MASS SPECTROMETER AND MASS ANALYZING METHOD
    2.
    发明申请
    MASS SPECTROMETER AND MASS ANALYZING METHOD 有权
    质谱仪和质谱分析方法

    公开(公告)号:US20120326022A1

    公开(公告)日:2012-12-27

    申请号:US13527627

    申请日:2012-06-20

    IPC分类号: H01J49/04

    CPC分类号: H01J49/0409 H01J49/0495

    摘要: A mass spectrometer including a sample attaching member of attaching a sample, an ionizing chamber including an introductory port of the sample attaching member and an ionization source of generating a sample ion, a vacuumed chamber having a mass analyzer of analyzing the sample ion, and an opening/closing mechanism provided between the ionizing chamber and the vacuumed chamber, in which the opening/closing mechanism is controlled from a closed state to an open state after introducing the sample attaching member into the ionizing chamber to thereby enable to perform ionization with inconsiderable fragmentation at a high sensitivity with a high throughput

    摘要翻译: 一种质谱仪,包括附着样品的样品附着构件,包括样品附着构件的入口的电离室和产生样品离子的离子源,具有分析样品离子的质量分析器的真空室,以及 设置在离子化室和真空室之间的开/关机构,其中将样品附着构件引入电离室之后,将开/关机构从关闭状态控制到打开状态,从而能够以不可分割的碎片进行电离 灵敏度高,吞吐量高

    Mass spectrometer and mass analyzing method
    4.
    发明授权
    Mass spectrometer and mass analyzing method 有权
    质谱仪和质量分析方法

    公开(公告)号:US09184037B2

    公开(公告)日:2015-11-10

    申请号:US13527627

    申请日:2012-06-20

    IPC分类号: H01J49/00 H01J49/04

    CPC分类号: H01J49/0409 H01J49/0495

    摘要: A mass spectrometer including a sample attaching member of attaching a sample, an ionizing chamber including an introductory port of the sample attaching member and an ionization source of generating a sample ion, a vacuumed chamber having a mass analyzer of analyzing the sample ion, and an opening/closing mechanism provided between the ionizing chamber and the vacuumed chamber, in which the opening/closing mechanism is controlled from a closed state to an open state after introducing the sample attaching member into the ionizing chamber to thereby enable to perform ionization with inconsiderable fragmentation at a high sensitivity with a high throughput.

    摘要翻译: 一种质谱仪,包括附着样品的样品附着构件,包括样品附着构件的入口的电离室和产生样品离子的离子源,具有分析样品离子的质量分析器的真空室,以及 设置在离子化室和真空室之间的开/关机构,其中将样品附着构件引入电离室之后,将开/关机构从关闭状态控制到打开状态,从而能够以不可分割的碎片进行电离 灵敏度高,吞吐量高。

    Mass spectrometer
    5.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号:US08866070B2

    公开(公告)日:2014-10-21

    申请号:US13289633

    申请日:2011-11-04

    摘要: A mass spectrometer of reduced size and weight is provided which is capable to conduct highly accurate mass spectroscopy. The mass spectrometer includes an ion source adapted to ionize gas flowing in from outside in order to ionize a measurement sample and a mass spectroscopy section for separating the ionized measurement sample. The ion source has its interior reduced in pressure by differential pumping from the mass spectroscopy section and ionizes the gas when the interior pressure rises as it inhales the gas, and the mass spectroscopy section separates the ionized measurement sample when its interior pressure falls after inhale of the gas. The mass spectrometer may further include a restriction device for suppressing a flow rate of the gas the ion source inhales and an open/close device for opening and closing a flow of the gas the ion source inhales.

    摘要翻译: 提供了减小尺寸和重量的质谱仪,其能够进行高精度的质谱。 质谱仪包括离子源,其适于使从外部流入的气体电离,以便电离测量样品和用于分离离子化测量样品的质谱部分。 离子源的内部通过从质谱分析部分的差分泵送而在内部减压,并且当吸入气体时内部压力升高时电离气体,质谱仪分离离子化测量样品,当其内部压力在吸入后 气体。 质谱仪还可以包括用于抑制离子源吸入的气体的流量的限制装置和用于打开和关闭离子源吸入的气体流的打开/关闭装置。

    Mass Spectrometer
    6.
    发明申请
    Mass Spectrometer 审中-公开
    质谱仪

    公开(公告)号:US20130032711A1

    公开(公告)日:2013-02-07

    申请号:US13565286

    申请日:2012-08-02

    IPC分类号: H01J49/26

    CPC分类号: H01J49/0013

    摘要: A unit which calculates a diameter of a throttle part of a valve and a diameter of an orifice from changes of vacuum degrees measured by vacuum gauges disposed in an ion source and a vacuum chamber having a mass analysis part in order to maintain a flow rate of reagent gas flowing in the ion source to be always fixed and changes vacuum degree in a reagent introduction part, the ion source or the vacuum chamber in order to correct difference from standard value is provided. A unit which measures discharge voltage, discharge current and plasma luminous intensity to grasp current situation in order to maintain plasma generation state in the ion source to be fixed and changes discharge condition such as discharge voltage in order to correct change part from standard value is provided.

    摘要翻译: 根据设置在离子源中的真空计测量的真空度的变化和具有质量分析部的真空室,计算阀的节流部分的直径和孔的直径的单元,以便保持流量 提供了在离子源中流动的反应气体总是固定的,并且改变了试剂导入部分,离子源或真空室中的真空度,以便校正与标准值的差异。 提供测量放电电压,放电电流和等离子体发光强度的单元,以掌握当前情况,以便保持离子源中的等离子体产生状态被固定,并且改变放电电压等放电条件以便将变化部分与标准值进行校正 。

    MASS SPECTROMETER AND MASS SPECTROMETRY METHOD
    9.
    发明申请
    MASS SPECTROMETER AND MASS SPECTROMETRY METHOD 审中-公开
    质谱仪和质谱方法

    公开(公告)号:US20110248157A1

    公开(公告)日:2011-10-13

    申请号:US13123901

    申请日:2009-10-13

    IPC分类号: H01J49/42

    CPC分类号: H01J49/063 H01J49/4215

    摘要: Objects of the present invention is to provide a quadrupole mass filter that can be fabricated at low cost and has a high transmission efficiency even under a high pressure (0.5 mTorr or more), and to provide a mass spectrometer or mass spectrometry method that reduces crosstalk in a wide mass range. Now, in a mass spectrometer, an ion separating unit is configured to include quadrupole rod electrodes that form a quadrupole radio-frequency electric field, electrodes that form a quadrupole electrostatic field, and a power supply that allows the voltage of the electrodes to form a quadrupole electrostatic field to change. In a collision cell configured to perform collision induced dissociation, harmonic potentials in a plurality of stages are produced to resonance excite ions in the axial direction, so that the ions obtain kinetic energy to move in the direction of the detector. This energy allows a time period to shorten for which ions stay in the collision cell.

    摘要翻译: 本发明的目的是提供一种即使在高压(0.5mTorr以上)下也能低成本制造且具有高透射率的四极质量过滤器,并提供降低串扰的质谱仪或质谱法 在广泛的质量范围。 现在,在质谱仪中,离子分离单元被构造为包括形成四极射频电场的四极杆电极,形成四极静电场的电极和允许电极的电压形成的电源 四极静电场改变。 在被配置为执行碰撞诱导解离的碰撞单元中,产生多个级中的谐波电位以使轴向上的激发离子共振,使得离子获得沿检测器的方向移动的动能。 该能量允许缩短时间段,离子停留在碰撞池中。

    DRUG DETECTION EQUIPMENT
    10.
    发明申请
    DRUG DETECTION EQUIPMENT 有权
    药物检测设备

    公开(公告)号:US20120049055A1

    公开(公告)日:2012-03-01

    申请号:US13214654

    申请日:2011-08-22

    IPC分类号: H01J49/04 H01J49/26

    CPC分类号: H01J49/04

    摘要: The mass spectrometer includes an ion source; a mass spectrometry part; a sample container; a heater for the sample container; a first gas tube connected to the sample container to introduce a gas into the sample container; and a second gas tube connected to the sample container to transfer a headspace gas of the sample container to the ion source, in which the ion source generates ions of the headspace gas and the mass spectrometry part performs mass spectrometry of the ions.Thereby, the mass spectrometer as a drug detection equipment can analyze various drugs in urine rapidly and with high sensitivity.

    摘要翻译: 质谱仪包括离子源; 质谱部分; 样品容器 用于样品容器的加热器; 连接到样品容器以将气体引入样品容器中的第一气体管; 以及连接到样品容器以将样品容器的顶空气体转移到离子源的第二气体管,其中离子源产生顶空气体的离子,并且质谱部分进行离子的质谱分析。 因此,作为药物检测装置的质谱仪可以快速,高灵敏度地分析尿液中的各种药物。