve comprising a first shear valve member and a second shear valve member, wherein at least one of the first and second shear valve members is adapted to be moved with respect to the other, one of the first and second shear valve members comprises a plurality of ports, and the other comprises at least one fluid path for fluidly coupling respective ones of the ports in dependency on a relative movement position of the first and second shear valve members with respect to each other, wherein the first shear valve member is at least partially coated with an adhesion-promoting layer and a diamond like carbon layer on the adhesion-promoting layer.
摘要翻译： 一种用于高效液相色谱系统的剪切阀，所述剪切阀包括第一剪切阀构件和第二剪切阀构件，其中所述第一和第二剪切阀构件中的至少一个适于相对于所述剪切阀构件移动 另一个，第一和第二剪切阀构件中的一个包括多个端口，另一个包括至少一个流体路径，用于根据第一和第二剪切阀构件的相对运动位置流体地联接相应的端口， 彼此相对，其中第一剪切阀构件在粘附促进层上至少部分地涂覆有粘附促进层和类金刚石碳层。
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公开(公告)号：US07972576B2
公开(公告)日：2011-07-05
申请号：US12388918
申请日：2009-02-19
申请人： Sven Langer , Manfred Berndt
发明人： Sven Langer , Manfred Berndt
IPC分类号： B01L3/00
CPC分类号： G01N35/1097 , G01N30/24 , G01N35/1011 , G01N2035/1039
摘要： A fluidic device comprising a capillary for conducting a fluid and a pivot arm configured for being pivoted, wherein the pivot arm supports at least a portion of the capillary, and a part of the capillary is coiled to at least partially compensate stress resulting from pivoting of the pivot arm.
摘要翻译： 一种流体装置，包括用于传导流体的毛细管和构造成枢转的枢转臂，其中所述枢转臂支撑所述毛细管的至少一部分，并且所述毛细管的一部分被卷绕以至少部分地补偿由 枢轴臂。
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公开(公告)号：US20070154355A1
公开(公告)日：2007-07-05
申请号：US11707429
申请日：2007-02-16
申请人： Manfred Berndt , Marcus Gassmann
发明人： Manfred Berndt , Marcus Gassmann
IPC分类号： B01L3/00
CPC分类号： G01N27/44791 , B01L3/502715 , B01L3/502738 , B01L7/52 , B01L2200/027 , B01L2200/10 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2400/0421 , B01L2400/049 , B01L2400/065
摘要： US 2004/0119070A1 (D1) discloses an integrated microchip design, wherein glass microchips can be linearly moved against one another, in order to connect or disconnect capillary channels in the microchips. In contrast thereto, the invention provides a plastic material microfluidic device having an interface for coupling and flow controlling a flow path between the plastic and a second microfluidic device, which can be made e.g. of glass. This allows coupling e.g. different material microfluidic devices e.g. in order to make use of advantages of different material type microfluidic devices.
摘要翻译： US 2004 / 0119070A1（D1）公开了一种集成微芯片设计，其中玻璃微芯片可以彼此线性移动，以便连接或断开微芯片中的毛细通道。 与此相反，本发明提供了一种塑料材料微流体装置，其具有用于联接和流动控制塑料和第二微流体装置之间的流动路径的界面，该流路可以例如制成。 的玻璃。 这允许例如 不同的材料微流体装置，例如 以利用不同材料型微流体装置的优点。
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公开(公告)号：US20060008386A1
公开(公告)日：2006-01-12
申请号：US11129420
申请日：2005-05-16
申请人： Manfred Berndt
发明人： Manfred Berndt
IPC分类号： B01L3/02
CPC分类号： B01L9/527 , B01J19/0093 , B01J2219/00783 , B01J2219/0081 , B01J2219/00891 , B01L3/502715 , B01L2200/025 , B01L2200/027 , B01L2200/04 , B01L2200/10 , B01L2200/143 , B01L2300/043 , B01L2300/0645 , B01L2300/0816 , B01L2300/18 , B01L2400/0415 , B01L2400/0442 , B01L2400/0487 , Y10T436/25 , Y10T436/2575
摘要： A supply element for a laboratory microchip includes a sealed substance source. A seal in the substance source is opened in response to the supply element and the microchip being joined together. While the seal is open, the substance is transferred from the substance source to a supplier in the microchip. The substance is moved from the supplier in the microchip to the microfluid structure by applying a potential to the microchip. The supply element is releasably attached to the supply equipment by releasably attaching the supply element with a bayonet lock.
摘要翻译： 用于实验室微芯片的供应元件包括密封物质源。 响应于供给元件和微芯片接合在一起，物质源中的密封被打开。 当密封件打开时，物质从物质源转移到微芯片中的供应商。 通过向微芯片施加电位，物质从微芯片中的供应商移动到微流体结构。 供应元件通过用卡口锁定可释放地附接供应元件而可释放地附接到供应设备。
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公开(公告)号：US06258154B1
公开(公告)日：2001-07-10
申请号：US09354118
申请日：1999-07-15
IPC分类号： B01D1900
CPC分类号： B01D19/0031 , G01N30/34 , G01N2030/146
摘要： An apparatus for degassing liquids comprises a cavity through which liquid is conducted, with gas being removed from the liquid through at least one of the limiting faces of the cavity by providing on the side of the face distal to the cavity a smaller pressure than within the cavity. The apparatus is characterized in that the limiting face between the cavity and the region having reduced pressure compared to the cavity is formed by at least one thin membrane, having a thickness of less than about 10 micrometers, and in that a porous support structure for supporting the membrane is provided. The degasser can be miniaturized and integrated into a liquid chromatograph.
摘要翻译： 一种用于对液体进行脱气的装置包括一个空腔，液体通过该空腔通过至少一个空腔的限制面从液体中除去，该空气通过在远离空腔的表面的一侧提供比在 腔。 该装置的特征在于，空腔和具有与空腔相比具有减小压力的区域之间的限制面由至少一个厚度小于约10微米的薄膜形成，并且用于支撑的多孔支撑结构 提供膜。 脱气机可以小型化并集成到液相色谱仪中。
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公开(公告)号：US09039894B2
公开(公告)日：2015-05-26
申请号：US11986358
申请日：2007-11-21
申请人： Bernd Schaupp , Juergen Skott , Michael Braun , Soeren Groth , Manfred Berndt
发明人： Bernd Schaupp , Juergen Skott , Michael Braun , Soeren Groth , Manfred Berndt
IPC分类号： B01D15/08 , B01D15/12 , G01N30/04 , G01N30/20 , G01N30/30 , F04B39/14 , F04B53/22 , H05K5/00 , B01D15/10 , G06F1/18 , G01N30/60
CPC分类号： H05K5/0004 , B01D15/08 , B01D15/10 , B01D15/12 , B01L2300/06 , F04B39/14 , F04B53/22 , G01N30/04 , G01N30/20 , G01N30/30 , G01N30/6047 , G01N2030/3007 , G01N2030/3015 , G06F1/183
摘要： A supporting plate of a device is suggested. The device has at least one component and a housing for at least partly protecting the component. The supporting plate has at least one receiving element adapted for accepting the at least one component of the device in at least one of the following manners: in a form-closed manner, in a force-closed manner. The supporting plate is part of the housing.
摘要翻译： 建议装置的支撑板。 该装置具有至少一个部件和用于至少部分地保护部件的壳体。 所述支撑板具有至少一个接收元件，所述至少一个接收元件适于以至少一种以下方式接收所述装置的所述至少一个部件：以闭合方式以强制关闭方式。 支撑板是外壳的一部分。
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