Antibiotic substances DC-45, and their use as medicaments
    6.
    发明授权
    Antibiotic substances DC-45, and their use as medicaments 失效
    抗生素DC-45及其作为药物的用途

    公开(公告)号:US4511560A

    公开(公告)日:1985-04-16

    申请号:US412693

    申请日:1982-08-30

    CPC分类号: C12R1/465 C12P1/06

    摘要: New substances designated as DC-45-A, DC-45-B.sub.1 and DC-45-B.sub.2 and represented by the following general formula: ##STR1## wherein (i) R.sub.1 and R.sub.2 together with the carbon atom therebetween represent the group ##STR2## and R.sub.3 represents ##STR3## (designated DC-45-A); (ii) R.sub.1 represents --OH, R.sub.2 represents --CH.sub.2 OH and R.sub.3 represents ##STR4## (designated DC-45-B.sub.1); or (iii) R.sub.1 and R.sub.2 together with the carbon atom therebetween represent the group ##STR5## and R.sub.3 represents ##STR6## (designated DC-45-B.sub.2). DC-45-A, DC-45-B.sub.1 and DC-45-B.sub.2 possess antibiotic and anti-tumor activity and may be obtained by culturing a microorganism of the genus Streptomyces. Preferred strain is Streptomyces bottropensis (FERM-P No. 5219; NRRL 12051).

    摘要翻译: 指定为DC-45-A,DC-45-B1和DC-45-B2的新物质,由以下通式表示:其中(i)R 1和R 2与它们之间的碳原子代表基团(指定为DC-45-A); (ii)R 1表示-OH,R 2表示-CH 2 OH,R 3表示(指定为DC-45-B1)。 或(iii)R 1和R 2与它们之间的碳原子代表基团,并且R 3代表“IMAGE”(指定为DC-45-B2)。 DC-45-A,DC-45-B1和DC-45-B2具有抗生素和抗肿瘤活性,可以通过培养链霉菌属的微生物获得。 优选的菌株是巴斯德链霉菌(FERM-P No.5219; NRRL 12051)。

    Opposed piston type disc brake
    7.
    发明申请
    Opposed piston type disc brake 审中-公开
    反向活塞式盘式制动器

    公开(公告)号:US20070278049A1

    公开(公告)日:2007-12-06

    申请号:US11806345

    申请日:2007-05-31

    IPC分类号: F16D65/38

    摘要: A coupling member configured to bridge outer and inner body portions 3c, 4c in a state of hampering the outer and inner body portions 3c, 4c from being displaced in directions of separating the outer and inner body portions 3c, 4c is constituted by a bridge portion 20a integral with a caliper 5c including the outer and inner body portions 3c, 4c. Further, a brake torque applied to the inner and outer pads 11a, 12a is supported by outer side coupling pins 13a, 13a configured to bridge two end portions of the outer and inner body portions 3c, 4c.

    摘要翻译: 一种联接构件,其构造成在妨碍外部主体部分3c和内部主体部分4c的状态下使外部主体部分3c和内部主体部分4c夹紧,从而在分离外部主体部分3c和内部主体部分4c的方向上移位 由与包括外主体部分3c和内主体部分4c的卡钳5c成一体的桥部分20a构成。 此外,施加到内垫片和外垫片11a,12a的制动扭矩由外侧联接销钉13aa,13a支撑,外侧联接销钉13aa,13aa构造成桥接外主体部分3c和内主体部分3c的两个端部。