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41 条记录 (耗时 0.035 秒)

    Apparatus for auto-pretreating sugar chain
    5.
    发明授权
    Apparatus for auto-pretreating sugar chain 有权
    用于自动预处理糖链的装置

    公开(公告)号：US08877454B2

    公开(公告)日：2014-11-04

    申请号：US12681573

    申请日：2008-10-03

    申请人： Shinichiro Nishimura ,  Yasuro Shinohara ,  Yoshiaki Miura ,  Hiroshi Yamazaki ,  Michio Horiuchi ,  Hiroaki Motoki ,  Toshiharu Kuroda ,  Yoko Kita ,  Mika Nakano

    发明人： Shinichiro Nishimura ,  Yasuro Shinohara ,  Yoshiaki Miura ,  Hiroshi Yamazaki ,  Michio Horiuchi ,  Hiroaki Motoki ,  Toshiharu Kuroda ,  Yoko Kita ,  Mika Nakano

    IPC分类号： C12Q1/37 ,  G01N33/68 ,  G01N30/72 ,  H01J49/00

    CPC分类号： G01N33/6848 ,  G01N30/7233 ,  G01N2400/00 ,  H01J49/00

    摘要： To provide an autoanalyzer for analyzing a sugar chain contained in a biological sample, in particular, serum. Namely, it is intended to provide a method of analyzing a sugar chain in a sample, which comprises the following steps: A) the sugar chain-releasing step of releasing the sugar chain in the sample; B) the detection sample-preparing step of preparing the released sugar chain for detection; and, in the case of conducting mass spectrometry using a plate, C) the step of forming a plate for the mass spectrometry having the captured sugar chain dotted thereon which comprises the step of providing the tagged sugar chain sample solution obtained in the step B) on a collection plate; and, if required, the step of conducting an operation in a solid phase support-enclosed plate to form the plate for mass spectrometry; and D) the step of analyzing the sugar chain to be assayed.

    摘要翻译： 提供一种用于分析生物样品，特别是血清中所含的糖链的自动分析仪。 即，提供一种分析样品中的糖链的方法，其包括以下步骤：A）释放样品中的糖链的糖链释放步骤; B）制备释放的糖链进行检测的检测样品制备步骤; 并且在使用板进行质谱分析的情况下，C）形成具有点状捕获的糖链的用于质谱的板的步骤，其包括提供步骤B）中获得的标记的糖链样品溶液的步骤， 在收集板上; 如果需要，在固相支持封闭板中进行操作以形成质谱板的步骤; 和D）分析要测定的糖链的步骤。

    APPARATUS FOR AUTO-PRETREATING SUGAR CHAIN
    6.
    发明申请
    APPARATUS FOR AUTO-PRETREATING SUGAR CHAIN 有权
    用于自动预处理糖链的装置

    公开(公告)号：US20110111443A1

    公开(公告)日：2011-05-12

    申请号：US12681573

    申请日：2008-10-03

    申请人： Shinichiro Nishimura ,  Yasuro Shinohara ,  Yoshiaki Miura ,  Hiroshi Yamazaki ,  Michio Horiuchi ,  Hiroaki Motoki ,  Toshiharu Kuroda ,  Yoko Kita ,  Mika Nakano

    发明人： Shinichiro Nishimura ,  Yasuro Shinohara ,  Yoshiaki Miura ,  Hiroshi Yamazaki ,  Michio Horiuchi ,  Hiroaki Motoki ,  Toshiharu Kuroda ,  Yoko Kita ,  Mika Nakano

    IPC分类号： C12Q1/37 ,  C12M1/34 ,  C12P19/00 ,  C40B60/14

    CPC分类号： G01N33/6848 ,  G01N30/7233 ,  G01N2400/00 ,  H01J49/00

    摘要： To provide an autoanalyzer for analyzing a sugar chain contained in a biological sample, in particular, serum. Namely, it is intended to provide a method of analyzing a sugar chain in a sample, which comprises the following steps: A) the sugar chain-releasing step of releasing the sugar chain in the sample; B) the detection sample-preparing step of preparing the released sugar chain for detection; and, in the case of conducting mass spectrometry using a plate, C) the step of forming a plate for the mass spectrometry having the captured sugar chain dotted thereon which comprises the step of providing the tagged sugar chain sample solution obtained in the step B) on a collection plate; and, if required, the step of conducting an operation in a solid phase support-enclosed plate to form the plate for mass spectrometry; and D) the step of analyzing the sugar chain to be assayed.

    摘要翻译： 提供一种用于分析生物样品，特别是血清中所含的糖链的自动分析仪。 即，提供一种分析样品中的糖链的方法，其包括以下步骤：A）释放样品中的糖链的糖链释放步骤; B）制备释放的糖链进行检测的检测样品制备步骤; 并且在使用板进行质谱分析的情况下，C）形成具有点状捕获的糖链的用于质谱的板的步骤，其包括提供步骤B）中获得的标记的糖链样品溶液的步骤， 在收集板上; 如果需要，在固相支持封闭板中进行操作以形成质谱板的步骤; 和D）分析要测定的糖链的步骤。

    Polymer particle
    7.
    发明授权
    Polymer particle 失效
    聚合物颗粒

    公开(公告)号：US07985874B2

    公开(公告)日：2011-07-26

    申请号：US10594182

    申请日：2005-03-18

    申请人： Shinichiro Nishimura ,  Hideyuki Shimaoka

    发明人： Shinichiro Nishimura ,  Hideyuki Shimaoka

    IPC分类号： C01B21/14

    CPC分类号： G01N33/543 ,  G01N2400/00

    摘要： A support comprising functional groups supported therein that specifically react with an aldehyde group of a sugar chain, and a polymer particle and a glycochip to which the support is applied, and uses thereof.

    摘要翻译： 其中包含与糖链的醛基特异性反应的官能团的载体，以及应用了载体的聚合物颗粒和糖芯片及其用途。

    Oxylamino Group-Containing Compound and Polymer
    9.
    发明申请
    Oxylamino Group-Containing Compound and Polymer 有权
    含氧基氨基的化合物和聚合物

    公开(公告)号：US20080097061A1

    公开(公告)日：2008-04-24

    申请号：US11660985

    申请日：2005-07-07

    申请人： Shinichiro Nishimura ,  Hideyuki Shimaoka

    发明人： Shinichiro Nishimura ,  Hideyuki Shimaoka

    IPC分类号： C08F20/04 ,  C07C49/203 ,  C07C69/52 ,  C07D207/46 ,  C07D233/02

    CPC分类号： C08F220/60 ,  C07C291/04 ,  C08F222/1006

    摘要： An oxylamino group-containing compound represented by the following formula: R1—B-A-B—R2, wherein R1 represents a polymerizable group, R2 represents an oxylamino group-containing group or an oxylamino derivative-containing group, B represents an ester linkage or an amide linkage, and A represents an optionally substituted alkylene group having 2 to 12 carbon atoms.

    摘要翻译： 由下式表示的含氧基氨基的化合物：<？in-line-formula description =“In-line formula”end =“lead”？> R 1 -BABR < / SUP>，<？in-line-formula description =“In-line Formulas”end =“tail”？>其中R 1表示可聚合基团R 2 表示含有氧基氨基的基团或含氧基氨基衍生物的基团，B表示酯键或酰胺键，A表示任选取代的碳原子数2〜12的亚烷基。

    Oxylamino group-containing compound and polymer
    10.
    发明授权
    Oxylamino group-containing compound and polymer 有权
    含氧基氨基的化合物和聚合物

    公开(公告)号：US07964687B2

    公开(公告)日：2011-06-21

    申请号：US11660985

    申请日：2005-07-07

    申请人： Shinichiro Nishimura ,  Hideyuki Shimaoka

    发明人： Shinichiro Nishimura ,  Hideyuki Shimaoka

    IPC分类号： C08F120/58

    CPC分类号： C08F220/60 ,  C07C291/04 ,  C08F222/1006

    摘要： An oxylamino group-containing compound represented by the following formula: R1—B-A-B—R2, wherein R1 represents a polymerizable group, R2 represents an oxylamino group-containing group or an oxylamino derivative-containing group, B represents an ester linkage or an amide linkage, and A represents an optionally substituted alkylene group having 2 to 12 carbon atoms.

    摘要翻译： 由下式表示的含氧基氨基的化合物：R1-BAB-R2，其中R1表示可聚合基团，R2表示含氧基氨基的基团或含氧基氨基衍生物的基团，B表示酯键或酰胺键 A表示任选取代的碳原子数2〜12的亚烷基。