公开(公告)号：US20200025727A1

公开(公告)日：2020-01-23

申请号：US16097145

申请日：2016-05-17

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideki HASEGAWA ,  Masako ISHIMARU ,  Masuyuki SUGIYAMA

IPC: G01N30/60

Abstract: A separation column connecting device includes: a column holder for retaining a separation column; a first fitting holder carrying a first fitting which includes a seal portion to be connected to an upstream seal portion of the separation column and connected with an upstream pipe; a second fitting holder carrying a second fitting which includes a seal portion to be connected to a downstream seal portion of the separation column and connected with a downstream pipe; a body member to which either one of the first fitting holder and the second fitting holder is fixed; a driver for moving, relative to the body member, the first fitting holder or the second fitting holder not fixed to the body member; a guide for guiding the column holder in a direction of movement driven by the driver; and an elastic body disposed between the column holder and the second fitting holder.

公开(公告)号：US20180286658A1

公开(公告)日：2018-10-04

申请号：US15763813

申请日：2015-10-09

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Kazushige NISHIMURA ,  Hiroyuki SATAKE ,  Masuyuki SUGIYAMA ,  Hideki HASEGAWA ,  Tomoyuki SAKAI

IPC: H01J49/16 ,  H01J49/26 ,  H01J49/06

CPC classification number: H01J49/165 ,  H01J49/0077 ,  H01J49/0445 ,  H01J49/062 ,  H01J49/167 ,  H01J49/26

Abstract: To reduce contamination of the apparatus with an additive and to quickly switch spraying and stopping of the additive, provided is an ion analyzer including: an ion source for ionizing a measurement target substance, a spray unit for atomizing and spraying toward the measurement target substance a liquid containing an additive that reacts with the measurement target substance; a separation analysis unit for separately analyzing an ion generated by a reaction between the measurement target substance and the additive; a detector for detecting the ion that has been separately analyzed by the separation analysis unit; and a control unit for lowering a flow rate of the additive supplied to the spray unit during a time when the additive is not necessary.

公开(公告)号：US20190148122A1

公开(公告)日：2019-05-16

申请号：US16228982

申请日：2018-12-21

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Masuyuki SUGIYAMA ,  Hideki HASEGAWA ,  Masao SUGA ,  Hiroyuki SATAKE ,  Yuichiro HASHIMOTO

IPC: H01J49/06 ,  H01J49/42

CPC classification number: H01J49/063 ,  H01J49/42

Abstract: A first rod electrode set has a first center axis, into which ions and air current are introduced. A second rod electrode set has a second center axis at a distance from the first center axis, from which the ions are discharged. A power supply applies voltages to the first rod electrode set and the second rod electrode set. The first rod electrode set and the second rod electrode set have a region where the sets overlap each other in the longitudinal direction, and form a single multipole ion guide by being combined to each other in the region. Different offset DC voltages are applied to the first rod electrode set and the second rod electrode set, respectively, and a DC potential for moving the ions to the second rod electrode set in the region is formed, the ions having been guided by the first rod electrode set.

公开(公告)号：US20150041641A1

公开(公告)日：2015-02-12

申请号：US14491298

申请日：2014-09-19

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hidetoshi MOROKUMA ,  Yuichiro HASHIMOTO ,  Masuyuki SUGIYAMA ,  Masuyoshi YAMADA ,  Hideki HASEGAWA

IPC: H01J49/00 ,  H01J49/04 ,  H01J49/10 ,  H01J49/26

CPC classification number: H01J49/0013 ,  H01J49/0031 ,  H01J49/0422 ,  H01J49/0495 ,  H01J49/10 ,  H01J49/105 ,  H01J49/24 ,  H01J49/26

Abstract: A mass spectrometer of reduced size and weight is provided which is capable to conduct highly accurate mass spectroscopy. The mass spectrometer includes an ion source adapted to ionize gas flowing in from outside in order to ionize a measurement sample and a mass spectroscopy section for separating the ionized measurement sample. The ion source has its interior reduced in pressure by differential pumping from the mass spectroscopy section and ionizes the gas when the interior pressure rises as it inhales the gas, and the mass spectroscopy section separates the ionized measurement sample when its interior pressure falls after inhale of the gas. The mass spectrometer may further include a restriction device for suppressing a flow rate of the gas the ion source inhales and an open/close device for opening and closing a flow of the gas the ion source inhales.

Abstract translation: 提供了减小尺寸和重量的质谱仪，其能够进行高精度的质谱。 质谱仪包括离子源，其适于使从外部流入的气体电离，以便电离测量样品和用于分离离子化测量样品的质谱部分。 离子源的内部通过从质谱分析部分的差分泵送而在内部减压，并且当吸入气体时内部压力升高时电离气体，质谱仪分离离子化测量样品，当其内部压力在吸入后 气体。 质谱仪还可以包括用于抑制离子源吸入的气体的流量的限制装置和用于打开和关闭离子源吸入的气体流的打开/关闭装置。

公开(公告)号：US20180025896A1

公开(公告)日：2018-01-25

申请号：US15549228

申请日：2015-02-23

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Masuyuki SUGIYAMA ,  Hideki HASEGAWA ,  Masao SUGA ,  Hiroyuki SATAKE ,  Yuichiro HASHIMOTO

IPC: H01J49/06 ,  H01J49/42

CPC classification number: H01J49/063 ,  H01J49/42

Abstract: A first rod electrode set has a first center axis, into which ions and air current are introduced. A second rod electrode set has a second center axis at a distance from the first center axis, from which the ions are discharged. A power supply applies voltages to the first rod electrode set and the second rod electrode set. The first rod electrode set and the second rod electrode set have a region where the sets overlap each other in the longitudinal direction, and form a single multipole ion guide by being combined to each other in the region. Different offset DC voltages are applied to the first rod electrode set and the second rod electrode set, respectively, and a DC potential for moving the ions to the second rod electrode set in the region is formed, the ions having been guided by the first rod electrode set.

公开(公告)号：US20190178841A1

公开(公告)日：2019-06-13

申请号：US16323168

申请日：2016-08-19

Applicant: Hitachi High-Technologies Corporation

Inventor： Kazushige NISHIMURA ,  Masuyuki SUGIYAMA ,  Hideki HASEGAWA ,  Yuichiro HASHIMOTO

IPC: G01N27/62 ,  H01J49/06 ,  H01J49/26 ,  H01J49/00 ,  H01J49/04

Abstract: An ion analysis device includes: an ion source that ionizes an analyte in a liquid sample; an ion guide into which droplets and ions produced in the ion source are introduced, the ion guide having different outlets, one outlet being an ion outlet for the ions and the other outlet being a droplet outlet for the droplets; an ion analysis unit that analyzes ions ejected from the ion outlet; a droplet measurement unit that is placed on an axis of the droplet outlet, and measures the amount of droplets; and an analysis control section that compares the amount of droplets measured at the droplet measurement unit with a threshold.

公开(公告)号：US20190079051A1

公开(公告)日：2019-03-14

申请号：US16078286

申请日：2017-02-28

Applicant: Hitachi High-Technologies Corporation

Inventor： Hiroyuki SATAKE ,  Kazushige NISHIMURA ,  Hideki HASEGAWA ,  Masuyuki SUGIYAMA

IPC: G01N27/62 ,  H01J49/06 ,  H01J49/00 ,  H01J49/16

CPC classification number: G01N27/624 ,  G01N27/622 ,  H01J49/004 ,  H01J49/068 ,  H01J49/16

Abstract: In order to make an analyzer with an ion mobility separation part have high durability and robustness, the analyzer includes an ion source, an ion mobility separation part which includes a pair of facing electrodes to which a high frequency voltage and a DC voltage are applied, and a shielding electrode which is provided between the ion source and the ion mobility separation part and to which a DC voltage is applied, wherein the shielding electrode includes an ion flow path connecting an inlet from which ions from the ion source are introduced and an outlet from which the ions are discharged thereinside, and the ion flow path is bent so that the outlet is unable to be seen from the inlet.

公开(公告)号：US20130228677A1

公开(公告)日：2013-09-05

申请号：US13760284

申请日：2013-02-06

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Yohei KAWAGUCHI ,  Yuichiro HASHIMOTO ,  Masuyuki SUGIYAMA ,  Shun KUMANO ,  Akihito KANEKO ,  Masahito TOGAMI ,  Kazushige NISHIMURA ,  Hiroyuki INOUE

IPC: H01J49/26

CPC classification number: H01J49/26 ,  H01J49/0031 ,  H01J49/0036

Abstract: There is a tendency of the intensity and the shape of a spectrum to be measured transitioning with the passage of measured time, depending on the volatility and the reactivity of a component. A mass spectrometric system includes: a mass spectrometric unit that measures a specimen and outputs a mass spectrum; and an estimator that has an estimation rule on content information, the estimation rule being assigned to each component and each measurement time. The estimator estimates, based on a mass spectrum output from the mass spectrometric unit, content information on each component of a plurality of components that may be contained in the specimen in accordance with the estimation rule.

Abstract translation: 根据组分的挥发性和反应性，测量光谱的强度和形状趋于随着测量时间的流逝而过渡。 质谱系统包括：测量样品并输出质谱的质谱单位; 以及估计器，其对内容信息具有估计规则，所述估计规则被分配给每个组件和每个测量时间。 估计器基于质谱单位输出的质谱估计根据估计规则可以包含在样本中的多个分量的每个分量的内容信息。

公开(公告)号：US20130161507A1

公开(公告)日：2013-06-27

申请号：US13726294

申请日：2012-12-24

Applicant: Hitachi High-Technologies Corporation

Inventor： Kazushige NISHIMURA ,  Yuichiro HASHIMOTO ,  Masuyuki SUGIYAMA ,  Masuyoshi YAMADA ,  Hidetoshi MOROKUMA

IPC: H01J49/26 ,  H01J49/00

CPC classification number: H01J49/105 ,  H05H1/2406 ,  H05H2001/245 ,  H05H2001/2456

Abstract: A mass spectrometer featured in including an ion source including a first electrode, a second electrode, and a dielectric unit having a sample introducing unit and a sample discharging unit and provided between the first electrode and the second electrode, a power source of ionizing a sample by a discharge generated between the first electrode and the second electrode by applying an alternating current voltage to either one of the first electrode and the second electrode, a mass spectrometry unit of analyzing an ion discharged from the sample discharging unit, and a light irradiating unit of irradiating an area of generating the discharge with light.

Abstract translation: 一种质谱仪，其特征在于包括离子源，所述离子源包括第一电极，第二电极和具有样品引入单元和样品排出单元并且设置在所述第一电极和所述第二电极之间的电介质单元， 通过对第一电极和第二电极中的任一个施加交流电压，通过对第一电极和第二电极之间产生的放电进行分析，分析从取样放出单元排出的离子的质谱分析单元和光照射单元 用光照射产生放电的区域。