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    Modular implant system containing active substances and method for the production thereof
    1.
    发明授权
    Modular implant system containing active substances and method for the production thereof 有权
    含有活性物质的模块化植入体系及其生产方法

    公开(公告)号：US08003121B1

    公开(公告)日：2011-08-23

    申请号：US10343363

    申请日：2000-08-01

    申请人： Elvira Dingeldein ,  Helmut Wahlig ,  Jörg Bauer ,  Edgar Wüst ,  Christoph Sattig

    发明人： Elvira Dingeldein ,  Helmut Wahlig ,  Jörg Bauer ,  Edgar Wüst ,  Christoph Sattig

    IPC分类号： A61L24/00 ,  A61L24/06

    CPC分类号： A61L24/0015 ,  A61L24/06 ,  A61L2300/406 ,  A61L2300/416 ,  A61L2300/44 ,  C08L33/06

    摘要： System of implant components containing active agents, wherein each component is intended to function as an additive for an implant material produced with a powdery or finely granulated starting material and/or active agents and additives.Each component is powdery or finely granulated and includes at least one powdery or finely granulated active agent or additive having a higher dosage than the desired concentration for the application. The components themselves are made of a powdery or finely granulated starting material for the implant material, as well as of the active agent or additive. The active agents can be chemotherapeutical agents, such as antibiotics, whereas the additives can be x-ray contrast materials and/or or additives that alter the physical properties of the starting material, such as its elasticity or viscosity.

    摘要翻译： 包含活性剂的植入物组分的系统，其中每个组分旨在作为用粉末状或精细粒化的原料和/或活性剂和添加剂生产的植入材料的添加剂。 每种组分是粉状或细粒化的，并且包括至少一种粉末状或细粒状的活性剂或添加剂，其用量高于所需应用浓度。 组分本身由用于植入材料以及活性剂或添加剂的粉末状或精细制粒的起始材料制成。 活性剂可以是化学治疗剂，例如抗生素，而添加剂可以是改变起始物质的物理性质的X射线对比材料和/或添加剂，例如其弹性或粘度。

    Blister pack
    5.
    发明授权
    Blister pack 有权
    吸塑包装

    公开(公告)号：US06957909B1

    公开(公告)日：2005-10-25

    申请号：US09980547

    申请日：2000-07-20

    申请人： Elvira Dingeldein ,  Helmut Wahlig ,  Christoph Sattig ,  Edgar Wüst

    发明人： Elvira Dingeldein ,  Helmut Wahlig ,  Christoph Sattig ,  Edgar Wüst

    IPC分类号： A61B19/02 ,  A61F2/46 ,  B65D75/36 ,  B65D75/58 ,  B65D77/04 ,  B65D81/32 ,  B65D71/00 ,  B01F15/00 ,  B65D69/00

    CPC分类号： B65D77/0446 ,  A61B50/33 ,  B65D75/36 ,  B65D75/366 ,  B65D75/368 ,  B65D75/58 ,  B65D81/32 ,  B65D2575/365

    摘要： Blister packaging unit (10) for at least two components packed in separate individual packages, at least one of which has a pulverulent or granular consistency, which are to be prepared before use with the further packaged component(s) in a mixer or applicator to form a ready-to-use mixture. The individual packages of the components are inserted in correspondingly pre-shaped receptacles (32; 34) in the blister (30) of a suitable film or other material and this blister is closed on the side of the open mouth of the receptacles by a cover (36) of cardboard, plastic, metal or some other suitable material which may be torn off or opened in some other manner.The component(s) having the pulverulent or granular consistency is/are packaged in a respective individual blister pack (12; 14; 16) shaped at least approximately complementarily to the associated receptacle (32) in the blister packaging unit, the blister of which has the shape of an elongate trough element (12) of plastic material tapered at at least one end in the manner of a spout, which trough element(s) comprises a separate tear-off cover (16) of cardboard, plastic, metal or some other suitable material which may be torn off or opened in some other manner.

    摘要翻译： 吸塑包装单元（10）用于至少两个组件，其包装在单独的单个包装中，其中至少一个具有粉末或颗粒状稠度，其将在与混合器或涂布器中的另外包装的组分一起使用之前制备， 形成即用型混合物。 组件的各个包装被插入适当的胶片或其他材料的泡罩（30）中相应的预形状的容器（32; 34）中，并且该泡罩在容器的敞开的嘴的一侧通过盖子 （36）的纸板，塑料，金属或一些其他合适的材料，可以以某种其他方式被撕下或打开。 具有粉状或颗粒状稠度的组分被包装在与吸塑包装单元中的相关容器（32）至少大致互补成形的相应单独的泡罩包装（12; 14; 16）中，其泡罩 具有塑料材料的细长槽元件（12）的形状，其在至少一端以喷嘴的方式逐渐变细，所述槽元件包括纸板，塑料，金属或金属的分开的撕开盖（16） 可能以某种其他方式撕下或打开的一些其他合适的材料。

    Implant material
    10.
    发明授权
    Implant material 失效
    植入材料

    公开(公告)号：US5338772A

    公开(公告)日：1994-08-16

    申请号：US901481

    申请日：1992-06-22

    申请人： Hans-Jorg Bauer ,  Gerd Bauer ,  Elvira Dingeldein ,  Helmut Wahlig

    发明人： Hans-Jorg Bauer ,  Gerd Bauer ,  Elvira Dingeldein ,  Helmut Wahlig

    IPC分类号： A61F2/00 ,  A61L27/46 ,  A61L27/56 ,  B32B3/26

    CPC分类号： A61L27/46 ,  A61L27/56 ,  A61F2/0077 ,  Y10T428/249953 ,  Y10T428/258

    摘要： The invention relates to an implant material which is based on a composite material of calcium phosphate ceramic particles and bioabsorbable polymer, in which the proportion of calcium phosphate ceramic particles is at least 50% by weight and the particles are joined to one another by polymer bridges to give a three-dimensional open-pore structure in which the particle surfaces are covered with polymer to the extent of not more than 50%. This implant material is distinguished by particularly favorable growing-in and healing-in properties.

    摘要翻译： 本发明涉及一种植入材料，其基于磷酸钙陶瓷颗粒和生物可吸收聚合物的复合材料，其中磷酸钙陶瓷颗粒的比例为至少50重量％，并且颗粒通过聚合物桥彼此连接 得到三维开孔结构，其中颗粒表面被聚合物覆盖到不大于50％的程度。 这种植入材料的特征在于特别有利的生长和愈合特性。