Predetermined site luminescence measuring method, predetermined site luminescence measuring apparatus, expression amount measuring method, and measuring apparatus
    1.
    发明授权
    Predetermined site luminescence measuring method, predetermined site luminescence measuring apparatus, expression amount measuring method, and measuring apparatus 有权
    预定位点发光测定方法,预定位点发光测定装置,表达量测定方法及测定装置

    公开(公告)号:US08280142B2

    公开(公告)日:2012-10-02

    申请号:US13164208

    申请日:2011-06-20

    IPC分类号: G06K9/00

    摘要: An object of the present invention is to provide a predetermined site luminescence measuring method and a predetermined site luminescence measuring apparatus, which allow for determining whether, when the luminescence from the predetermined site in live samples is measured, a photoprotein is localized at the predetermined site in the same ones as the samples. An predetermined site luminescence measuring apparatus 100 in the present invention is comprised of: a the sample 102 into which a fused fusion gene is introduced, the fusion gene being obtained by fusing a fluorescence-related gene that expresses a fluorescence protein in addition to a targeting base sequence and a luminescence-related gene; a container 103 for storing the sample 102, a stage 104 on which the container 103 is arranged; a luminescent image capturing unit 106 which captures a luminescent image of the sample 102 (the objective lens 106a to the CCD camera 106c, and the imaging lens 106f); a fluorescent image capturing unit 108 which captures a fluorescent image of the sample 102 (the objective lens 108a to shutter 108f); and an the information communication terminal 110.

    摘要翻译: 本发明的目的是提供一种预定的现场发光测量方法和预定的现场发光测量装置,其允许确定当测量活样品中来自预定部位的发光时,光蛋白定位在预定位置 与样品相同。 本发明的预定位点发光测定装置100包括:融合融合基因导入到其中的样品102,所述融合基因除了靶向外,还融合表达荧光蛋白的荧光相关基因 碱基序列和发光相关基因; 用于存储样品102的容器103,设置容器103的载物台104; 捕获样品102(物镜106a到CCD照相机106c和成像透镜106f)的发光图像的发光图像捕获单元106。 捕获样品102(物镜108a至快门108f)的荧光图像的荧光图像捕获单元108; 和信息通信终端110。

    Predetermined Site Luminescence Measuring Method, Predetermined Site Luminescence Measuring Apparatus, Expression Amount Measuring Method, and Measuring Apparatus
    2.
    发明申请
    Predetermined Site Luminescence Measuring Method, Predetermined Site Luminescence Measuring Apparatus, Expression Amount Measuring Method, and Measuring Apparatus 有权
    预定位点发光测量方法,预定位点发光测量装置,表达量测量方法和测量装置

    公开(公告)号:US20090274360A1

    公开(公告)日:2009-11-05

    申请号:US11887468

    申请日:2006-03-30

    IPC分类号: G06T7/00 G06K9/20

    摘要: An object of the present invention is to provide a predetermined site luminescence measuring method and a predetermined site luminescence measuring apparatus, which allow for determining whether, when the luminescence from the predetermined site in live samples is measured, a photoprotein is localized at the predetermined site in the same ones as the samples. An predetermined site luminescence measuring apparatus 100 in the present invention is comprised of: a the sample 102 into which a fused fusion gene is introduced, the fusion gene being obtained by fusing a fluorescence-related gene that expresses a fluorescence protein in addition to a targeting base sequence and a luminescence-related gene; a container 103 for storing the sample 102, a stage 104 on which the container 103 is arranged; a luminescent image capturing unit 106 which captures a luminescent image of the sample 102 (the objective lens 106a to the CCD camera 106c, and the imaging lens 106f); a fluorescent image capturing unit 108 which captures a fluorescent image of the sample 102 (the objective lens 108a to shutter 108f); and an the information communication terminal 110.

    摘要翻译: 本发明的目的是提供一种预定的现场发光测量方法和预定的现场发光测量装置,其允许确定当测量活样品中来自预定部位的发光时,光蛋白定位在预定位置 与样品相同。 本发明的预定位点发光测定装置100包括:融合融合基因导入到其中的样品102,所述融合基因除了靶向外,还融合表达荧光蛋白的荧光相关基因 碱基序列和发光相关基因; 用于存储样品102的容器103,设置容器103的载物台104; 捕获样品102(物镜106a到CCD照相机106c和成像透镜106f)的发光图像的发光图像捕获单元106。 捕获样品102(物镜108a至快门108f)的荧光图像的荧光图像捕获单元108; 和信息通信终端110。

    Predetermined site luminescence measuring method, predetermined site luminescence measuring apparatus, expression amount measuring method, and measuring apparatus
    3.
    发明授权
    Predetermined site luminescence measuring method, predetermined site luminescence measuring apparatus, expression amount measuring method, and measuring apparatus 有权
    预定位点发光测定方法,预定位点发光测定装置,表达量测定方法及测定装置

    公开(公告)号:US07986824B2

    公开(公告)日:2011-07-26

    申请号:US11887468

    申请日:2006-03-30

    IPC分类号: G06K9/00

    摘要: An object of the present invention is to provide a predetermined site luminescence measuring method and a predetermined site luminescence measuring apparatus, which allow for determining whether, when the luminescence from the predetermined site in live samples is measured, a photoprotein is localized at the predetermined site in the same ones as the samples. An predetermined site luminescence measuring apparatus 100 in the present invention is comprised of: a the sample 102 into which a fused fusion gene is introduced, the fusion gene being obtained by fusing a fluorescence-related gene that expresses a fluorescence protein in addition to a targeting base sequence and a luminescence-related gene; a container 103 for storing the sample 102, a stage 104 on which the container 103 is arranged; a luminescent image capturing unit 106 which captures a luminescent image of the sample 102 (the objective lens 106a to the CCD camera 106c, and the imaging lens 106f); a fluorescent image capturing unit 108 which captures a fluorescent image of the sample 102 (the objective lens 108a to shutter 108f); and an the information communication terminal 110.

    摘要翻译: 本发明的目的是提供一种预定的现场发光测量方法和预定的现场发光测量装置,其允许确定当测量活样品中来自预定部位的发光时,光蛋白定位在预定位置 与样品相同。 本发明的预定位点发光测定装置100包括:融合融合基因导入到其中的样品102,所述融合基因除了靶向外,还融合表达荧光蛋白的荧光相关基因 碱基序列和发光相关基因; 用于存储样品102的容器103,设置容器103的载物台104; 捕获样品102(物镜106a到CCD照相机106c和成像透镜106f)的发光图像的发光图像捕获单元106。 捕获样品102(物镜108a至快门108f)的荧光图像的荧光图像捕获单元108; 和信息通信终端110。

    Optical apparatus provided with correction collar for aberration correction and imaging method using same
    5.
    发明授权
    Optical apparatus provided with correction collar for aberration correction and imaging method using same 有权
    具有用于像差校正的校正环和使用其的成像方法的光学装置

    公开(公告)号:US07825360B2

    公开(公告)日:2010-11-02

    申请号:US12150536

    申请日:2008-04-29

    IPC分类号: G02B7/04 G02B27/40 G02B27/64

    摘要: This is an optical apparatus provided with an objective with a correction collar for correcting aberration due to an error in the optical thickness of a piece of cover glass comprising a focusing mechanism for changing a distance between the objective and the sample, an optical thickness detecting unit for detecting the optical thickness of the cover glass, an operating unit for calculating the amount of aberration correction, based on the optical thickness of the cover glass detected by the optical thickness detecting unit, a driver unit for driving a correction collar, based on the amount of aberration correction calculated by the operating unit and an imaging sensor for forming the image of the sample that passes through the objective.

    摘要翻译: 这是一种光学装置,其具有用于校正由于包括用于改变物镜和样品之间的距离的聚焦机构的玻璃片的光学厚度的误差引起的像差的校正环的物镜,光学厚度检测单元 用于检测盖玻璃的光学厚度的操作单元,用于基于由光学厚度检测单元检测到的盖玻璃的光学厚度计算像差校正量的操作单元,用于驱动校正环的驱动单元,基于 由操作单元计算的像差校正量和用于形成通过物镜的样本的图像的成像传感器。

    Microscope and lamphouse
    6.
    发明申请
    Microscope and lamphouse 审中-公开
    显微镜和灯箱

    公开(公告)号:US20070091939A1

    公开(公告)日:2007-04-26

    申请号:US11586033

    申请日:2006-10-25

    IPC分类号: H01S3/00

    CPC分类号: G02B21/06

    摘要: A microscope includes an illuminating unit that includes an excitation light source emitting an excitation light, and a phosphor receiving the excitation light and emitting illumination light in a specific wavelength range. The illuminating unit illuminates a specimen with the illumination light. The microscope also includes an observation unit for observing the specimen illuminated by the illuminating unit.

    摘要翻译: 显微镜包括包括发射激发光的激发光源的照明单元和接收激发光并发射特定波长范围的照明光的荧光体。 照明单元用照明光照亮样本。 显微镜还包括观察由照明单元照射的样本的观察单元。