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    Process for producing optically active carboxylic acid
    3.
    发明授权
    Process for producing optically active carboxylic acid 失效
    光学活性羧酸的制备方法

    公开(公告)号：US4962230A

    公开(公告)日：1990-10-09

    申请号：US121247

    申请日：1987-11-16

    申请人： Hidemasa Takaya ,  Tetsuo Ohta ,  Ryoji Noyori ,  Noboru Sayo ,  Hidenori Kumobayashi ,  Susumu Akutagawa

    发明人： Hidemasa Takaya ,  Tetsuo Ohta ,  Ryoji Noyori ,  Noboru Sayo ,  Hidenori Kumobayashi ,  Susumu Akutagawa

    IPC分类号： C07C51/36 ,  C07F15/00

    CPC分类号： C07F15/0053 ,  C07C51/36

    摘要： A process for producing an optically active carboxylic acid represented by formula (I): ##STR1## wherein R.sup.1, and R.sup.2, and R.sup.3 each represents a hydrogen atom, an alkyl group, an alkenyl group, or a phenyl or naphthyl group which may have a substituent, provided that all of R.sup.1, R.sup.2, and R.sup.3 are not simultaneously a hydrogen atom; when R.sup.1 and R.sup.2 are simultaneously a hydrogen atom, then R.sup.3 is not a methyl group; and that when R.sup.3 is a hydrogen atom, then R.sup.1 and R.sup.2 are each a group other then a hydrogen atom,is disclosed, comprising asymmetrically hydrogenating an .alpha.,.beta.-unsaturated carboxylic acid represented by formula (II): ##STR2## wherein R.sup.1, R.sup.2, and R.sup.3 are the same as defined above, in the presence of a ruthenium-optically active phosphine complex as a catalyst.According to the process of the invention, the desired optically active carboxylic acids which can be widely used as raw materials for synthesizing various useful compounds, for example, as intermediates for synthesizing physiologically active substances of natural materials and also as liquid crystal materials can be industrially advantageously produced.

    Method and device for treating fine particles
    7.
    发明申请
    Method and device for treating fine particles 失效
    微粒处理方法及装置

    公开(公告)号：US20050178727A1

    公开(公告)日：2005-08-18

    申请号：US10929677

    申请日：2004-08-31

    申请人： Seiichi Takagi ,  Kazuya Hongo ,  Hiroshi Miyamoto ,  Tetsuo Ohta ,  Kazuki Inami

    发明人： Seiichi Takagi ,  Kazuya Hongo ,  Hiroshi Miyamoto ,  Tetsuo Ohta ,  Kazuki Inami

    IPC分类号： B01J19/00 ,  B01D11/02 ,  B01D11/00

    CPC分类号： B01D11/02 ,  B01D11/04 ,  B01D11/0496

    摘要： The present invention provides a method for treating fine particles contained in a first fluid comprising: feeding the first fluid containing the fine particles and a second fluid to generate two laminar flows; migrating a diffusible substance contained in the first fluid into the second fluid at an interface between the first fluid and the second fluid in the laminar flows; and separating the laminar flows into the first fluid containing the fine particles and the second fluid in a diverging region.

    摘要翻译： 本发明提供了一种处理包含在第一流体中的细颗粒的方法，包括：将含有细颗粒的第一流体和第二流体进料，以产生两个层流; 将包含在第一流体中的可扩散物质在层流中的第一流体和第二流体之间的界面处移动到第二流体中; 并将层流分离成含有细颗粒的第一流体和分散区域中的第二流体。

    MICRO FLUIDIC DEVICE, SEPARATION METHOD AND SEPARATION APPARATUS
    8.
    发明申请
    MICRO FLUIDIC DEVICE, SEPARATION METHOD AND SEPARATION APPARATUS 审中-公开
    微流体装置，分离方法和分离装置

    公开(公告)号：US20100224551A1

    公开(公告)日：2010-09-09

    申请号：US12553459

    申请日：2009-09-03

    申请人： Kazuya Hongo ,  Hiroshi Kojima ,  Tetsuo Ohta ,  Seiichi Takagi

    发明人： Kazuya Hongo ,  Hiroshi Kojima ,  Tetsuo Ohta ,  Seiichi Takagi

    IPC分类号： B01D35/30

    CPC分类号： B01D63/087 ,  B01D2325/021 ,  B01L3/502707 ,  B01L3/502753 ,  B01L2200/0647 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0877

    摘要： A micro fluidic device includes a separation membrane that has an upper surface and a lower surface opposing to each other and a side surface; a plurality of base materials that sandwiches the separation membrane; a first channel and a second channel that are partitioned from each other by the separation membrane; a first feed port that is connected to the first channel; and a first discharge port that is connected to the second channel, wherein the first channel comes into contact with at least a part of the upper surface and the lower surface of the separation membrane, the second channel comes into contact with at least a part of the side surface of the separation membrane, and a fluid is movable in a surface direction within the separation membrane.

    摘要翻译： 微流体装置包括分离膜，其具有彼此相对的上表面和下表面以及侧表面; 夹持分离膜的多个基材; 通过分离膜彼此分隔的第一通道和第二通道; 连接到第一通道的第一进料口; 以及连接到第二通道的第一排出口，其中第一通道与分离膜的上表面和下表面的至少一部分接触，第二通道与至少一部分 分离膜的侧表面和流体可以在分离膜内沿表面方向移动。

    Method and device for classifying fine particles
    9.
    发明授权
    Method and device for classifying fine particles 有权
    分级细颗粒的方法和装置

    公开(公告)号：US07328807B2

    公开(公告)日：2008-02-12

    申请号：US11113095

    申请日：2005-04-25

    申请人： Seiichi Takagi ,  Kazuki Inami ,  Tetsuo Ohta

    发明人： Seiichi Takagi ,  Kazuki Inami ,  Tetsuo Ohta

    IPC分类号： B03B5/00 ,  B03D1/00

    CPC分类号： B03B5/64 ,  B03B5/00 ,  B03B2005/405 ,  G01N15/0255 ,  G01N15/04

    摘要： The present invention provides a method for classifying fine particles, the method comprising: introducing a fine particle dispersion in which fine particles are dispersed in a liquid medium into an inlet of a microchannel having the inlet and a recovery portion; and delivering the fine particle dispersion, which has been introduced through the inlet, to the recovery portion in laminar flow, wherein delivering the fine particle dispersion includes classifying the fine particles using the difference in sedimentation speed or floatation speed among the fine particles in the fine particle dispersion. The present invention also provides a device used in the method for classifying fine particles.

    摘要翻译： 本发明提供了一种微粒分级方法，该方法包括：将细粒分散在液体介质中的微粒分散体引入到具有入口和回收部分的微通道入口; 并且将通过入口引入的细颗粒分散体输送到层流的回收部分，其中输送微粒分散体包括使用微细颗粒之间的沉淀速度或漂浮速度的差异来分级细颗粒 颗粒分散。 本发明还提供了用于分级细颗粒的方法中使用的装置。

    Method for delivering fine particle dispersion, and device for delivering fine particle dispersion
    10.
    发明授权
    Method for delivering fine particle dispersion, and device for delivering fine particle dispersion 失效
    递送微粒分散体的方法以及用于递送微粒分散体的装置

    公开(公告)号：US07182553B2

    公开(公告)日：2007-02-27

    申请号：US11067642

    申请日：2005-02-28

    申请人： Seiichi Takagi ,  Kazuki Inami ,  Tetsuo Ohta

    发明人： Seiichi Takagi ,  Kazuki Inami ,  Tetsuo Ohta

    IPC分类号： B65G53/16

    CPC分类号： B01J19/0093 ,  B01J8/0015 ,  B01J2208/00752 ,  B01J2219/00011 ,  B01J2219/00247 ,  B01J2219/00891 ,  Y10T137/87652

    摘要： Disclosed is a method of delivering a fine particle dispersion in the state of laminar flow from an inlet port to an outlet port of a microflow channel having the inlet port and the outlet port, the fine particle dispersion containing fine particles having a volume average particle size of from about 1.5 μm to about 1000 μm dispersed in its liquid medium, the specific gravity of the fine particles being from approximately 0.10 to 0.99 times that of the liquid medium, wherein the microflow channel is disposed such that the outlet port is disposed above the inlet port in the buoyant force direction, and the angle of the flow channel from the inlet port to the outlet port is set to from approximately 0 to 45° relative to the buoyant force direction, and wherein the fine particle dispersion is introduced into the inlet port and the introduced fine particle dispersion is delivered to the outlet port. Also disclosed is a device for delivering the fine particle dispersion.

    摘要翻译： 公开了一种以层流状态从具有入口和出口的微流通道的入口到出口输送细粒分散体的方法，该微粒分散体含有具有体积平均粒径的微粒 分散在其液体介质中的约1.5μm至约1000μm的细颗粒的比重为液体介质的比重的约0.10至0.99倍，其中微流道被设置为使出口位于 入口端口在浮力方向上，并且从入口到出口的流动通道的角度相对于浮力力方向设定为大约0至45°，并且其中细颗粒分散体被引入入口 将引入的微粒分散体输送到出口。 还公开了用于递送细颗粒分散体的装置。