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    Anti-IL-12 antibody based vectors, host cells, and methods of production and uses
    4.
    发明授权
    Anti-IL-12 antibody based vectors, host cells, and methods of production and uses 有权
    抗IL-12抗体为载体，宿主细胞，以及生产和使用方法

    公开(公告)号：US08361474B2

    公开(公告)日：2013-01-29

    申请号：US12759154

    申请日：2010-04-13

    申请人： Jin Lu ,  Thomas Nesspor ,  Bernard Scallon ,  Linda Snyder

    发明人： Jin Lu ,  Thomas Nesspor ,  Bernard Scallon ,  Linda Snyder

    IPC分类号： A61K39/395 ,  C07H21/02 ,  C07H21/04 ,  C12N15/00 ,  C12N5/00 ,  C12N5/02 ,  C12N5/10 ,  C12P21/04

    CPC分类号： C07K16/244 ,  C07K16/00 ,  C12N15/1086 ,  C12N15/63

    摘要： Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.

    摘要翻译： 抗体表达载体和质粒可以掺入用于转录抗体DNA的各种抗体基因部分和抗体在合适的宿主细胞中的表达。 表达载体和质粒具有有利于将抗体编码DNA连接到载体中的限制酶位点。 载体包含增强子和启动子序列，其可以变化以与宿主细胞中的转录因子相互作用，从而控制抗体编码DNA的转录。 试剂盒可以并入这些载体和质粒。

    Anti-IL-12 Antibody Based Vectors, Host Cells, and Methods of Production and Uses
    5.
    发明申请
    Anti-IL-12 Antibody Based Vectors, Host Cells, and Methods of Production and Uses 有权
    抗IL-12抗体载体，宿主细胞及其生产和使用方法

    公开(公告)号：US20100216234A1

    公开(公告)日：2010-08-26

    申请号：US12759154

    申请日：2010-04-13

    申请人： Jin Lu ,  Thomas Nesspor ,  Bernard Scallon ,  Linda Snyder

    发明人： Jin Lu ,  Thomas Nesspor ,  Bernard Scallon ,  Linda Snyder

    IPC分类号： C12N5/07 ,  C12N15/63

    CPC分类号： C07K16/244 ,  C07K16/00 ,  C12N15/1086 ,  C12N15/63

    摘要： Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.

    摘要翻译： 抗体表达载体和质粒可以掺入用于转录抗体DNA的各种抗体基因部分和抗体在合适的宿主细胞中的表达。 表达载体和质粒具有有利于将抗体编码DNA连接到载体中的限制酶位点。 载体包含增强子和启动子序列，其可以变化以与宿主细胞中的转录因子相互作用，从而控制抗体编码DNA的转录。 试剂盒可以并入这些载体和质粒。

    Anti-Il-12 Antibody Based Vectors, Host Cells, and Methods of Production and Uses
    7.
    发明申请
    Anti-Il-12 Antibody Based Vectors, Host Cells, and Methods of Production and Uses 有权
    抗-II-12抗体载体，宿主细胞及其生产和使用方法

    公开(公告)号：US20080299133A1

    公开(公告)日：2008-12-04

    申请号：US11722281

    申请日：2005-12-21

    申请人： Jin Lu ,  Thomas Nesspor ,  Bernard Scallon ,  Linda Snyder

    发明人： Jin Lu ,  Thomas Nesspor ,  Bernard Scallon ,  Linda Snyder

    IPC分类号： A61K39/395 ,  C12N15/00 ,  C12N5/06 ,  C12Q1/68 ,  A61P43/00 ,  C12P21/04 ,  C07K16/18

    CPC分类号： C07K16/244 ,  C07K16/00 ,  C12N15/1086 ,  C12N15/63

    摘要： Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.

    摘要翻译： 抗体表达载体和质粒可以掺入用于转录抗体DNA的各种抗体基因部分和抗体在合适的宿主细胞中的表达。 表达载体和质粒具有有利于将抗体编码DNA连接到载体中的限制酶位点。 载体包含增强子和启动子序列，其可以变化以与宿主细胞中的转录因子相互作用，从而控制抗体编码DNA的转录。 试剂盒可以并入这些载体和质粒。