公开(公告)号：US20130320207A1

公开(公告)日：2013-12-05

申请号：US13909299

申请日：2013-06-04

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hidetoshi MOROKUMA ,  Koji ISHIGURO ,  Shun KUMANO

IPC: H01J49/04

CPC classification number: H01J49/0404 ,  H01J49/00 ,  H01J49/005 ,  H01J49/04 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/0431 ,  H01J49/0495 ,  H01J49/10 ,  H01J49/24

Abstract: Provided is a mass spectrometer capable of easy exchange of a measurement sample and suppressing a carryover. The mass spectrometer includes a mass spectrometry section, an ion source the internal pressure of which is reduced by a differential pumping from the mass spectrometry section and the ion source ionizes the sample gas, a sample container in which the sample gas is generated by vaporizing the measurement sample, a thin pipe that introduces the sample gas generated in the sample container into the ion source, an elastic tube of openable and closable that connects the sample container and the thin pipe, a pair of weirs that closes or opens the elastic tube so as to sandwich the elastic tube, and a cartridge that integrates the sample container, the thin pipe, and the elastic tube, and is detachable in a lump from a main body of the mass spectrometer.

公开(公告)号：US20180114682A1

公开(公告)日：2018-04-26

申请号：US15568529

申请日：2016-03-30

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideki HASEGAWA ,  Shun KUMANO ,  Yuichiro HASHIMOTO

IPC: H01J49/00 ,  H01J49/04

CPC classification number: H01J49/0045 ,  G01N30/30 ,  G01N30/32 ,  H01J49/0468

Abstract: For increasing a speed of fragmentation of a sample, such as a protein and a peptide, to enhance introduction efficiency into a detector, such as a mass spectrometer, a liquid feeding pump 2, a sample injector 3, and a separation column 6 that are connected via pipes are included, and further, a heating unit 4 for heating a pipe between the sample injector 3 and the separation column 6, and a pressure regulating unit 5 provided between the heating unit 4 and the separation column 6 for regulating the inner pressure of the pipe heated by the heating unit 4, are included.

公开(公告)号：US20150187554A1

公开(公告)日：2015-07-02

申请号：US14643899

申请日：2015-03-10

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hidetoshi MOROKUMA ,  Koji ISHIGURO ,  Shun KUMANO

IPC: H01J49/04 ,  H01J49/10 ,  H01J49/24 ,  H01J49/00

CPC classification number: H01J49/0404 ,  H01J49/00 ,  H01J49/005 ,  H01J49/04 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/0431 ,  H01J49/0495 ,  H01J49/10 ,  H01J49/24

Abstract: Provided is a mass spectrometer capable of easy exchange of a measurement sample and suppressing a carryover. The mass spectrometer includes a mass spectrometry section, an ion source the internal pressure of which is reduced by a differential pumping from the mass spectrometry section and the ion source ionizes the sample gas, a sample container in which the sample gas is generated by vaporizing the measurement sample, a thin pipe that introduces the sample gas generated in the sample container into the ion source, an elastic tube of openable and closable that connects the sample container and the thin pipe, a pair of weirs that closes or opens the elastic tube so as to sandwich the elastic tube, and a cartridge that integrates the sample container, the thin pipe, and the elastic tube, and is detachable in a lump from a main body of the mass spectrometer.

Abstract translation: 提供能够容易地进行交换测定样品并抑制残留物的质谱仪。 质谱仪包括质谱分析部分，离子源的内部压力通过来自质谱分析部分的差分泵浦而被离子源离子化，离子源使样品气体离子化，其中样本气体通过汽化 测量样品，将样品容器中产生的样品气体引入离子源的细管，连接样品容器和细管的可打开和关闭的弹性管，一对关闭或打开弹性管的堰 夹着弹性管，以及将样品容器，细管和弹性管整合在一起的药筒，并且能够与质谱仪的主体一体地分离。

公开(公告)号：US20130228677A1

公开(公告)日：2013-09-05

申请号：US13760284

申请日：2013-02-06

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Yohei KAWAGUCHI ,  Yuichiro HASHIMOTO ,  Masuyuki SUGIYAMA ,  Shun KUMANO ,  Akihito KANEKO ,  Masahito TOGAMI ,  Kazushige NISHIMURA ,  Hiroyuki INOUE

IPC: H01J49/26

CPC classification number: H01J49/26 ,  H01J49/0031 ,  H01J49/0036

Abstract: There is a tendency of the intensity and the shape of a spectrum to be measured transitioning with the passage of measured time, depending on the volatility and the reactivity of a component. A mass spectrometric system includes: a mass spectrometric unit that measures a specimen and outputs a mass spectrum; and an estimator that has an estimation rule on content information, the estimation rule being assigned to each component and each measurement time. The estimator estimates, based on a mass spectrum output from the mass spectrometric unit, content information on each component of a plurality of components that may be contained in the specimen in accordance with the estimation rule.

Abstract translation: 根据组分的挥发性和反应性，测量光谱的强度和形状趋于随着测量时间的流逝而过渡。 质谱系统包括：测量样品并输出质谱的质谱单位; 以及估计器，其对内容信息具有估计规则，所述估计规则被分配给每个组件和每个测量时间。 估计器基于质谱单位输出的质谱估计根据估计规则可以包含在样本中的多个分量的每个分量的内容信息。