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公开(公告)号：US07943388B2
公开(公告)日：2011-05-17
申请号：US10596953
申请日：2004-12-17
申请人： John P. Baetzold , Karl E. Benson , G. Marco Bommarito , Michael P. Daniels , Albert I. Everaerts , Peggy-Jean P. Flanigan , M. Benton Free , Cary A. Kipke , Brinda B. Lakshmi , Charles M. Leir , George G. I. Moore , Lang N. Nguyen , Rahul R. Shah , Peter A. Stark
发明人： John P. Baetzold , Karl E. Benson , G. Marco Bommarito , Michael P. Daniels , Albert I. Everaerts , Peggy-Jean P. Flanigan , M. Benton Free , Cary A. Kipke , Brinda B. Lakshmi , Charles M. Leir , George G. I. Moore , Lang N. Nguyen , Rahul R. Shah , Peter A. Stark
CPC分类号： G01N29/022 , B01L3/502723 , B01L3/502746 , B01L2200/04 , B01L2200/0684 , B01L2200/10 , B01L2200/16 , B01L2300/06 , B01L2300/0663 , B01L2300/0672 , B01L2300/069 , B01L2300/161 , B01L2400/0406 , B01L2400/0478 , B01L2400/0683 , B01L2400/086 , B01L2400/088 , C07C311/51 , C07D207/46 , C07D275/06 , G01N29/2462 , G01N33/54373 , G01N2291/0255 , G01N2291/0256 , G01N2291/02881 , G01N2291/0422 , G01N2291/0423 , G01N2291/0426 , G01N2291/0427 , Y10T436/141111
摘要： Acoustic sensors, preferably surface acoustic wave sensors, and more preferably shear horizontal surface acoustic wave sensors that include soluble mixed with oligomers and/or polymers formed from such monomers), or multifunctional compounds, for example, that can function as either waveguide materials, immobilization materials for secondary capture agents (e.g., antibodies), or both.
摘要翻译： 声学传感器，优选表面声波传感器，更优选剪切水平表面声波传感器，其包括可溶性聚合物，单体（任选地与由这些单体形成的低聚物和/或聚合物混合）或多官能化合物，例如可以起到 波导材料，二次捕获剂（例如，抗体）的固定化材料或两者。
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公开(公告)号：US07671155B2
公开(公告)日：2010-03-02
申请号：US12433955
申请日：2009-05-01
IPC分类号： C08F226/06 , C08F132/08
CPC分类号： C08G73/0213 , C07D209/48 , Y10T428/31855
摘要： Crosslinked polymeric materials are described that contain pendant amine capture groups. The amine capture groups include N-sulfonyldicarboximide groups that can react with amine-containing materials by a ring opening reaction. Reaction mixtures used to prepare the crosslinked polymeric materials, articles containing the crosslinked polymeric materials, methods of making articles, and methods of immobilizing an amine-containing material are also described.
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公开(公告)号：US07544756B2
公开(公告)日：2009-06-09
申请号：US11240239
申请日：2005-09-30
IPC分类号： C08F226/06 , C08F132/08
CPC分类号： C08G73/0213 , C07D209/48 , Y10T428/31855
摘要： Crosslinked polymeric materials are described that contain pendant amine capture groups. The amine capture groups include N-sulfonyldicarboximide groups that can react with amine-containing materials by a ring opening reaction. Reaction mixtures used to prepare the crosslinked polymeric materials, articles containing the crosslinked polymeric materials, methods of making articles, and methods of immobilizing an amine-containing material are also described.
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公开(公告)号：US07632903B2
公开(公告)日：2009-12-15
申请号：US12433105
申请日：2009-04-30
CPC分类号： C07D275/06 , C09D179/02 , Y10T428/31855
摘要： Crosslinked polymeric materials are described that contain pendant amine capture groups. The amine capture groups include N-sulfonylaminocarbonyl groups that can react with amine-containing materials by a nucleophilic displacement reaction. Reaction mixtures used to prepare the crosslinked polymeric materials, articles containing the crosslinked polymeric materials, methods of making articles, and methods of immobilizing an amine-containing material are also described.
摘要翻译： 描述了含有侧胺捕获基团的交联聚合物材料。 胺捕获基团包括可通过亲核置换反应与含胺材料反应的N-磺酰基氨基羰基。 还描述了用于制备交联聚合物材料的反应混合物，含有交联聚合物材料的制品，制造方法和固定含胺材料的方法。
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公开(公告)号：US07179923B2
公开(公告)日：2007-02-20
申请号：US10987522
申请日：2004-11-12
申请人： Karl E. Benson , Moses M. David , Cary A. Kipke , Brinda B. Lakshmi , Charles M. Leir , George G. I. Moore , Rahul R. Shah
发明人： Karl E. Benson , Moses M. David , Cary A. Kipke , Brinda B. Lakshmi , Charles M. Leir , George G. I. Moore , Rahul R. Shah
IPC分类号： C07D275/06 , C07C311/00 , H05H1/24 , C23C16/00
CPC分类号： G01N33/54353 , B82Y30/00 , B82Y40/00 , C07C311/51 , C07D207/46 , C07D275/06
摘要： Compounds having two reactive functional groups are described that can be used to provide a connector group between a substrate and an amine-containing material. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonylaminocarbonyl group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a carbonylimino-containing connector group. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.
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公开(公告)号：US07671154B2
公开(公告)日：2010-03-02
申请号：US12433456
申请日：2009-04-30
IPC分类号： C08F226/06 , C08F132/08
CPC分类号： C08F220/38 , Y10T428/31855
摘要： Crosslinked polymeric materials are described that contain pendant amine capture groups. The amine capture groups include N-sulfonyldicarboximide groups that can react with amine-containing materials by a ring opening reaction. Reaction mixtures used to prepare the crosslinked polymeric materials, articles containing the crosslinked polymeric materials, methods of making articles, and methods of immobilizing an amine-containing material are also described.
摘要翻译： 描述了含有侧胺捕获基团的交联聚合物材料。 胺捕获基团包括可通过开环反应与含胺材料反应的N-磺酰基二甲酰亚胺基团。 还描述了用于制备交联聚合物材料的反应混合物，含有交联聚合物材料的制品，制造方法和固定含胺材料的方法。
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公开(公告)号：US07544755B2
公开(公告)日：2009-06-09
申请号：US11239875
申请日：2005-09-30
IPC分类号： C08F226/06 , C08F132/08
CPC分类号： C08F220/38 , Y10T428/31855
摘要： Crosslinked polymeric materials are described that contain pendant amine capture groups. The amine capture groups include N-sulfonyldicarboximide groups that can react with amine-containing materials by a ring opening reaction. Reaction mixtures used to prepare the crosslinked polymeric materials, articles containing the crosslinked polymeric materials, methods of making articles, and methods of immobilizing an amine-containing material are also described.
摘要翻译： 描述了含有侧胺捕获基团的交联聚合物材料。 胺捕获基团包括可通过开环反应与含胺材料反应的N-磺酰基二甲酰亚胺基团。 还描述了用于制备交联聚合物材料的反应混合物，含有交联聚合物材料的制品，制造方法和固定含胺材料的方法。
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公开(公告)号：US07544754B2
公开(公告)日：2009-06-09
申请号：US11241028
申请日：2005-09-30
CPC分类号： C07D275/06 , C09D179/02 , Y10T428/31855
摘要： Crosslinked polymeric materials are described that contain pendant amine capture groups. The amine capture groups include N-sulfonylaminocarbonyl groups that can react with amine-containing materials by a nucleophilic displacement reaction. Reaction mixtures used to prepare the crosslinked polymeric materials, articles containing the crosslinked polymeric materials, methods of making articles, and methods of immobilizing an amine-containing material are also described.
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公开(公告)号：US07423155B2
公开(公告)日：2008-09-09
申请号：US10987075
申请日：2004-11-12
申请人： Karl E. Benson , Moses M. David , Cary A. Kipke , Brinda B. Lakshmi , Charles M. Leir , George G. I. Moore , Rahul R. Shah
发明人： Karl E. Benson , Moses M. David , Cary A. Kipke , Brinda B. Lakshmi , Charles M. Leir , George G. I. Moore , Rahul R. Shah
IPC分类号： C07D207/48 , C07D209/48 , C07D209/56 , C07D211/96 , B32B27/00
CPC分类号： C07D207/404 , B82Y30/00 , B82Y40/00 , C07D209/48 , C07D209/76 , C07D211/88 , C07D275/06 , C07D403/12 , C07D471/08 , G01N2291/0256 , G01N2291/0422 , G01N2291/0423 , G01N2291/0427 , Y10T428/2982 , Y10T428/2998 , Y10T428/31616 , Y10T428/31623 , Y10T428/31721 , Y10T428/31786
摘要： Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonyldicarboximide group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a connector group between the substrate and the amine-containing material. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.
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公开(公告)号：US08906703B2
公开(公告)日：2014-12-09
申请号：US11856140
申请日：2007-09-17
IPC分类号： G01N33/548 , G01N33/547 , G01N33/53 , C07K17/14 , C07K1/107 , C07H21/02 , G01N33/543 , C07K17/06 , C07H21/04 , C07C323/52
CPC分类号： C07K17/14 , C07C323/52 , C07H21/02 , C07H21/04 , C07K1/1077 , C07K17/06 , G01N33/54353
摘要： A method for immobilizing an amino-containing material to a substrate is described. The method involves providing a tethering compound with two reactive groups: a substrate reactive group and a fluoroalkoxycarbonyl group. The method further involves preparing a substrate-attached tethering group by reacting the substrate reactive group of the tethering compound with a complementary functional group on the surface of a substrate. The substrate-attached tethering group has a fluoroalkoxycarbonyl group that can be reacted with an amino-containing material to form an immobilization group that connects the amino-containing material to the substrate.
摘要翻译： 描述了将含氨基材料固定到基底的方法。 该方法包括提供具有两个反应性基团的系链化合物：底物反应性基团和氟代烷氧基羰基。 该方法进一步包括通过使基带化合物的底物反应性基团与基底表面上的互补官能团反应来制备基底连接的束缚基团。 底物连接基团具有可与含氨基材料反应的氟代烷氧基羰基，形成将含氨基材料与基材连接的固定基。
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